(±)-menthol
DL-menthol
 
Notes:
an alcohol produced from mint oils or prepared synthetically. Flavouring agent
  • Berjé
    • Berje Inc.
      Where the world comes to its senses
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
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      Products List: View
      Product(s):
      Menthol Racemic
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
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      Product(s):
      1490-04-6 DL-Menthol
       
Synonyms   Articles   Notes   Search
CAS Number: 1490-04-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 216-074-4
FDA UNII: L7T10EIP3A
Nikkaji Web: J2.129F
Beilstein Number: 3194263
MDL: MFCD00001484
CoE Number: 63
XlogP3-AA: 3.00 (est)
Molecular Weight: 156.26860000
Formula: C10 H20 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FEMA Number: 2665 DL-menthol
FDA:No longer provide for the use of these seven synthetic flavoring substances
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless crystallin solid (est)
Assay: 97.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 214.00 to  216.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.032000 mmHg @ 25.00 °C. (est)
Flash Point: 200.00 °F. TCC ( 93.33 °C. )
logP (o/w): 3.216 (est)
Soluble in:
 alcohol
 water, 434.5 mg/L @ 25 °C (est)
 water, 420 mg/L @ 25 °C (exp)
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Organoleptic Properties:
 
Odor Type: mentholic
 
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 
 cooling  mentholic  minty  
Odor Description:
at 10.00 % in dipropylene glycol. 
cooling mentholic minty
 
 
Flavor Type: mentholic
 
 cooling  mentholic  minty  
Taste Description:
cooling mentholic minty
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: denaturants
fragrance
refreshing agents
soothing agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Berjé
Menthol Racemic
Media
BOC Sciences
For experimental / research use only.
DL-Menthol
Mane
Menthol Racemic
Odor: Minty Aromatic Fresh
Parchem
(±)-Menthol
Sigma-Aldrich
For experimental / research use only.
(±)-Menthol
European Pharmacopoeia (EP) Reference Standard
Synonyms   Articles   Notes   Search   Top
Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 37/38 - Irritating to respiratory system and skin.
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
maximum skin levels for fine fragrances:
  0.0400 %  and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2004)
Recommendation for (±)-menthol usage levels up to:
  8.0000 % in the fragrance concentrate.
use level in formulae for use in cosmetics:
  0.2900 %
Dermal Systemic Exposure in Cosmetic Products:
 0.0074 mg/kg/day (IFRA, 2004)
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -130.00000
beverages(nonalcoholic): -35.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -1100.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -68.00000
fruit ices: -68.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -400.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 1490-04-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 1254
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 5-methyl-2-propan-2-ylcyclohexan-1-ol
Chemidplus: 0001490046
RTECS: OT0525000 for cas# 1490-04-6
Synonyms   Articles   Notes   Search   Top
References:
Leffingwell: Chirality or Article
 5-methyl-2-propan-2-ylcyclohexan-1-ol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 1490-04-6
Pubchem (cid): 1254
Pubchem (sid): 134981328
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D04849
HMDB (The Human Metabolome Database): HMDB35765
FooDB: FDB015462
