Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear liquid (est) |
Assay: | 98.00 to 100.00 % sum of isomers
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.81400 to 0.81600 @ 20.00 °C.
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Pounds per Gallon - (est).: | 6.781 to 6.798
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Refractive Index: | 1.41400 to 1.41600 @ 20.00 °C.
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Boiling Point: | 136.00 to 139.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 2.634000 mmHg @ 25.00 °C. (est) |
Flash Point: | 115.00 °F. TCC ( 46.11 °C. )
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logP (o/w): | 1.702 (est) |
Soluble in: |
| alcohol | | water, 1.171e+004 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: winey |
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| chemical winey fruity fatty terpenic cauliflower |
Odor Description: at 1.00 % in dipropylene glycol. | chemical winey fruity fatty terpenic cauliflower |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 10 - Flammable. R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 20/21 - When using do not eat, drink or smoke. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| butyl methyl carbinol | | hexan-2-ol | N- | hexan-2-ol | (±)-2- | hexanol | 2- | hexanol, (±)- | 2- | hydroxyhexane | | methylamyl alcohol | | methylpentanol | | pentanol, methyl- |
Articles:
PubMed: | Differential involvement of glutamate-gated chloride channel splice variants in the olfactory memory processes of the honeybee Apis mellifera. |
PubMed: | Redox self-sufficient whole cell biotransformation for amination of alcohols. |
PubMed: | Copper-organic frameworks assembled from in situ generated 5-(4-pyridyl)tetrazole building blocks: synthesis, structural features, topological analysis and catalytic oxidation of alcohols. |
PubMed: | Effect of compression on the relationship between viscosity and dielectric relaxation time in hydrogen-bonded primary alcohols. |
PubMed: | Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations. |
PubMed: | Volatile compounds emitted by Triatoma dimidiata, a vector of Chagas disease: chemical analysis and behavioural evaluation. |
PubMed: | Influence of cultivation parameters on the composition of volatile compounds and physico-chemical characteristics of kiwi fruit. |
PubMed: | Borenium ion catalyzed hydroboration of alkenes with N-heterocyclic carbene-boranes. |
PubMed: | Synergism between microwave irradiation and enzyme catalysis in transesterification of ethyl-3-phenylpropanoate with n-butanol. |
PubMed: | Enantioselective degradation of hexaconazole in rat hepatic microsomes in vitro. |
PubMed: | Effect of high hydrostatic pressure on the dielectric relaxation in a non-crystallizable monohydroxy alcohol in its supercooled liquid and glassy states. |
PubMed: | Selective hydroxylation of alkanes by an extracellular fungal peroxygenase. |
PubMed: | Exploring natural products for new taste sensations. |
PubMed: | Debye process and dielectric state of an alcohol in a nonpolar solvent. |
PubMed: | Synthesis of conformationally locked L-deoxythreosyl phosphonate nucleosides built on a bicyclo[3.1.0]hexane template. |
PubMed: | A greener enantioselective synthesis of the antiviral agent North-methanocarbathymidine (N-MCT) from 2-deoxy-d-ribose. |
PubMed: | Degradation of hexane and other recalcitrant hydrocarbons by a novel isolate, Rhodococcus sp. EH831. |
PubMed: | The effect of co-surfactant-modified micelles on chiral separations in EKC. |
PubMed: | Specific heat relaxation of an alcohol and implications for dielectric comparison. |
PubMed: | Volatile compounds in dry-cured Serrano ham subjected to high pressure processing. Effect of the packaging material. |
PubMed: | Effect of microemulsion component purity on the chromatographic figures of merit in chiral microemulsion electrokinetic chromatography. |
PubMed: | Synthesis, crystallization mechanism, and catalytic properties of titanium-rich TS-1 free of extraframework titanium species. |
PubMed: | Structure-dependent dc conductivity and relaxation time in the Debye-Stokes-Einstein equation. |
PubMed: | Influence of microemulsion chirality on chromatographic figures of merit in EKC: results with novel three-chiral-component microemulsions and comparison with one- and two-chiral-component microemulsions. |
PubMed: | Two-chiral component microemulsion EKC - chiral surfactant and chiral oil. Part 2: diethyl tartrate. |
PubMed: | Two-chiral-component microemulsion electrokinetic chromatography-chiral surfactant and chiral oil: part 1. dibutyl tartrate. |
PubMed: | Intramolecular cyclopropanation of unsaturated terminal epoxides and chlorohydrins. |
PubMed: | Purification and characterization of alcohol dehydrogenase reducing N-benzyl-3-pyrrolidinone from Geotrichum capitatum. |
PubMed: | Degradation of alkyl methyl ketones by Pseudomonas veronii MEK700. |
PubMed: | Relaxations and nano-phase-separation in ultraviscous heptanol-alkyl halide mixture. |
