benfotiamine, 22457-89-2

Articles:

PubMed:	Pharmacokinetic study of benfotiamine and the bioavailability assessment compared to thiamine hydrochloride.
PubMed:	A novel spectral resolution and simultaneous determination of multicomponent mixture of Vitamins B1, B6, B12, Benfotiamine and Diclofenac in tablets and capsules by derivative and MCR-ALS.
PubMed:	The effect of benfotiamine on mu-opioid receptor mediated antinociception in experimental diabetes.
PubMed:	Benfotiamine upregulates antioxidative system in activated BV-2 microglia cells.
PubMed:	Effect of benfotiamine in podocyte damage induced by peritoneal dialysis fluid.
PubMed:	Paraptosis cell death induction by the thiamine analog benfotiamine in leukemia cells.
PubMed:	Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia.
PubMed:	A randomized, double-blind, crossover, placebo-controlled trial of 6 weeks benfotiamine treatment on postprandial vascular function and variables of autonomic nerve function in Type 2 diabetes.
PubMed:	Benfotiamine enhances antioxidant defenses and protects against cisplatin-induced DNA damage in nephrotoxic rats.
PubMed:	Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence.
PubMed:	Variability of skin autofluorescence measurement over 6 and 12 weeks and the influence of benfotiamine treatment.
PubMed:	Liver, plasma and erythrocyte levels of thiamine and its phosphate esters in rats with acute ethanol intoxication: a comparison of thiamine and benfotiamine administration.
PubMed:	Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose.
PubMed:	Change in psychiatric symptomatology after benfotiamine treatment in males is related to lifetime alcoholism severity.
PubMed:	Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages.
PubMed:	Annexin V imaging detects diabetes-accelerated apoptosis and monitors the efficacy of benfotiamine treatment in ischemic limbs of mice.
PubMed:	Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations.
PubMed:	Pharmacokinetics of the transdermal delivery of benfotiamine.
PubMed:	The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial.
PubMed:	Antiglycation activity of thiamin-HCl and benfotiamine in diabetic condition.
PubMed:	Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.
PubMed:	[The effect of long-chain polyunsaturated higher ω-3 fatty acids, benfotiamine and α-lipoic acid on the lipid metabolism in patients with diabetes mellitus type 2 and cardiovascular autonomic neuropathy].
PubMed:	Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis.
PubMed:	Benfotiamine counteracts smoking-induced vascular dysfunction in healthy smokers.
PubMed:	Solubility enhancement of benfotiamine, a lipid derivative of thiamine by solid dispersion technique.
PubMed:	Preventive effects of benfotiamine in chronic diabetic complications.
PubMed:	Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.
PubMed:	Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.
PubMed:	The multifaceted therapeutic potential of benfotiamine.
PubMed:	The defensive effect of benfotiamine in sodium arsenite-induced experimental vascular endothelial dysfunction.
PubMed:	A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy.
PubMed:	Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes.
PubMed:	PP2A contributes to endothelial death in high glucose: inhibition by benfotiamine.
PubMed:	Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages.
PubMed:	Comment on: Fraser et al. The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial. Diabetes Care 2012;35:1095-1097.
PubMed:	Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response.
PubMed:	Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1.
PubMed:	Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment.
PubMed:	Thiamine and benfotiamine prevent apoptosis induced by high glucose-conditioned extracellular matrix in human retinal pericytes.
PubMed:	Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1-mediated survival pathway.
PubMed:	Pharmacologic Approaches Against Advanced Glycation End Products (AGEs) in Diabetic Cardiovascular Disease.
PubMed:	Detection of transketolase in bone marrow-derived insulin-producing cells: benfotiamine enhances insulin synthesis and glucose metabolism.
PubMed:	Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.
PubMed:	Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro.
PubMed:	Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis.
PubMed:	Antinociceptive interaction between benfotiamine and resveratrol in capsaicin-induced licking.
PubMed:	Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat.
PubMed:	Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes.
PubMed:	Benfotiamine in the treatment of diabetic polyneuropathy--a three-week randomized, controlled pilot study (BEDIP study).
PubMed:	Effectiveness of different benfotiamine dosage regimens in the treatment of painful diabetic neuropathy.
PubMed:	Synergistic antiallodynic interaction between gabapentin or carbamazepine and either benfotiamine or cyanocobalamin in neuropathic rats.
PubMed:	Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study.
PubMed:	Thiamine and benfotiamine prevent increased apoptosis in endothelial cells and pericytes cultured in high glucose.
PubMed:	Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose.
PubMed:	Pharmacokinetics of thiamine derivatives especially of benfotiamine.
PubMed:	High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus.
