calendula officinalis flower oil CO2 extract
marigold pot flower oil CO2 extract
 
Notes:
tsca definition 2008: extractives and their physically modified derivatives. calendula officinalis, compositae.
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Name: calendula officinalis l. flower oil CO2 extract
CAS Number: 70892-20-5 
Also Contains: calendula officinalis flower extract
Category: cosmetic and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: reddish yellow to amber brown liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 0.91000 to 0.93000 @  25.00 °C.
Pounds per Gallon - (est).: 7.572 to  7.739
Boiling Point: 350.00 to  353.00 °C. @ 760.00 mm Hg
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
Insoluble in:
 water
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Organoleptic Properties:
 
Odor Type: herbal
 
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 
 herbal  floral  woody  balsamic  
Odor Description:
at 10.00 % in dipropylene glycol. 
herbal floral woody balsamic
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: fragrance
perfuming agents
skin conditioning
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Suppliers:
Absolute Cosmetic Essentials
Marigold Flower CO2-to ext <0,1%
FLAVEX Naturextrakte
Marigold Flower CO2-to extract (integr), < 0,1 % Carotenoides, Type No. 018.010
Odor: characteristic
Use: n cosmetics and pharmaceuticals, for treatment of hurts, bruises and inflammations, for wound healing and increasing the granulation, for dry sensitive skin, in face creams, sun lotions, lipsticks, hair shampoos, bath additives [2]. Dosage: 0,1 - 0,3 %.
FLAVEX Naturextrakte
Marigold Flower CO2-to extract (integr), Type No. 018.001
Odor: characteristic
Use: In cosmetics and pharmaceuticals, for treatment of hurts, bruises and inflammations, for wound healing and increasing the granulation, for dry sensitive skin, in face creams, sun lotions, lipsticks, hair shampoos, bath additives [2]. Dosage: 0,1 - 0,3 %.
FLAVEX Naturextrakte
Marigold Flower CO2-to extract (organic), < 0,1 % Carotenoides, DE-OKO-013
Odor: characteristic
Use: Marigold flowers (Calendula officinalis) and its preparations have a long tradition in self-medication of skin diseases and in cosmetics. The therapeutic use of calendula flowers and ointments goes back at least to Hildegard von Bingen in the 12th Century and has been mentioned in many popular medical books for almost a hundred years.
FLAVEX Naturextrakte
Marigold Flower CO2-to extract (organic), DE-OKO-013, Type No. 018.002
Odor: characteristic
Use: In cosmetics and pharmaceuticals, for treatment of hurts, bruises and inflammations, for wound healing and increasing the granulation, for dry sensitive skin, in face creams, sun lotions, lipsticks, hair shampoos, bath additives.
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  300 mg/kg
Indian Journal of Experimental Biology. Vol. 6, Pg. 232, 1968.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Recommendation for calendula officinalis flower oil CO2 extract flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 70892-20-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 calendula officinalis l. flower oil CO2 extract
Chemidplus: 0070892205
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References:
 calendula officinalis l. flower oil CO2 extract
Canada Domestic Sub. List: 70892-20-5
Pubchem (sid): 135310698
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Other Information:
