Category: sweeteners, flavor enhancers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white powder (est) |
Assay: | 95.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Boiling Point: | 784.00 to 785.00 °C. @ 760.00 mm Hg (est)
|
Flash Point: | 559.00 °F. TCC ( 292.50 °C. ) (est)
|
logP (o/w): | -2.941 (est) |
Soluble in: |
| water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
|
|
Flavor Type: sweet |
|
| sweet |
|
Odor and/or flavor descriptions from others (if found). |
|
|
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
|
Dermal Toxicity: |
Not determined
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | sweeteners, flavor enhancers |
Recommendation for isomaltulose usage levels up to: | | not for fragrance use.
|
|
Safety References:
EPI System: | View |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 83686 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| (3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one |
Chemidplus: | 0013718940 |
References:
| (3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 83686 |
Pubchem (sid): | 135041561 |
Other Information:
Potential Blenders and core components note
|
For Odor |
alcoholic |
alcoholic |
| fusel oil | FL/FR |
animal |
| methyl (E)-2-octenoate | FL/FR |
anise |
star | anise seed oil terpeneless | FL/FR |
anisic |
para- | acetanisole | FL/FR |
| ethyl para-anisate | FL/FR |
balsamic |
| benzyl salicylate | FL/FR |
| ethyl cinnamate | FL/FR |
dextro- | fenchone | FL/FR |
| guaiacyl phenyl acetate | FL/FR |
| hexyl benzoate | FL/FR |
bready |
| furfural | FL/FR |
buttery |
| acetoin | FL/FR |
| caramel furanone solution | FL/FR |
| caramel pentadione | FL/FR |
| coffee dione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
| ethyl cyclopentenolone | FL/FR |
| ethyl furaneol | FL/FR |
| ethyl maltol | FL/FR |
| levulinic acid | FL/FR |
| maltol | FL/FR |
| maltyl isobutyrate | FL/FR |
| maltyl propionate | FL/FR |
| maple furanone | FL/FR |
5- | methyl furfural | FL/FR |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| strawberry furanone acetate | FL/FR |
| strawberry furanone solution | FL/FR |
cheesy |
iso | valeric acid | FL/FR |
chemical |
iso | butyl formate | FL/FR |
| propyl propionate | FL/FR |
chocolate |
iso | amyl phenyl acetate | FL/FR |
| cocoa pentenal | FL/FR |
citrus |
2- | ethyl-1-hexanol | FL/FR |
| lime essence oil | FL/FR |
dextro- | limonene | FL/FR |
alpha- | terpinyl methyl ether | FL/FR |
delta- | octalactone | FL/FR |
creamy |
3- | heptyl dihydro-5-methyl-2(3H)-furanone | FL/FR |
para- | vanillic acid | FL/FR |
para- | vanillyl alcohol | FL/FR |
| veratraldehyde | FL/FR |
dry |
3,4- | xylenol | FL/FR |
earthy |
| methyl 3-hexenoate | FL/FR |
ethereal |
| ethyl acetate | FL/FR |
| ethyl formate | FL/FR |
| ethyl pyruvate | FL/FR |
iso | propyl formate | FL/FR |
fatty |
(E)-2- | octenal | FL/FR |
(E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
floral |
| acetophenone | FL/FR |
| benzyl acetate | FL/FR |
| benzyl isobutyrate | FL/FR |
| citronellyl anthranilate | FL/FR |
| citronellyl phenyl acetate | FL/FR |
| ethyl phenyl acetate | FL/FR |
| geranyl isobutyrate | FL/FR |
| heliotropyl acetone | FL/FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hexyl lactate | FL/FR |
| hydroxycitronellal | FL/FR |
| hydroxycitronellol | FL/FR |
alpha- | ionol | FL/FR |
para- | methyl acetophenone | FL/FR |
beta- | naphthyl methyl ketone | FL/FR |
| nonanol | FL/FR |
| phenethyl alcohol | FL/FR |
| phenethyl propionate | FL/FR |
4- | phenyl-3-buten-2-ol | FL/FR |
iso | propyl phenyl acetate | FL/FR |
| rhodinyl phenyl acetate | FL/FR |
| rose butanoate | FL/FR |
| rose oil (rosa damascena) russia | FL/FR |
| rose oil (rosa damascena) turkey | FL/FR |
| terpinyl valerate | FL/FR |
| tuberose absolute (from pommade) | FL/FR |
fruity |
| allyl hexanoate | FL/FR |
iso | butyl 2-butenoate | FL/FR |
iso | butyl acetoacetate | FL/FR |
iso | butyl anthranilate | FL/FR |
| butyl butyrate | FL/FR |
iso | butyl butyrate | FL/FR |
iso | butyl isovalerate | FL/FR |
| butyl isovalerate | FL/FR |
| ethyl 3-(2-furyl) propanoate | FL/FR |
| ethyl 3-hexenoate | FL/FR |
| ethyl 3-hydroxyhexanoate | FL/FR |
| ethyl benzoyl acetate | FL/FR |
| ethyl butyrate | FL/FR |
| ethyl isovalerate | FL/FR |
| ethyl lactate | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
| ethyl propionate | FL/FR |
(E,E)- | ethyl sorbate | FL/FR |
| ethyl valerate | FL/FR |
2- | hexen-1-ol | FL/FR |
| hexyl acetate | FL/FR |
| linalyl isobutyrate | FL/FR |
