valeriana officinalis rhizome extract
extract of the rhizomes of the valerian, valeriana officinalis l., valerianaceae
 
Notes:
None found
  • Horner International
    • Horner International
      The finest extracts in the world
      Horner International supplies the finest natural extracts and flavors to a world-wide customer base.
      Horner International supplies the finest natural extracts and flavors to a world-wide customer base. Our new North American production facility in Durham, North Carolina features multiple production lines for extraction and concentration via proprietary technology. A diverse team with decades of experience and know-how, we apply our skills to some of the most challenging products found in nature. We are committed to treat our customers in the way we wish to be treated. We believe that natural products play a positive, sustainable role in a future that is good for farmers, communities, and our customers. Our goal is to produce the best-tasting, most consistent natural extracts and flavors in the world.
      US Email: Lisa Ramraj
      Voice: +1 919 787 3112
      Fax: +1 919 787 4272
      US Voice: +1 919 787 3112 ext. 112
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      Custom Manufacturing
      Product(s):
      Valerian Fluid Extract
      Valerian Spray-Dried Powder Extract
       
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Name: valeriana officinalis l. rhizome extract
CAS Number: 8057-49-6 
ECHA EC Number: 232-501-7
Wisconsin Invasive Non-native plant species
Category: cosmetic, flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 3099 valerian rhizome extract
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):8057-49-6 ; VALERIAN ROOT, EXTRACT (VALERIANA OFFICINALIS L.)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor Type: fruity
 
Odor Strength: medium
 
 valerian root  
Odor Description:
at 100.00 %. 
valerian root
 
 
Flavor Type: fruity
 
 valerian root  
Taste Description:
valerian root
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
Bristol Botanicals
Valerian root fluid extract Valeriana officinalis 1:1 45%
Changsha Organic Herb
valerian extract
Horner International
Valerian Fluid Extract
Horner International
Valerian Spray-Dried Powder Extract
Xi'an Greena Biotech
Valerian Extract
Odor: characteristic
Use: Valerian is well known for its sedative qualities and its ability to relax the central nervous system and anti-anxiety capabilities.Valerian has been used in Unani, Ayurvedic, and traditional Chinese Medicinal for centuries.Valerian has been used for its sedative properties many years in France, Germany,and Switzerland.The valerian root contains compounds including valeric acid, valeranone,hydroxy valerenic acid,valerianine,valepoitriate,maali alcohol,isovaltrate,patchouli alcohol and other active ingredients.
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mammal (species unspecified) LD50  975 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 403, 1988.

oral-mammal (species unspecified) LD50  2250 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 403, 1988.

intraperitoneal-mouse LD50  3300 mg/kg
KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Journal of Pharmaceutical Sciences. Vol. 50, Pg. 240, 1961.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic, flavor and fragrance agents
Wisconsin Invasive Non-native plant species
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -69.00000
beverages(nonalcoholic): -25.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -24.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -35.00000
fruit ices: -35.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -65.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
ClinicalTrials.gov: search
Daily Med: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 valeriana officinalis l. rhizome extract
Chemidplus: 0008057496
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References:
 valeriana officinalis l. rhizome extract
Pubchem (sid): 135331255
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
FDA Listing of Food Additive Status: View
MedlinePlusSupp: View
Wikipedia: View
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Potential Blenders and core components note
 
For Odor
balsamic
balsamic
 valerian rhizome absoluteFL/FR
 valeriana wallichii root oilFR
dirty
3,3-dimethyl-5- and 6-isopropyl bicyclo(2.2.2)-5,7-octadiene-2-one 
fruity
 valerian rhizome essenceFL/FR
 valeriana officinalis rhizome tinctureFL/FR
 valeriana officinalis rhizome/root extractFL/FR
 valeriana officinalis root extractFL/FR
green
3-hexenyl isovalerateFL/FR
1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)oct-5-ene 
 valerian rhizome oil CO2 extract chinaFL/FR
herbal
(-)-bornyl isovalerateFL/FR
white cognac oilFL/FR
 hop absoluteFL/FR
 valerian rhizome oilFL/FR
 valerian rhizome oil chinaFL/FR
woody
isobornyl isovalerateFL/FR
 spikenard oilFL/FR
 spikenard oil CO2 extractFL/FR
 
For Flavor
 
No flavor group found for these
(-)-bornyl isovalerateFL/FR
3,3-dimethyl-5- and 6-isopropyl bicyclo(2.2.2)-5,7-octadiene-2-one 
 menthyl valerateFL
 spikenard oilFL/FR
 spikenard oil CO2 extractFL/FR
1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)oct-5-ene 
fruity
 valerian rhizome absoluteFL/FR
 valerian rhizome distillatesFL
 valerian rhizome essenceFL/FR
 valerian rhizome oilFL/FR
 valerian rhizome oil chinaFL/FR
 valerian rhizome oil CO2 extract chinaFL/FR
 valeriana officinalis rhizome tinctureFL/FR
 valeriana officinalis rhizome/root extractFL/FR
 valeriana officinalis root extractFL/FR
fusel
white cognac oilFL/FR
green
3-hexenyl isovalerateFL/FR
herbal
 hop absoluteFL/FR
woody
isobornyl isovalerateFL/FR
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 valerian rhizome
Search Trop  Picture
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Synonyms:
 extract of the rhizomes of the valerian, valeriana officinalis l., valerianaceae
 valerian fluid extract
 valerian rhizome extract
 valerian root extract (so called)
 valerian spray-dried powder extract
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Articles:
PubMed: Antioxidant effect and study of bioactive components of Valeriana sisymbriifolia and Nardostachys jatamansii in comparison to Valeriana officinalis.
PubMed: Isolation of 9-hydroxy-10E,12Z-octadecadienoic acid, an inhibitor of fat accumulation from Valeriana fauriei.
PubMed: Antidepressant effect of Valeriana wallichii patchouli alcohol chemotype in mice: Behavioural and biochemical evidence.
PubMed: Valeriana jatamansi partially reverses liver cirrhosis and tissue hyperproliferative response in rat.
PubMed: Chemical analysis and biological activity of the essential oils of two valerianaceous species from China: Nardostachys chinensis and Valeriana officinalis.
PubMed: Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker.
PubMed: Terpenoid content of Valeriana wallichii extracts and antidepressant-like response profiles.
PubMed: Root colonization by symbiotic arbuscular mycorrhizal fungi increases sesquiterpenic acid concentrations in Valeriana officinalis L.
PubMed: Transport of a GABAA receptor modulator and its derivatives from Valeriana officinalis L. s. l. across an in vitro cell culture model of the blood-brain barrier.
PubMed: [Studies on chemical constituents of Valeriana officinalis].
PubMed: [Study on quality specification of Rhizoma et Radix Valeriana Jatamansi].
PubMed: Effects of aqueous, methanolic and chloroform extracts of rhizome and aerial parts of Valeriana officinalis L. on naloxone-induced jumping in morphine-dependent mice.
PubMed: Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation.
PubMed: Polysomnographic evaluation of the hypnotic effect of Valeriana edulis standardized extract in patients suffering from insomnia.
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