Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Food Chemicals Codex Listed: | No |
Organoleptic Properties:
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents |
Wisconsin Invasive Non-native plant species |
Recommendation for clover herb distillate (melilotus officinalis) usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 25 |
Click here to view publication 25 |
| average usual ppm | average maximum ppm |
baked goods: | 0.50000 | 2.00000 |
beverages(nonalcoholic): | 0.30000 | 0.80000 |
beverages(alcoholic): | 0.50000 | 2.00000 |
breakfast cereal: | 0.50000 | 2.00000 |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | 0.50000 | 2.00000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 0.40000 | 2.00000 |
fruit ices: | - | - |
gelatins / puddings: | 0.40000 | 2.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | 0.40000 | 1.60000 |
instant coffee / tea: | 0.30000 | 1.00000 |
jams / jellies: | 0.40000 | 3.00000 |
meat products: | - | - |
milk products: | 0.40000 | 1.60000 |
nut products: | 0.40000 | 1.60000 |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | 0.20000 | 1.00000 |
snack foods: | 0.50000 | 2.00000 |
soft candy: | 0.60000 | 2.00000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | 0.30000 | 0.80000 |
Safety References:
References:
| melilotus officinalis distillate |
Pubchem (sid): | 135330290 |
Other Information:
FDA Substances Added to Food (formerly EAFUS): | View |
Wikipedia: | View |
Potential Blenders and core components note
|
For Odor |
aldehydic |
aldehydic |
iso | butyraldehyde | FL/FR |
amber |
| angelica root oil | FL/FR |
anise |
sweet | fennel seed oil | FL/FR |
anisic |
| ocimum basilicum herb oil | FL/FR |
| ocimum basilicum leaf oil america | FL/FR |
| ocimum basilicum leaf oil CO2 extract | FL/FR |
coconut |
delta- | heptalactone | FL/FR |
fatty |
(E,Z)-2,6- | dodecadienal | FL/FR |
floral |
iso | amyl salicylate | FL/FR |
beta- | damascenone | FL/FR |
| dihydrojasmone | FL/FR |
| prenyl salicylate | FL/FR |
green |
| heptanal (aldehyde C-7) | FL/FR |
3,6- | ivy carbaldehyde | FL/FR |
| melon acetal | FL/FR |
(E,E)- | sorbyl acetate | |
herbal |
| anthemis nobilis flower extract | FL/FR |
| anthemis nobilis flower oil roman | FL/FR |
sweet | basil absolute | FL/FR |
| celery ketone | FL/FR |
1,4- | cineole | FL/FR |
| clary sage oil france | FL/FR |
| hexyl salicylate | FL/FR |
| hyssop oil | FL/FR |
| linalyl octanoate | FL/FR |
curled | parsley seed oil | FL/FR |
| rosmarinus officinalis extract | FL/FR |
| rosmarinus officinalis tincture | FL/FR |
| salvia sclarea oil | FL/FR |
gamma- | valerolactone | FL/FR |
minty |
(-)- | menthone | FL/FR |
homo | menthyl acetate | FL/FR |
mossy |
| oakmoss absolute | FL/FR |
phenolic |
2,3- | dimethyl benzofuran | FL/FR |
para-alpha- | dimethyl styrene | FL/FR |
spicy |
| allspice berry absolute | FL/FR |
| allspice berry oil | FL/FR |
| allspice berry oil terpeneless | FL/FR |
| allspice leaf oil | FL/FR |
| allspice leaf oil terpeneless | FL/FR |
| allspice oil | FL/FR |
| allspice oleoresin | FL/FR |
4- | carvomenthenol | FL/FR |
beta- | caryophyllene | FL/FR |
| cascarilla oil replacer | FL/FR |
| cinnamon leaf oil | FL/FR |
terpeneless | cinnamon leaf oil | FL/FR |
| cinnamon leaf oil ceylon | FL/FR |
| clove bud absolute | FL/FR |
| clove bud essence | FL/FR |
| clove bud oil | FL/FR |
terpeneless | clove bud oil | FL/FR |
| clove bud oil CO2 extract | FL/FR |
| clove bud oleoresin | FL/FR |
| clove bud resinoid | FL/FR |
| clove leaf oil | FL/FR |
| clove leaf oil terpeneless | FL/FR |
| clove stem oil | FL/FR |
| croton eluteria bark oil | FL/FR |
| cuminaldehyde | FL/FR |
| dihydroeugenol | FL/FR |
| ethyl isoeugenol | FL/FR |
| eugenol | FL/FR |
iso | eugenol | FL/FR |
| eugenyl acetate | FL/FR |
| methyl eugenol | FR |
4- | methyl guaiacol | FL/FR |
| methyl isoeugenol | FL/FR |
| syzygium aromaticum bud extract | FL/FR |
| syzygium aromaticum tincture | FL/FR |
woody |
2- | methoxy-4-vinyl phenol | FL/FR |
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For Flavor |
|
absinthe |
| absinthe flavor | FL |
aldehydic |
iso | butyraldehyde | FL/FR |
anise |
sweet | fennel seed oil | FL/FR |