Wikipedia: View
FAO Doc: BASIC PRINCIPLES OF STEAM DISTILLATION
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 calendula officinalis flower waterFL/FR
 eremophila mitchelli wood oil australiaFR
balsamic
 amyris wood oilFL/FR
 balsam fir oleoresinFL/FR
siam benzoin resinFL/FR
siam benzoin resinoidFL/FR
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
 brachyleana hutchinsii wood oilFR
 callitropsis araucarioides wood oilFR
 cistus leaf oilFR
 conifer acetateFR
 copaifera reticulata extractFL/FR
 croton glabellus bark extractFL/FR
 cyclohexyl benzoateFL/FR
 fir balsam absolute (abies balsamea)FR
 fir needle oil canadaFL/FR
 fir needle oil terpeneless canadaFL/FR
 guaiacyl phenyl acetateFL/FR
 guaiyl butyrateFR
 gurjun balsamFR
 hemlock western oil (tsuga heterophylla) canadaFR
 juniper absoluteFL/FR
 juniper berry absoluteFL/FR
 juniper berry oil CO2 extractFL/FR
 methyl hydrogenated rosinateFR
 myrrh absoluteFL/FR
 myrrh gumFL/FR
 myrrh resinFL/FR
 myrrh resinoidFR
 opoponax absolute (commiphora erythraea var. glabrescens engle)FL/FR
 opoponax resinoid (commiphora erythraea var. glabrescens engle)FR
 peru balsam absoluteFL/FR
scotch pine wood/needles resinoidFR
 pistacia lentiscus gum waterFR
 styrax specialityFR
 tolu balsam resinFL/FR
 valeriana wallichii root oilFR
berry
sec-butyl ethyl etherFL/FR
burnt
 lepidineFL/FR
citrus
 acetaldehyde citronellyl methyl acetalFR
 citrus woody floral fragranceFR
 myrcenyl acetateFL/FR
earthy
(Z)-linalool oxide (furanoid)FL/FR
fir needle
 abies amabilis oil canadaFR
floral
ortho-acetyl-para-cresolFL/FR
 amyl salicylateFL/FR
isoamyl salicylateFL/FR
 benzyl pivalateFL/FR
 butyl tiglateFR
 cananga oilFL/FR
 cananga oil chinaFL/FR
 cassie absoluteFL/FR
 cassie absolute replacerFL/FR
 cassis cyclohexeneFR
 citronellalFL/FR
 cymbopogon validus leaf oilFR
delta-damasconeFL/FR
 dihydro-alpha-iononeFL/FR
 dihydromyrceneFR
2',4'-dimethyl acetophenoneFL/FR
2,4-dimethyl cyclohexyl methyl acetateFR
4-dimethyl iononeFR
2,4-dimethyl-3-cyclohexene-1-methanolFR
 eau de brouts absoluteFR
 elder flower wood specialtyFR
 eucalyptus macarthurii oilFR
 heather fragranceFR
 heliotrope absoluteFR
 herbal pyranFR
 ho leaf oilFR
 ilex paraguariensis oleoresinFL/FR
beta-ionolFL/FR
alpha-iononeFL/FR
(E)-beta-iononeFL/FR
alpha-ionyl acetateFR
isojasmoneFL/FR
(Z)-jasmoneFL/FR
 karo karounde absoluteFR
 lavandin concrete decolorizedFR
 lavandin oilFL/FR
 lavandula angustifolia flower oilFL/FR
 lavender absolute replacerFR
 lavender oilFL/FR
 lavender oil bulgariaFL/FR
 lavender oil franceFL/FR
 lavender oil greeceFL/FR
 lavender oil replacerFR
laevo-linaloolFL/FR
 linalool oxideFL/FR
 melaleuca ericifolia leaf oilFR
alpha-isomethyl ionone (60% min.)FL/FR
alpha-isomethyl ionone (70% min.)FL/FR
alpha-isomethyl ionone (80% min.)FL/FR
2-methyl naphthaleneFL/FR
 mimosa concrete franceFL/FR
 mimosa tenuiflora leaf extractFL/FR
 nonisyl propionateFR
(Z)-beta-ocimeneFL/FR
bitter orangeflower concreteFR
 orris rhizome absolute replacerFR
 pelargonium graveolens flower waterFR
 petitgrain cedrat oilFL/FR
 petitgrain oil terpenesFR
 phenethyl hexanoateFL/FR
isophytolFL/FR
 prenyl salicylateFL/FR
 rose absolute (rosa centifolia) moroccoFL/FR
 rose concrete (rosa centifolia)FR
 sambucus nigra flower oil CO2 extractFR
 styralyl formateFL/FR
 terpinyl isobutyrateFL/FR
 tetrahydrolinalyl acetateFR
 vetiver pentanoneFR
fruity
1,4-diisopropyl-6,8-dioxabicyclo(3.2.1)octaneFR
 fruity butanateFR
 linalool oxide acetatesFL/FR