| menthyl isovalerate | FL/FR |
| methyl 3-nonenoate | FL/FR |
| methyl anthranilate | FL/FR |
2- | methyl butyl acetate | FL/FR |
| methyl heptanoate | FL/FR |
| methyl isobutyrate | FL/FR |
| methyl valerate | FL/FR |
| neryl isobutyrate | FL/FR |
| octyl butyrate | FL/FR |
| octyl propionate | FL/FR |
2- | pentanone | FL/FR |
| pineapple hydroxyhexanoate | FL/FR |
| prenyl acetate | FL/FR |
iso | propyl 2-methyl butyrate | FL/FR |
| propyl butyrate | FL/FR |
iso | propyl butyrate | FL/FR |
| propyl heptanoate | FL/FR |
| propyl hexanoate | FL/FR |
| propyl isobutyrate | FL/FR |
iso | propyl octanoate | FL/FR |
| strawberry glycidate 1 (aldehyde C-16 (so-called)) | FL/FR |
| strawberry glycidate 2 | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
para- | tolualdehyde | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
| tropical ionone | FL/FR |
| vanilla carboxylate | FL/FR |
green |
| cucumber essence | FL/FR |
(Z)-4- | hepten-1-ol | FL/FR |
| hexyl isobutyrate | FL/FR |
| hexyl phenyl acetate | FL/FR |
(E,Z)-3,6- | nonadien-1-yl acetate | FL/FR |
(E)-2- | octen-1-ol | FL/FR |
2- | octen-1-ol | FL/FR |
| phenethyl tiglate | FL/FR |
| terpinyl propionate | FL/FR |
herbal |
| anethum graveolens herb tincture | FL/FR |
| clary sage absolute | FL/FR |
| linalyl isovalerate | FL/FR |
| linalyl octanoate | FL/FR |
| lovage tincture | FL/FR |
| perillaldehyde | FL/FR |
3- | propylidene phthalide | FL/FR |
honey |
| methyl phenyl acetate | FL/FR |
| propyl phenyl acetate | FL/FR |
licorice |
(E)- | anethol | FL/FR |
medicinal |
2,6- | xylenol | FL/FR |
minty |
| ethyl benzoate | FL/FR |
| ethyl salicylate | FL/FR |
| methyl salicylate | FL/FR |
| peppermint oil america | FL/FR |
| peppermint oil idaho | FL/FR |
musk |
| ethylene brassylate | FL/FR |
musty |
ketoiso | phorone | FL/FR |
iso | butyl angelate | FL/FR |
4- | ethyl guaiacol | FL/FR |
| eugenol | FL/FR |
iso | eugenol | FL/FR |
iso | eugenyl acetate | FL/FR |
iso | eugenyl phenyl acetate | FL/FR |
para- | methoxycinnamaldehyde | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl heptadienone | FL/FR |
alpha- | methyl-(E)-cinnamaldehyde | FL/FR |
(E)- | propyl 2-furan acrylate | FL/FR |
(E)- | tiglic acid | FL/FR |
| vanilla bean absolute (vanilla spp.) | FL/FR |
| vanilla oleoresin bali | FL/FR |
| vanilla resinoid | FL/FR |
| vanilla tahitensis fruit extract | FL/FR |
tonka |
| mint lactone | FL/FR |
| octahydrocoumarin | FL/FR |
tropical |
| genet absolute | FL/FR |
| ethyl vanillin | FL/FR |
| ethyl vanillin propylene glycol acetal | FL/FR |
| propenyl guaethol | FL/FR |
| vanilla aromatica fruit extract | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanilla oleoresin bourbon | FL/FR |
| vanillin | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
| vanillyl acetate | FL/FR |
| vanillyl isobutyrate | FL/FR |
| vanillylidene acetone | FL/FR |
waxy |
| ethyl decanoate | FL/FR |
| ethyl myristate | FL/FR |
| ethyl octanoate | FL/FR |
| nonanoic acid | FL/FR |
1- | undecanol | FL/FR |
woody |
2- | methoxy-4-vinyl phenol | FL/FR |
|
For Flavor |
|
acidic |
(E)-2- | hexenoic acid | FL |
| levulinic acid | FL/FR |
aldehydic |
1- | undecanol | FL/FR |
anise |
(E)- | anethol | FL/FR |
star | anise seed oil terpeneless | FL/FR |
| ethyl para-anisate | FL/FR |
anisic |
para- | acetanisole | FL/FR |
balsamic |
| benzyl salicylate | FL/FR |
| ethyl cinnamate | FL/FR |
| vanillylidene acetone | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
bitter |
(E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
brown |
| furfural | FL/FR |
5- | methyl furfural | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
(E)- | tiglic acid | FL/FR |
burnt |
| furfuryl alcohol | FL |
2,6- | xylenol | FL/FR |
caramellic |
| caramel furanone | FL |
| caramel furanone solution | FL/FR |
| caramel pentadione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
| ethyl furaneol | FL/FR |
| ethyl maltol | FL/FR |
| lucuma flavor | FL |
| maltol | FL/FR |
| maltyl propionate | FL/FR |
| maple distillates | FL |
| maple furanone | FL/FR |
3- | methyl butyl 2-furyl butyrate | FL |
| pyruvaldehyde | FL |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| strawberry furanone acetate | FL/FR |
| strawberry furanone solution | FL/FR |
cheesy |
| ammonium isovalerate 30% in pg | FL |
iso | valeric acid | FL/FR |
cherry |
para- | methoxycinnamaldehyde | FL/FR |
chocolate |
bittersweet | chocolate flavor | FL |
citrus |
| lime essence oil | FL/FR |
dextro- | limonene | FL/FR |