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•some synthetic menthols are not chemical individuals but...mixtures of various isomers...these are designated...l-menthol, dl-menthol, l-isomenthol, d-isomenthol, dl-isomenthol, l-neomenthol, d-neomenthol, l-neoisomenthol, d-neoisomenthol and dl-neoisomenthol. •when mixed with about equal wt of camphor, chloral hydrate, phenol, or thymol, menthol forms "eutectic" mixt liquifying @ room temp. •menthol, usp drug marketed under generic name. •grades: technical; usp; fcc •synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%. synthetic menthol is also commercially available as the racemic mixture •present in cigarettes and pipe tobacco (0.1-0.45%) shaving creams, pre- and aftershave lotions (0.2-0.3%); toothpastes (0.5%); mouthwashes (1-2%); chewing gums (0.5%); cough drops (0.1%); refreshing towels (1%); rubbing alcohol (1-1.2%); and shampoos (2-0.5%) •mentholatum deep heating rub contains 5.9% menthol; mentholatum ointment, 1.35%; mentholatum deep heating lotion, 6%
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
anise
anise
 anise seed oil colombiaFL/FR
anisic
 dihydroanetholFL/FR
balsamic
 amyris wood oilFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
isobornyl acetateFL/FR
 clover nitrileFR
dextro-fenchoneFL/FR
camphoreous
 camphor tree bark oilFL/FR
fatty
 decanolFL/FR
floral
isoamyl salicylateFL/FR
 bois de rose oil brazilFL/FR
 cyclohexyl ethyl alcoholFL/FR
 geranium oil bourbonFL/FR
 heliotropyl diethyl acetalFR
alpha-hexyl cinnamaldehydeFL/FR
 ho leaf oilFR
 hyacinth etherFR
 linaloolFL/FR
laevo-linaloolFL/FR
 linalool oxideFL/FR
 methyl dihydrojasmonateFL/FR
 nerolFL/FR
 ocean propanalFL/FR
fruity
 menthyl isovalerateFL/FR
herbal
1,4-cineoleFL/FR
 eucalyptus globulus oilFL/FR
abrialis lavandin oilFL/FR
 lavender absolute bulgariaFL/FR
spike lavender oilFL/FR
 linalyl acetateFL/FR
 nopyl acetateFR
 rosemary oil spainFL/FR
mentholic
 cornmint oilFL/FR
 cornmint oil chinaFL/FR
 cornmint oil indiaFL/FR
 cornmint oil terpenelessFL/FR
dextro-neomentholFL/FR
dextro,laevo-mentholFL/FR
dextro,laevo-neomentholFL/FR
laevo-mentholFL/FR
neoisomentholFL/FR
(±)-isomenthoneFL/FR
(+)-menthoneFL/FR
laevo-menthyl acetateFL/FR
 menthyl acetateFL/FR
 menthyl acetate racemicFL/FR
 peppermint cyclohexanoneFL/FR
dextro-piperitoneFL/FR
isopulegyl acetateFL/FR
minty
laevo-carvoneFL/FR
 cornmint oil japanFL/FR
 cornmint oil terpenesFR
 dihydrocarveolFL/FR
(+)-dihydrocarvoneFL/FR
 mentha piperita extractFL/FR
 mentha piperita flower/leaf/stem extractFL/FR
 mentha piperita flower/leaf/stem waterFR
 mentha piperita herb extract americaFR
 mentha piperita leaf waterFR
 mentha piperita tinctureFL/FR
homomentholFL/FR
(±)-menthoneFL/FR
(-)-menthoneFL/FR
laevo-menthyl lactateFL/FR
2-methyl cyclohexanoneFL/FR
 methyl salicylateFL/FR
 pennyroyal oilFL/FR
 peppermint absoluteFL/FR
 peppermint distillatesFL/FR
 peppermint fragranceFR
 peppermint leafCS
 peppermint oilFL/FR
 peppermint oil americaFL/FR
 peppermint oil brazilFL/FR
 peppermint oil chinaFL/FR
 peppermint oil CO2 extractFL/FR
 peppermint oil dementholizedFL/FR
 peppermint oil englandFL/FR
 peppermint oil franceFL/FR
 peppermint oil hungaryFL/FR
 peppermint oil idahoFL/FR
 peppermint oil indiaFL/FR
 peppermint oil mongoliaFL/FR
 peppermint oil montanaFL/FR
 peppermint oil moroccoFL/FR
 peppermint oil russiaFL/FR
 peppermint oil special fractionsFL/FR
 peppermint oil tasmaniaFL/FR
 peppermint oil terpenelessFL/FR
 peppermint oil terpenesFR
 peppermint oil willametteFL/FR
 peppermint oil yakimaFL/FR
 peppermint waterFL/FR
laevo-piperitoneFL/FR
(-)-isopulegolFL/FR
isopulegolFL/FR
isopulegoneFL/FR
(R)-(+)-pulegoneFR
 spearmint oil americaFL/FR
 wintergreen oilFL/FR
 WS-23FL/FR
phenolic
 methyl benzoateFL/FR
powdery
para-anisyl alcoholFL/FR
spicy
 elettaria cardamomum seed oilFL/FR
 pepper tree berry oilFL/FR
 pimenta acris leaf oilFL/FR
terpenic
alpha-terpineolFL/FR
waxy
 decyl acetateFL/FR
woody
1,4-dimethyl bicyclo(3.2.1)octan-3-oneFR
(Z)-woody amyleneFR
 
For Flavor
 
No flavor group found for these
(+)-dihydrocarvoneFL/FR
(±)-N,N-dimethyl menthyl succinamideFL
dextro,laevo-neomentholFL/FR
neoisomentholFL/FR
3-laevo-menthoxy-2-methyl propane-1,2-diolFL
 menthyl acetate racemicFL/FR
2-methyl cyclohexanoneFL/FR
isopulegoneFL/FR
 menthyl methyl lactateFL
anise
 anise seed oil colombiaFL/FR
balsamic
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
camphoreous
 camphor tree bark oilFL/FR
citrus
laevo-linaloolFL/FR
 linaloolFL/FR
 nerolFL/FR
alpha-terpineolFL/FR
cooling
1,4-cineoleFL/FR
