Articles:
| PubMed: | Identification of 2-ethyl-4-methyl-3-thiazoline and 2-isopropyl-4-methyl-3-thiazoline for the first time in nature by the comprehensive analysis of sesame seed oil. |
thiazole, 2,5-dihydro-4-methyl-2-(1-methylethyl)-
Notes:
None found
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Chemical sources Association Inc Exchange of knowledge Need This Item for Flavor? You can contact the Chemical Sources Association. Events Links Product(s):
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| CAS Number: | 67936-13-4 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 267-816-9 | |
| FDA UNII: | 35Q7TX396D | |
| Nikkaji Web: | J317.237F | |
| XlogP3-AA: | 1.90 (est) | |
| Molecular Weight: | 143.25261000 | |
| Formula: | C7 H13 N S | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: flavor enhancers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 2206 2-isopropyl-4-methyl-3-thiazoline |
| FEMA Number: | 4767 2-isopropyl-4-methyl-3-thiazoline |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.99360 to 1.07400 @ 20.00 °C. |
| Pounds per Gallon - (est).: | 8.277 to 8.947 |
| Refractive Index: | 1.49710 to 1.54700 @ 20.00 °C. |
| Boiling Point: | 201.34 °C. @ 760.00 mm Hg (est) |
| Boiling Point: | 45.00 to 46.00 °C. @ 0.75 mm Hg |
| Acid Value: | 2.00 max. KOH/g |
| Vapor Pressure: | 0.439000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 168.00 °F. TCC ( 75.60 °C. ) (est) |
| logP (o/w): | 3.381 (est) |
| Soluble in: | |
| alcohol | |
| water, 61.77 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: toasted | |
| Odor Strength: | high , recommend smelling in a 0.10 % solution or less |
| toasted sulfurous sweet cocoa chocolate | |
| Odor Description: at 0.10 % in propylene glycol. | toasted sulfury sweet cocoa chocolate |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the CSA |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor enhancers | ||
| Recommendation for 2-isopropyl-4-methyl-3-thiazoline usage levels up to: | |||
| not for fragrance use. | |||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 26 | |||
| Click here to view publication 26 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 0.25000 | 0.50000 | |
| beverages(nonalcoholic): | 0.25000 | 0.50000 | |
| beverages(alcoholic): | 0.25000 | 0.50000 | |
| breakfast cereal: | 0.25000 | 0.50000 | |
| cheese: | - | - | |
| chewing gum: | 0.50000 | 1.00000 | |
| condiments / relishes: | 0.25000 | 0.50000 | |
| confectionery froastings: | 0.25000 | 0.50000 | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | 0.25000 | 0.50000 | |
| fruit ices: | 0.25000 | 0.50000 | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | 0.25000 | 0.50000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | 0.25000 | 0.50000 | |
| meat products: | - | - | |
| milk products: | 0.25000 | 0.50000 | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | 0.25000 | 0.50000 | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | 0.25000 | 0.50000 | |
| snack foods: | - | - | |
| soft candy: | 0.25000 | 0.50000 | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | 0.25000 | 0.50000 | |
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 3017811 |
| National Institute of Allergy and Infectious Diseases: | Data |
| 4-methyl-2-propan-2-yl-2,5-dihydro-1,3-thiazole | |
| Chemidplus: | 0067936134 |
References:
| 4-methyl-2-propan-2-yl-2,5-dihydro-1,3-thiazole | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 3017811 |
| Pubchem (sid): | 135247747 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
| For Odor | ||
| chocolate | ||
| chocolate | ||
| chocolate pyrazine A | FL/FR | |
| 2- | methoxypyrazine | FL/FR |
| cocoa | ||
| 2-iso | butyl-3,5-(and 3,6)-dimethyl pyrazine | FL/FR |
| honey | ||
| butyl phenyl acetate | FL/FR | |
| sulfurous | ||
| cocoa essence | FL/FR | |
| sweet | ||
| vanilla oleoresin bali | FL/FR | |
| For Flavor | ||
| No flavor group found for these | ||
| 2-iso | butyl-3,5-(and 3,6)-dimethyl pyrazine | FL/FR |
| chocolate pyrazine A | FL/FR | |
| 2- | methoxypyrazine | FL/FR |
| 3- | mercapto-3-methyl-1-butyl acetate | FL |
| alliaceous | ||
| shallot oil | FL | |
| chocolate | ||
| cocoa essence | FL/FR | |
| honey | ||
| butyl phenyl acetate | FL/FR | |
| sweet | ||
| vanilla oleoresin bali | FL/FR | |
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| found in nature |
Synonyms:
| 2,5- | dihydro-2-isopropyl-4-methyl thiazole |
| 2,5- | dihydro-2-isopropyl-4-methylthiazole |
| 4- | methyl-2-propan-2-yl-2,5-dihydro-1,3-thiazole |
| 2-iso | propyl-4-methyl-2,5-dihydrothiazole |
| thiazole, 2,5-dihydro-4-methyl-2-(1-methylethyl)- |