ketoiso | phorone | FL/FR |
coconut |
| massoia bark oil CO2 extract | FL |
| octahydrocoumarin | FL/FR |
delta- | octalactone | FL/FR |
coffee |
| coffee dione | FL/FR |
cooling |
dextro- | fenchone | FL/FR |
| peppermint oil america | FL/FR |
creamy |
| acetoin | FL/FR |
| divanillin | FL |
para- | methyl acetophenone | FL/FR |
| mint lactone | FL/FR |
para- | vanillic acid | FL/FR |
para- | vanillyl alcohol | FL/FR |
| veratraldehyde | FL/FR |
estery |
| octyl propionate | FL/FR |
ethereal |
| ethyl acetate | FL/FR |
| ethyl formate | FL/FR |
| methyl isobutyrate | FL/FR |
fatty |
2- | ethyl-1-hexanol | FL/FR |
| nonanoic acid | FL/FR |
2- | octen-1-ol | FL/FR |
(E)-2- | octen-1-ol | FL/FR |
(E)-2- | octenal | FL/FR |
floral |
2- | acetyl-5-methyl thiophene | FL |
iso | amyl phenyl acetate | FL/FR |
| citronellyl phenyl acetate | FL/FR |
| cocoa pentenal | FL/FR |
| geranyl isobutyrate | FL/FR |
| linalyl isobutyrate | FL/FR |
| methyl phenyl acetate | FL/FR |
beta- | naphthyl methyl ketone | FL/FR |
| phenethyl alcohol | FL/FR |
| phenethyl propionate | FL/FR |
| rose oil (rosa damascena) russia | FL/FR |
| rose oil (rosa damascena) turkey | FL/FR |
| tropical ionone | FL/FR |
| tuberose absolute (from pommade) | FL/FR |
fruity |
| allyl hexanoate | FL/FR |
| benzyl acetate | FL/FR |
| benzyl isobutyrate | FL/FR |
iso | butyl acetoacetate | FL/FR |
iso | butyl anthranilate | FL/FR |
iso | butyl butyrate | FL/FR |
| butyl butyrate | FL/FR |
| butyl isovalerate | FL/FR |
| citronellyl anthranilate | FL/FR |
(E)-2- | decenoic acid | FL |
| ethyl 3-(2-furyl) propanoate | FL/FR |
| ethyl 3-hexenoate | FL/FR |
| ethyl 3-hydroxyhexanoate | FL/FR |
| ethyl 3-oxohexanoate | FL |
| ethyl benzoyl acetate | FL/FR |
| ethyl butyrate | FL/FR |
| ethyl isovalerate | FL/FR |
| ethyl lactate | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
| ethyl propionate | FL/FR |
(E,E)- | ethyl sorbate | FL/FR |
| ethyl valerate | FL/FR |
| furfuryl valerate | FL |
2- | furyl pentyl ketone | FL |
| fusel oil | FL/FR |
3- | heptyl dihydro-5-methyl-2(3H)-furanone | FL/FR |
2- | hexen-1-ol | FL/FR |
| hexyl acetate | FL/FR |
| hexyl lactate | FL/FR |
| hexyl phenyl acetate | FL/FR |
| linalyl isovalerate | FL/FR |
| linalyl octanoate | FL/FR |
| menthyl isovalerate | FL/FR |
| methyl (E)-2-octenoate | FL/FR |
| methyl (E)-3-nonenoate | FL |
| methyl 3-hexenoate | FL/FR |
| methyl 3-nonenoate | FL/FR |
| methyl anthranilate | FL/FR |
2- | methyl butyl acetate | FL/FR |
| methyl heptanoate | FL/FR |
(E,E)- | methyl sorbate | FL |
| methyl valerate | FL/FR |
| neryl isobutyrate | FL/FR |
2- | pentanone | FL/FR |
| pineapple hydroxyhexanoate | FL/FR |
| prenyl acetate | FL/FR |
(E)- | propyl 2-furan acrylate | FL/FR |
iso | propyl 2-methyl butyrate | FL/FR |
| propyl butyrate | FL/FR |
iso | propyl butyrate | FL/FR |
iso | propyl formate | FL/FR |
| propyl hexanoate | FL/FR |
| propyl isobutyrate | FL/FR |
iso | propyl octanoate | FL/FR |
| rose butanoate | FL/FR |
| strawberry glycidate 1 (aldehyde C-16 (so-called)) | FL/FR |
| strawberry glycidate 2 | FL/FR |
| terpinyl valerate | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
| vanilla carboxylate | FL/FR |
green |
| anethum graveolens herb tincture | FL/FR |
iso | butyl 2-butenoate | FL/FR |
iso | butyl angelate | FL/FR |
iso | butyl isovalerate | FL/FR |
| clary sage absolute | FL/FR |
| cucumber essence | FL/FR |
2- | ethyl butyraldehyde | FL |
(Z)-4- | hepten-1-ol | FL/FR |
(E)-2- | heptenal | FL |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
| hexyl benzoate | FL/FR |
| hexyl isobutyrate | FL/FR |
| methyl heptadienone | FL/FR |
(E,Z)-3,6- | nonadien-1-yl acetate | FL/FR |
| phenethyl tiglate | FL/FR |
3- | propylidene phthalide | FL/FR |
| terpinyl propionate | FL/FR |
hay |
| genet absolute | FL/FR |
herbal |
| lovage tincture | FL/FR |
honey |
| ethyl phenyl acetate | FL/FR |
dehydrated and ground | honey | FL |
| honey flavor | FL |
| propyl phenyl acetate | FL/FR |
iso | propyl phenyl acetate | FL/FR |
jammy |
| ethyl cyclopentenolone | FL/FR |
| maltyl isobutyrate | FL/FR |
medicinal |
| ethyl benzoate | FL/FR |
minty |
| ethyl salicylate | FL/FR |
| methyl salicylate | FL/FR |
| peppermint oil idaho | FL/FR |
molasses |
| molasses blackstrap | FL |
mushroom |
| methional diethyl acetal | FL |
musk |
| ethylene brassylate | FL/FR |
phenolic |
| guaiacyl phenyl acetate | FL/FR |
potato |
sweet | potato flavor | FL |
powdery |
| acetophenone | FL/FR |
| hydroxycitronellol | FL/FR |