dextro-fenchoneFL/FR
spike lavender oilFL/FR
dextro,laevo-mentholFL/FR
isomentholFL
laevo-mentholFL/FR
 menthyl acetateFL/FR
laevo-menthyl lactateFL/FR
 peppermint oil americaFL/FR
 WS-3FL
floral
 bois de rose oil brazilFL/FR
 geranium oil bourbonFL/FR
 linalyl acetateFL/FR
 methyl dihydrojasmonateFL/FR
 ocean propanalFL/FR
fruity
para-anisyl alcoholFL/FR
 menthyl isovalerateFL/FR
green
isoamyl salicylateFL/FR
 cyclohexyl ethyl alcoholFL/FR
 dihydrocarveolFL/FR
 linalool oxideFL/FR
herbal
 dihydroanetholFL/FR
 eucalyptus globulus oilFL/FR
abrialis lavandin oilFL/FR
 lavender absolute bulgariaFL/FR
 rosemary oil spainFL/FR
mentholic
 cornmint oilFL/FR
 cornmint oil terpenelessFL/FR
dextro-neomentholFL/FR
(+)-menthoneFL/FR
 peppermint cyclohexanoneFL/FR
minty
laevo-carvoneFL/FR
 cherry menthol flavorFL
 cornmint oil chinaFL/FR
 cornmint oil indiaFL/FR
 cornmint oil japanFL/FR
 mentha piperita extractFL/FR
 mentha piperita flower/leaf/stem extractFL/FR
 mentha piperita tinctureFL/FR
homomentholFL/FR
(-)-menthoneFL/FR
(±)-menthoneFL/FR
(±)-isomenthoneFL/FR
laevo-menthyl acetateFL/FR
 methyl salicylateFL/FR
 pennyroyal oilFL/FR
 peppermint absoluteFL/FR
 peppermint distillatesFL/FR
 peppermint flavorFL
 peppermint oilFL/FR
 peppermint oil brazilFL/FR
 peppermint oil chinaFL/FR
 peppermint oil CO2 extractFL/FR
 peppermint oil dementholizedFL/FR
 peppermint oil englandFL/FR
 peppermint oil franceFL/FR
 peppermint oil hungaryFL/FR
 peppermint oil idahoFL/FR
 peppermint oil indiaFL/FR
 peppermint oil mongoliaFL/FR
 peppermint oil montanaFL/FR
 peppermint oil moroccoFL/FR
 peppermint oil russiaFL/FR
 peppermint oil special fractionsFL/FR
 peppermint oil tasmaniaFL/FR
 peppermint oil terpenelessFL/FR
 peppermint oil willametteFL/FR
 peppermint oil yakimaFL/FR
 peppermint waterFL/FR
dextro-piperitoneFL/FR
laevo-piperitoneFL/FR
isopulegolFL/FR
(-)-isopulegolFL/FR
 spearmint oil americaFL/FR
 wintergreen oilFL/FR
 WS-23FL/FR
phenolic
 methyl benzoateFL/FR
spicy
 elettaria cardamomum seed oilFL/FR
 pepper tree berry oilFL/FR
 pimenta acris leaf oilFL/FR
waxy
 decanolFL/FR
 decyl acetateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
woody
 amyris wood oilFL/FR
isobornyl acetateFL/FR
isopulegyl acetateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 cornmintFL/FR
 herbalFR
 mintFR
 peppermintFR
 spearmintFR
 wintergreenFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 basil oil sweet poland @ 1.44%
Data  GC  Search Trop  Picture
 coriander seed oil CO2 extract @ 0.70%
Data  GC  Search Trop  Picture
 cornmint oil india @ 74.51%
Data  GC  Search Trop  Picture
 fennel seed oil sweet @ trace%
Data  GC  Search Trop  Picture
 heracleum candolleanum rhizome oil india @ 0.70%
Data  GC  Search Trop  Picture
 melissa oil slovak republic @ 0.12%
Data  GC  Search Trop  Picture
 mentha longifolia (l.) huds. oil jordan @ trace%
Data  GC  Search Trop  Picture
 michelia alba flower absolute @ 0.02%
Data  GC  Search Trop  Picture
 pennyroyal oil cuba @ 0.16%
Data  GC  Search Trop  Picture
 pennyroyal oil uruguay @ 0.50-3.60%
Data  GC  Search Trop  Picture
 peppermint oil america @ 38.01%
Data  GC  Search Trop  Picture
 peppermint oil CO2 extract @ 23.80%
Data  GC  Search Trop  Picture
 peppermint oil mongolia @ 35.07%
Data  GC  Search Trop  Picture
 peppermint oil russia @ 44.46%
Data  GC  Search Trop  Picture
 pimenta leaf oil @ 0.56%
Data  GC  Search Trop  Picture
 spearmint oil america @ 0.08-0.11%
Data  GC  Search Trop  Picture
 tansy oil canada @ 0.20%
Data  GC  Search Trop  Picture
 wormseed oil spain @ 1.64%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 dermoplast
 hexahydrothymol
3-p-menthanol
3-para-menthanol
dextro,laevo-menthol
DL-menthol
 menthol racemic
5-methyl-2-(1-methyl ethyl) cyclohexanol
5-methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-isopropyl cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
2-isopropyl-5-methyl cyclohexanol
 sarna
Synonyms   Articles   Notes   Search   Top
Articles:
Info: menthol
PubMed: Patterns of longitudinal transitions in menthol use among U.S. young adult smokers.
PubMed: Formulation development and evaluation of metformin chewing gum with bitter taste masking.
PubMed: Intramolecular hydrogen transfer reaction: menthon from isopulegol.
PubMed: Formulation, preparation, and evaluation of novel orally disintegrating tablets containing taste-masked naproxen sodium granules and naratriptan hydrochloride.
PubMed: The JFFMA assessment of flavoring substances structurally related to menthol and uniquely used in Japan.
PubMed: Pharmaceutical and pharmacokinetic characterization of a novel sublingual buprenorphine/naloxone tablet formulation in healthy volunteers.
PubMed: Characterization of aroma compounds in Chinese bayberry (Myrica rubra Sieb. et Zucc.) by gas chromatography mass spectrometry (GC-MS) and olfactometry (GC-O).
PubMed: Central mechanisms of menthol-induced analgesia.
PubMed: Flavored and nonflavored smokeless tobacco products: rate, pattern of use, and effects.
PubMed: [Effects of menthol as an additive in tobacco products and the need for regulation].
PubMed: The toxic effects of cigarette additives. Philip Morris' project mix reconsidered: an analysis of documents released through litigation.
PubMed: Intake of dried bonito broth flavored with dextrin solution induced conditioned place preference in mice.
PubMed: Development of quality assessment method for optically active food flavor chemicals.
PubMed: Electrospun polyethylene oxide (PEO) nanofibers containing cyclodextrin inclusion complex.
PubMed: The health effects of menthol cigarettes as compared to non-menthol cigarettes.
PubMed: Influence of composition (CO2 and sugar) on aroma release and perception of mint-flavored carbonated beverages.
PubMed: Electrospinning of functional poly(methyl methacrylate) nanofibers containing cyclodextrin-menthol inclusion complexes.
PubMed: The menthol smoker: tobacco industry research on consumer sensory perception of menthol cigarettes and its role in smoking behavior.
PubMed: Do increases in cigarette prices lead to increases in sales of cigarettes with high tar and nicotine yields?
PubMed: Anticariogenic activity of macelignan isolated from Myristica fragrans (nutmeg) against Streptococcus mutans.
PubMed: [The role of four natures of medicine in acupoint sticking therapy].
PubMed: Enzymatic synthesis of l-menthyl alpha-maltoside and l-menthyl alpha-maltooligosides from l-menthyl alpha-glucoside by cyclodextrin glucanotransferase.
PubMed: Chemesthesis and taste: evidence of independent processing of sensation intensity.
PubMed: Characterization of measured menthol in 48 U.S. cigarette sub-brands.
PubMed: Effect of harvest time and drying method on biomass production, essential oil yield, and quality of peppermint (Mentha x piperita L.).
PubMed: Monoterpene metabolism. Cloning, expression, and characterization of menthone reductases from peppermint.
PubMed: The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes.
PubMed: Extinguishing the rewarding value of smoke cues: pharmacological and behavioral treatments.
PubMed: Identification of monomenthyl succinate, monomenthyl glutarate, and dimenthyl glutarate in nature by high performance liquid chromatography-tandem mass spectrometry.
PubMed: Flavor release and perception in hard candy: influence of flavor compound-flavor solvent interactions.
PubMed: Flavor release and perception in hard candy: influence of flavor compound-compound interactions.
PubMed: Application, function, and effects of menthol in cigarettes: a survey of tobacco industry documents.
PubMed: Crystal structure of amylose complexes with small ligands.
PubMed: Flavor release measurement by atmospheric pressure chemical ionization ion trap mass spectrometry, construction of interface and mathematical modeling of release profiles.
PubMed: A SPME-GC procedure for monitoring peppermint flavor in tablets.
PubMed: Measurements by gas chromatography/pyrolysis/mass spectrometry: fundamental conditions in (2)H/(1)H isotope ratio analysis.
PubMed: Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying.
PubMed: Effect of sucrose on the perceived flavor intensity of chewing gum.
PubMed: Glass fiber contamination of cigarette filters: an additional health risk to the smoker?
PubMed: Variation in odor thresholds for l-carvone and cineole and correlations with suprathreshold intensity ratings.
PubMed: Metabolic fate of [3H]-l-menthol in the rat.
PubMed: The alcohol-deprivation effect in hybrid mice.
PubMed: The use of flavor in cigarette substitutes.
PubMed: Comparative genotoxicity testing of mainstream whole smoke from cigarettes which burn or heat tobacco.
PubMed: The lingering question of menthol in cigarettes.
PubMed: Natural Control of Corn Postharvest Fungi Aspergillus flavus and Penicillium sp. Using Essential Oils from Plants Grown in Argentina.
PubMed: The Governor has a sweet tooth - Mouth sensing of nutrients to enhance sports performance.
PubMed: Acaricidal activity of constituents derived from peppermint oil against Tyrophagus putrescentiae.
PubMed: The tobacco endgame: It's all about behavior.
PubMed: Comparison of Soxhlet, Accelerated Solvent and Supercritical Fluid Extraction Techniques for Volatile (GC-MS and GC/FID) and Phenolic Compounds (HPLC-ESI/MS/MS) from Lamiaceae Species.
PubMed: Tobacco Products Sold by Internet Vendors Following Restrictions on Flavors and "Light" Descriptors.
PubMed: Mentha piperita essential oil induces apoptosis in yeast associated with both cytosolic and mitochondrial ROS-mediated damage.
PubMed: Switching between menthol and nonmenthol cigarettes: findings from the u.s. Cohort of the international tobacco control four country survey.
PubMed: Seasonal variability of the main components in essential oil of Mentha × piperita L.
PubMed: Public opinion about FDA regulation of menthol and nicotine.
PubMed: A rationale to design longer lasting mosquito repellents.
PubMed: Antifungal efficacy of thymol, carvacrol, eugenol and menthol as alternative agents to control the growth of food-relevant fungi.
PubMed: Antimicrobial activity of natural Respitol-B and its main components against poultry microorganisms.
PubMed: Biocontrol potential of essential oil monoterpenes against housefly, Musca domestica (Diptera: Muscidae).
PubMed: Choice alters Drosophila oviposition site preference on menthol.
PubMed: The JFFMA assessment of flavoring substances structurally related to menthol and uniquely used in Japan.
PubMed: Smoking, menthol cigarettes and all-cause, cancer and cardiovascular mortality: evidence from the National Health and Nutrition Examination Survey (NHANES) and a meta-analysis.
PubMed: Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists.
PubMed: How do international trade obligations affect policy options for obesity prevention? Lessons from recent developments in trade and tobacco control.
PubMed: Nutritional and sensory quality during refrigerated storage of fresh-cut mints (Mentha×piperita and M. spicata).
PubMed: Nematicidal activity of mint aqueous extracts against the root-knot nematode Meloidogyne incognita.
PubMed: Differential trends in cigarette smoking in the USA: is menthol slowing progress?
PubMed: FDA might consider restrictions on menthol cigarettes.
PubMed: A novel animal model of dysphagia following stroke.
PubMed: Thermal taste and anti-aspiration drugs: a novel drug discovery against pneumonia.
PubMed: The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol.
PubMed: Effect of gibberellic acid and calliterpenone on plant growth attributes, trichomes, essential oil biosynthesis and pathway gene expression in differential manner in Mentha arvensis L.
PubMed: [GC-MS study on fingerprint of volatile oil from Kadsura heteroclita].
PubMed: The effect of menthol on cigarette smoking behaviors, biomarkers and subjective responses.
PubMed: Comparison of Temperature and Additives Affecting the Stability of the Probiotic Weissella cibaria.
PubMed: Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L.
PubMed: Race moderates the effect of menthol cigarette use on short-term smoking abstinence.
PubMed: The greater effectiveness of Glomus mosseae and Glomus intraradices in improving productivity, oil content and tolerance of salt-stressed menthol mint (Mentha arvensis).
PubMed: Retention of aroma compounds from Mentha piperita essential oil by cyclodextrins and crosslinked cyclodextrin polymers.
PubMed: Menthol toxicity: an unusual cause of coma.
PubMed: Anti-yeast activity of mentha oil and vapours through in vitro and in vivo (real fruit juices) assays.
PubMed: [Therapeutic approach targeting TRP channels and development of anti-aspiration drugs].
PubMed: The distribution of transient receptor potential melastatin-8 in the rat soft palate, epiglottis, and pharynx.
PubMed: Cessation outcomes among treatment-seeking menthol and nonmenthol smokers.
PubMed: NNAL exposure by race and menthol cigarette use among U.S. smokers.
PubMed: What happens if people start drinking mouthwash as surrogate alcohol? A quantitative risk assessment.
PubMed: Response to "menthol cigarettes and lung cancer mortality".
