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1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-yl acetate
Notes:
None found
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Chemical sources Association Inc Exchange of knowledge Need This Item for Flavor? You can contact the Chemical Sources Association. Events Links Product(s):
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| CAS Number: | 72257-53-5 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 276-542-9 | |
| Nikkaji Web: | J299.074A | |
| XlogP3-AA: | 1.80 (est) | |
| Molecular Weight: | 212.28900000 | |
| Formula: | C12 H20 O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | Register name to be changed to (1R, 4S, 6S)-2-Oxabicyclo[2.2.2]octan-6-ol, 1,3,3-trimethyl-, 6-acetate. Register name to be changed to (1R, 4S, 6S)-2-Oxabicyclo[2.2.2]octan-6-ol, 1,3,3-trimethyl-, 6-acetate (EFFA, 2007b). | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| DG SANTE Food Flavourings: | 03.008 2-acetoxy-1,8-cineole |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid to solid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 89.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 253.00 to 254.00 °C. @ 760.00 mm Hg (est) |
| Boiling Point: | 299.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.018000 mmHg @ 25.00 °C. (est) |
| Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. ) |
| logP (o/w): | 2.261 (est) |
| Soluble in: | |
| alcohol | |
| water, 227.4 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| Similar Items: note | |
| 4,7,7-trimethyl-8-oxabicyclo[2.2.2]octane | |
Organoleptic Properties:
| Odor Type: herbal | |
| minty clean fresh eucalyptus | |
| Odor Description: at 100.00 %. | minty clean fresh eucalyptus |
| Flavor Type: herbal | |
| eucalyptus | |
| Taste Description: | eucalyptus |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the CSA |
Safety Information:
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
|
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for 2-acetoxy-1,8-cineole usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.037 (μg/capita/day) | ||
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3500 (μg/person/day) | ||
| Threshold of Concern: | 540 (μg/person/day) | ||
| Structure Class: | II | ||
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). | |||
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. | |||
| average usage mg/kg | maximum usage mg/kg | ||
| Dairy products, excluding products of category 02.0 (01.0): | 3.00000 | 15.00000 | |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 2.00000 | 10.00000 | |
| Edible ices, including sherbet and sorbet (03.0): | 3.00000 | 15.00000 | |
| Processed fruit (04.1): | 2.00000 | 10.00000 | |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - | |
| Confectionery (05.0): | 10.00000 | 50.00000 | |
| Chewing gum (05.0): | - | - | |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 5.00000 | 25.00000 | |
| Bakery wares (07.0): | 10.00000 | 50.00000 | |
| Meat and meat products, including poultry and game (08.0): | 2.00000 | 10.00000 | |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 2.00000 | 10.00000 | |
| Eggs and egg products (10.0): | - | - | |
| Sweeteners, including honey (11.0): | - | - | |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 5.00000 | 25.00000 | |
| Foodstuffs intended for particular nutritional uses (13.0): | 15.00000 | 75.00000 | |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 3.00000 | 15.00000 | |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | - | - | |
| Ready-to-eat savouries (15.0): | - | - | |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 23 (FGE.23): Aliphatic, alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16 and 26 (Commission Regulation (EC) No 1565/2000 of 18 July 2000 View page or View pdf | |
| Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 23, Revision 1 (FGE.23Rev1): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 26 and 30[1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 23, Revision 2 (FGE.23Rev2): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 22, 26 and 30 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 23, Revision 3 (FGE.23Rev3): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 22, 26 and 30 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 23, Revision 4 (FGE.23Rev4): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 22, 26 and 30 View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 72257-53-5 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 175002 |
| National Institute of Allergy and Infectious Diseases: | Data |
| 1,3,3-trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate | |
| Chemidplus: | 0072257535 |
References:
| 1,3,3-trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 175002 |
| Pubchem (sid): | 135153937 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| berry mixed berry | FL | |
| blackberry | FL | |
| clean | ||
| cornmint | FL/FR | |
| croton eluteria bark | FL/FR | |
| cumin oil replacer | FR | |
| currant black currant | FL | |
| eucalyptus oil replacer | FR | |
| fruit | FR | |
| ginger root oil replacer | FR | |
| herbal | FL | |
| mint | FL | |
| pea green pea | FL | |
| pennyroyal | FL/FR | |
| peppermint | FL | |
| spearmint | FL | |
| tansy oil replacer | FL/FR |
Occurrence (nature, food, other): note
| bay laurel Search Trop Picture |
Synonyms:
| 2-oxa | bicyclo(2.2.2)octan-6-ol, 1,3,3-trimethyl-, acetate |
| (1R, 4S, 6S)-2-oxa | bicyclo[2.2.2]octan-6-ol, 1,3,3-trimethyl-, 6-acetate |
| 2-oxa | bicyclo[2.2.2]octan-6-ol, 1,3,3-trimethyl-, acetate |
| exo-2- | hydroxycineole acetate |
| 1,3,3- | trimethyl-2-oxabicyclo(2.2.2)octan-6-ol acetate |
| 1,3,3- | trimethyl-2-oxabicyclo(2.2.2)octan-6-yl acetate |
| 1,3,3- | trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate |
| 1,3,3- | trimethyl-2-oxabicyclo[2.2.2]octan-6-ol acetate |
| 1,3,3- | trimethyl-2-oxabicyclo[2.2.2]octan-6-yl acetate |
| alpha,alpha,6- | trimethyl-7-oxabicycloheptane-3-methanol acetate |
| (4,7,7- | trimethyl-8-oxabicyclo[2.2.2]octan-5-yl) acetate |