 marigold absolute (tagetes glandulifera)FR
 octyl propionateFL/FR
 sambucus canadensis fruit absoluteFL/FR
 tropical iononeFL/FR
green
 acetaldehyde di-(Z)-3-hexen-1-yl acetalFL/FR
 acetaldehyde ethyl phenethyl acetalFL/FR
isobutyl benzyl carbinolFL/FR
 butyl heptanoateFL/FR
 galbanum oleoresinFL/FR
 galbanum resinoidFL/FR
isogreen methanoindeneFR
 heptyl formateFL/FR
(Z)-3-hexen-1-yl angelateFR
(E)-2-hexen-1-yl salicylateFR
 marigold pot absoluteFL/FR
para-methyl hydratropaldehydeFL/FR
 valerian rhizome oil CO2 extract chinaFL/FR
herbal
 artemisia vestita wall. leaf oilFR
 calendula officinalis flower extractFR
 cananga fruit oilFR
 canarium luzonicum gumFL/FR
 carrot seed oil (daucus carota ssp. gummifer hook. fil.) spainFR
 chamomile isobutyrateFR
 chrysanthemum ketoneFR
 coriander seed absoluteFL/FR
 freesia heptanolFL/FR
 immortelle flower oilFL/FR
 inula root oilFR
 lavandin flower waterFR
 lavender absolute bulgariaFL/FR
 lavender oil terpenelessFL/FR
 lavender stem oil lithuaniaFR
 marigold absolute (tagetes minuta)FL/FR
 marigold absolute (tagetes patula)FR
 marigold concreteFR
 marigold concrete (tagetes glandulifera) mexicoFR
 marigold oil mexicoFL/FR
 marigold pot concreteFR
 marigold pot flower oilFL/FR
laevo-menthyl propionateFL/FR
 methyl cyclogeranate (Firmenich)FR
 methyl ortho-anisateFL/FR
 myrtle oil moroccoFL/FR
 nonisyl acetateFR
 rosemary absoluteFL/FR
 rosemary oilFL/FR
 rosemary oil africaFL/FR
 rosemary oil moroccoFL/FR
 rosemary oil spainFL/FR
 rosemary oil tunisiaFL/FR
green tea leaf absoluteFL/FR
 valerian rhizome oilFL/FR
 valerian rhizome oil chinaFL/FR
mossy
 moss specialtyFR
musk
 amyris specialtyFR
 ethylene brassylateFL/FR
nutty
 sesame absoluteFL/FR
 sesame absolute CO2 extractFL/FR
pine
 abies sibirica needle extractFR
white pine bark oilFL/FR
 pine specialtyFR
powdery
(E)-alpha-methyl ionone (44-50%)FL/FR
rummy
 rum extractFL/FR
smoky
 boswellia serrata wood tar oilFR
spicy
 cananga leaf oilFR
 carnation absoluteFR
 cinnamomum culilawan bark oilFR
 clove bud oilFL/FR
 elettaria cardamomum seed oil guatemalaFL/FR
isoeugenolFL/FR
 myristica fragrans fruit extractFL/FR
 myristica fragrans seed tinctureFL/FR
 nutmeg absoluteFL/FR
white sassafras oilFL/FR
 spicy carbonateFR
terpenic
 elemi resinoidFL/FR
 pine needle oil dwarfFL/FR
alpha-terpineolFL/FR
 turpentine oilFL/FR
tonka
 tonka undecanoneFR
woody
 agarwood oilFR
 agarwood oil CO2 extractFR
 agarwood specialtyFR
 anthocephalus cadamba oilFR
 bois de rose leaf oil brazilFL/FR
 bulnesia sarmienti extractFR
 cabreuva wood oilFR
 cedarwood oil texas fractionsFR
 chloranthus spicatus absoluteFR
 cistus twig/leaf absoluteFR
 copaiba balsamFL/FR
2-decalinyl acetateFR
 dihydro-beta-ionolFL/FR
alpha-guaieneFL/FR
 homalomena rubescens root oilFR
 kaempferia galanga rhizome oilFL/FR
3-methyl pentyl angelateFR
 sandal cyclohexanolFR
(R)-sandal hexanolFR
 sandal hexanolFR
 sandal octanolFR
 sandalwood oilFL/FR
 sandalwood oil CO2 extractFL/FR
 sandalwood oil west australiaFL/FR
 sandalwood oil west australia (santalum spicatum)FR
 santallFR
 santalum paniculatum wood oilFR
 santalyl acetateFL/FR
 santalyl butyrateFL/FR
 siam wood oilFR
 vetiver oil bourbonFL/FR
 vetiver oil brazilFL/FR
 vetiver oil chinaFL/FR
 vetiver oil indiaFL/FR
 vetiverolFL/FR
(Z)-woody amyleneFR
 zdravetz absoluteFR
 zdravetz oilFL/FR
 
For Flavor
 
No flavor group found for these
 acetaldehyde di-(Z)-3-hexen-1-yl acetalFL/FR
ortho-acetyl-para-cresolFL/FR