PubMed: Characterization of aroma compounds in Chinese bayberry (Myrica rubra Sieb. et Zucc.) by gas chromatography mass spectrometry (GC-MS) and olfactometry (GC-O).
PubMed: A ban on menthol cigarettes: impact on public opinion and smokers' intention to quit.
PubMed: Irradiation depolymerized guar gum as partial replacement of gum Arabic for microencapsulation of mint oil.
PubMed: Inhibition of morphine glucuronidation in the liver microsomes of rats and humans by monoterpenoid alcohols.
PubMed: Menthol use among smokers with psychological distress: findings from the 2008 and 2009 National Survey on Drug Use and Health.
PubMed: Antioxidant and antibacterial effects of Lavandula and Mentha essential oils in minced beef inoculated with E. coli O157:H7 and S. aureus during storage at abuse refrigeration temperature.
PubMed: The relationship of neighborhood demographic characteristics to point-of-sale tobacco advertising and marketing.
PubMed: Flavored and nonflavored smokeless tobacco products: rate, pattern of use, and effects.
PubMed: Identification of aroma-active compounds in Jiashi muskmelon juice by GC-O-MS and OAV calculation.
PubMed: What would menthol smokers do if menthol in cigarettes were banned? Behavioral intentions and simulated demand.
PubMed: Menthol inhibits the proliferation and motility of prostate cancer DU145 cells.
PubMed: Mentholated cigarettes and smoking-related cancers revisited: an ecologic examination.
PubMed: Comparative GC/MS analysis of essential oils extracted by 3 methods from the bud of Citrus aurantium L. var. amara Engl.
PubMed: Intake of dried bonito broth flavored with dextrin solution induced conditioned place preference in mice.
PubMed: Stimulating oral and nasal chemoreceptors for preventing aspiration pneumonia in the elderly.
PubMed: Research opportunities concerning youth and the Family Smoking Prevention and Tobacco Control Act.
PubMed: Smoking-cessation prevalence among U.S. smokers of menthol versus non-menthol cigarettes.
PubMed: Therapeutic options for acute cough due to upper respiratory infections in children.
PubMed: Development of quality assessment method for optically active food flavor chemicals.
PubMed: The health effects of menthol cigarettes as compared to non-menthol cigarettes.
PubMed: Menthol cigarettes and smoking cessation behavior.
PubMed: Menthol cigarette smoking and nicotine dependence.
PubMed: Menthol and initiation of cigarette smoking.
PubMed: Sensory properties of menthol and smoking topography.
PubMed: Marketing of menthol cigarettes and consumer perceptions.
PubMed: US attitudes about banning menthol in cigarettes: results from a nationally representative survey.
PubMed: The threat of menthol cigarettes to U.S. public health.
PubMed: A lost opportunity for public health--the FDA advisory committee report on menthol.
PubMed: Menthol sensory qualities and smoking topography: a review of tobacco industry documents.
PubMed: Menthol cigarettes and smoking initiation: a tobacco industry perspective.
PubMed: FDA finding may curb mentholated cigarette availability.
PubMed: Lung cancer risk among smokers of menthol cigarettes.
PubMed: Comparison of serum cotinine concentration within and across smokers of menthol and nonmenthol cigarette brands among non-Hispanic black and non-Hispanic white U.S. adult smokers, 2001-2006.
PubMed: Toxicity of Schizonpeta multifida essential oil and its constituent compounds towards two grain storage insects.
PubMed: Tobacco firms move to stop FDA banning menthol cigarettes.
PubMed: Sensory stimulation to improve swallowing reflex and prevent aspiration pneumonia in elderly dysphagic people.
PubMed: Menthol cigarettes: moving toward a broader definition of harm.
PubMed: Hemisynthesis of dihydroumbellulols from umbellulone: new cooling compounds.
PubMed: Oral epithelial cells are activated via TRP channels.
PubMed: Menthol and non-menthol smoking: the impact of prices and smoke-free air laws.
PubMed: Composition and antimicrobial activities of Lippia multiflora Moldenke, Mentha x piperita L. and Ocimum basilicum L. essential oils and their major monoterpene alcohols alone and in combination.
PubMed: Yield, content, and composition of peppermint and spearmints as a function of harvesting time and drying.
PubMed: TRPM8 mediates cold and menthol allergies associated with mast cell activation.
PubMed: Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four Mentha species.
PubMed: Relation between developmental stage, sensory properties, and volatile content of organically and conventionally grown pac choi (Brassica rapa var. Mei Qing Choi).
PubMed: Ultraviolet-B and photosynthetically active radiation interactively affect yield and pattern of monoterpenes in leaves of peppermint (Mentha x piperita L.).
PubMed: Efficacy and safety profile of a topical methyl salicylate and menthol patch in adult patients with mild to moderate muscle strain: a randomized, double-blind, parallel-group, placebo-controlled, multicenter study.