praline |
| praline flavor | FL |
rummy |
iso | butyl formate | FL/FR |
| ethyl pyruvate | FL/FR |
salty |
1-(2- | hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-one | FL |
smoky |
2- | methoxy-4-vinyl phenol | FL/FR |
3,4- | xylenol | FL/FR |
spicy |
iso | eugenol | FL/FR |
| eugenol | FL/FR |
iso | eugenyl acetate | FL/FR |
iso | eugenyl phenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
alpha- | methyl-(E)-cinnamaldehyde | FL/FR |
| perillaldehyde | FL/FR |
para- | tolualdehyde | FL/FR |
sulfurous |
S- | ethyl thioacetate | FL |
sweet |
| acesulfame potassium | FL |
| acetone alcohol | FL |
| advantame | FL |
| agave flavor | FL |
| alitame anhydrous | FL |
| aspartame | FL |
| aspartame-acesulfame salt | FL |
| caramel dione | FL |
| corn syrup high fructose | FL |
| corn syrups | FL |
| dextrose monohydrate | FL |
3',7- | dihydroxy-4'-methoxyflavan | FL |
| ethyl 3-(2-hydroxyphenyl) propionate | FL |
| glucosyl steviol glycosides | FL |
| glycyrrhizic acid | FL |
| honey enhancer | FL |
| levulose | FL |
| luo han fruit concentrate | FL |
| maltitol | FL |
| maltose | FL |
| molasses | FL |
| molasses concentrate | FL |
| molasses distillates | FL |
| molasses flavor | FL |
laevo- | ornithine hydrochloride | FL |
| rebaudioside C | FL |
| rebaudioside C 30% | FL |
glucosylated | rubus suavissimus extract, 60% glucosylated rubusoside glycosides | FL |
| sodium 2-(4-methoxyphenoxy) propionate | FL |
dextro- | sorbitol | FL |
| stevia rebaudiana extract, rebaudioside A 22% | FL |
| stevia rebaudiana extract, rebaudioside A 60% | FL |
| stevia rebaudiana extract, rebaudioside A 80% | FL |
| steviol | FL |
| steviol glycoside extract, rebaudioside C 22% | FL |
enzyme modified | steviol glycosides | FL |
| stevioside | FL |
| sucralose | FL |
maple | sugar | FL |
| sugar | FL |
| sugar cane distillate | FL |
| sugar extenders | FL |
brown | sugar flavor | FL |
| sugar flavor | FL |
burnt | sugar flavor | FL |
| sugar replacers | FL |
| sweet & sour candy flavor | FL |
| sweet flavor | FL |
| thaumatin b-recombinant | FL |
| vanilla bean absolute (vanilla spp.) | FL/FR |
| vanilla concentrate | FL |
| vanilla oleoresin bali | FL/FR |
| vanilla resinoid | FL/FR |
| vanilla tahitensis fruit extract | FL/FR |
dextro,laevo- | xylose | FL |
tropical |
| propyl propionate | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| ethyl vanillin propylene glycol acetal | FL/FR |
| propenyl guaethol | FL/FR |
| vanilla aromatica fruit extract | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanilla oleoresin bourbon | FL/FR |
| vanillin | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
| vanillyl acetate | FL/FR |
| vanillyl isobutyrate | FL/FR |
vegetable |
| tyramine | FL |
waxy |
| ethyl decanoate | FL/FR |
| ethyl myristate | FL/FR |
| ethyl octanoate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hydroxycitronellal | FL/FR |
| nonanol | FL/FR |
| octyl butyrate | FL/FR |
4- | phenyl-3-buten-2-ol | FL/FR |
| propyl heptanoate | FL/FR |
| rhodinyl phenyl acetate | FL/FR |
woody |
4- | ethyl guaiacol | FL/FR |
alpha- | ionol | FL/FR |
alpha- | terpinyl methyl ether | FL/FR |
|
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
6-O-alpha-D- | glucopyranosyl-D-fructose | 6-O-alpha-dextro- | glucopyranosyl-dextro-fructose | | palatinose | (3S,4R,5R)-1,3,4,5- | tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one |
Articles:
PubMed: | Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice. |
PubMed: | The effect of using isomaltulose (Palatinose™) to modulate the glycaemic properties of breakfast on the cognitive performance of children. |
PubMed: | Synthesis and characterization of isomaltulose-derived oligosaccharides produced by transglucosylation reaction of Leuconostoc mesenteroides dextransucrase. |
PubMed: | Development of synbiotics with inulin, palatinose, alpha-cyclodextrin and probiotic bacteria. |
PubMed: | Comparison of the effects of slowly and rapidly absorbed carbohydrates on postprandial glucose metabolism in type 2 diabetes mellitus patients: a randomized trial. |
PubMed: | Transglycosylations employing recombinant α- and β-galactosidases and novel donor substrates. |
PubMed: | Current studies on sucrose isomerase and biological isomaltulose production using sucrose isomerase. |
PubMed: | Crystallization and preliminary X-ray crystallographic analysis of α-glucosidase HaG from Halomonas sp. strain H11. |
PubMed: | Functional characterization of the sucrose isomerase responsible for trehalulose production in plant-associated Pectobacterium species. |
