meso-erythritol
(2R,3S)-butane-1,2,3,4-tetrol
 
Notes:
a four-carbon sugar that is found in algae, fungi, and lichens. it is twice as sweet as sucrose and can be used as a coronary vasodilator.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      ERTJFP ERYTHRITOL FCC
       
  • BOC Sciences
    • BOC Sciences
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      149-32-6 meso-Erythritol
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      Product(s):
      MP-027581 ERYTHRITOL
       
  • Glentham Life Sciences
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Product(s):
      HLCFD-192 Erythritol
       
  • O'Laughlin Industries
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      05-05800 meso-ERYTHRITOL
       
  • TCI AMERICA
    • TCI AMERICA
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      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      E0021 meso-Erythritol >99.0%(HPLC)(T)
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
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      Product(s):
      7220 Erythritol
       
Synonyms   Articles   Notes   Search
CAS Number: 149-32-6Picture of molecule3D/inchi
Other(deleted CASRN): 10030-58-7
ECHA EINECS - REACH Pre-Reg: 205-737-3
FDA UNII: RA96B954X6
Nikkaji Web: J43.360H
Beilstein Number: 1719753
MDL: MFCD00004710
XlogP3: -2.30 (est)
Molecular Weight: 122.12050000
Formula: C4 H10 O4
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor enhancers, humectants, carriers, sweeteners
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 401 7 Erythritol View - notice PDF
GRN 382 Erythritol View - notice PDF
GRN 76 Erythritol View - notice PDF
GRN 208 Erythritol View - notice PDF
GRN 789 Erythritol View - notice PDF
JECFA Food Additive: Erythritol
FEMA Number: 4819 meso-erythritol
FDA:No longer provide for the use of these seven synthetic flavoring substances
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 119.00 to  123.00 °C. @ 760.00 mm Hg
Boiling Point: 330.00 to  331.00 °C. @ 760.00 mm Hg
Flash Point: 408.00 °F. TCC ( 208.70 °C. ) (est)
logP (o/w): -2.996 (est)
Soluble in:
 water, 6.10E+05 mg/L @ 22 °C (exp)
 alcohol, slightly
Insoluble in:
 diethyl ether
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Organoleptic Properties:
Odor Description:
at 100.00 %. 
odorless
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
American International Chemical, LLC.
ERYTHRITOL FCC
Atlantic Chemicals
Erythritol
BOC Sciences
For experimental / research use only.
meso-Erythritol
Carbosynth
For experimental / research use only.
meso-Erythritol
Cargill, Inc.
Zerose® erythritol
Flavor: characteristic
Erythritol, a natural, zero calorie, high digestive tolerance polyol, provides bulk, texture, high cooling effect and preservative benefits of sucrose in sugar-free and calorie-reduced products. Erythritol is suitable for dental health, weight management and sugar avoiders.
Coompo
For experimental / research use only.
Erythritol from Plants ≥96%
ECSA Chemicals
ERYTHRITOL
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ExtraSynthese
For experimental / research use only.
meso-Erythritol
Foodchem International
Erythritol
Glentham Life Sciences
meso-Erythritol
Jiangyin Healthway
Erythritol
New functional food ingredients
Jungbunzlauer Suisse
ERYLITE®
Flavor: sweet
ERYLITE® is a novel bulk sweetener with a caloric value close to zero. Chemically, it is a four-carbon sugar alcohol (polyol). ERYLITE® is produced by microbial fermentation of a carbohydrate substrate. It is the only all-natural sugar alcohol available today.
Kraft Chemical
Erythritol
O'Laughlin Industries
Erythritol /Stevia agglomerated blend
10 to 1 sugar sweetness
O'Laughlin Industries
Erythritol /Stevia agglomerated blend
5 to 1 sugar sweetness
O'Laughlin Industries
Erythritol, FCC
O'Laughlin Industries
ERYTHRITOL/ STEVIA CO-CRYSTALLIZED BLEND
O'Laughlin Industries
ERYTHRITOL/ STEVIA CO-CRYSTALLIZED BLEND
Penta International
meso-ERYTHRITOL
Prinova
Erythritol FCC
Santa Cruz Biotechnology
For experimental / research use only.
meso-Erythritol ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
meso-Erythritol ≥99%
Sinofi Food Ingredients
Erythritol
Flavor: characteristic
Sugar Substitutes, Chewing Gum, Beverages, Confections, Baking Food, Chocolate, Instant Coffee, Ice Cream.
TCI AMERICA
For experimental / research use only.
meso-Erythritol >99.0%(HPLC)(T)
United International
Erythritol
Viachem
Erythritol
Odor: bland
Use: Erythritol, C4H10O4, is a novel bulk sweetener with a caloric value close to zero. Chemically, it is a four-carbon sugar alcohol (polyol). Erythritol, a white crystalline powder, is made through fermentation.
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  7000 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 98, 1936.

