Name: | glycyrrhiza glabra l. extract powder |
CAS Number: | 68916-91-6 |
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Other(deleted CASRN): | 8008-94-4 |
ECHA EC Number: | 272-837-1 |
Category: cosmetic, flavor and fragrance agents, dietary supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Food Chemicals Codex Listed: | No |
Organoleptic Properties:
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Odor Type: licorice |
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| licorice |
Odor Description: at 100.00 %. | licorice |
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Flavor Type: licorice |
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| licorice |
Taste Description:
| licorice |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
AuNutra® Industries |
Licorice P.E.
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BOC Sciences |
For experimental / research use only. |
Licorice Extract 10:1
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Chemical-navi - Nikkol |
POLYOL SOLUBLE LICORICE EXTRACT BG100
Odor: characteristic Use: Licorice extract with Glabidin content 0.4%.
Use for whitening, anti-oxidant, anti-tyrosinase, anti-microbial and SOD-like activity. |
ECSA Chemicals |
EXTRAIT DE LIQUORICE BIO EN POUDRE
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ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
Excellentia International |
Licorice Extract
|
Frutarom |
LICORICE SE
KOSHER Flavor: Sweet, dark, astringent, dark, rooty, metallic |
Global Essence |
Licorice Extract
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H. Interdonati, Inc. |
Licorice extract (Glycyrrhiza spp.)
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Featured Products |
Horner International |
Licorice Extract
|
IFF |
LICORICE SE
KOSHER Flavor: Sweet, dark, astringent, dark, rooty, metallic |
Naturex |
Licorice Extract
NAT healthy™ |
OQEMA |
Licorice Extract
|
Penta International |
LICORICE ROOT FLUID EXTRACT
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Synthite Industries |
Licorice Extract
|
E-books and Brochures |
Vege Tech |
Organic Licorice Extract
|
Vevy Europe |
LIQUIRITINA
Odor: characteristic Use: antiphlogistic and antifermentation activity; aromatising. |
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-man TDLo 209000 mg/kg/2Y-I BEHAVIORAL: MUSCLE WEAKNESS
CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE Italian Journal of Neurological Sciences. Vol. 4, Pg. 493, 1983.
intraperitoneal-mouse LD50 1500 mg/kg BLOOD: CHANGES IN SPLEEN
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
oral-mouse LD50 > 7500 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
intraperitoneal-rat LD50 1420 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: OTHER CHANGES Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
oral-rat LD50 14200 mg/kg KIDNEY, URETER, AND BLADDER: OTHER CHANGES
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
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Dermal Toxicity: |
subcutaneous-mouse LD50 4000 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BLOOD: CHANGES IN SPLEEN Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
subcutaneous-rat LD50 4200 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: OTHER CHANGES Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Safety References:
References:
| glycyrrhiza glabra l. extract powder |
Pubchem (sid): | 135314590 |
Other Information:
FDA Substances Added to Food (formerly EAFUS): | View |
FDA Listing of Food Additive Status: | View |
MedlinePlusSupp: | View |
Wikipedia: | View |
Potential Blenders and core components note
|
For Odor |
No odor group found for these |
4- | methyl-2-(1-methyl-1-butenyl)-1,3-dioxolane | |
anise |
alpha- | allyl-4-methyl-3-cyclohexene methanol | |
| anise oleoresin | FL/FR |
| anise seed absolute | FL/FR |
| anise seed concrete | FR |
| anise seed oil | FL/FR |
star | anise seed oil china | FL/FR |
| anise seed oil colombia | FL/FR |
star | anise seed oil spain | FL/FR |
star | anise seed oil terpeneless | FL/FR |
| anise seed tincture | FL/FR |