PubMed:	Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.
PubMed:	Benfotiamine reduces genomic damage in peripheral lymphocytes of hemodialysis patients.
PubMed:	Benfotiamine relieves inflammatory and neuropathic pain in rats.
PubMed:	Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine.
PubMed:	Benfotiamine in treatment of alcoholic polyneuropathy: an 8-week randomized controlled study (BAP I Study).
PubMed:	Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.
PubMed:	Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha.
PubMed:	Comparative autoradiographic investigations on the tissue distribution of benfotiamine versus thiamine in mice.
PubMed:	Benfotiamine attenuates nicotine and uric acid-induced vascular endothelial dysfunction in the rat.
PubMed:	Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.
PubMed:	Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated albumin.
PubMed:	Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes.
PubMed:	Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications.
PubMed:	Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative.
PubMed:	Current therapeutic interventions in the glycation pathway: evidence from clinical studies.
PubMed:	Efficacy and tolerability of advanced glycation end-products inhibitor in osteoarthritis: a randomized, double-blind, placebo-controlled study.
PubMed:	Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.
PubMed:	Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling.
PubMed:	A benfotiamine-vitamin B combination in treatment of diabetic polyneuropathy.
PubMed:	New oral dosage form for elderly patients. II. Release behavior of benfotiamine from silk fibroin gel.
PubMed:	[The immunometaboic effects of benfotiamine and riboxine on hemolytic anemia].
PubMed:	Boosting the pentose phosphate pathway restores cardiac progenitor cell availability in diabetes.
PubMed:	[Oral benfotiamine therapy. Thus you protect the nerves of diabetic patients].
PubMed:	[Chronic alcohol abuse. Benfotiamine in alcohol damage is a must].
PubMed:	Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate.
PubMed:	Adiponectin decreases postprandially following a heat-processed meal in individuals with type 2 diabetes: an effect prevented by benfotiamine and cooking method.
PubMed:	Benfotiamine. Monograph.
PubMed:	Vitamins and their derivatives in the prevention and treatment of metabolic syndrome diseases (diabetes).
PubMed:	Advanced glycation end-products inhibition improves endothelial dysfunction in rheumatoid arthritis.
PubMed:	[The effect of benfothiamine in the therapy of diabetic polyneuropathy].
PubMed:	High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine.
PubMed:	Detrimental effects of acute hyperglycaemia on the rat heart.
PubMed:	[Pathomechanism of diabetic neuropathy: background of the pathogenesis-oriented therapy].
PubMed:	[Clinical use of benphothiamine].
PubMed:	[A comparative study of blood thiamine levels after injection of thiamine chlorhydrate and per os administration of Benfotiamine].
PubMed:	Burning through the pain: treatments for diabetic neuropathy.
PubMed:	Evidence for altered thiamine metabolism in diabetes: Is there a potential to oppose gluco- and lipotoxicity by rational supplementation?
PubMed:	Different apoptotic responses of human and bovine pericytes to fluctuating glucose levels and protective role of thiamine.
PubMed:	Effects of high glucose and thiamine on the balance between matrix metalloproteinases and their tissue inhibitors in vascular cells.
PubMed:	High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats.
PubMed:	Vitamin B and its derivatives for diabetic kidney disease.
PubMed:	Treatment of painful diabetic neuropathy.
PubMed:	Diabetic neuropathy and oxidative stress: therapeutic perspectives.
PubMed:	The detrimental effects of acute hyperglycemia on myocardial glucose uptake.
PubMed:	Thiamine deficiency induces anorexia by inhibiting hypothalamic AMPK.
PubMed:	Inhibition of AGEs formation by natural products.
PubMed:	Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.
PubMed:	High-throughput screening of small molecules identifies hepcidin antagonists.
PubMed:	Current options and perspectives in the treatment of diabetic neuropathy.
PubMed:	[The immunomodulating action of energizing preparations under physical loading].
PubMed:	A case of rheumatoid arthritis presenting with postherpetic neuralgia and abdominal-wall pseudohernia.
PubMed:	Glucose effects on the peritoneum: what can we learn from rodent models?
PubMed:	Lipid glycation and protein glycation in diabetes and atherosclerosis.
PubMed:	[Neuropathy pain: tactic of treatment].
PubMed:	[The role of neurotropic therapy in the treatment of acute sensorineural impairment of hearing following a viral infection].
PubMed:	[A relationship between analgesic and neurotropic effects by the example of milgamma].
PubMed:	[The optimization of the treatment of the vertebrogenic pain syndrome: neurotrophic treatment potentiates the effect of nonsteroidal anti-inflammatory drugs].