PubMed: Menthol and non-menthol cigarette use among Black smokers in Southern California.
PubMed: A review and assessment of menthol employed as a cigarette flavoring ingredient.
PubMed: Evaluation of certain food additives.
PubMed: Levels of mint and wintergreen flavorants: smokeless tobacco products vs. confectionery products.
PubMed: Probable warfarin interaction with menthol cough drops.
PubMed: FDA exercises new authority to regulate tobacco products, but some limits remain.
PubMed: The effects of swilling an L(-)-menthol solution during exercise in the heat.
PubMed: Influence of composition (CO2 and sugar) on aroma release and perception of mint-flavored carbonated beverages.
PubMed: Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice.
PubMed: Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1.
PubMed: Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities.
PubMed: Repellency of an over-the-counter essential oil product in China against workers of red imported fire ants.
PubMed: Antioxidant property of volatile oils determined by the ferric reducing ability.
PubMed: Fragrance material review on l-menthol.
PubMed: Fragrance material review on 4-carvomenthenol.
PubMed: Fragrance material review on d-menthol.
PubMed: Fragrance material review on d,l-menthol.
PubMed: Fragrance material review on menthol racemic.
PubMed: Fragrance material review on menthol.
PubMed: Fragrance material review on geranodyle.
PubMed: The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity.
PubMed: Differential transfer of dietary flavour compounds into human breast milk.
PubMed: Oral lichenoid lesions and allergy to dental materials.
PubMed: pH memory of immobilized lipase for (+/-)-menthol resolution in ionic liquid.
PubMed: Isolation and characterization of Escherichia coli mutants exhibiting altered response to thymol.
PubMed: Screening of antibacterial activities of twenty-one oxygenated monoterpenes.
PubMed: Modulation of oral heat and cold pain by irritant chemicals.
PubMed: Enhancing antioxidant, antiproliferation, and free radical scavenging activities in strawberries with essential oils.
PubMed: The effects of foods, beverages, and other factors on cigarette palatability.
PubMed: Dandruff, seborrheic dermatitis, and psoriasis drug products containing coal tar and menthol for over-the-counter human use; amendment to the monograph. Final rule.
PubMed: Assessment of sensitization potential of monoterpenes using the rat popliteal lymph node assay.
PubMed: Rhinitis because of toothpaste and other menthol-containing products.
PubMed: Comparison of three lychee cultivar odor profiles using gas chromatography-olfactometry and gas chromatography-sulfur detection.
PubMed: TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
PubMed: Possible effects on smokers of cigarette mentholation: a review of the evidence relating to key research questions.
PubMed: Use of Rhodotorula minuta live cells hosted in water-in-oil macroemulsion for biotrasformation reaction.
PubMed: Volatile monoterpenes in black currant (Ribes nigrum L.) juice: effects of heating and enzymatic treatment by beta-glucosidase.
PubMed: Evaluation of residues of essential oil components in honey after different anti-varroa treatments.
PubMed: Alpha-anomer-selective glucosylation of menthol with high yield through a crystal accumulation reaction using lyophilized cells of Xanthomonas campestris WU-9701.
PubMed: Effects of antimicrobial components of essential oils on growth of Bacillus cereus INRA L2104 in and the sensory qualities of carrot broth.
PubMed: Improvement of table grapes quality and safety by the combination of modified atmosphere packaging (MAP) and eugenol, menthol, or thymol.
PubMed: Effect of harvest time and drying method on biomass production, essential oil yield, and quality of peppermint (Mentha x piperita L.).
PubMed: The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes.
PubMed: Biofilm in water pipelines; a potential source for off-flavours in the drinking water.
PubMed: Flavor release and perception in hard candy: influence of flavor compound-compound interactions.
PubMed: In vivo studies on the metabolism of the monoterpene pulegone in humans using the metabolism of ingestion-correlated amounts (MICA) approach: explanation for the toxicity differences between (S)-(-)- and (R)-(+)-pulegone.
PubMed: Antifungal activity of peppermint and sweet basil essential oils and their major aroma constituents on some plant pathogenic fungi from the vapor phase.
PubMed: In vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens.
PubMed: Common herbs, essential oils, and monoterpenes potently modulate bone metabolism.
PubMed: Lytic activity of l-menthol derivatives against the snow blight disease fungus, Micronectriella nivalis.
PubMed: Simulated microgravity [bed rest] has little influence on taste, odor or trigeminal sensitivity.
PubMed: Enzymatic synthesis of aroma compound xylosides using transfer reaction by Trichoderma longibrachiatum xylanase.
PubMed: Characterization of essential oils from lamiaceae species by fourier transform Raman spectroscopy.