 balsam fir oleoresinFL/FR
 benzyl pivalateFL/FR
sec-butyl ethyl etherFL/FR
 calendula officinalis flower waterFL/FR
 cassie absolute replacerFL/FR
 croton glabellus bark extractFL/FR
 cyclohexyl benzoateFL/FR
 dihydro-beta-ionolFL/FR
2',4'-dimethyl acetophenoneFL/FR
 fir needle oil canadaFL/FR
alpha-guaieneFL/FR
 ilex paraguariensis oleoresinFL/FR
 juniper absoluteFL/FR
(Z)-linalool oxide (furanoid)FL/FR
 linalool oxide acetatesFL/FR
 marigold pot flower oilFL/FR
laevo-menthyl propionateFL/FR
(E)-alpha-methyl ionone (44-50%)FL/FR
alpha-isomethyl ionone (60% min.)FL/FR
 methyl ortho-anisateFL/FR
 myrtle oil moroccoFL/FR
white pine bark oilFL/FR
 sandalwood oil west australiaFL/FR
 santalyl butyrateFL/FR
white sassafras oilFL/FR
 styralyl formateFL/FR
 terpinyl isobutyrateFL/FR
 turpentine oilFL/FR
 zdravetz oilFL/FR
amber
isobutyl benzyl carbinolFL/FR
aromatic
 amyl salicylateFL/FR
balsamic
siam benzoin resinFL/FR
siam benzoin resinoidFL/FR
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
 copaifera reticulata extractFL/FR
 fir needle oil terpeneless canadaFL/FR
 juniper berry absoluteFL/FR
 juniper berry oil CO2 extractFL/FR
 myrrh absoluteFL/FR
 myrrh gumFL/FR
 myrrh resinFL/FR
 opoponax absolute (commiphora erythraea var. glabrescens engle)FL/FR
 peru balsam absoluteFL/FR
 tolu balsam resinFL/FR
berry
 dihydro-alpha-iononeFL/FR
camphoreous
 kaempferia galanga rhizome oilFL/FR
 rosemary oil tunisiaFL/FR
citrus
 freesia heptanolFL/FR
laevo-linaloolFL/FR
 myrcenyl acetateFL/FR
 petitgrain cedrat oilFL/FR
alpha-terpineolFL/FR
estery
 octyl propionateFL/FR
fatty
 heptyl formateFL/FR
floral
 bois de rose leaf oil brazilFL/FR
 cananga oilFL/FR
 cananga oil chinaFL/FR
 citronellalFL/FR
beta-ionolFL/FR
alpha-iononeFL/FR
 lepidineFL/FR
alpha-isomethyl ionone (70% min.)FL/FR
alpha-isomethyl ionone (80% min.)FL/FR
 mimosa concrete franceFL/FR
 mimosa tenuiflora leaf extractFL/FR
 rose absolute (rosa centifolia) moroccoFL/FR
 tropical iononeFL/FR
fruity
 butyl heptanoateFL/FR
 sambucus canadensis fruit absoluteFL/FR
 valerian rhizome oilFL/FR
 valerian rhizome oil chinaFL/FR
 valerian rhizome oil CO2 extract chinaFL/FR
green
 acetaldehyde ethyl phenethyl acetalFL/FR
isoamyl salicylateFL/FR
 canarium luzonicum gumFL/FR
 elemi resinoidFL/FR
 galbanum oleoresinFL/FR
 galbanum resinoidFL/FR
isojasmoneFL/FR
 linalool oxideFL/FR
 marigold pot absoluteFL/FR
para-methyl hydratropaldehydeFL/FR
(Z)-beta-ocimeneFL/FR
herbal
 coriander seed absoluteFL/FR
 immortelle flower oilFL/FR
 lavandin oilFL/FR
 lavandula angustifolia flower oilFL/FR
 lavender absolute bulgariaFL/FR
 lavender oilFL/FR
 lavender oil bulgariaFL/FR
 lavender oil franceFL/FR
 lavender oil greeceFL/FR
 lavender oil terpenelessFL/FR
 marigold absolute (tagetes minuta)FL/FR
 marigold oil mexicoFL/FR
 prenyl salicylateFL/FR
 rosemary absoluteFL/FR
 rosemary oilFL/FR
 rosemary oil africaFL/FR
 rosemary oil moroccoFL/FR
 rosemary oil spainFL/FR
musk
 ethylene brassylateFL/FR
nutty
 sesame absoluteFL/FR
 sesame absolute CO2 extractFL/FR
oily
2-methyl naphthaleneFL/FR
isophytolFL/FR
phenolic
 guaiacyl phenyl acetateFL/FR
pine
 pine needle oil dwarfFL/FR
rummy
 rum extractFL/FR
spicy
 cassie absoluteFL/FR
 clove bud oilFL/FR
 elettaria cardamomum seed oil guatemalaFL/FR
isoeugenolFL/FR
 myristica fragrans fruit extractFL/FR
 myristica fragrans seed tinctureFL/FR
 nutmeg absoluteFL/FR
tea
green tea leaf absoluteFL/FR
waxy
 phenethyl hexanoateFL/FR
woody
 amyris wood oilFL/FR