PubMed:	[The importance of the pharmaceutical form and the routes of administration of B-group vitamins for the efficacious treatment of neurosensorial hearing loss].
PubMed:	[Prophylactic and therapeutic application of thiamine (vitamin B1)--a new point of view].
PubMed:	[Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation].
PubMed:	Diabetic neuropathy: new strategies for treatment.
PubMed:	Vitamin B1 blocks damage caused by hyperglycemia.
PubMed:	Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control.
PubMed:	[Prevention of complications in diabetes mellitus. Interdisciplinary collaboration to control sequelae].
PubMed:	Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.
PubMed:	Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients?
PubMed:	Drugs for the treatment of diabetes complications. Zycose: a new player in the field?
PubMed:	[Cochleovestibular disorders: approaches to diagnostics and treatment].
PubMed:	[Sensorineural hearing loss: New prospects for therapy].
PubMed:	Oxidative stress in diabetic kidney disease.
PubMed:	Skin autofluorescence as a measure of advanced glycation endproduct deposition: a novel risk marker in chronic kidney disease.
PubMed:	[Diabetic neuropathies and angiopathies. Compensating for thiamine deficiency].
PubMed:	High-dose thiamine therapy counters dyslipidaemia in streptozotocin-induced diabetic rats.
PubMed:	[Pharmacologic therapy in peripheral diabetic polyneuropathy].
PubMed:	Diabetes mellitus induces bone marrow microangiopathy.
PubMed:	[The myocardial contractile function and central hemodynamics of patients with insulin-dependent diabetes mellitus during treatment].
PubMed:	[Treatment of neuropathies].
PubMed:	Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy.
PubMed:	Effectiveness and retention of thiamine and its analogs administered to steelhead and landlocked Atlantic salmon.
PubMed:	New approaches for the treatment of genomic damage in end-stage renal disease.
PubMed:	Vitamin B for treating peripheral neuropathy.
PubMed:	The potential role of thiamine (vitamin B1) in diabetic complications.
PubMed:	Inhibitors of advanced glycation end product formation and neurovascular dysfunction in experimental diabetes.
PubMed:	Schlafen 3, a novel gene, regulates colonic mucosal growth during aging.
PubMed:	[Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy].
PubMed:	[Correction of metabolic disturbances in patients with stable effort angina and metabolic syndrome].
PubMed:	[Structural and functional changes of arterial vessels in patients with ischemic heart disease and metabolic syndrome].
PubMed:	[Neurometabolic therapy of diabetic neuropathy].
PubMed:	[Development of therapeutic agents for diabetic neuropathies].
PubMed:	[Progress on the drug therapy for diabetic microangiopathies: AGE inhibitors].
PubMed:	[Diabetes mellitus. Retinal lesions should not exist!].
PubMed:	Bioavailability of water- and lipid-soluble thiamin compounds in broiler chickens.
PubMed:	Effect of high-dosed thiamine hydrochloride and S-benzoyl-thiamine-O-monophosphate on thiamine-status after chronic ethanol administration.
PubMed:	[Diabetic polyneuropathy treatment by milgamma-100 preparation].
PubMed:	A 6-month-old girl with cardiomyopathy who nearly died.
PubMed:	Therapeutic efficacy of "Milgamma" in patients with painful diabetic neuropathy.
PubMed:	[The effectiveness of the neurotropic agents: benfotiamin combinations].
PubMed:	[Physical work capacity in diabetes mellitus under treatment].
PubMed:	Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition.
PubMed:	The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.
PubMed:	Advances in biochemical mechanisms of diabetic retinopathy.
PubMed:	An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
PubMed:	Evaluating thiamine deficiency in patients with diabetes.
PubMed:	[Role of mitochondrial dysfunction in pathogenesis of diabetic microangiopathy].
PubMed:	[Milgamma in the treatment of chronic neurosensory hypoacusis].
PubMed:	[Treatment of neuropathies].
PubMed:	[Bendotiamine efficacy in alcoholic polyneuropathy therapy].
PubMed:	[Diabetic neuropathy].
PubMed:	Biokinetic parameters and metabolism of S-benzoylthiamine-O-monophosphate.
PubMed:	Alteration of thiamine pharmacokinetics by end-stage renal disease (ESRD).
PubMed:	Comparative bioavailability of various thiamine derivatives after oral administration.
PubMed:	Excretion of intracorporeal cadmium with S-benzoylthiamin monophosphate.
PubMed:	[Characteristic features of 35S-benzoylthiamine monophosphate in albino mice].
PubMed:	Peripheral neuropathy: pathogenic mechanisms and alternative therapies.
PubMed:	Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
PubMed:	Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats.