Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Boiling Point: | 269.00 to 270.00 °C. @ 760.00 mm Hg (est)
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Vapor Pressure: | 0.007000 mmHg @ 25.00 °C. (est) |
Flash Point: | 265.00 °F. TCC ( 129.20 °C. ) (est)
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logP (o/w): | -0.246 (est) |
Soluble in: |
| alcohol |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: caramellic |
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| caramellic |
Odor Description:
| caramellic |
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Flavor Type: creamy |
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| creamy bready bread crust |
Taste Description:
| creamy bready |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents |
Recommendation for 6-acetyl-1,2,3,4-tetrahydropyridine usage levels up to: | | not for fragrance use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
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For Odor |
No odor group found for these |
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(R)- | strawberry furanone | FL/FR |
(S)- | strawberry furanone | FL/FR |
acidic |
| cyclohexyl acetic acid | FL/FR |
balsamic |
2- | acetyl furan | FL/FR |
iso | amyl pyruvate | FL/FR |
bready |
| coffee furanone | FL/FR |
| furfural | FL/FR |
| rum ether | FL/FR |
buttery |
| acetoin | FL/FR |
| acetyl butyryl | FL/FR |
| acetyl propionyl | FL/FR |
3,4- | hexane dione | FL/FR |
iso | amyl levulinate | FL/FR |
2-oxo | butyric acid | FL/FR |
| caramel furanone solution | FL/FR |
| caramel pentadione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| ethyl cyclopentenolone | FL/FR |
| ethyl furaneol | FL/FR |
| ethyl maltol | FL/FR |
5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
3- | ethyl-4-methyl cyclotene | FL/FR |
| fenugreek absolute | FL/FR |
| fenugreek oleoresin | FL/FR |
| immortelle absolute | FL/FR |
| levulinic acid | FL/FR |
| maltol | FL/FR |
| maltyl isobutyrate | FL/FR |
| maltyl propionate | FL/FR |
| maple furanone | FL/FR |
| menthone lactone | FL/FR |
5- | methyl furfural | FL/FR |
iso | propenyl pyrazine | FL/FR |
| rosefuran | FL/FR |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| strawberry furanone acetate | FL/FR |
| strawberry furanone solution | FL/FR |
| toffee furanone | FL/FR |
2,6- | dimethyl pyrazine | FL/FR |
2- | methyl butyraldehyde | FL/FR |
coconut |
gamma- | heptalactone | FL/FR |
creamy |
gamma- | butyrolactone | FL/FR |
ethereal |
| ethyl 4-pentenoate | FL/FR |
| ethyl pyruvate | FL/FR |
fermented |
| amyl alcohol | FL/FR |
| butyl laevo-lactate | FL/FR |
| ethyl (E)-2-crotonate | FL/FR |
| ethyl crotonate | FL/FR |
| valeraldehyde | FL/FR |
floral |
| phenethyl alcohol | FL/FR |
fruity |
iso | butyl 2-butenoate | FL/FR |
| cherry propanol | FL/FR |
| ethyl lactate | FL/FR |
(E)- | ethyl tiglate | FL/FR |
| hexyl (E)-tiglate | FL/FR |
| maltyl acetate | FL/FR |
| methyl nonane dione | FL/FR |
2- | pentyl furan | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
green |
iso | amyl 3-(2-furan) propionate | FL/FR |
herbal |
| butyl levulinate | FL/FR |
white | cognac oil | FL/FR |
meaty |
| sulfurol | FL/FR |
| sulfuryl acetate | FL/FR |
minty |
dextro- | carvone | FL/FR |
musty |
2- | acetyl pyrrole | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
nutty |
2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
2- | acetyl-5-methyl furan | FL/FR |
3,5- | cocoa pyrazine | FL/FR |