chemical |
2,3- | dimethyl benzofuran | FL/FR |
cooling |
4- | carvomenthenol | FL/FR |
1,4- | cineole | FL/FR |
homo | menthyl acetate | FL/FR |
coumarinic |
| coumarin flavor | FL |
floral |
| dihydrojasmone | FL/FR |
fruity |
| linalyl octanoate | FL/FR |
green |
| aloe vera flavor | FL |
iso | amyl salicylate | FL/FR |
| angelica root oil | FL/FR |
| celery ketone | FL/FR |
(E,Z)-2,6- | dodecadienal | FL/FR |
| heptanal (aldehyde C-7) | FL/FR |
3,6- | ivy carbaldehyde | FL/FR |
| melon acetal | FL/FR |
| oakmoss absolute | FL/FR |
| sorbyl acetate | FL |
(E,E)- | sorbyl acetate | |
herbal |
| anthemis nobilis flower extract | FL/FR |
| anthemis nobilis flower oil roman | FL/FR |
sweet | basil absolute | FL/FR |
| celery flavor | FL |
| celery seed oil distillates | FL |
| clary sage oil france | FL/FR |
| hexyl salicylate | FL/FR |
| hyssop oil | FL/FR |
| ocimum basilicum herb oil | FL/FR |
| ocimum basilicum leaf oil america | FL/FR |
| ocimum basilicum leaf oil CO2 extract | FL/FR |
curled | parsley seed oil | FL/FR |
| prenyl salicylate | FL/FR |
| rosmarinus officinalis extract | FL/FR |
| rosmarinus officinalis tincture | FL/FR |
| salvia sclarea oil | FL/FR |
lactonic |
delta- | heptalactone | FL/FR |
minty |
(-)- | menthone | FL/FR |
smoky |
2- | methoxy-4-vinyl phenol | FL/FR |
spicy |
| allspice berry absolute | FL/FR |
| allspice berry oil | FL/FR |
| allspice berry oil terpeneless | FL/FR |
| allspice flavor | FL |
| allspice leaf oil | FL/FR |
| allspice leaf oil terpeneless | FL/FR |
| allspice oil | FL/FR |
| allspice oleoresin | FL/FR |
beta- | caryophyllene | FL/FR |
| cascarilla oil replacer | FL/FR |
| cinnamon leaf oil | FL/FR |
terpeneless | cinnamon leaf oil | FL/FR |
| cinnamon leaf oil ceylon | FL/FR |
| clove bud absolute | FL/FR |
| clove bud essence | FL/FR |
terpeneless | clove bud oil | FL/FR |
| clove bud oil | FL/FR |
| clove bud oil CO2 extract | FL/FR |
| clove bud oleoresin | FL/FR |
| clove bud resinoid | FL/FR |
| clove buds | FL |
| clove flavor | FL |
| clove leaf oil | FL/FR |
| clove leaf oil terpeneless | FL/FR |
| clove stem oil | FL/FR |
| croton eluteria bark oil | FL/FR |
| cuminaldehyde | FL/FR |
| dihydroeugenol | FL/FR |
para-alpha- | dimethyl styrene | FL/FR |
| ethyl isoeugenol | FL/FR |
iso | eugenol | FL/FR |
| eugenol | FL/FR |
| eugenyl acetate | FL/FR |
| methyl isoeugenol | FL/FR |
| syzygium aromaticum bud extract | FL/FR |
| syzygium aromaticum tincture | FL/FR |
tonka |
gamma- | valerolactone | FL/FR |
vanilla |
4- | methyl guaiacol | FL/FR |
woody |
beta- | damascenone | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| brachylobus officinalis distillate | yellow sweet | clover distillate (melilotus officinalis) | | melilotus arvensis distillate | | melilotus graveolens distillate | | melilotus officinalis distillate | | melilotus officinalis fo. suaveolens distillate | | melilotus pallidus distillate | | melilotus suaveolens distillate | | sertula officinalis distillate | | trifolium officinale distillate |
Articles:
PubMed: | [Allelopathic effects of the humus soils from Betula platyphylla and Quercus liaotungensis pure plantations on 9 kinds of common shrubs and herbs]. |
PubMed: | In vitro screening of forty medicinal plant extracts from the United States Northern Great Plains for anthelmintic activity against Haemonchus contortus. |
PubMed: | Fatty acids, α-tocopherol, β-carotene, and lutein contents in forage legumes, forbs, and a grass-clover mixture. |
PubMed: | The diversity of Rhizobia, Sinorhizobia and novel non-Rhizobial Paenibacillus nodulating wild herbaceous legumes. |
PubMed: | [Soil and water losses and phosphorus output at the places between ridges in sloping peanut land under different planting modes in Yimeng mountainous area of Shandong Province, East China]. |
PubMed: | Using the pollen viability and morphology for fluoride pollution biomonitoring. |
PubMed: | Isolation and characterization of pyrene metabolizing microbial consortia from the plant rhizoplane. |
PubMed: | Pyrene effects on rhizoplane bacterial communities. |
PubMed: | Rhizobium tibeticum sp. nov., a symbiotic bacterium isolated from Trigonella archiducis-nicolai (Sirj.) Vassilcz. |