sweet | fennel absolute | FL/FR |
sweet | fennel oleoresin | FL/FR |
sweet | fennel seed oil | FL/FR |
| foeniculum vulgare fruit extract | FL/FR |
| foeniculum vulgare mill. var. dulce d.c. fruit extract | FL/FR |
| glycyrrhiza glabra rhizome/root | CS |
| glycyrrhiza glabra root | CS |
| licorice concrete | FR |
| pimpinella anisum seed extract | FL/FR |
anisic |
(Z)- | anethol | |
para- | anisyl propanal | FR |
| dihydroanethol | FL/FR |
| estragole | FL/FR |
| ethyl para-anisate | FL/FR |
| ocimum basilicum herb oil egypt | FL/FR |
| ocimum basilicum leaf oil CO2 extract | FL/FR |
| ocimum basilicum leaf oil india | FL/FR |
| sassafras acetate | FL/FR |
caramellic |
| caramel pentadione | FL/FR |
| mesitene lactone | FR |
floral |
2,4- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
4,6- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
| methyl ionyl acetate | FL/FR |
beta- | ocimene | FL/FR |
fruity |
iso | butyl 2-butenoate | FL/FR |
(E,E)- | ethyl sorbate | FL/FR |
| fruity ketal | FL/FR |
| hexanal propylene glycol acetal | FL/FR |
herbal |
| tricyclo(5.2.1.02,6)dec-3-enyl acetate | FR |
licorice |
(E)- | anethol | FL/FR |
| anethol | FL/FR |
sweet | basil oleoresin | FL/FR |
| glycyrrhiza glabra rhizome/root extract | FL/FR |
| glycyrrhiza glabra root extract | FL/FR |
| glycyrrhiza glabra root tincture | FL/FR |
| glycyrrhiza uralensis root oil CO2 extract | FL/FR |
| licorice absolute | FL/FR |
| licorice fragrance | FR |
| licorice infusions | FL/FR |
| licorice oil | FL/FR |
| licorice root oil | FL/FR |
| ocimum basilicum | |
| ocimum basilicum herb oil poland | FL/FR |
| ocimum basilicum herb oil vietnam | FL/FR |
| ocimum basilicum leaf oil | FL/FR |
| ocimum basilicum leaf oil terpeneless | FL/FR |
minty |
bitter | fennel flower oil lithuania | |
bitter | fennel seed oil (foeniculum vulgare capillaceum) | FR |
bitter | fennel seed oil lithuania | CS |
| foeniculum vulgare capillaceum fruit extract | FR |
musk |
omega- | pentadecalactone | FL/FR |
musty |
2- | acetyl pyrrole | FL/FR |
powdery |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
| tarragon | |
| tarragon oil replacer | FL/FR |
sweet |
2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | FL/FR |
waxy |
| waxy acetate | FR |
|
For Flavor |
|
No flavor group found for these |
| anethol | FL/FR |
(Z)- | anethol | |
bitter | fennel flower oil lithuania | |
| fleabane oil (erigeron canadensis) | FL |
2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | FL/FR |
anise |
alpha- | allyl-4-methyl-3-cyclohexene methanol | |
(E)- | anethol | FL/FR |
| anise oleoresin | FL/FR |
| anise seed absolute | FL/FR |
| anise seed oil | FL/FR |
star | anise seed oil china | FL/FR |
| anise seed oil colombia | FL/FR |
star | anise seed oil spain | FL/FR |
star | anise seed oil terpeneless | FL/FR |
| anise seed tincture | FL/FR |
| ethyl para-anisate | FL/FR |
sweet | fennel absolute | FL/FR |
sweet | fennel oleoresin | FL/FR |
sweet | fennel seed oil | FL/FR |
| foeniculum vulgare fruit extract | FL/FR |
| foeniculum vulgare mill. var. dulce d.c. fruit extract | FL/FR |
4- | methyl-2-(1-methyl-1-butenyl)-1,3-dioxolane | |
| pimpinella anisum seed extract | FL/FR |
anisic |
| ocimum basilicum herb oil egypt | FL/FR |
caramellic |
| caramel pentadione | FL/FR |
floral |
2,4- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
4,6- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
fruity |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
| ethyl 3-oxohexanoate | FL |
(E,E)- | ethyl sorbate | FL/FR |
| fruity ketal | FL/FR |
| furfuryl isovalerate | FL |
| hexanal propylene glycol acetal | FL/FR |
(E,E)- | methyl sorbate | FL |
green |
iso | butyl 2-butenoate | FL/FR |
beta- | ocimene | FL/FR |
herbal |
| dihydroanethol | FL/FR |
| ocimum basilicum leaf oil CO2 extract | FL/FR |
| ocimum basilicum leaf oil india | FL/FR |
licorice |
| anise flavor | FL |
| anise orange flavor | FL |
sweet | basil oleoresin | FL/FR |
| estragole | FL/FR |
| glycyrrhiza glabra rhizome/root extract | FL/FR |
| glycyrrhiza glabra root extract | FL/FR |
