PubMed: | Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of Mitogen-Ac |
PubMed: | Ferruginol exhibits anticancer effects in OVCAR?3 human ovary cancer cells by inducing apoptosis, inhibition of cancer cell migration and G2/M phase cell cycle arrest |
PubMed: | Ferruginol inhibits non-small cell lung cancer growth by inducing caspase-associated apoptosis |
PubMed: | Ferruginol induced apoptosis on SK-Mel-28 human malignant melanoma cells mediated through P-p38 and NF-?B |
PubMed: | Ameliorative effect of ferruginol on isoprenaline hydrochloride-induced myocardial infarction in rats |
PubMed: | Antioxidant activity and mechanism of the abietane-type diterpene ferruginol |
PubMed: | Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells |
PubMed: | Anti-Zika virus activity of several abietane-type ferruginol analogues |
PubMed: | Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-? Injury in Hippocampal Neurons |
PubMed: | The accumulation pattern of ferruginol in the heartwood-forming Cryptomeria japonica xylem as determined by time-of-flight secondary ion mass spectrometry and quantity analysis |
PubMed: | Gastroprotective activity of ferruginol in mice and rats: effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls |
PubMed: | A GC-MS method validation for quantitative investigation of some chemical markers in Salvia hypargeia Fisch. & C.A. Mey. of Turkey: Enzyme inhibitory potential of ferruginol |
PubMed: | Epicubenol and Ferruginol induce DC from human monocytes and differentiate IL-10-producing regulatory T cells in vitro |
PubMed: | Determination of ferruginol in rat plasma via high-performance liquid chromatography and its application in pharmacokinetics study |
PubMed: | Anti-herpetic and anti-dengue activity of abietane ferruginol analogues synthesized from (+)-dehydroabietylamine |
PubMed: | Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models |
PubMed: | Gastroprotective and cytotoxic effect of semisynthetic ferruginol derivatives |
PubMed: | Proteomics investigation reveals cell death-associated proteins of basidiomycete fungus Trametes versicolor treated with Ferruginol |
PubMed: | Antimalarial activity of abietane ferruginol analogues possessing a phthalimide group |
PubMed: | Totarol, totaradiol and ferruginol: three diterpenes from Thuja plicata (Cupressaceae) |
PubMed: | Localization of ferruginol, a diterpene phenol, in Cryptomeria japonica heartwood by time-of-flight secondary ion mass spectrometry |
PubMed: | New gastroprotective ferruginol derivatives with selective cytotoxicity against gastric cancer cells |
PubMed: | CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts |
PubMed: | [Discussion on research idea of quality marker of Salvia miltiorrhiza based on biosynthetic pathway of tanshinone compounds] |
PubMed: | [Retracted] Ferruginol exhibits anticancer effects in OVCAR?3 human ovary cancer cells by inducing apoptosis, inhibition of cancer cell migration and G2/M phase cell cycle arrest |
PubMed: | Enantioselective, Lewis Base-Catalyzed Sulfenocyclization of Polyenes |
PubMed: | Retracted: Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of |
PubMed: | Aromatic abietane diterpenoids: their biological activity and synthesis |
PubMed: | Antiprotozoal Diterpenes from Perovskia abrotanoides |
PubMed: | Synthesis of (-)-Chamobtusin A from (+)-Dehydroabietylamine |
PubMed: | CYP76 Oxidation Network of Abietane Diterpenes in Lamiaceae Reconstituted in Yeast |
PubMed: | Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues |
PubMed: | Terpenoids of the Swamp Cypress Subfamily (Taxodioideae), Cupressaceae, an Overview by GC-MS |
PubMed: | Synthesis, Antiviral and Cytotoxic Activity of Novel Terpenyl Hybrid Molecules Prepared by Click Chemistry |
PubMed: | Terpenoid Compositions of Resins from Callitris Species (Cupressaceae) |
PubMed: | Enantioselective Polyene Cyclization Catalyzed by a Chiral Br?nsted Acid |
PubMed: | Synthetic derivatives of aromatic abietane diterpenoids and their biological activities |
PubMed: | Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies |
PubMed: | Antibiotic potentiation of natural products: A promising target to fight pathogenic bacteria |
PubMed: | Cytotoxic and apoptogenic properties of three isolated diterpenoids from Salvia chorassanica through bioassay-guided fractionation |
PubMed: | Biochemical characterization of diterpene synthases of Taiwania cryptomerioides expands the known functional space of specialized diterpene metabolism in gymnosperms |
PubMed: | Functional Integration of Two CYP450 Genes Involved in Biosynthesis of Tanshinones for Improved Diterpenoid Production by Synthetic Biology |
PubMed: | High Yield of Bioactive Abietane Diterpenes in Salvia sclarea Hairy Roots by Overexpressing Cyanobacterial DXS or DXR Genes |