1,2- | cyclohexane dione | FL/FR |
2,3- | dimethyl pyrazine | FL/FR |
| filbert pyrazine | FL/FR |
2,6- | lutidine | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
phenolic |
4- | methyl-2,6-dimethoxyphenol | FL/FR |
popcorn |
2- | acetyl pyrazine | FL/FR |
2- | acetyl pyridine | FL/FR |
spicy |
| caraway seed oleoresin | FL/FR |
(E)- | propyl 2-furan acrylate | FL/FR |
| spicy acetoacetate | FL/FR |
(E)- | tiglic acid | FL/FR |
sweet |
| vanilla oleoresin bali | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla oleoresin bourbon | FL/FR |
| vanillin | FL/FR |
| vanillyl isobutyrate | FL/FR |
| tetrahydrofurfuryl alcohol | FL/FR |
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For Flavor |
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No flavor group found for these |
4- | acetyl-2,5-dimethyl-3(2H)-furanone | FL |
2- | acetyl-3,4,5,6-tetrahydropyridine | FL |
(E)- | aconitic acid | FL |
| allyl 2-furoate | FL |
iso | amyl levulinate | FL/FR |
iso | amyl pyruvate | FL/FR |
| benzyl disulfide | FL |
1,2- | cyclohexane dione | FL/FR |
2,5- | diethyl tetrahydrofuran | FL |
alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| ethyl 4-pentenoate | FL/FR |
5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
3- | ethyl-4-methyl cyclotene | FL/FR |
| furfuryl acetone | FL |
| menthone lactone | FL/FR |
| methyl nonane dione | FL/FR |
| rosefuran | FL/FR |
(R)- | strawberry furanone | FL/FR |
(S)- | strawberry furanone | FL/FR |
| strawberry furanone ethyl ether | FL |
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iso | amyl 3-(2-furan) propionate | FL/FR |
acetic |
| formic acid | FL |
acidic |
| levulinic acid | FL/FR |
dextro,laevo- | tartaric acid | FL |
berry |
| maltyl acetate | FL/FR |
bready |
| bread crust distillate | FL |
| mango furanone | FL |
2- | propionyl thiazole | FL |
brown |
2-oxo | butyric acid | FL/FR |
| fenugreek oleoresin | FL/FR |
| furfural | FL/FR |
5- | methyl furfural | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
(E)- | tiglic acid | FL/FR |
burnt |
| furfuryl alcohol | FL |
iso | propenyl pyrazine | FL/FR |
| rum ether | FL/FR |
buttery |
| butyl laevo-lactate | FL/FR |
| diacetyl | FL |
3,4- | hexane dione | FL/FR |
caramellic |
| caramel furanone | FL |
| caramel furanone solution | FL/FR |
| caramel pentadione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
| ethyl furaneol | FL/FR |
| ethyl maltol | FL/FR |
5- | ethyl-3,4,5,6-tetramethyl cyclohexen-2-one | FL |
| fenugreek absolute | FL/FR |
| maltol | FL/FR |
| maltyl propionate | FL/FR |
| maple furanone | FL/FR |
3- | methyl butyl 2-furyl butyrate | FL |
| pyruvaldehyde | FL |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| strawberry furanone acetate | FL/FR |
| strawberry furanone solution | FL/FR |
| toffee furanone | FL/FR |
cocoa |
| butyraldehyde | FL |
coffee |
| coffee distillates | FL |
| diisoamyl thiomalate | FL |
2- | thiophene thiol | FL |
corn |
2- | acetyl pyridine | FL/FR |
2- | acetyl-2-thiazoline | FL |
creamy |
| acetoin | FL/FR |
| acetyl butyryl | FL/FR |
2- | propanoyl thiophene | FL |
fatty |
| diacetyl trimer | FL |
(E,E)-2,4- | undecadienal | FL |
2,4- | undecadienal | FL |
floral |
| phenethyl alcohol | FL/FR |
| rosa canina seed extract | FL |
fruity |
| cherry propanol | FL/FR |
| ethyl lactate | FL/FR |
(E)- | ethyl tiglate | FL/FR |
| furfuryl valerate | FL |
2- | pentanoyl furan | FL |
banana cream | pie flavor | FL |
(E)- | propyl 2-furan acrylate | FL/FR |