 copaiba balsamFL/FR
delta-damasconeFL/FR
(E)-beta-iononeFL/FR
(Z)-jasmoneFL/FR
 sandalwood oilFL/FR
 sandalwood oil CO2 extractFL/FR
 santalyl acetateFL/FR
 vetiver oil bourbonFL/FR
 vetiver oil brazilFL/FR
 vetiver oil chinaFL/FR
 vetiver oil indiaFL/FR
 vetiverolFL/FR
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 marigold pot marigold flower
Search Trop  Picture
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Synonyms:
 calendula flower oil CO2 extract
garden marigold oil CO2 extract
 marigold pot flower oil CO2 extract
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Articles:
PubMed: Extracts from Calendula officinalis Offer in Vitro Protection Against H2 O2 Induced Oxidative Stress Cell Killing of Human Skin Cells.
PubMed: Protective Effect of Calendula officinalis L. Flowers Against Monosodium Glutamate Induced Oxidative Stress and Excitotoxic Brain Damage in Rats.
PubMed: Protective effect of Calendula officinalis Linn. flowers against 3-nitropropionic acid induced experimental Huntington's disease in rats.
PubMed: Assessment of In vitro Sun Protection Factor of Calendula Officinalis L. (Asteraceae) Essential Oil Formulation.
PubMed: Inhibition of metastasis of B16F-10 melanoma cells in C57BL/6 mice by an extract of Calendula officinalis L flowers.
PubMed: Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients.
PubMed: Wound healing activity of flower extract of Calendula officinalis.
PubMed: Hepato and reno protective action of Calendula officinalis L. flower extract.
PubMed: Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action.
PubMed: Application of the threshold of toxicological concern approach for the safety evaluation of calendula flower (Calendula officinalis) petals and extracts used in cosmetic and personal care products.
PubMed: Use of heteroduplex mobility assay for identification and differentiation of phytoplasmas in the aster yellows group and the clover proliferation group.
PubMed: Effect of Calendula officinalis Flower Extract on Acute Phase Proteins, Antioxidant Defense Mechanism and Granuloma Formation During Thermal Burns.
PubMed: The comparison of in vivo antigenotoxic and antioxidative capacity of two propylene glycol extracts of Calendula officinalis (marigold) and vitamin E in young growing pigs.
PubMed: Studies of selected plant raw materials as alternative sources of triterpenes of oleanolic and ursolic acid types.
PubMed: A dual and opposite effect of Calendula officinalis flower extract: chemoprotector and promoter in a rat hepatocarcinogenesis model.
PubMed: Investigation of genotoxic and antigenotoxic activities of Melampodium divaricatum in Salmonella typhimurium.
PubMed: Preparative purification of the major anti-inflammatory triterpenoid esters from Marigold (Calendula officinalis).
PubMed: HPLC study on the carotenoid composition of Calendula products.
PubMed: Genotoxic and anti-genotoxic properties of Calendula officinalis extracts in rat liver cell cultures treated with diethylnitrosamine.
PubMed: Morphogenetic variability of faradiol monoesters in marigold Calendula officinalis L.
PubMed: Anti-oedematous activities of the main triterpendiol esters of marigold (Calendula officinalis L.).
PubMed: The effect of vitamin E on flower initiation in Calendula officinalis L. grown in short day.
PubMed: Studies in carotenogenesis. 13. The carotenoids of the flower petals of Calendula officinalis.
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