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O-ethyl S-(2-furylmethyl)thiocarbonate
Notes:
Used as a food additive [EAFUS]
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Chemical sources Association Inc Exchange of knowledge Need This Item for Flavor? You can contact the Chemical Sources Association. Events Links Product(s):
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| CAS Number: | 376595-42-5 |  3D/inchi
|
| FDA UNII: | 1AZ807769B | |
| XlogP3-AA: | 2.00 (est) | |
| Molecular Weight: | 186.23030000 | |
| Formula: | C8 H10 O3 S | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | No longer supported by industry. | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1526 O-ethyl S-(2-furylmethyl)thiocarbonate |
| FEMA Number: | 4043 O-ethyl S-(2-furylmethyl)thiocarbonate |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 376595-42-5 ; O-ETHYL S-(2-FURYLMETHYL)THIOCARBONATE |
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.16700 to 1.17300 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 9.711 to 9.761 |
| Refractive Index: | 1.50400 to 1.51000 @ 20.00 °C. |
| Boiling Point: | 130.00 to 135.00 °C. @ 760.00 mm Hg |
| Acid Value: | 5.00 max. KOH/g |
| Soluble in: | |
| alcohol | |
| water, very slightly | |
| water, 565.9 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor Type: spicy | |
| spicy floral | |
| Odor Description: at 0.10 % in dipropylene glycol. | spicy floral |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Axsyn |
| For experimental / research use only. |
| Carbonothioic acid,O-ethyl S-(2-furanylmethyl) ester |
| Parchem |
| O-ethyl S-(2-furyl methyl) thiocarbonate |
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the CSA |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for O-ethyl S-(2-furyl methyl) thiocarbonate usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.61 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.90 (μg/capita/day) | ||
| Structure Class: | III | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 21 | |||
| Click here to view publication 21 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 0.03000 | 0.06000 | |
| beverages(nonalcoholic): | 0.03000 | 0.06000 | |
| beverages(alcoholic): | 0.03000 | 0.06000 | |
| breakfast cereal: | 0.03000 | 0.06000 | |
| cheese: | 0.03000 | 0.06000 | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | 0.03000 | 0.06000 | |
| fruit ices: | - | - | |
| gelatins / puddings: | 0.03000 | 0.06000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | 0.03000 | 0.06000 | |
| imitation dairy: | 0.03000 | 0.06000 | |
| instant coffee / tea: | 0.03000 | 0.06000 | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | 0.03000 | 0.06000 | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | 0.03000 | 0.06000 | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 67 Revision 2 (FGE.67Rev2): Consideration of 28 furan-substituted compounds evaluated by JECFA at the 55th, 65th and 69th meetings (JECFA, 2001, 2006a, 2009b) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 67, Revision 3 (FGE.67Rev3): consideration of 23 furan-substituted compounds evaluated by JECFA at the 55th, 65th, 69th and 86th meetings View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 15540144 |
| National Institute of Allergy and Infectious Diseases: | Data |
| O-ethyl S-(furan-2-ylmethyl) carbonothioate | |
| Chemidplus: | 0376595425 |
References:
| O-ethyl S-(furan-2-ylmethyl) carbonothioate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 15540144 |
| Pubchem (sid): | 163642298 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB009967 |
| ChemSpider: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
Potential Uses:
| floral | FR | |
| spice | FL |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| carbonothioic acid O-ethyl S-(2-furanyl methyl) ester | |
| carbonothioic acid O-ethyl S-(2-furanylmethyl) ester | |
| carbonothioic acid, O-ethyl S-(2-furanylmethyl) ester | |
| ethoxy carbonyl furfurylthiol | |
| ethoxycarbonyl furfuryl thiol | |
| ethoxycarbonylfurfurylthiol | |
| O- | ethyl S-(2-furanyl methyl) thiocarbonate |
| O- | ethyl S-(2-furanylmethyl)thiocarbonate |
| O- | ethyl S-(2-furylmethyl)thiocarbonate |
| O- | ethyl S-(furan-2-ylmethyl) carbonothioate |
| O- | ethyl S-(furan-2-ylmethyl) thiocarbonate |