PubMed: | The structural basis of Erwinia rhapontici isomaltulose synthase. |
PubMed: | The effect of lactose-isomaltulose-containing growing-up milks on cognitive performance of Indonesian children: a cross-over study. |
PubMed: | Is there a specific role for sucrose in sports and exercise performance? |
PubMed: | Simple, fast, and efficient process for producing and purifying trehalulose. |
PubMed: | Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity. |
PubMed: | Potential applications of carbohydrases immobilization in the food industry. |
PubMed: | Enhancing isomaltulose production by recombinant Escherichia coli producing sucrose isomerase: culture medium optimization containing agricultural wastes and cell immobilization. |
PubMed: | Mature-stem expression of a silencing-resistant sucrose isomerase gene drives isomaltulose accumulation to high levels in sugarcane. |
PubMed: | Influence of processing on the volatile profile of strawberry spreads made with isomaltulose. |
PubMed: | The effect of selected synbiotics on microbial composition and short-chain fatty acid production in a model system of the human colon. |
PubMed: | Transcriptional analysis of prebiotic uptake and catabolism by Lactobacillus acidophilus NCFM. |
PubMed: | Combining protein and carbohydrate increases postprandial insulin levels but does not improve glucose response in patients with type 2 diabetes. |
PubMed: | Insight into the role of sugars in bud burst under light in the rose. |
PubMed: | Metabolic effects of replacing sucrose by isomaltulose in subjects with type 2 diabetes: a randomized double-blind trial. |
PubMed: | Immobilization of glucosyltransferase from Erwinia sp. using two different techniques. |
PubMed: | Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinose™) ingestion. |
PubMed: | Reduced glycaemic and insulinaemic responses following trehalose and isomaltulose ingestion: implications for postprandial substrate use in impaired glucose-tolerant subjects. |
PubMed: | Microbial sucrose isomerases: producing organisms, genes and enzymes. |
PubMed: | Mechanism-oriented redesign of an isomaltulose synthase to an isomelezitose synthase by site-directed mutagenesis. |
PubMed: | Exercise dose and insulin sensitivity: relevance for diabetes prevention. |
PubMed: | Isomaltulose improves glycemia and maintains run performance in type 1 diabetes. |
PubMed: | Isomaltulose is actively metabolized in plant cells. |
PubMed: | The effect of high lactose-isomaltulose on cognitive performance of young children. A double blind cross-over design study. |
PubMed: | Field performance of transgenic sugarcane expressing isomaltulose synthase. |
PubMed: | Isomaltulose production via yeast surface display of sucrose isomerase from Enterobacter sp. FMB-1 on Saccharomyces cerevisiae. |
PubMed: | Immobilization of Erwinia sp. D12 Cells in Alginate-Gelatin Matrix and Conversion of Sucrose into Isomaltulose Using Response Surface Methodology. |
PubMed: | Sucrose isomerase and its mutants from Erwinia rhapontici can synthesise α-arbutin. |
PubMed: | GLP-1 secretion in response to oral and luminal palatinose (isomaltulose) in rats. |
PubMed: | A new immune-modulating diet enriched with whey-hydrolyzed peptide, fermented milk, and isomaltulose attenuates gut ischemia-reperfusion injury in mice. |
PubMed: | A combined insulin reduction and carbohydrate feeding strategy 30 min before running best preserves blood glucose concentration after exercise through improved fuel oxidation in type 1 diabetes mellitus. |
PubMed: | Studies on absorption and metabolism of palatinose (isomaltulose) in rats. |
PubMed: | Microbial production of palatinose through extracellular expression of a sucrose isomerase from Enterobacter sp. FMB-1 in Lactococcus lactis MG1363. |
PubMed: | Cloning and characterization of a sucrose isomerase from Erwinia rhapontici NX-5 for isomaltulose hyperproduction. |
PubMed: | Isomaltulose Improves Postexercise Glycemia by Reducing CHO Oxidation in T1DM. |
PubMed: | Transgenic expression of trehalulose synthase results in high concentrations of the sucrose isomer trehalulose in mature stems of field-grown sugarcane. |
PubMed: | Palatinose-blended sugar compared with sucrose: different effects on insulin sensitivity after 12 weeks supplementation in sedentary adults. |
PubMed: | Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose). |
PubMed: | Manipulation of glycemic response with isomaltulose in a milk-based drink does not affect cognitive performance in healthy adults. |
PubMed: | Effect of concentration and substrate flow rate on isomaltulose production from sucrose by Erwinia sp. cells immobilized in calcium-alginate using packed bed reactor. |
PubMed: | Sucrose: A prospering and sustainable organic raw material. |
PubMed: | Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45. |
PubMed: | Safer glycemic control using isomaltulose-based enteral formula: a pilot randomized crossover trial. |
PubMed: | Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use. |
PubMed: | Glucosylation of raffinose via alternansucrase acceptor reactions. |
PubMed: | Molecular cloning and functional characterization of a sucrose isomerase (isomaltulose synthase) gene from Enterobacter sp. FMB-1. |
PubMed: | Slowly digestible carbohydrate sources can be used to attenuate the postprandial glycemic response to the ingestion of diabetes-specific enteral formulas. |
PubMed: | Structural determinants of product specificity of sucrose isomerases. |
PubMed: | Isomaltulose production from sucrose by Protaminobacter rubrum immobilized in calcium alginate. |
PubMed: | Beneficial effects on glucose metabolism of chronic feeding of isomaltulose versus sucrose in rats. |
PubMed: | Isomalt production by cloning, purifying and expressing of the MDH gene from Pseudomonas fluorescens DSM 50106 in different strains of E. coli. |
PubMed: | [Physiological and biochemical properties of the bacterium Erwinia rhapontici, a producer of isomaltulose synthase]. |
PubMed: | Palatinose and oleic acid act together to prevent pancreatic islet disruption in nondiabetic obese Zucker rats. |
PubMed: | Food labeling: health claims; dietary noncariogenic carbohydrate sweeteners and dental caries. Final rule. |
PubMed: | Inhibitory action of palatinose and its hydrogenated derivatives on the hydrolysis of alpha-glucosylsaccharides in the small intestine. |
PubMed: | Isomaltose production by modification of the fructose-binding site on the basis of the predicted structure of sucrose isomerase from "Protaminobacter rubrum". |
PubMed: | Recent progress in the synthesis of carbohydrate-based amphiphilic materials: the examples of sucrose and isomaltulose. |
PubMed: | Molecular and physiological role of the trehalose-hydrolyzing alpha-glucosidase from Thermus thermophilus HB27. |
PubMed: | Role of periplasmic trehalase in uptake of trehalose by the thermophilic bacterium Rhodothermus marinus. |
PubMed: | [Production of fructooligosaccharide syrup from sucrose in combination with palatinose and trehalose]. |
PubMed: | Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats. |
PubMed: | Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. |
PubMed: | A palatinose-based balanced formula improves glucose tolerance, serum free fatty acid levels and body fat composition. |
PubMed: | Inhibitory effect of palatinose on glucose absorption in everted rat gut. |
PubMed: | Exogenous oxidation of isomaltulose is lower than that of sucrose during exercise in men. |
PubMed: | A new colorimetric method for determining the isomerization activity of sucrose isomerase. |
PubMed: | Effects of a novel palatinose based enteral formula (MHN-01) carbohydrate-adjusted fluid diet in improving the metabolism of carbohydrates and lipids in patients with esophageal cancer complicated by diabetes mellitus. |
PubMed: | Doubled sugar content in sugarcane plants modified to produce a sucrose isomer. |
PubMed: | Isomaltulose production using free cells: optimisation of a culture medium containing agricultural wastes and conversion in repeated-batch processes. |
PubMed: | Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men. |
PubMed: | Conversion of sucrose into isomaltulose by Enterobacter sp. FMB1, an isomaltulose-producing microorganism isolated from traditional Korean food. |
PubMed: | Application of response surface methodology to cell immobilization for the production of palatinose. |
PubMed: | Sucrose substitutes and their role in caries prevention. |
PubMed: | Molecular characterization of the alpha-glucosidase activity in Enterobacter sakazakii reveals the presence of a putative gene cluster for palatinose metabolism. |
PubMed: | Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA. |
PubMed: | Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45. |
PubMed: | Characterization of the highly efficient sucrose isomerase from Pantoea dispersa UQ68J and cloning of the sucrose isomerase gene. |
