Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Soluble in: |
| water, 16.36 mg/L @ 25 °C (est) |
Organoleptic Properties:
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for beta-agarofuran usage levels up to: | | not for fragrance use.
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Recommendation for beta-agarofuran flavor usage levels up to: |
| not for flavor use.
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Safety References:
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
Laboratory Chemical Safety Summary : | 6431303 |
| (1S,9R)-6,10,10-trimethyl-11-oxatricyclo[7.2.1.01,6]dodec-2-ene |
References:
| (1S,9R)-6,10,10-trimethyl-11-oxatricyclo[7.2.1.01,6]dodec-2-ene |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 6431303 |
Pubchem (cas): | NF0398 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
(1S,9R)-6,10,10- | trimethyl-11-oxatricyclo[7.2.1.01,6]dodec-2-ene |
Articles:
PubMed: | A dihydro-β-agarofuran sesquiterpene from Maytenus boaria. |
PubMed: | Celastrofurans A-G: Dihydro-β-agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells. |
PubMed: | Fungal Endophytes: an Alternative Source for Production of Volatile Compounds from Agarwood Oil of Aquilaria subintegra. |
PubMed: | Absolute Configuration of Dihydro-β-agarofuran Sesquiterpenes from Maytenus jelskii and Their Potential Antitumor-Promoting Effects. |
PubMed: | Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis. |
PubMed: | Dihydro-β-agarofuran sesquiterpene polyesters isolated from the stems of Tripterygium regelii. |
PubMed: | Dihydro-β-agarofuran sesquiterpenes from celastraceae species as anti-tumour-promoting agents: Structure-activity relationship. |
PubMed: | Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance. |
PubMed: | Chemical constituents of essential oils from the leaves, stems, roots and fruits of Alpinia polyantha. |
PubMed: | Further Study on Chemical Constituents of Parnassia wightiana Wall: Four New Dihydro-β-agarofuran Sesquiterpene Polyesters. |
PubMed: | Restoration of Chemosensitivity in P-Glycoprotein-Dependent Multidrug-Resistant Cells by Dihydro-β-agarofuran Sesquiterpenes from Celastrus vulcanicola. |
PubMed: | Nitrogen-containing dihydro-β-agarofuran derivatives from Tripterygium wilfordii. |
PubMed: | New dihydro-β-agarofuran sesquiterpenes from Parnassia wightiana wall: isolation, identification and cytotoxicity against cancer cells. |
PubMed: | Wightianines A-E, dihydro-β-agarofuran sesquiterpenes from Parnassia wightiana, and their antifungal and insecticidal activities. |
PubMed: | Activation and silencing of secondary metabolites in Streptomyces albus and Streptomyces lividans after transformation with cosmids containing the thienamycin gene cluster from Streptomyces cattleya. |
PubMed: | Semisynthesis and antifeedant activity of new derivatives of a dihydro-β-agarofuran from Parnassia wightiana. |
PubMed: | Antiplasmodial sesquiterpenes from the seeds of Salacia longipes var. camerunensis. |
PubMed: | Agarofuran sesquiterpenes from Schaefferia argentinensis. |
PubMed: | Overcoming human P-glycoprotein-dependent multidrug resistance with novel dihydro-β-agarofuran sesquiterpenes. |
PubMed: | Dihydro-β-agarofuran sesquiterpenoids from Plenckia integerrima. |
PubMed: | Dihydro-β-agarofuran sesquiterpenes isolated from Celastrus vulcanicola as potential anti-Mycobacterium tuberculosis multidrug-resistant agents. |
PubMed: | Chemical composition of volatile oils of Aquilaria malaccensis (Thymelaeaceae) from Malaysia. |
PubMed: | Dihydro-beta-agarofuran sesquiterpenes and pentacyclic triterpenoids from the root bark of Osyris lanceolata. |
PubMed: | Three new insecticidal sesquiterpene polyol esters from Celastrus angulatus. |
PubMed: | Facile synthesis of hydroxy wilfordic acid, a esterifying unit of anti-HIV sesquiterpene pyridine alkaloids. |
PubMed: | Sesquiterpenes from Maytenus jelskii as potential cancer chemopreventive agents. |