PubMed: | Chiral microemulsion electrokinetic chromatography: Effect of cosurfactant identity on enantioselectivity, methylene selectivity, resolution, and other chromatographic figures of merit. |
PubMed: | Uptake of organic gas phase species by 1-methylnaphthalene. |
PubMed: | Chirality in anesthesia II: stereoselective modulation of ion channel function by secondary alcohol enantiomers. |
PubMed: | Chirality in anesthesia I: minimum alveolar concentration of secondary alcohol enantiomers. |
PubMed: | Chiral microemulsion electrokinetic chromatography with two chiral components: Improved separations via synergies between a chiral surfactant and a chiral cosurfactant. |
PubMed: | Speed of sound measurements conducted at high pressures on aqueous alcohol and aqueous diol systems at T = 298.15 K. |
PubMed: | Stereoselective kinetic study of hexaconazole enantiomers in the rabbit. |
PubMed: | Dynamics of glass-forming liquids. VIII. Dielectric signature of probe rotation and bulk dynamics in branched alkanes. |
PubMed: | Separation of enantiomers in microemulsion electrokinetic chromatography using chiral alcohols as cosurfactants. |
PubMed: | Epoxide hydrolase: a mRNA induced by the fungal pathogen Alternaria alternata on rough lemon (Citrus jambhiri Lush). |
PubMed: | Direct observation of odd-even effect for chiral alkyl alcohols in solution using vibrational circular dichroism spectroscopy. |
PubMed: | Microemulsion electrokinetic chromatography for the analysis of green tea catechins: effect of the cosurfactant on the separation selectivity. |
PubMed: | On the mechanism of the unexpected facile formation of meso-diacetate products in enzymatic acetylation of alkanediols. |
PubMed: | Olfactory discrimination of structurally similar alcohols by cockroaches. |
PubMed: | Sorption behavior of triazole fungicides in Indian soils and its correlation with soil properties. |
PubMed: | Aroma active components in aqueous kiwi fruit essence and kiwi fruit puree by GC-MS and multidimensional GC/GC-O. |
PubMed: | Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. Characterization of an unusual acetal byproduct. |
PubMed: | Synthesis and Characterization of Basic Catalysts Based on Sodium-Magnesium Mixed Phosphates and Their Use in the Conversion of 2-Hexanol. |
PubMed: | Fragrance volatiles of developing and senescing carnation flowers. |
PubMed: | Headspace analysis of engine oil by gas chromatography/mass spectrometry. |
PubMed: | Persistence of hexaconazole, a triazole fungicide in soils. |
PubMed: | NAD(+)-dependent (S)-specific secondary alcohol dehydrogenase involved in stereoinversion of 3-pentyn-2-ol catalyzed by Nocardia fusca AKU 2123. |
PubMed: | Synthesis, Characterization, and Catalytic Uses of Mg(3)(PO(4))(2)/MgO Systems. |
PubMed: | Determination of free and glucuronated hexane metabolites without prior hydrolysis by liquid- and gas-chromatography coupled with mass spectrometry. |
PubMed: | Synthesis and Characterization of Magnesium Phosphates and Their Catalytic Properties in the Conversion of 2-Hexanol. |
PubMed: | Determination of n-hexane metabolites by liquid chromatography/mass spectrometry. 2. Glucuronide-conjugated metabolites in untreated urine samples by electrospray ionization. |
PubMed: | Odour coding is bilaterally symmetrical in the antennal lobes of honeybees (Apis mellifera). |
PubMed: | Metabolic interaction of n-hexane and methyl ethyl ketone in vitro in a head space rat liver S9 vial equilibration system. |
PubMed: | Comparison and in vivo relevance of two different in vitro head space metabolic systems: liver S9 and liver slices. |
PubMed: | Subcellular Localization of Secondary Lipid Metabolites Including Fragrance Volatiles in Carnation Petals. |
PubMed: | An investigation into the role of rat skeletal muscle as a site for xenobiotic metabolism using microsomes and isolated cells. |
PubMed: | Metabolism of n-hexane by rat liver and extrahepatic tissues and the effect of cytochrome P-450 inducers. |
PubMed: | Effects of n-hexane and its metabolites on cloned voltage-operated neuronal potassium channels. |
PubMed: | Method for the simultaneous quantification of n-hexane metabolites: application to n-hexane metabolism determination. |
PubMed: | Toxic effects of hexane derivatives on cultured rat Schwann cells. |
PubMed: | In vitro quantitative structure-activity relationship assessment of pyrrole adducts production by gamma-diketone-forming neurotoxic solvents. |
PubMed: | Tissue concentrations of methyl isobutyl ketone, methyl n-butyl ketone and their metabolites after oral or inhalation exposure. |
PubMed: | Pharmacodynamic and metabolic interactions between ethanol and two industrial solvents (methyl n-butyl ketone and methyl isobutyl ketone) and their principal metabolites in mice. |
PubMed: | Metabolic fate of methyl n-butyl ketone, methyl isobutyl ketone and their metabolites in mice. |
PubMed: | Isolation of acylcarnitines from urine: a comparison of methods and application to long-chain acyl-CoA dehydrogenase deficiency. |
PubMed: | Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. |
