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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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| Odor Type: spicy |
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| Odor Strength: | medium |
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| | spicy clove calamus |
Odor Description:
at 100.00 %. | spicy clove |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-guinea pig LD50 297 mg/kg
BEHAVIORAL: TETANY
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Antibiotics and Chemotherapy Vol. 7, Pg. 378, 1957.
intraperitoneal-mouse LD50 177 mg/kg
Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 163, 1959.
intravenous-mouse LD50 1138 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Dissertationes Pharmaceuticae. Vol. 16, Pg. 447, 1964.
intraperitoneal-rat LD50 221 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.
oral-rat LD50 777 mg/kg
BEHAVIORAL: TREMOR
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
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| Dermal Toxicity: |
skin-guinea pig LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | fragrance agents |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| IFRA fragrance material specification: | | | cis- and trans-Asarone as such should not be used as fragrance ingredients; essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in consumer products. |
| contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only) |
| methyl eugenol | Max. Found: <0.90 % and Reason: Potential carcinogenic activity in animals |
| Recommendation for calamus leaf oil usage levels up to: | | | 3.0000 % in the fragrance concentrate.
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| Recommendation for calamus leaf oil flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| Chemical Carcinogenesis Research Information System: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 8015-79-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| | acorus calamus l. leaf oil |
| Chemidplus: | 0008015790 |
References:
Other Information:
Potential Blenders and core components notePotential Uses:
Occurrence (nature, food, other): noteSynonyms:
| | acorus americanus leaf oil | | | acorus angustatus leaf oil | | | acorus angustifolius leaf oil | | | acorus asiaticus leaf oil | | | acorus calamus leaf oil | | | acorus calamus var. americanus leaf oil | | | acorus calamus var. angustatus leaf oil | | | acorus calamus var. angustifolius leaf oil | | | acorus calamus var. spurius leaf oil | | | acorus calamus var. verus leaf oil | | | acorus calamus var. vulgaris leaf oil | | | acorus cochinchinensis leaf oil | | | acorus griffithii leaf oil | | | acorus spurius leaf oil | | | acorus triqueter leaf oil | | | acorus verus leaf oil | | | orontium cochinchinense leaf oil |
Articles:
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