fusel |
| amyl alcohol | FL/FR |
white | cognac oil | FL/FR |
2- | methyl butyraldehyde | FL/FR |
green |
iso | butyl 2-butenoate | FL/FR |
| hexyl (E)-tiglate | FL/FR |
| immortelle absolute | FL/FR |
2- | pentyl furan | FL/FR |
herbal |
| butyl levulinate | FL/FR |
5- | hydroxymethyl furfural | FL |
jammy |
| ethyl cyclopentenolone | FL/FR |
| maltyl isobutyrate | FL/FR |
lactonic |
gamma- | heptalactone | FL/FR |
malty |
| hordeum vulgare extract (cereal grass) | FL |
| malt distillates | FL |
meaty |
| sulfurol | FL/FR |
| sulfuryl acetate | FL/FR |
metallic |
2,5- | dihydroxy-1,4-dithiane | FL |
milky |
gamma- | butyrolactone | FL/FR |
minty |
dextro- | carvone | FL/FR |
molasses |
| molasses blackstrap | FL |
musty |
| ethyl (E)-2-crotonate | FL/FR |
nutty |
2- | acetyl furan | FL/FR |
2- | acetyl pyrrole | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
2- | acetyl-5-methyl furan | FL/FR |
| aconitic acid | FL |
3,5- | cocoa pyrazine | FL/FR |
| coffee furanone | FL/FR |
2,6- | dimethyl pyrazine | FL/FR |
2,3- | dimethyl pyrazine | FL/FR |
| filbert pyrazine | FL/FR |
2,6- | lutidine | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
| peanut oxazole | FL |
| tetrahydrofurfuryl alcohol | FL/FR |
phenolic |
4- | methyl-2,6-dimethoxyphenol | FL/FR |
roasted |
| acer spicatum bark extract | FL |
2- | acetyl pyrazine | FL/FR |
rummy |
| ethyl crotonate | FL/FR |
| ethyl pyruvate | FL/FR |
smoky |
dextro- | xylose | FL |
spicy |
| caraway seed oleoresin | FL/FR |
| spicy acetoacetate | FL/FR |
sweet |
| acetone alcohol | FL |
| caramel dione | FL |
| cyclohexyl acetic acid | FL/FR |
| honey distillates | FL |
dextro- | sorbitol | FL |
| sugar distillates | FL |
| vanilla oleoresin bali | FL/FR |
toasted |
| acetyl propionyl | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla oleoresin bourbon | FL/FR |
| vanillin | FL/FR |
| vanillyl isobutyrate | FL/FR |
waxy |
| furfuryl octanoate | FL |
| octyl 2-furoate | FL |
winey |
| valeraldehyde | FL/FR |
yeasty |
| faex extracts | FL |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | acetyl-1,4,5,6-tetrahydropyridine | | ethanone, 1-(1,4,5,6-tetrahydro-2-pyridinyl)- | | pyridine, 2-acetyl-1,4,5,6-tetrahydro- | 1-(1,4,5,6- | tetrahydro-2-pyridinyl) ethanone | 1-(1,4,5,6- | tetrahydropyridin-2-yl)ethanone | 1-(1,2,3,4- | tetrahydropyridin-6-yl)ethanone |
Articles:
PubMed: | New short and general synthesis of three key Maillard flavour compounds: 2-Acetyl-1-pyrroline, 6-acetyl-1,2,3,4-tetrahydropyridine and 5-acetyl-2,3-dihydro-4H-1,4-thiazine. |
PubMed: | Stabilization of the potent odorant 2-acetyl-1-pyrroline and structural analogues by complexation with zinc halides. |
PubMed: | Chemistry of 2-acetyl-1-pyrroline, 6-acetyl-1,2,3,4-tetrahydropyridine, 2-acetyl-2-thiazoline, and 5-acetyl-2,3-dihydro-4H-thiazine: extraordinary Maillard flavor compounds. |
PubMed: | An expeditious, high-yielding construction of the food aroma compounds 6-acetyl-1,2,3,4-tetrahydropyridine and 2-acetyl-1-pyrroline. |
PubMed: | Elucidation of tautomer structures of 2-acetyltetrahydropyridine using gas chromatography/mass spectrometry and gas chromatography/infrared spectroscopy. |
PubMed: | Detailed investigation of the production of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine in proline/1,3-dihydroxyacetone model systems. |
PubMed: | Formation of odorants in Maillard model systems based on l-proline as affected by pH. |
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