Articles:
2-propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI)
Notes:
isolated from cynomorium songaricum Widespread in plants, e.g. peel of black cherry (Prunus serotina), lentil seeds and from red clover (Trifolium pratense). Found by Bate-Smith in 48% of investigated dicotyledonous and 55% of monocotyledonous spp.
Coumaric acid is a hydroxycinnamic acid, an organic compound that is a hydroxy derivative of cinnamic acid. There are three isomers, o-coumaric acid, m-coumaric acid, and p-coumaric acid, that differ by the position of the hydroxy substitution of the phenyl group. p-Coumaric acid is the most abundant isomer of the three in nature. (Wikipedia)
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GK1602 4-Hydroxycinnamic acid
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 08-58600 TRANS-P-HYDROXYCINNAMIC ACID
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| CAS Number: | 501-98-4 |  3D/inchi
|
| FDA UNII: | IBS9D1EU3J | |
| Nikkaji Web: | J6.196D | |
| Beilstein Number: | 2207381 | |
| MDL: | MFCD00004399 | |
| XlogP3: | 1.50 (est) | |
| Molecular Weight: | 164.16036000 | |
| Formula: | C9 H8 O3 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 214.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 346.00 to 347.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 351.00 °F. TCC ( 177.30 °C. ) (est) |
| logP (o/w): | 1.460 |
| Soluble in: | |
| alcohol | |
| water, 1.83e+004 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor Description: at 100.00 %. | balsamic |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| p-Coumaric acid 98% |
| BOC Sciences |
| For experimental / research use only. |
| trans-4-Hydroxycinnamic acid 0.98
Odor: characteristic Use: trans-4-Hydroxycinnamic acid isolated from the herb of Trifolium pratense. It has anti-bacteria effect against some gram-positive and gram-negative bacteria.
antibacterial; antimicrobial; |
| Glentham Life Sciences |
| 4-Hydroxycinnamic acid |
| Penta International |
| TRANS-P-HYDROXYCINNAMIC ACID |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| p-Coumaric acid ≥99% |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| p-Coumaric acid ≥98.0% (HPLC) |
| TCI AMERICA |
| For experimental / research use only. |
| trans-p-Coumaric Acid >98.0%(GC)(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 2850 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gendai no Rinsho. Vol. 3, Pg. 675, 1969. intraperitoneal-mouse LD50 1160 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gendai no Rinsho. Vol. 3, Pg. 675, 1969. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for (E)-para-hydroxycinnamic acid usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for (E)-para-hydroxycinnamic acid flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 637542 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| (E)-3-(4-hydroxyphenyl)prop-2-enoic acid | |
| Chemidplus: | 0000501984 |
| RTECS: | GD9095000 for cas# 501-98-4 |
References:
| (E)-3-(4-hydroxyphenyl)prop-2-enoic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 637542 |
| Pubchem (sid): | 134978583 |
| Flavornet: | 501-98-4 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C00811 |
| HMDB (The Human Metabolome Database): | HMDB02035 |
| FooDB: | FDB002594 |
| YMDB (Yeast Metabolome Database): | YMDB00498 |
| Export Tariff Code: | 2918.29.2000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| alfalfa Search Trop Picture | |
| apple plant Search Trop Picture | |
| artichoke jerusalem artichoke Search Trop Picture | |
| cherry black cherry Search Trop Picture | |
| clover red clover Search Trop Picture | |
| coffee Search PMC Picture | |
| coriander fruit Search Trop Picture | |
| coriander plant Search Trop Picture | |
| coriander seed Search Trop Picture | |
| cynomorium songaricum Search Trop Picture | |
| orange fruit juice Search Trop Picture | |
| pea Search Trop Picture | |
| sage Search Trop Picture | |
| wasabi Search Trop Picture |
Synonyms:
| cinnamic acid, p-hydroxy-, (E)- | |
| (E)-p- | coumaric acid |
| (E)-para- | coumaric acid |
| trans-4- | coumaric acid |
| trans-p- | coumaric acid |
| trans-para- | coumaric acid |
| (E)-p- | coumarinic acid |
| (E)-para- | coumarinic acid |
| trans-p- | coumarinic acid |
| trans-para- | coumarinic acid |
| (E)-3-(4- | hydroxy-phenyl)-acrylic acid |
| (E)-4- | hydroxycinnamic acid |
| (E)-p- | hydroxycinnamic acid |
| trans-4- | hydroxycinnamic acid |
| trans-p- | hydroxycinnamic acid |
| trans-para- | hydroxycinnamic acid |
| 4- | hydroxycinnamic acid (predominantly trans) |
| (E)-3-(4- | hydroxyphenyl)-2-propenoic acid |
| (2E)-3-(4- | hydroxyphenyl)acrylic acid |
| (2E)-3-(4- | hydroxyphenyl)acrylsäure |
| (2E)-3-(4- | hydroxyphenyl)prop-2-enoic acid |
| (E)-3-(4- | hydroxyphenyl)prop-2-enoic acid |
| (E)- | naringeninic acid |
| 2- | propenoic acid, 3-(4-hydroxyphenyl)-, (2E)- |
| 2- | propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI) |