PubMed: | Changes in urinary n-hexane metabolites by co-exposure to various concentrations of methyl ethyl ketone and fixed n-hexane levels. |
PubMed: | The in vitro effects of alkanes, alcohols, and ketones on rat lung cytochrome P450-dependent alkoxyphenoxazone dealkylase activities. |
PubMed: | The relevance of 4,5-dihydroxy-2-hexanone in the excretion kinetics of n-hexane metabolites in rat and man. |
PubMed: | Resolution of enantiomeric amides on a cellulose tribenzoate chiral stationary phase. Mobile phase modifier effects on retention and stereo-selectivity. |
PubMed: | Anesthetic potencies of secondary alcohol enantiomers. |
PubMed: | Urinary excretion of 2,5-hexanedione and peripheral polyneuropathies workers exposed to hexane. |
PubMed: | Rat lung and liver microsomal cytochrome P-450 isozymes involved in the hydroxylation of n-hexane. |
PubMed: | Phthalate esters: effects of orally administered dibutylphthalate on cytochrome P-450 mediated metabolism in rat liver and lung. |
PubMed: | Metabolites and ketone body production following methyl n-butyl ketone exposure as possible indices of MnBK potentiation of carbon tetrachloride hepatotoxicity. |
PubMed: | Impairment of human polymorphonuclear leukocyte chemotaxis by 2,5-hexanedione. |
PubMed: | Respiratory-phase-related coding of olfactory information in the olfactory bulb of awake freely-breathing rabbits. |
PubMed: | Methodological investigations on the determination of n-hexane metabolites in urine. |
PubMed: | Analysis of n-hexane, 2-hexanone, 2,5-hexanedione, and related chemicals by capillary gas chromatography and high-performance liquid chromatography. |
PubMed: | Inhalation of isopropanol: induction of activating and deactivating enzymes in rat kidney and liver. Increased microsomal metabolism of n-hexane. |
PubMed: | Inhalation of butanols: changes in the cytochrome P-450 enzyme system. |
PubMed: | Selective inhibition by chloramphenicol of cytochrome P-450 isozymes in rat lung and liver involved in the hydroxylation of n-hexane. |
PubMed: | In vitro effect of n-hexane and its metabolites on selected enzymes in glycolysis, pentose phosphate pathway and citric acid cycle. |
PubMed: | Increased microsomal metabolism of n-hexane in rat kidney and liver after inhalation of isopropanol. |
PubMed: | Changes of n-hexane neurotoxicity and its urinary metabolites by long-term co-exposure with MEK or toluene. |
PubMed: | Production of Methyl Ketones from Secondary Alcohols by Cell Suspensions of C(2) to C(4)n-Alkane-Grown Bacteria. |
PubMed: | Ultrastructural studies of the dying-back process. VI. Examination of nerve fibers undergoing giant axonal degeneration in organotypic culture. |
PubMed: | Position specificity in n-hexane hydroxylation by two forms of cytochrome P-450 in rat liver microsomes. |
PubMed: | Xylene induces a cytochrome P-450 isozyme in rat liver similar to the major isozyme induced by phenobarbital. |
PubMed: | A study on biological monitoring of n-hexane exposure. |
PubMed: | Changes of n-hexane metabolites in urine of rats exposed to various concentrations of n-hexane and to its mixture with toluene or MEK. |
PubMed: | Urinary excretion of n-hexane metabolites. A comparative study in rat, rabbit and monkey. |
PubMed: | [An experimental study on the neurotoxicity of 2-octanone and 2-hexanol, a metabolite of n-hexane]. |
PubMed: | Purification and characterization of a nicotinamide adenine dinucleotide-dependent secondary alcohol dehydrogenase from Candida boidinii. |
PubMed: | Neurotoxic metabolites of "commercial hexane" in the urine of shoe factory workers. |
PubMed: | Experimental neurotoxicity and urinary metabolites of the C5-C7 aliphatic hydrocarbons used as glue solvents in shoe manufacture. |
PubMed: | Regio-selectivity of purified forms of rabbit liver microsomal cytochrome P-450 in the metabolism of benzo(a)pyrene, n-hexane and 7-ethoxyresorufin. |
PubMed: | Urinary excretion of the metabolites of n-hexane and its isomers during occupational exposure. |
PubMed: | Measurement of the urinary metabolites of N-hexane, cyclohexane and their isomers by gas chromatography. |
PubMed: | Regulation of primary alkylsulfatase induction in Pseudomonas C12B: concentration-dependent stimulation-inhibition by exogenous UTP and sodium acetate and inhibition by 1-hexanol. |
PubMed: | Microbial Oxidation of Gaseous Hydrocarbons: Production of Secondary Alcohols from Corresponding n-Alkanes by Methane-Utilizing Bacteria. |
PubMed: | Microbial production of methyl ketones. Purification and properties of a secondary alcohol dehydrogenase from yeast. |
PubMed: | Oxidation of secondary alcohols to methyl ketones by yeasts. |
PubMed: | Biotransformation of n-hexane and methyl n-butyl ketone in guinea pigs and mice. |
PubMed: | The effect of 2-hexanone and 2-hexanone metabolites on pupillomotor activity and growth. |
PubMed: | Toxicity and metabolism of methyl n-butyl ketone. |
PubMed: | Identification and quantitative analysis of the volatile substances emitted by maturing cotton in the field. |
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