PubMed: Phytochemical induction by herbivores could affect quality of essential oils from aromatic plants.
PubMed: Antimicrobial screening of Mentha piperita essential oils.
PubMed: The phenolic hydroxyl group of carvacrol is essential for action against the food-borne pathogen Bacillus cereus.
PubMed: Essential oil composition of sachalinmint from Norway detected by solid-phase microextraction and gas chromatography-mass spectrometry analysis.
PubMed: Factors affecting the resolution of dl-menthol by immobilized lipase-catalyzed esterification in organic solvent.
PubMed: Systematic studies on structure and physiological activity of cyclic alpha-keto enamines, a novel class of "cooling" compounds.
PubMed: Fullerene modified supported lipid membrane as sensitive element of sensor for odorants.
PubMed: Efficacy of essential oils of Caesulia axillaris and Mentha arvensis against some storage pests causing biodeterioration of food commodities.
PubMed: 1,8-cineol, a food flavoring agent, prevents ethanol-induced gastric injury in rats.
PubMed: Genetic and biochemical characterization of a novel monoterpene epsilon-lactone hydrolase from Rhodococcus erythropolis DCL14.
PubMed: Floral Origin Markers of Chestnut and Lime Tree Honeys.
PubMed: Xanthobacter sp. C20 contains a novel bioconversion pathway for limonene.
PubMed: Suppression of the furylfuramide-induced SOS response by monoterpenoids with a p-menthane skeleton using the Salmonella typhimurium TA1535/pSK1002 Umu test.
PubMed: Cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; amendment of final monograph for OTC antitussive drug products. Food and Drug Administration, HHS. Final rule.
PubMed: Evaluation of certain food additives. Fifty-first report of the Joint FAO/WHO Expert Committee on Food Additives.
PubMed: Purification and characterization of a Baeyer-Villiger mono-oxygenase from Rhodococcus erythropolis DCL14 involved in three different monocyclic monoterpene degradation pathways.
PubMed: Biotransformation of (+)- and (-)-menthol by the larvae of common cutworm (Spodoptera litura).
PubMed: Monoterpene composition of essential oil from peppermint (Mentha x piperita L.) with regard to leaf position using solid-phase microextraction and gas chromatography/mass spectrometry analysis.
PubMed: Biogenetic studies in Mentha x piperita. 2. Stereoselectivity in the bioconversion of pulegone into menthone and isomenthone.
PubMed: Effect of sucrose on the perceived flavor intensity of chewing gum.
PubMed: Biosynthesis of menthofuran in Mentha x piperita: stereoselective and mechanistic studies.
PubMed: Enantiomeric purity and odor characteristics of 2- and 3-acetoxy-1, 8-cineoles in the rhizomes of Alpinia galanga willd.
PubMed: Disposition kinetics and effects of menthol.
PubMed: The generalizability of capsaicin sensitization and desensitization.
PubMed: Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.
PubMed: Mutagenicity testing (+/-)-camphor, 1,8-cineole, citral, citronellal, (-)-menthol and terpineol with the Salmonella/microsome assay.
PubMed: Lack of histological cerebellar changes in Wistar rats given pulegone for 28 days. Comparison of immersion and perfusion tissue fixation.
PubMed: 13-week inhalation toxicity study of menthol cigarette smoke.
PubMed: Estimation of menthol in Pan Masala samples by a spectrophotometric method.
PubMed: Validation of the assay method for camphor and menthol in a herbal drug preparation.
PubMed: Gas chromatographic-mass spectrometric method to characterise the transfer of dietary odorous compounds into plasma and milk.
PubMed: Sensitization and desensitization to capsaicin and menthol in the oral cavity: interactions and individual differences.
PubMed: Contact sensitivity to food additives can cause oral and perioral symptoms.
PubMed: Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.
PubMed: Variation in odor thresholds for l-carvone and cineole and correlations with suprathreshold intensity ratings.
PubMed: Prevalence of food allergy and intolerance in the adult Dutch population.
PubMed: Determination of menthol in honey by gas chromatography.
PubMed: Antibacterial activity of essential oil components.
PubMed: Halothane and eucalyptol as alternatives to chloroform for softening gutta-percha.
PubMed: Effects of drug metabolism modifiers on pulegone-induced hepatotoxicity in mice.
PubMed: Capsaicin and its effects on olfaction and trigeminal chemoreception.
PubMed: Chewing-gum preservative induced toxidermic vasculitis.
PubMed: Preparative resolution of D,L-threonine catalyzed by immobilized phosphatase.
PubMed: Effect of a proprietary rubefacient "Tiger Balm" on rabbit skin.
PubMed: Monographs on fragrance raw materials.
PubMed: [Psychotropic action of some aromatic substances used in food].
PubMed: Palindromic rheumatism: a request.
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