intravenous-dog LDLo  5000 mg/kg
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 576, 1989.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor enhancers, humectants, carriers, sweeteners
Recommendation for meso-erythritol usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 28. Update in publication number(s): 29
Click here to view publication 28
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 5000.0000012500.00000
beverages(alcoholic): 5000.0000012500.00000
breakfast cereal: 12500.0000017500.00000
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 12500.0000017500.00000
fruit ices: 5000.0000012500.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: 12500.0000017500.00000
instant coffee / tea: 5000.0000012500.00000
jams / jellies: --
meat products: --
milk products: 12500.0000017500.00000
nut products: 12500.0000017500.00000
other grains: 12500.0000017500.00000
poultry: --
processed fruits: 5000.0000012500.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Statement in relation to the safety of erythritol (E 968) in light of new data, including a new paediatric study on the gastrointestinal tolerability of erythritol
View page or View pdf
ment on a refined dietary exposure assessment of erythritol (E 968) taking into account additional data provided
View page or View pdf
Scientific Opinion on the safety of the proposed extension of use of erythritol (E 968) as a food additive
View page or View pdf
Sugar-free hard confectionery with at least 90% erythritol and reduction of dental plaque which reduces the risk of dental caries: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006
View page or View pdf
Outcome of the public consultation on a draft protocol for assessing exposure to sweeteners as part of their safety assessment under the food additives re-evaluation programme
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 149-32-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 222285
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 (2R,3S)-butane-1,2,3,4-tetrol
Chemidplus: 0000149326
RTECS: KF2000000 for cas# 149-32-6
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References:
 (2R,3S)-butane-1,2,3,4-tetrol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 149-32-6
Pubchem (cid): 222285
Pubchem (sid): 134975586
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): C00503
HMDB (The Human Metabolome Database): HMDB02994
Export Tariff Code: 2940.00.6000
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
FAO: ERYTHRITOL
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Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 algae
Search  PMC Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 antierythrite
(R*,S*)-1,2,3,4-butane tetrol
(2R,3S)-butane-1,2,3,4-tetraol
(2R,3S)-butane-1,2,3,4-tetrol
meso-butane-1,2,3,4-tetrol
(2R,3S)-1,2,3,4-butanetetrol
(R*,R*)-1,2,3,4-butanetetrol
DL-1,2,3,4-butanetetrol
1,2,3,4-butanetetrol, (2R,3S)-
(2R,3S)-1,2,3,4-butantetrol
 erythrite
(R*,S*)-tetrahydroxybutane
DL-threitol
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Amplification of Hofmeister Effect by Alcohols.
PubMed: Recognition of riboflavin and the capsular polysaccharide of Haemophilus influenzae type b by antibodies generated to the haptenic epitope D-ribitol.
PubMed: Gluconobacter cerevisiae sp. nov., isolated from the brewery environment.
PubMed: Flow of suspensions of carbon nanotubes carrying phase change materials through microchannels and heat transfer enhancement.
PubMed: Chemical constituents from Glyphaea brevis and Monodora myristica: chemotaxonomic significance.
PubMed: [Simultaneous determination of meso-erythritol and L-erythrulose in fermentation broth using high performance liquid chromatography].
PubMed: Enzymatic synthesis of novel branched sugar alcohols mediated by the transglycosylation reaction of pullulan-hydrolyzing amylase II (TVA II) cloned from Thermoactinomyces vulgaris R-47.
PubMed: Characterization and inactivation of the membrane-bound polyol dehydrogenase in Gluconobacter oxydans DSM 7145 reveals a role in meso-erythritol oxidation.
PubMed: Reactivity of poly-alcohols towards OH, NO3 and SO4- in aqueous solution.
PubMed: Nonviral vectors with a biosurfactant MEL-A promote gene transfection into solid tumors in the mouse abdominal cavity.
PubMed: Gluconobacter sphaericus (Ameyama 1975) comb. nov., a brown pigment-producing acetic acid bacterium in the Alphaproteobacteria.
