Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Soluble in: |
| water, 3.668e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for 2-amino-4-picoline usage levels up to: | | not for fragrance use.
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Recommendation for 2-amino-4-picoline flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | amino-4-methylpyridine | alpha- | amino-gamma-picoline | | ascensil | 4- | methyl pyridine amine | 4- | methyl-2-aminopyridine | 4- | methyl-2-pyridinamine | 4- | methyl-2-pyridyl amine | | methyl-4-amino-2-pyridine | 4- | methylpyridin-2-amine | 4- | picolyl amine |
Articles:
PubMed: | New carboxamide derivatives bearing benzenesulphonamide as a selective COX-II inhibitor: Design, synthesis and structure-activity relationship. |
PubMed: | Sonochemical synthesis, characterization, and effects of temperature, power ultrasound and reaction time on the morphological properties of two new nanostructured mercury(II) coordination supramolecule compounds. |
PubMed: | Influences of temperature, power ultrasound and reaction time on the morphological properties of two new mercury(II) coordination supramolecular compounds. |
PubMed: | Tautomerization, molecular structure, transition state structure, and vibrational spectra of 2-aminopyridines: a combined computational and experimental study. |
PubMed: | Spectrophotometric study on the proton transfer reaction between 2-amino-4-methylpyridine with 2,6-dichloro-4-nitrophenol in methanol, acetonitrile and the binary mixture 50% methanol+50% acetonitrile. |
PubMed: | Room-temperature transition-metal-free one-pot synthesis of 3-aryl imidazo[1,2-a]pyridines via iodo-hemiaminal intermediate. |
PubMed: | Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway. |
PubMed: | An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors. |
PubMed: | Synthesis, structural characterization and dielectric properties of (C6H9N2)2(Hg0.75Cd0.25)Cl4 compound. |
PubMed: | ¹H-MAS-NMR chemical shifts in hydrogen-bonded complexes of chlorophenols (pentachlorophenol, 2,4,6-trichlorophenol, 2,6-dichlorophenol, 3,5-dichlorophenol, and p-chlorophenol) and amine, and H/D isotope effects on ¹H-MAS-NMR spectra. |
PubMed: | An amino-imino resonance study of 2-amino-4-methylpyridinium nitrate and 2-amino-5-methylpyridinium nitrate. |
PubMed: | Molecular and crystal structures, vibrational studies and quantum chemical calculations of 3 and 5-nitroderivatives of 2-amino-4-methylpyridine. |
PubMed: | Feasibility and dosimetry studies for 18F-NOS as a potential PET radiopharmaceutical for inducible nitric oxide synthase in humans. |
PubMed: | Growth and characterization of 2-amino-4-picolinium toluene sulfonate single crystal. |
PubMed: | Quantitative morphometry of respiratory tract epithelial cells as a tool for testing chemopreventive agent efficacy. |
PubMed: | DNA binding ability and hydrogen peroxide induced nuclease activity of a novel Cu(II) complex with malonate as the primary ligand and protonated 2-amino-4-picoline as the counterion. |
PubMed: | Supramolecular assembly of Mg(II) complexes directed by associative lone pair-pi/pi-pi/pi-anion-pi/pi-lone pair interactions. |
PubMed: | Robust recognition of malonate and 2-amino-4-picolinium in conjunction with M(II) as a triad (M = Ni/Co/Mn): role of this highly stable hydrogen-bonded motif in driving supramolecular self-assembly. |
PubMed: | Design and synthesis of 2-amino-4-methylpyridine analogues as inhibitors for inducible nitric oxide synthase and in vivo evaluation of [18F]6-(2-fluoropropyl)-4-methyl-pyridin-2-amine as a potential PET tracer for inducible nitric oxide synthase. |
PubMed: | Rhodium(I)-catalyzed one-pot synthesis of dialkyl ketones from methanol and alkenes through directed sp3 C-H bond activation of N-methylamine. |
PubMed: | Decreased beta-adrenoceptor chronotropic response in selenium-deficient mice: negative crosstalk between iNOS activity and cAMP accumulation. |
PubMed: | Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity. |
PubMed: | The fixation of bis(2-pyridylimino)isoindolato (BPI) ligands to dendritic carbosilanes. |
PubMed: | Inhibition of nitric oxide synthase aggravates cisplatin-induced nephrotoxicity: effect of 2-amino-4-methylpyridine. |
PubMed: | Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system. |
PubMed: | Synthesis of aliphatic ketones from allylic alcohols through consecutive isomerization and chelation-assisted hydroacylation by a rhodium catalyst. |
PubMed: | The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes. |
PubMed: | Effects of intravenous nitric oxide inhibitors on endotoxin-induced fever in prepubertal pigs. |
PubMed: | Effects of 4-methyl-2-aminopyridine on [3H]-noradrenaline overflow and contractility of isolated rabbit arteries. |
PubMed: | Analgesic activity of 2-amino-4-methylpyridine, a novel NO synthase inhibitor. |
PubMed: | 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. |
PubMed: | [Study of the effect of analgeton on the release of beta-endorphin and its effect on chronic hyperalgesia]. |
PubMed: | [Baroreflex effects on systolic arterial pressure and the intersystolic period in a comparative study of aminton and phenylephrine]. |
PubMed: | Cholinergic effect of 4-aminopyridine and adrenergic effect of 4-methyl-2-aminopyridine in cardiac muscle. |
PubMed: | Actions of 4-methyl-2-aminopyridine on neuromuscular transmission and contractility of skeletal muscle. |
PubMed: | [Effect of aminton on noradrenaline and adrenaline depots in the rat heart]. |
PubMed: | On the mechanism of action of 2-amino-4-methylpyridine, a morphine-like analgesic. |
PubMed: | [Effects of 4-methyl-2-aminopyridine on the heart and on circulation. Experimental research]. |
PubMed: | [Clinical trials with 4-methyl-2-aminopyridine camphorsulfonate in the shock from recent infarct]. |
PubMed: | [The action of 4-methyl-2-aminopyridine on the pressure of the greater and lesser circulations, on cerebral flow and on the coronary circulation]. |
PubMed: | [Toxicological and pharmacological characteristics of a new cardiocirculatory analeptic with prolonged action: 4-methyl-2-aminopyridine camphorsulfonate]. |
PubMed: | [Cardiocirculatory action of 4-methyl-2-aminopyridine camphorsulfonate]. |
PubMed: | Cardiac effects of 4-methyl-2-aminopyridine and some of its isomers. |
PubMed: | [Circulatory effects of 2-amino-4-picoline]. |
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