| glycyrrhiza glabra root extract powder | FL |
| glycyrrhiza glabra root tincture | FL/FR |
| glycyrrhiza uralensis root oil CO2 extract | FL/FR |
| licorice absolute | FL/FR |
| licorice flavor | FL |
black | licorice flavor | FL |
red | licorice flavor | FL |
| licorice infusions | FL/FR |
| licorice oil | FL/FR |
| licorice root oil | FL/FR |
| ocimum basilicum | |
| ocimum basilicum herb oil poland | FL/FR |
| ocimum basilicum herb oil vietnam | FL/FR |
| ocimum basilicum leaf oil | FL/FR |
| ocimum basilicum leaf oil terpeneless | FL/FR |
nutty |
2- | acetyl pyrrole | FL/FR |
spicy |
| tarragon | |
| tarragon oil replacer | FL/FR |
tarragon |
| sassafras acetate | FL/FR |
vanilla |
omega- | pentadecalactone | FL/FR |
woody |
| methyl ionyl acetate | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| extract from the dried rhizomes and roots of the licorice, glycyrrhiza glabra l., leguminosae | | glycyrrhiza glabra extract powder | | licorice extract powder (glycyrrhiza glabra l.) | | licorice P.E. | | liquiritina (Vevy) | | polyol soluble licorice extract BG100 | | yang gan cao extract |
Articles:
PubMed: | Effect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal. |
PubMed: | Synergy of Licorice Extract and Pea Protein Hydrolysate for Oxidative Stability of Soybean Oil-in-Water Emulsions. |
PubMed: | Glabridin induces glucose uptake via the AMP-activated protein kinase pathway in muscle cells. |
PubMed: | Quality enhancement in the Japanese sea bass (Lateolabrax japonicas) fillets stored at 4°C by chitosan coating incorporated with citric acid or licorice extract. |
PubMed: | Topically applied glycyrrhizic acid causes hair removal in rats. |
PubMed: | 18β-glycyrrhetinic acid attenuates anandamide-induced adiposity and high-fat diet induced obesity. |
PubMed: | Special licorice extracts containing lowered glycyrrhizin and enhanced licochalcone a prevented Helicobacter pylori-initiated, salt diet-promoted gastric tumorigenesis. |
PubMed: | [Adverse reaction induced by licorice preparations: clinical analysis of 93 cases]. |
PubMed: | Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis. |
PubMed: | The effect of adjunctive low-dose doxycycline and licorice therapy on gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis. |
PubMed: | 18β-glycyrrhetinic acid induces UDP-glucuronosyltransferase in rats. |
PubMed: | Identification of key licorice constituents which interact with cytochrome P450: evaluation by LC/MS/MS cocktail assay and metabolic profiling. |
PubMed: | Inhibition of lipid oxidation and rancidity in precooked pork patties by radical-scavenging licorice (Glycyrrhiza glabra) extract. |
PubMed: | Natural ingredients for darker skin types: growing options for hyperpigmentation. |
PubMed: | Synergistic inhibition of lipid oxidation by pea protein hydrolysate coupled with licorice extract in a liposomal model system. |
PubMed: | CDK2 and mTOR are direct molecular targets of isoangustone A in the suppression of human prostate cancer cell growth. |
PubMed: | Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. |
PubMed: | The inhibitory effect of roasted licorice extract on human metastatic breast cancer cell-induced bone destruction. |
PubMed: | Licorice abuse: time to send a warning message. |
PubMed: | Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice. |
PubMed: | Analytical strategy to reveal the in vivo process of multi-component herbal medicine: a pharmacokinetic study of licorice using liquid chromatography coupled with triple quadrupole mass spectrometry. |
PubMed: | Licorice extract a sweet way to control decay. |
PubMed: | Carbendazim-induced testicular damage and oxidative stress in albino rats: ameliorative effect of licorice aqueous extract. |
PubMed: | Licorice extract a sweet way to control decay. |
PubMed: | Effects of Space Flight on the Chemical Constituents and Anti-Inflammatory Activity of Licorice (Glycyrrhiza uralensis Fisch). |
PubMed: | Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice. |