PubMed: | Boosting the Synthesis of Pharmaceutically Active Abietane Diterpenes in S. sclarea Hairy Roots by Engineering the GGPPS and CPPS Genes |
PubMed: | A functional genomics approach to tanshinone biosynthesis provides stereochemical insights |
PubMed: | Functional expression of two NADPH-cytochrome P450 reductases from Siraitia grosvenorii |
PubMed: | [Construction of Saccharomyces cerevisiae whole-cell biocatalyst system for conversion miltiradiene] |
PubMed: | Tandem single-step construction of chiral hexahydrophenanthrenes: a concise route to (+)-ferruginol |
PubMed: | Functional Diversification of Kaurene Synthase-Like Genes in Isodon rubescens |
PubMed: | ACAT inhibitory activity of exudates from Calocedrus macrolepis var. formosana |
PubMed: | Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast |
PubMed: | Diterpenoids from Salvia prionitis |
PubMed: | Salvisertin A, a New Hexacyclic Triterpenoid, and Other Bioactive Terpenes from Salvia deserta Root |
PubMed: | Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana |
PubMed: | Engineering of CYP76AH15 can improve activity and specificity towards forskolin biosynthesis in yeast |
PubMed: | Terpenoids from Salvia sclarea |
PubMed: | Constituents from fruits of Cupressus sempervirens |
PubMed: | Novel domino reactions for diterpene synthesis |
PubMed: | Efficient Separation of Four Antibacterial Diterpenes from the Roots of Salvia Prattii Using Non-Aqueous Hydrophilic Solid-Phase Extraction Followed by Preparative High-Performance Liquid Chromatography |
PubMed: | Bioinspired Synthesis of Pygmaeocins and Related Rearranged Abietane Diterpenes: Synthesis of Viridoquinone |
PubMed: | Coactivation of MEP-biosynthetic genes and accumulation of abietane diterpenes in Salvia sclarea by heterologous expression of WRKY and MYC2 transcription factors |
PubMed: | Gastroprotective effect and cytotoxicity of carnosic acid derivatives |
PubMed: | Composition, antioxidant, antimicrobial and anti-wood-decay fungal activities of the twig essential oil of Taiwania cryptomerioides from Taiwan |
PubMed: | Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae |
PubMed: | Antimicrobial and Antileishmanial Activities of Diterpenoids Isolated from the Roots of Salvia deserta |
PubMed: | Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells |
PubMed: | Bioactive compounds from Taiwania cryptomerioides |
PubMed: | Isolation of antibacterial diterpenoids from Cryptomeria japonica bark |
PubMed: | Molecular cloning and functional characterization of multiple NADPH-cytochrome P450 reductases from Andrographis paniculata |
PubMed: | Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones |
PubMed: | Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B |
PubMed: | Abietane diterpenoids from Salvia sclarea transformed roots as growth inhibitors of pathogenic Acanthamoeba spp |
PubMed: | Antiparasitic, nematicidal and antifouling constituents from Juniperus berries |
PubMed: | Topical Anti-inflammatory Activity of New Hybrid Molecules of Terpenes and Synthetic Drugs |
PubMed: | In vitro and in vivo antitumor effects of the diterpene-enriched extract from Taxodium ascendens through the mitochondrial-dependent apoptosis pathway |
PubMed: | Comparative evaluation of cytotoxic, antimicrobial and antioxidant activities of the crude extracts of three Plectranthus species grown in Saudi Arabia |
PubMed: | Cardioactive diterpenes from the roots of Salvia eriophora |
PubMed: | Discovery and characterization of diterpene synthases in Chamaecyparis formosensis Matsum. which participated in an unprecedented diterpenoid biosynthesis route in conifer |
PubMed: | Antifungal abietane-type diterpenes from the cones of Taxodium distichum Rich |
PubMed: | Seasonal variation and resin composition in the Andean tree Austrocedrus chilensis |
PubMed: | Terpenoids, flavonoids and caffeic acid derivatives from Salvia viridis L. cvar. Blue Jeans |
PubMed: | Homology modeling, molecular dynamics, and virtual screening of NorA efflux pump inhibitors of Staphylococcus aureus |
PubMed: | Terpenoids Preserved in Fossils from Miocene-aged Japanese Conifer Wood |
PubMed: | Mosquito larvicidal activities of extractives from black heartwood-type Cryptomeria japonica |
PubMed: | Anti-tumor abietane diterpenes from the cones of Sequoia sempervirens |
PubMed: | Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: cytological studies and chemical investigations |
PubMed: | Components and antibacterial activity of the roots of Salvia jaminiana |
PubMed: | RNA interference targeting CYP76AH1 in hairy roots of Salvia miltiorrhiza reveals its key role in the biosynthetic pathway of tanshinones |
PubMed: | Diterpenes from the fruits of Vitex rotundifolia |
PubMed: | Combined metabolome and transcriptome profiling provides new insights into diterpene biosynthesis in S. pomifera glandular trichomes |