PubMed: | Novel dihydro-beta-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance. |
PubMed: | Inhibition of acetylcholinesterase activity by dihydro-beta-agarofuran sesquiterpenes isolated from Chilean Celastraceae. |
PubMed: | Inhibition of human cytomegalovirus IE gene expression by dihydro-beta-agarofuran sesquiterpenes isolated from Euonymus species. |
PubMed: | Sesquiterpenes from Celastrus vulcanicola as photosynthetic inhibitors. |
PubMed: | Cytotoxic dihydroagarofuranoid sesquiterpenes from the seeds of Celastrus orbiculatus. |
PubMed: | The dihydro-beta-agarofuran sesquiterpenoids. |
PubMed: | Biological evaluation, structure-activity relationships, and three-dimensional quantitative structure-activity relationship studies of dihydro-beta-agarofuran sesquiterpenes as modulators of P-glycoprotein-dependent multidrug resistance. |
PubMed: | Identification of a new sesquiterpene polyol ester from Celastrus paniculatus. |
PubMed: | Antitumor-promoting effects of new sesquiterpenes from Crossopetalum tonduzii. |
PubMed: | Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux. |
PubMed: | Insights into the molecular mechanism of action of Celastraceae sesquiterpenes as specific, non-transported inhibitors of human P-glycoprotein. |
PubMed: | Dihydro-beta-agarofuran sesquiterpenes: a new class of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in the protozoan parasite Leishmania. |
PubMed: | Reversion of human Pgp-dependent multidrug resistance by new sesquiterpenes from Zinowiewia costaricensis. |
PubMed: | Functional expression of a multidrug P-glycoprotein transporter of Leishmania. |
PubMed: | Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. |
PubMed: | New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus. |
PubMed: | Biotransformation of 3alpha,4alpha-dihydroxy-dihydro-beta-agarofuran by Rhizopus nigricans. |
PubMed: | Six new sesquiterpenes from Euonymus nanoides and their antitumor effects. |
PubMed: | SAR studies of dihydro-beta-agarofuran sesquiterpenes as inhibitors of the multidrug-resistance phenotype in a Leishmania tropica line overexpressing a P-glycoprotein-like transporter. |
PubMed: | Absolute configuration of sesquiterpenes from Crossopetalum tonduzii and their inhibitory effects on Epstein-Barr virus early antigen activation in Raji cells. |
PubMed: | A new sesquiterpene ester from the fruits of Celastrus orbiculatus. |
PubMed: | Absolute configuration and complete assignment of 13C NMR data for new sesquiterpenes from Maytenus chiapensis. |
PubMed: | New sesquiterpenes from Euonymus europaeus (Celastraceae). |
PubMed: | Antiinflammatory constituents of Celastrus orbiculatus inhibit the NF-kappaB activation and NO production. |
PubMed: | Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis. |
PubMed: | Insect growth regulator and insecticidal activity of beta-dihydroagarofurans from Maytenus spp. (Celastraceae). |
PubMed: | Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (Celastraceae). |
PubMed: | New terpenoids from Maytenus blepharodes. |
PubMed: | New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line. |
PubMed: | Sesquiterpene esters from Celastrus orbiculatus and their structure-activity relationship on the modulation of multidrug resistance. |
PubMed: | New sesquiterpenes from Crossopetalum tonduzii. |
PubMed: | A new sesquiterpene ester from Celastrus orbiculatus reversing multidrug resistance in cancer cells. |
PubMed: | Absolute configuration of beta-agarofuran nucleus of euojaponine C by CD exciton chirality method. |
PubMed: | New sesquiterpenes fromMaytenus species (Celastraceae). Taxonomic and chemotaxonomic considerations concerning chileanMaytenus. |
PubMed: | Minor sesquiterpenes from Maytenus chubutensis. |
PubMed: | [Studies on the chemical constituents of Aquilaria sinensis (Lour) Gilg. III. Elucidation of the structure of isobaimuxinol and isolation and identification of the constituents of lower boiling fraction of the volatile oil]. |
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