Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 92.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 49.00 to 52.00 °C. @ 760.00 mm Hg
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Boiling Point: | 367.00 to 368.00 °C. @ 760.00 mm Hg
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Flash Point: | 245.00 °F. TCC ( 118.33 °C. )
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logP (o/w): | 6.790 (est) |
Soluble in: |
| alcohol | | water, 0.03955 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for manool usage levels up to: | | not for fragrance use.
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Recommendation for manool flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
| 5-(5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-methylpent-1-en-3-ol |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 238792 |
Pubchem (sid): | 135217579 |
Pherobase: | View |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
(1S-(1alpha(S*), 4abeta,8aalpha))-alpha- | ethenyl decahydro-alpha,5,5,8a-tetramethyl-2-methylene-1-naphthalene propanol | (13R)- | labda-8(20),14-dien-13-ol | | labda-8(20),14-dien-13-ol, (13R)- | | labda-8(20),14-dien-13-ol, (13S)- | 3- | methyl-5-(5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-yl)-pent-1-en-3-ol | 3- | methyl-5-(5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl)pent-1-en-3-ol | 1- | naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, [1S-[1.alpha.(R*),4a.beta.,8a.alpha.]]- | 1- | naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4a.beta.,8a.alpha.]]- | 1- | naphthalenepropanol, a-ethenyldecahydro-a,5,5,8a-tetramethyl-2-methylene- | 1- | naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene- | 1- | naphthalenepropanol,5,5,8a-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4a.beta.,8a.alpha.]]- | 5-(5,5,8a- | trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-methylpent-1-en-3-ol |
Articles:
PubMed: | Synthesis and biological evaluation of ( - )-13,14-dihydroxy-8,11,13-podocarpatrien-7-one and derivatives from (+)-manool. |
PubMed: | Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. |
PubMed: | Chemical constituents of Abies delavayi. |
PubMed: | Facile access to optically active ring C aromatic diterpene derivatives from (+)-manool. first synthesis of 13,14-dihydroxy8,11,13-podocarpatrien-7-one. |
PubMed: | Terpenes From the Root of Salvia hypoleuca Benth. |
PubMed: | Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture. |
PubMed: | (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho-[2,1-c]pyran (Pyamber). |
PubMed: | Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents. |
PubMed: | Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria. |
PubMed: | Isolation and identification of ligands for the goldfish testis androgen receptor in chemical recovery condensates from a Canadian bleached kraft pulp and paper mill. |
PubMed: | Biota: sediment partitioning of aluminium smelter related PAHs and pulp mill related diterpenes by intertidal clams at Kitimat, British Columbia. |
PubMed: | Substrate specificity of Rv3378c, an enzyme from Mycobacterium tuberculosis, and the inhibitory activity of the bicyclic diterpenoids against macrophage phagocytosis. |
PubMed: | Influence of ionic interactions on essential oil and phenolic diterpene composition of Dalmatian sage (Salvia officinalis L.). |
PubMed: | Chemical composition and antimicrobial activity of the essential oils from Cleome spinosa. |
PubMed: | Chemical composition of endemic Scorzonera sandrasica and studies on the antimicrobial activity against multiresistant bacteria. |
PubMed: | Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2. |
PubMed: | Antiproliferative activity of Greek propolis. |
PubMed: | Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. |
PubMed: | Variations in essential oil, phenolic compounds, and antioxidant activity of tunisian cultivated Salvia officinalis L. |
PubMed: | Synthesis and antimalarial activities of optically active labdane-type diterpenes. |
PubMed: | Terpenoid constituents of Abies chensiensis with potential anti-inflammatory activity. |
PubMed: | Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry. |
PubMed: | Assessment of some diterpenoids in commercial distilled gin. |
PubMed: | Transformations of manool. tri- and tetracyclic norditerpenoids with in vitro activity against Plasmodium falciparum. |
PubMed: | Chemical composition and antimicrobial activity of volatile components from capitula and aerial parts of Rhaponticum acaule DC growing wild in Tunisia. |
PubMed: | (+)-agelasine D: improved synthesis and evaluation of antibacterial and cytotoxic activities. |
PubMed: | Facile access to optically active labdane-type diterpenes from (+)-manool. Synthesis of (+)-coronarin E, (+)-15,16-epoxy-8(17),13(16),14-labdatriene, and (+)-labda-8(17),13(Z)-diene-15,16-diol. |
PubMed: | Effect of nitrogen concentration of the nutrient solution on the volatile constituents of leaves of Salvia fruticosa Mill. in solution culture. |
PubMed: | The propolis of stingless bees: terpenes from the tibia of three Frieseomelitta species. |
PubMed: | Essential oils produced by in vitro shoots of sage (Salvia officinalis L.). |
PubMed: | [Chemical constituents from Speranskia tuberculata (Bge.) Baill]. |
PubMed: | Dynamics of yield components and essential oil production in a commercial hybrid sage (Salvia officinalis x Salvia fruticosa cv. Newe Ya'ar no. 4). |
PubMed: | Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity. |
PubMed: | Konishiol, a new sesquiterpene, and bioactive components from Cunninghamia konishii. |
PubMed: | Diterpenes from Solidago rugosa. |
PubMed: | Terpenoids from Salvia sclarea. |
PubMed: | Synthesis of manool-related labdane diterpenes as platelet aggregation inhibitors. |
PubMed: | Platelet aggregation inhibitors in a Bhutanese medicinal plant, shug chher. |
PubMed: | Leaf surface chemicals fromNicotiana affecting germination ofPeronospora tabacina (adam) sporangia. |
PubMed: | Chemistry and chemical ecology of the Bahamian spongeAplysilla glacialis. |
PubMed: | Ovipositional response of tobacco budworm moths (Lepidoptera: Noctuidae) to cuticular labdanes and sucrose esters from the green leaves ofNicotiana glutinosa L. (Solanaceae). |
PubMed: | Constituents of Juniperus recurva var. squamata Oil. |
PubMed: | Allelochemical resistance of bald cypress,Taxodium distichum, heartwood to the subterranean termite,Coptotermes formosanus. |
PubMed: | Isolation of (--)-manool from the liverwort, Jungermannia torticalyx. |
PubMed: | [Not Available]. |
PubMed: | [Not Available]. |
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