(E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide
rubescenamine
 
Notes:
None found
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CAS Number: 125187-30-6Picture of molecule3D/inchi
FDA UNII: NT6KZD17F5
Nikkaji Web: J3.469.403F
XlogP3: 2.60 (est)
Molecular Weight: 355.39037000
Formula: C20 H21 N O5
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor enhancers, umami taste enhancer
 
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JECFA Food Flavoring: 2227  (E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide
FEMA Number: 4773 (E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide
FDA:No longer provide for the use of these seven synthetic flavoring substances
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Physical Properties:
Appearance: white powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 153.00 to  154.00 °C. @ 760.00 mm Hg
Boiling Point: 593.31 °C. @ 760.00 mm Hg (est)
Flash Point: 595.00 °F. TCC ( 312.60 °C. ) (est)
logP (o/w): 3.204 (est)
Soluble in:
 water, 10.77 mg/L @ 25 °C (est)
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Organoleptic Properties:
Odor Description:
savory
 
 
Flavor Type: savory
 
 savory  
Taste Description:
savory
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the CSA
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor enhancers, umami taste enhancer
Recommendation for (E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 26
Click here to view publication 26
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 0.200002.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: 2.000009.00000
chewing gum: --
condiments / relishes: 2.0000015.00000
confectionery froastings: --
egg products: 4.0000015.00000
fats / oils: 2.0000012.00000
fish products: 2.0000012.00000
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 2.0000015.00000
hard candy: --
imitation dairy: --
instant coffee / tea: 0.200002.50000
jams / jellies: --
meat products: 2.0000012.00000
milk products: --
nut products: --
other grains: --
poultry: 2.0000012.00000
processed fruits: --
processed vegetables: 2.0000012.00000
reconstituted vegetables: --
seasonings / flavors: 10.0000030.00000
snack foods: 5.0000030.00000
soft candy: --
soups: 2.0000015.00000
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 18159637
National Institute of Allergy and Infectious Diseases: Data
 (2E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide
Chemidplus: 0125187306
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References:
 (2E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 18159637
Pubchem (cas): 125187-30-6
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
For Odor
alliaceous
alliaceous
 dibutyl sulfideFL/FR
 dimethyl trisulfideFL/FR
 ferula assa-foetida gum oilFL/FR
 furfuryl mercaptanFL/FR
1-octen-3-olFL/FR
fatty
3-decen-2-oneFL/FR
green
 cortex pyridineFL/FR
herbal
 carum carvi fruit oilFL/FR
 trigonella foenum-graecum seed extractFL/FR
medicinal
summer savory oilFL/FR
moldy
 strawberry furanone methyl etherFL/FR
phenolic
ortho-guaiacolFL/FR
spicy
 eugenolFL/FR
 furfuryl thioacetateFL/FR
2-methyl 5-(methyl thio) furanFL/FR
 methyl mercaptanFL/FR
3-thiohexanolFL/FR
 
For Flavor
 
alliaceous
 allyl mercaptanFL
 dimethyl trisulfideFL/FR
 ferula assa-foetida gum oilFL/FR
3-mercapto-2-pentanoneFL
bready
 trigonella foenum-graecum seed extractFL/FR
coffee
 furfuryl mercaptanFL/FR
earthy
 difurfuryl sulfideFL
 mushroom flavorFL
fatty
2,4-octadien-1-olFL
fishy
4,5-dimethyl thiazoleFL
fruity
 acerola fruit distillatesFL
garlic
 allyl methyl sulfideFL
 garlic distillatesFL
 garlic flavorFL
green
 cortex pyridineFL/FR
3-decen-2-oneFL/FR
 dibutyl sulfideFL/FR
herbal
 caraway flavorFL
 carum carvi fruit oilFL/FR
meaty
 brown flavorFL
 chicken broth flavorFL
roast chicken flavorFL
grilled chicken flavorFL
 chicken flavorFL
 chicken keyFL
 chicken soup stock flavorFL
(R,S)-2-mercapto-3-butanolFL
3-mercapto-3-methyl butanolFL
12-methyl tridecanalFL
bis(2-methyl-3-furyl) disulfideFL
2-methyl-3-tetrahydrofuran thiolFL
 pyrazinyl ethane thiolFL
2-pyridinyl methane thiolFL
medicinal
summer savory oilFL/FR
summer savory oleoresinFL
metallic
2,5-dihydroxy-1,4-dithianeFL
moldy
 strawberry furanone methyl etherFL/FR
mushroom
1-octen-3-olFL/FR
musty
2-methyl 5-(methyl thio) furanFL/FR
nutty
 nutty thiazoleFL
onion
 durian flavorFL
 furfuryl isopropyl sulfideFL
 methionolFL
roasted
 furfuryl thioacetateFL/FR
salty
1-(2-hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-oneFL
savory
5'-adenylic acid sodium saltFL
(E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamideFL
 disodium adenosine 5'-phosphateFL
2,4,6-triethyl tetrahydro-1,3,5-dithiazineFL
seafood
 clam extractFL
 clam flavorFL
smoky
 prosopis juliflora wood extractFL
spicy
 eugenolFL/FR
winter savory oilFL
winter savory oleoresinFL
sulfurous
 butyl mercaptanFL
 furfuryl thiopropionateFL
3-mercapto-2-methyl pentanalFL
 methyl 2-(methyl thio) butyrateFL
 methyl 2-methyl-3-furyl disulfideFL
 methyl mercaptanFL/FR
 methyl thiomethyl butyrateFL
3-methyl-2-butane thiolFL
 roasted butanolFL
3-thiohexanolFL/FR
tropical
 acerola flavorFL
3-mercaptohexyl butyrateFL
woody
ortho-guaiacolFL/FR
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 zanrhoxylum rubescens
Search Trop  Picture
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Synonyms:
(E)-N-[2-(benzo[d][1,3]dioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide
(2E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide
 rubescenamine
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