PubMed: | Analysis of the synergistic effect of glycyrrhizin and other constituents in licorice extract on lipopolysaccharide-induced nitric oxide production using knock-out extract. |
PubMed: | Hepatoprotective and antioxidant effects of licorice extract against CCl₄-induced oxidative damage in rats. |
PubMed: | Liquiritigenin decreases selective molecular and behavioral effects of cocaine in rodents. |
PubMed: | Licorice extract increases cyclophosphamide teratogenicity by upregulating the expression of cytochrome P-450 2B mRNA. |
PubMed: | Isoliquiritigenin from licorice root suppressed neovascularisation in experimental ocular angiogenesis models. |
PubMed: | Effect of licorice extract on the complications of diabetes nephropathy in rats. |
PubMed: | Factors influencing glabridin stability. |
PubMed: | Solid-phase extraction of liquiritin and glycyrrhizin from licorice using porous alkyl-pyridinium polymer sorbent. |
PubMed: | Top 10 botanical ingredients in 2010 anti-aging creams. |
PubMed: | Isoangustone A present in hexane/ethanol extract of Glycyrrhiza uralensis induces apoptosis in DU145 human prostate cancer cells via the activation of DR4 and intrinsic apoptosis pathway. |
PubMed: | [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. |
PubMed: | Rapid identification and preparative isolation of antioxidant components in licorice. |
PubMed: | Control of downy mildew (Pseudoperonospora cubensis) of greenhouse grown cucumbers with alternative biological agents. |
PubMed: | Analysis of phenolic and triterpenoid compounds in licorice and rat plasma by high-performance liquid chromatography diode-array detection, time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry. |
PubMed: | Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. |
PubMed: | Purification of flavonoids and triterpene saponins from the licorice extract using preparative HPLC under RP and HILIC mode. |
PubMed: | Inhibitory effects of isoliquiritigenin and licorice extract on voltage-dependent K(+) currents in H9c2 cells. |
PubMed: | Licorice preparations improve efficiency of chemotherapy and surgical treatment of transplanted tumors. |
PubMed: | The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis. |
PubMed: | A licorice extract reduces lipopolysaccharide-induced proinflammatory cytokine secretion by macrophages and whole blood. |
PubMed: | Artocarpus lakoocha heartwood extract as a novel cosmetic ingredient: evaluation of the in vitro anti-tyrosinase and in vivo skin whitening activities. |
PubMed: | HILIC for separation of co-eluted flavonoids under RP-HPLC mode. |
PubMed: | A time course analysis of systemic administration of aqueous licorice extract on spatial memory retention in rats. |
PubMed: | Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract. |
PubMed: | Licorice extract does not impair the male reproductive function of rats. |
PubMed: | Skin lightening preparations and the hydroquinone controversy. |
PubMed: | Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. |
PubMed: | [Properties of commercial licorice extracts used as a food additive]. |
PubMed: | Isoliquiritigenin, one of the antispasmodic principles of Glycyrrhiza ularensis roots, acts in the lower part of intestine. |
PubMed: | High levels of ochratoxin A in licorice and derived products. |
PubMed: | The effect of liquorice extract-containing starch gel on the amount and microbial composition of plaque. |
PubMed: | Licorice: a possible anti-inflammatory and anti-ulcer drug. |
PubMed: | The application of macroporous resins in the separation of licorice flavonoids and glycyrrhizic acid. |
PubMed: | Toxicologic evaluation of licorice extract as a cigarette ingredient. |
PubMed: | Glabridin, an isoflavan from licorice root, inhibits inducible nitric-oxide synthase expression and improves survival of mice in experimental model of septic shock. |
PubMed: | Topical agents used in the management of hyperpigmentation. |
PubMed: | Comparison of antioxidant activity of extract from roots of licorice (Glycyrrhiza glabra L.) to commercial antioxidants in 2% hydroquinone cream. |
PubMed: | The treatment of atopic dermatitis with licorice gel. |