PubMed: | The high-affinity maltose/trehalose ABC transporter in the extremely thermophilic bacterium Thermus thermophilus HB27 also recognizes sucrose and palatinose. |
PubMed: | Klebsiella singaporensis sp. nov., a novel isomaltulose-producing bacterium. |
PubMed: | Comparative effect of repeated ingestion of difructose anhydride III and palatinose on the induction of gastrointestinal symptoms in humans. |
PubMed: | Effect of a novel palatinose-based liquid balanced formula (MHN-01) on glucose and lipid metabolism in male Sprague-Dawley rats after short- and long-term ingestion. |
PubMed: | Characterization of Pantoea dispersa UQ68J: producer of a highly efficient sucrose isomerase for isomaltulose biosynthesis. |
PubMed: | Fermentation of five sucrose isomers by human dental plaque bacteria. |
PubMed: | Enhanced conversion of sucrose to isomaltulose by a mutant of Erwinia rhapontici. |
PubMed: | Production of palatinose using Serratia plymuthica cells immobilized in chitosan. |
PubMed: | The effect of palatinose on mental concentration in humans. |
PubMed: | Straightforward route for anchoring a glucosyl moiety onto nucleophilic species: reaction of amines and alcohols with carboxymethyl 3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 2-O-lactone. |
PubMed: | Substrate induction of isomaltulose synthase in a newly isolated Klebsiella sp. LX3. |
PubMed: | Isomaltulose synthase (PalI) of Klebsiella sp. LX3. Crystal structure and implication of mechanism. |
PubMed: | Distinct sucrose isomerases catalyze trehalulose synthesis in whiteflies, Bemisia argentifolii, and Erwinia rhapontici. |
PubMed: | Structural and functional analysis of a putative gene cluster for palatinose transport on the linear chromosome of Agrobacterium tumefaciens MAFF301001. |
PubMed: | Sugar-regulated expression of a putative hexose transport gene in grape. |
PubMed: | A motif rich in charged residues determines product specificity in isomaltulose synthase. |
PubMed: | Decreased sucrose content triggers starch breakdown and respiration in stored potato tubers (Solanum tuberosum). |
PubMed: | Expression, crystallization and preliminary X-ray analysis of isomaltulose synthase (PalI) from Klebsiella sp. LX3. |
PubMed: | Glycosidation of fructose-containing disaccharides using MCM-41 material as the catalyst. |
PubMed: | 13-Week oral toxicity study with isomaltulose (Palatinose) in rats. |
PubMed: | Isomaltulose (Palatinose): a review of biological and toxicological studies. |
PubMed: | Potato tubers as bioreactors for palatinose production. |
PubMed: | Isomaltulose synthase from Klebsiella sp. strain LX3: gene cloning and characterization and engineering of thermostability. |
PubMed: | Metabolizable and non-metabolizable sugars activate different signal transduction pathways in tomato. |
PubMed: | High-level production of the non-cariogenic sucrose isomer palatinose in transgenic tobacco plants strongly impairs development. |
PubMed: | Phosphorylation and metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae. |
PubMed: | The sucrose analog palatinose leads to a stimulation of sucrose degradation and starch synthesis when supplied to discs of growing potato tubers. |
PubMed: | Responses of the ant Lasius niger to various compounds perceived as sweet in humans: a structure-activity relationship study. |
PubMed: | Cloning and characterization of the gene cluster for palatinose metabolism from the phytopathogenic bacterium Erwinia rhapontici. |
PubMed: | Assessment of acid production by various human oral micro-organisms when palatinose or leucrose is utilized. |
PubMed: | Di- and oligosaccharide substrate specificities and subsite binding energies of pig intestinal glucoamylase-maltase. |
PubMed: | Effects of frequent mouthrinses with palatinose and xylitol on dental plaque. |
PubMed: | Bacillus thermoamyloliquefaciens KP1071 alpha-glucosidase II is a thermostable M(r) 540,000 homohexameric alpha-glucosidase with both exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. |
PubMed: | Embryotoxicity/teratogenicity study with isomaltulose (Palatinose) in rats. |
PubMed: | The effects of isomaltulose, isomalt, and isomaltulose-based oligomers on mineral absorption and retention. |
PubMed: | Urinary excretion by dogs of intravenously administered simple sugars. |
PubMed: | The effects of isomaltulose-based oligomers feeding and calcium deficiency on mineral retention in rats. |
PubMed: | Industrial application of immobilized biocatalysts in Japan. |
PubMed: | Transglucosylation with 6'-chloro-6'-deoxysucrose and immobilized isomaltulose-producing microorganisms using 2,2-dimethyl-1,3-dioxolane-4-methanol and its related compounds as acceptors. Steric and chemical requirement of the glucosyl acceptor. |
PubMed: | Characterization of alpha-glucosyltransferase from Pseudomonas mesoacidophila MX-45. |
PubMed: | Downstream processing of sucrose 6-glucosylmutase and production of isomaltulose, a non-cariogenic, low-caloric sweetener. |
PubMed: | Synthesis of dispirodioxanyl pseudo-oligosaccharides by selective protonic activation of isomeric glycosylfructoses in anhydrous hydrogen fluoride. |
PubMed: | Investigation of sucrose synthase from rice for the synthesis of various nucleotide sugars and saccharides. |
PubMed: | Selective protonic activation of isomeric glycosylfructoses with pyridinium poly(hydrogen fluoride) and synthesis of spirodioxanyl oligosaccharides. |
PubMed: | Trehalulose does not induce dental caries in rats infected with mutans streptococci. |
PubMed: | First purification and characterization of a sucrase-isomaltase from goose kidney microvillous membrane. |
PubMed: | Plaque formation of dietary isomaltulose in humans. |
PubMed: | Evaluation of a model for short-term clinical testing of cariogenicity. |
PubMed: | Usefulness of palatinose as a caloric sweetener for diabetic patients. |
PubMed: | Isomaltulose "palatinose". An anticariogenic substitute for glucose. |
PubMed: | Hydrolysis of alpha-D-glucopyranosyl-1,6-sorbitol and alpha-D-glucopyranosyl-1,6-mannitol by rat intestinal disaccharidases. |
PubMed: | [Sugar substitutes--new substances]. |
PubMed: | New experiments on Palatinose (Isomaltulose) as a sugar substitute. |
PubMed: | [Effect of candy containing palatinose on human dental plaque formation]. |
PubMed: | [A stepwise method of evaluating sugar substitutes--a preliminary study using enzymes. 2. Beta-fructosidase from yeast]. |
PubMed: | Effects of parenteral palatinose on glucose metabolism in normal and streptozotocin diabetic rats. |
PubMed: | Palatinose as a potential parenteral nutrient: its metabolic effects and fate after oral and intravenous administration to dogs. |
PubMed: | Changes in blood glucose and insulin after an oral palatinose administration in normal subjects. |
PubMed: | [New sucrose substitutes]. |
PubMed: | Isomaltulose production using immobilized cells. |
PubMed: | Microbiological aspects of some caloric sugar substitutes. |
PubMed: | New trends on sweeteners in Japan. |
PubMed: | [Non-cariogenicity of palatinose]. |
PubMed: | [Caries-inducing activity of Palatinose syrup]. |
PubMed: | Cariogenicity of isomaltulose (palatinose), sucrose and mixture of these sugars in rats infected with Streptococcus mutans E-49. |
PubMed: | Palatinose--a sucrose substitute. Pilot studies. |
PubMed: | The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici. |
PubMed: | [Effect of sugar substitutes on the growth and acid production of 2 types of acidogenic bacteria of the oral cavity]. |
PubMed: | Virulence factors of Streptococcus mutans and dental caries prevention. |
PubMed: | Effect of frequent rinses with isomaltulose (Palatinose) solution on acid production in human dental plaque. |
PubMed: | [Oligosaccharides produced by Streptococcus mutans glucosyltransferase from sucrose with isomaltulose]. |
PubMed: | Cariostatic effect of palatinose on experimental dental caries in rats. |
PubMed: | [Dental caries and palatinose, a structural isomer of sucrose]. |
PubMed: | Effect of isomaltulose on acid production and insoluble glucan synthesis by Streptococcus mutans. |
PubMed: | Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats. |
PubMed: | Acid production from isomaltulose, sucrose, sorbitol, and xylitol in suspensions of human dental plaque. |
PubMed: | Carbohydrate transformations by immobilized cells. |
PubMed: | [Inhibitory mechanism of isomaltulose for insoluble glucan synthesis by Streptococcus mutans (author's transl)]. |
PubMed: | [Analytical characterization of palatinit (author's transl)]. |
PubMed: | [Formation of acids by cariogenically important streptococci from sugars and sugar alcohols with special reference to isomaltitol and isomaltulose]. |
PubMed: | Human intestinal disaccharidases and hereditary disaccharide intolerance. The hydrolysis of sucrose, isomaltose, palatinose (isomaltulose), and a 1,6-alpha-oligosaccharide (isomalto-oligosaccharide) preparation. |
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