PubMed: | Antifeedants against Locusta migratoria from the Japanese Cedar, Cryptomeria japonica II |
PubMed: | New Diterpenoids from the Roots of Salvia triloba |
PubMed: | Diterpenoid production in hairy root culture of Salvia sclarea L |
PubMed: | In vitro and in vivo antiplasmodial activity of three Rwandan medicinal plants and identification of their active compounds |
PubMed: | Antimicrobial diterpenes from the seeds of Cephalotaxus harringtonia var. drupacea |
PubMed: | Antibacterial diterpenes from the roots of Salvia viridis |
PubMed: | Diterpenes from Cryptomeria japonica inhibit androgen receptor transcriptional activity in prostate cancer cells |
PubMed: | Diterpenes from Salvia broussonetii transformed roots and their insecticidal activity |
PubMed: | Inhibition of osteoclast differentiation by tanshinones from the root of Salvia miltiorrhiza bunge |
PubMed: | [Study on chemical constituents from rhizome of Rabdosia flavida] |
PubMed: | New abietane norditerpenoid from Salvia miltiorrhiza with cytotoxic activities |
PubMed: | Abietane diterpenoids from suspension cultured cells of Torreya nucifera var. radicans |
PubMed: | Potential antitumor promoting diterpenoids from the stem bark of Thuja standishii |
PubMed: | A new abietane and two dimeric abietane diterpenes from the black heartwood of Cryptomeria japonica |
PubMed: | Synthesis of variously oxidized abietane diterpenes and their antibacterial activities against MRSA and VRE |
PubMed: | Preparative mass-spectrometry profiling of bioactive metabolites in Saudi-Arabian propolis fractionated by high-speed countercurrent chromatography and off-line atmospheric pressure chemical ionization mass-spectrometry injection |
PubMed: | Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis |
PubMed: | Efficient ortho-oxidation of phenol and synthesis of anti-MRSA and anti-VRE compound abietaquinone methide from dehydroabietic acid |
PubMed: | Medicinal compounds, chemically and biologically characterised from extracts of Australian Callitris endlicheri and C.glaucophylla (Cupressaceae): used traditionally in Aboriginal and colonial pharmacopoeia |
PubMed: | Xanthine oxidase inhibitory terpenoids of Amentotaxus formosana protect cisplatin-induced cell death by reducing reactive oxygen species (ROS) in normal human urothelial and bladder cancer cells |
PubMed: | Abietane diterpenoids and triterpenoic acids from Salvia cilicica and their antileishmanial activities |
PubMed: | Three abietane diterpenes and two diterpenes incorporated sesquiterpenes from the bark of Cryptomeria japonica |
PubMed: | Cytotoxic and proapoptotic activity of diterpenoids from in vitro cultivated Salvia sclarea roots. Studies on the leukemia cell lines |
PubMed: | Terpenoids from Juniperus procera with hepatoprotective activity |
PubMed: | Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations |
PubMed: | Antimite activity of essential oils and their constituents from Taiwania cryptomerioides |
PubMed: | New diterpenoids and cytotoxic and anti-inflammatory diterpenoids from Amentotaxus formosana |
PubMed: | Biota: sediment partitioning of aluminium smelter related PAHs and pulp mill related diterpenes by intertidal clams at Kitimat, British Columbia |
PubMed: | Antimicrobial activity of diterpenoids from hairy roots of Salvia sclarea L.: salvipisone as a potential anti-biofilm agent active against antibiotic resistant Staphylococci |
PubMed: | Chemical composition and termiticidal activity of essential oils from different tissues of Chinese cedar (cryptomeria fortunei) |
PubMed: | Composition, antioxidant and antimicrobial activities of the seed essential oil of Calocedrus formosana from Taiwan |
PubMed: | Trypanocidal activity of abietane diterpenoids from the roots of Craniolaria annua |
PubMed: | Bioactivity assay of extracts from Calocedrus macrolepis var. formosana bark |
PubMed: | Antitermitic activities of abietane-type diterpenes from Taxodium distichum cones |
PubMed: | An interpopulation study of the essential oils of Cistus parviflorus L. growing in Crete (Greece) |
PubMed: | Cardioactive diterpenoids from the roots of Salvia amplexicaulis |
PubMed: | [The structure of trijuganone C from Salvia trijuga] |
PubMed: | Biomolecules preserved in ca. 168 million year old fossil conifer wood |
PubMed: | New sesquiterpene and triterpene from the fruits of Cryptomeria fortunei |
PubMed: | Antitermitic activity of essential oils and components from Taiwania (Taiwania cryptomerioides) |
PubMed: | Cardioactive terpenoids and a new rearranged diterpene from Salvia syriaca |
PubMed: | Diterpenes and norditerpenes from the roots of Dorystoechas hastata |
PubMed: | Allelochemical resistance of bald cypress,Taxodium distichum, heartwood to the subterranean termite,Coptotermes formosanus |