PubMed: Analysis of erythritol in foods by polyclonal antibody-based indirect competitive ELISA.
PubMed: Production of different types of mannosylerythritol lipids as biosurfactants by the newly isolated yeast strains belonging to the genus Pseudozyma.
PubMed: Characterization of the genus Pseudozyma by the formation of glycolipid biosurfactants, mannosylerythritol lipids.
PubMed: Interstrand and intrastrand DNA-DNA cross-linking by 1,2,3,4-diepoxybutane: role of stereochemistry.
PubMed: Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism.
PubMed: Pseudonocardia antarctica sp. nov. an Actinomycetes from McMurdo Dry Valleys, Antarctica.
PubMed: Determination of glycerol by gas chromatography using meso-erythritol as internal standard.
PubMed: Biosurfactant MEL-A dramatically increases gene transfection via membrane fusion.
PubMed: Herbaspirillum lusitanum sp. nov., a novel nitrogen-fixing bacterium associated with root nodules of Phaseolus vulgaris.
PubMed: Use of DSC to detect the heterogeneity of hydrothermal stability in the polyphenol-treated collagen matrix.
PubMed: New quinoproteins in oxidative fermentation.
PubMed: New developments in oxidative fermentation.
PubMed: Pseudomonas grimontii sp. nov.
PubMed: Modeling and measurements of solid-liquid and vapor-liquid equilibria of polyols and carbohydrates in aqueous solution.
PubMed: L-erythrulose production by oxidative fermentation is catalyzed by PQQ-containing membrane-bound dehydrogenase.
PubMed: Isolation of yeast Kurtzmanomyces sp. I-11, novel producer of mannosylerythritol lipid.
PubMed: Membrane-bound quinoprotein D-arabitol dehydrogenase of Gluconobacter suboxydans IFO 3257: a versatile enzyme for the oxidative fermentation of various ketoses.
PubMed: Phenotypic characterization of Microsporum canis isolated from cats and dogs.
PubMed: Herbaspirillum frisingense sp. nov., a new nitrogen-fixing bacterial species that occurs in C4-fibre plants.
PubMed: Determination of sugar alcohols in confectioneries by high-performance liquid chromatography after nitrobenzoylation.
PubMed: Characterization of a biosurfactant, mannosylerythritol lipid produced from Candida sp. SY16.
PubMed: Pseudomonas gessardii sp. nov. and Pseudomonas migulae sp. nov., two new species isolated from natural mineral waters.
PubMed: At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel.
PubMed: Liquid chromatographic determination of sugar alcohols in beverages and foods after nitrobenzoylation.
PubMed: Emended description of Herbaspirillum; inclusion of [Pseudomonas] rubrisubalbicans, a milk plant pathogen, as Herbaspirillum rubrisubalbicans comb. nov.; and classification of a group of clinical isolates (EF group 1) as Herbaspirillum species 3.
PubMed: Nutritional physiology and taxonomy of human-pathogenic Cladosporium-Xylohypha species.
PubMed: Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels.
PubMed: Nutritional physiology and selective isolation of Exophiala dermatitidis.
PubMed: Possibility of allergic reaction to dentin primer--application on the skin of guinea pigs.
PubMed: Bonding efficacy of erythritol methacrylate solutions as dentin primers.
PubMed: Volumetric properties of polyols (ethylene glycol, glycerol, meso-erythritol, xylitol and mannitol) in relation to their membrane permeability: group additivity and estimation of the maximum radius of their molecules.
PubMed: Usefulness of trehalose fermentation and L-glutamic acid decarboxylation for identification of biochemically aberrant Providencia stuartii strains.
PubMed: The use of meso-erythritol sensitivity discs in the typing of Brucella strains.
PubMed: [Determination of biovars of Brucella melitensis by manometric character: epidemiological value and relation to serovars].
PubMed: Osmotic deformation of red blood cell ghosts induced by carbohydrates.
PubMed: Effect of intracytoplasmic membrane development on oxidation of sorbitol and other polyols by Gluconobacter oxydans.
PubMed: Biotypes of Proteus rettgeri.
PubMed: Investigations with 1,4-bis-(2'-mesyloxyethylamino)-1,4-dideoxy-meso-erythritol (R-74).
PubMed: IDENTIFICATION OF ALTRO-HEPTULOSE AND L-THREITOL AS PRODUCTS OF MESO-ERYTHRITOL OXIDATION BY ACETOBACTER SUBOXYDANS.
PubMed: A note on meso-erythritol, a metabolic product of Aspergillus terreus.
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