methyl pyruvate, 600-22-6

Articles:

PubMed:	l-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2.
PubMed:	Extended reaction scope of thiamine diphosphate dependent cyclohexane-1,2-dione hydrolase: from C-C bond cleavage to C-C bond ligation.
PubMed:	Acuticoccus yangtzensis gen. nov., sp. nov., a novel member in the family Rhodobacteraceae, isolated from the surface water of the Yangtze Estuary.
PubMed:	Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis.
PubMed:	T-type Ca2+ channel blocker, KYS05090 induces autophagy and apoptosis in A549 cells through inhibiting glucose uptake.
PubMed:	Oxidative damage to mitochondria at the nodes of Ranvier precedes axon degeneration in ex vivo transected axons.
PubMed:	Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells.
PubMed:	Kinetic characterization of recombinant Bacillus coagulans FDP-activated l-lactate dehydrogenase expressed in Escherichia coli and its substrate specificity.
PubMed:	Products and mechanism of the reactions of OH radicals and Cl atoms with methyl methacrylate (CH2═C(CH3)C(O)OCH3) in the presence of NOx.
PubMed:	3-Methyl pyruvate enhances radiosensitivity through increasing mitochondria-derived reactive oxygen species in tumor cell lines.
PubMed:	Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.
PubMed:	Stereospecific synthesis of a twinned alanine ester.
PubMed:	Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.
PubMed:	Detection and characterization of impurities in commercial products with Fourier transform microwave spectroscopy.
PubMed:	Synthesis of cytochrome C oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death.
PubMed:	Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models.
PubMed:	Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes.
PubMed:	Atmospheric chemistry of two biodiesel model compounds: methyl propionate and ethyl acetate.
PubMed:	Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.
PubMed:	Troglitazone regulates anaplerosis via a pull/push affect on glutamate dehydrogenase mediated glutamate deamination in kidney-derived epithelial cells; implications for the Warburg effect.
PubMed:	A general approach to anionic acid-labile surfactants with tunable properties.
PubMed:	Glycolytic flux occurs in Drosophila melanogaster recovering from camptothecin treatment.
PubMed:	Kinetics and products of gas-phase reactions of ozone with methyl methacrylate, methyl acrylate, and ethyl acrylate.
PubMed:	AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets.
PubMed:	Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells.
PubMed:	Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.
PubMed:	Starvation in the midst of plenty: making sense of ceramide-induced autophagy by analysing nutrient transporter expression.
PubMed:	Ceramide starves cells to death by downregulating nutrient transporter proteins.
PubMed:	C1-symmetric oxazolinyl sulfoximines as ligands in copper-catalyzed asymmetric mukaiyama aldol reactions.
PubMed:	Keto-enol driven assembly of methyl pyruvate on Pt(111).
PubMed:	Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells.
PubMed:	Rhythm of the beta-cell oscillator is not governed by a single regulator: multiple systems contribute to oscillatory behavior.
PubMed:	(E)-Methyl 2-[(4-nitro-phen-yl)-hydrazono]-propanoate.
PubMed:	Evidence for C-H...O=C bonding in coadsorbed aromatic-carbonyl systems on Pt(111).
PubMed:	Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection.
PubMed:	Substrate effects on oscillations in metabolism, calcium and secretion in single mouse islets of Langerhans.
PubMed:	The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.
PubMed:	Regioselectively nucleus and/or side-chain fluorinated 2-(Phenanthryl)propionic acids by an effective combination of radical and organometallic chemistry.
PubMed:	P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism.
PubMed:	Overexpression of short heterodimer partner recovers impaired glucose-stimulated insulin secretion of pancreatic beta-cells overexpressing UCP2.
PubMed:	Taurine increases glucose sensitivity of UCP2-overexpressing beta-cells by ameliorating mitochondrial metabolism.
PubMed:	Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response.
PubMed:	Stereoselective generation of vicinal stereogenic quaternary centers by photocycloaddition of 5-methoxy oxazoles to alpha-keto esters: synthesis of erythro beta-hydroxy dimethyl aspartates.
PubMed:	Adsorption states and modifier-substrate interactions on Pt(111) relevant to the enantioselective hydrogenation of alkyl pyruvates in the Orito reaction.
PubMed:	Utility of historical vehicle-control data in the interpretation of the local lymph node assay.
PubMed:	Monitoring carbonyl-amine reaction between pyruvic acid and alpha-amino alcohols by FTIR spectroscopy--a possible route to Amadori products.
PubMed:	Dacrymenone and VM 3298-2--new antibiotics with antibacterial and antifungal activity.
PubMed:	Observation of high enantioselectivity for the gas phase hydrogenation of methyl pyruvate using supported Pt catalysts pre-modified with cinchonidine.
PubMed:	Studies with GIP/Ins cells indicate secretion by gut K cells is KATP channel independent.
PubMed:	Aspects of enantioselective heterogeneous catalysis: structure and reactivity of (S)-(-)-1-(1-naphthyl)ethylamine on Pt[111].
PubMed:	Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate.
PubMed:	Novel insulin/GIP co-producing cell lines provide unexpected insights into Gut K-cell function in vivo.
PubMed:	Potentiation and prolongation of the insulinotropic action of glucagon-like peptide 1 by methyl pyruvate or dimethyl ester of L-glutamic acid in a type 2 diabetes animal model.
PubMed:	New methyl pyruvate thiosemicarbazones and their copper and zinc complexes: synthesis, characterization, X-ray structures and biological activity.
PubMed:	Selective C-C bond activation of methyl pyruvate on Ni(111) to yield surface methoxycarbonyl.
PubMed:	Potentiation by methyl pyruvate of GLP-1 insulinotropic action in normal rats.
PubMed:	Methyl pyruvate initiates membrane depolarization and insulin release by metabolic factors other than ATP.
PubMed:	Differential regulation of [Ca2+]i oscillations in mouse pancreatic islets by glucose, alpha-ketoisocaproic acid, glyceraldehyde and glycolytic intermediates.
PubMed:	Energetic requirement of carbachol-induced Ca2+ signaling in single mouse beta-cells.
PubMed:	Insulin secretion, inositol phosphate levels, and phospholipase C isozymes in rodent pancreatic islets.
PubMed:	Use of a soluble tetrazolium compound to assay metabolic activation of intact beta cells.
PubMed:	Epoxidation reactions of unsaturated fatty esters with potassium peroxomonosulfate.
PubMed:	Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.
PubMed:	Influence of pyruvic acid methyl ester on rat pancreatic islets. Effects on insulin secretion, phosphoinositide hydrolysis, and sensitization of the beta cell.
PubMed:	Insulinotropic action of methyl pyruvate: enzymatic and metabolic aspects.
PubMed:	Insulinotropic action of methyl pyruvate: secretory, cationic, and biosynthetic aspects.
PubMed:	Effects of the methyl esters of pyruvate, succinate and glutamate on the secretory response to meglitinide analogues in rat pancreatic islets.
PubMed:	Activation of stimulus-secretion coupling in pancreatic beta-cells by specific products of glucose metabolism. Evidence for privileged signaling by glycolysis.
PubMed:	In vitro and in vivo insulinotropic action of methyl pyruvate.
PubMed:	Synthesis of 5-aminopentyl 4,6-O-[(R)-1-carboxyethylidene]-beta-D-galactopyranoside and its use as a ligand for the affinity chromatography of human serum amyloid P . protein.
PubMed:	Structural studies of the capsular polysaccharide of Klebsiella type 33.
PubMed:	Polarographic determination of methyl methacrylate.