PubMed: | Source of arsenic in licorice confectionery products. |
PubMed: | Determination of low levels of methanol and ethanol in licorice extract by large volume injection head-space GC. |
PubMed: | Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. |
PubMed: | Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells. |
PubMed: | Anti-Helicobacter pylori flavonoids from licorice extract. |
PubMed: | Effects of raw materials, ingredients, and production lines on arsenic and copper concentrations in confectionery products. |
PubMed: | Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. |
PubMed: | Estrogen-like activity of glabrene and other constituents isolated from licorice root. |
PubMed: | Isolation and identification of main constituents in an enzymatically hydrolysed licorice extract sweetener. |
PubMed: | Constituents and their sweetness of food additive enzymatically modified licorice extract. |
PubMed: | [State of pulmonary metabolism during radiotherapy of thoracic neoformations and possibilities of its correction]. |
PubMed: | The inhibitory effect of glabridin from licorice extracts on melanogenesis and inflammation. |
PubMed: | Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: in vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice. |
PubMed: | [Properties of glycyrrhizin in Kampo extracts including licorice root and changes in the blood concentration of glycyrrhetic acid after oral administration of Kampo extracts]. |
PubMed: | [The choleretic effects of licorice: identification and determination of the pharmacologically active components of Glycyrrhiza glabra]. |
PubMed: | Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. |
PubMed: | My engagement with steroids: a review. |
PubMed: | HPLC determination of glycyrrhizin and glycyrrhetic acid in biological fluids, after licorice extract administration to humans and rats. |
PubMed: | Bioavailability of glycyrrhizin and licorice extract in rat and human plasma as detected by a HPLC method. |
PubMed: | Giant negative U waves in a patient with uncontrolled hypertension and severe hypokalemia. |
PubMed: | Effect of dietary soybean and licorice on the male F344 rat: an integrated study of some parameters relevant to cancer chemoprevention. |
PubMed: | [Studies on concentration of glycyrrhizin in plasma and its absorption after oral administration of licorice extract and glycyrrhizin]. |
PubMed: | Effect of licorice extract (Fm100) on release of secretin and exocrine pancreatic secretion in humans. |
PubMed: | Release of secretin by licorice extract in dogs. |
PubMed: | [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. Prospective study]. |
PubMed: | [Quadriplegia, severe hypokalemic alkalosis, tetany, arterial hypertension in relation to excessive licorice extract consumption in a chronic alcoholic]. |
PubMed: | [Quadriplegia with hypokalemia and metabolic alkalosis secondary to ingestion of licorice extract]. |
PubMed: | [Paralysis with hypokalemia following prolonged ingestion of licorice extract]. |
PubMed: | [A new case of severe potassium depletion caused by licorice extract]. |
PubMed: | [New case of paralysis with hypokalemia and metabolic alkalosis secondary to excessive and prolonged ingestion of licorice extract after treatment of alcoholic intoxication]. |
PubMed: | [Quadriplegia with hypokalemia and metabolic alkalosis secondary to massive and prolonged ingestion of licorice extract in an alcoholic and potomanic psychopath]. |
PubMed: | [Gastroduodenal ulcer; results obtained in treatment of 85 patients with a licorice extract]. |
PubMed: | [Critique on the use of licorice extract in the treatment of gastroduodenal ulcer]. |
PubMed: | [Treatment of gastroduodenal ulcer with a licorice extract preparation]. |
PubMed: | [Glycyrrhizin-free licorice extract]. |
PubMed: | [Licorice Extract]. |
PubMed: | [Licorice extract and glycyrrhizinic acid in therapy of Addison's disease]. |
PubMed: | [Excretion of water and electrolytes during a 24-hour period and under influence of licorice extract]. |
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