PubMed: | Stable low molecular weight RNA profiling showed variations within Sinorhizobium meliloti and Sinorhizobium medicae nodulating different legumes from the alfalfa cross-inoculation group. |
PubMed: | De-inking sludge and phosphorus effects on growth and symbiotic dinitrogen fixation in forage legumes. |
PubMed: | Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis (L.) Pallas as an alternative to Soxhlet and ultrasound-assisted extraction. |
PubMed: | The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. |
PubMed: | Effect of root death and decay on dissipation of polycyclic aromatic hydrocarbons in the rhizosphere of yellow sweet clover and tall fescue. |
PubMed: | Effectiveness of phytoremediation as a secondary treatment for polycyclic aromatic hydrocarbons (PAHs) in composted soil. |
PubMed: | Ability of cold-tolerant plants to grow in hydrocarbon-contaminated soil. |
PubMed: | [Chronic venous insufficiency: an open trial of FLEBS Crema]. |
PubMed: | Leghaemoglobin oxygenation gradients in alfalfa and yellow sweetclover nodules. |
PubMed: | Effects of Melilotus officinalis on acute inflammation. |
PubMed: | [Effectiveness of the combination of alpha tocopherol, rutin, melilotus, and centella asiatica in the treatment of patients with chronic venous insufficiency]. |
PubMed: | [Lymphedema of the upper extremity in patients operated for carcinoma of the breast: clinical experience with coumarinic extract from Melilotus officinalis]. |
PubMed: | A new oleanene glucuronide obtained from the aerial parts of Melilotus officinalis. |
PubMed: | Expression of beta-amylase from alfalfa taproots. |
PubMed: | A new oleanene glucuronide having a branched-chain sugar from Melilotus officinalis. |
PubMed: | Importance of Temperature in the Pathology of Meloidogyne hapla and M. chitwoodi on Legumes. |
PubMed: | [Contribution of a combination of alpha and beta benzopyrones, flavonoids and natural terpenes in the treatment of lymphedema of the lower limbs at the 2d stage of the surgical classification]. |
PubMed: | [Immunocorrecting, antianemia, and adaptogenic effects of polysaccharides from Melilotus officinalis]. |
PubMed: | Impact of Multi-year Cropping Regimes on Solanum tuberosum Tuber Yields in the Presence of Pratylenchus penetrans and Verticillium dahliae. |
PubMed: | Ferric Leghemoglobin in Plant-Attached Leguminous Nodules. |
PubMed: | Forage intake and digestion by cattle grazing midgrass prairie rangeland or sideoats grama/sweetclover pasture. |
PubMed: | A PCR-based method of identifying species-specific repeated DNAs. |
PubMed: | Ultrastructure of fusion products from soybean cell culture and sweet clover leaf protoplasts. |
PubMed: | Multielement residues in tissues of guinea pigs fed sweet clover grown on fly ash. |
PubMed: | [Extraction of Melilotus officinalis]. |
PubMed: | [The anti-inflammatory and anti-edematous effects of coumarins from Melilotus officinalis]. |
PubMed: | [Effect of coumarin from Melilotus officinalis on the function of the lymphatic vessel]. |
PubMed: | [Effect of coumarin from Melilotus officinalis on the blood circulation of the dog]. |
PubMed: | [Experimental lymphostatic encephalopathy as a consequence of cervical lymphangiothrombophlebitis and its therapy by coumarin from Melilotus officinalis]. |
PubMed: | [Effect of coumarin from Melilotus officinalis on the convulsion threshold of the central nervous system in rats and guinea pigs]. |
PubMed: | [Effect of pantothenic acid and pyridoxine deficiency on unconditioned reflex activity and its influencing by coumarin from Melilotus officinalis in rats]. |
PubMed: | [Unconditioned reflex activity in experimental lymphogenic encephalopathy and therapeutic effects thereon by coumarin from Melilotus officinalis]. |
PubMed: | [Influence of isoniazid (INH) on the central nervous system and the antagonism between isoniazid and pyridoxine as well as pantothenic acid and coumarin from Melilotus officinalis in rats]. |
PubMed: | [Effect of chlorpromazine on conditioned reflexes and antagonistic activity of coumarin from Melilotus officinalis]. |
PubMed: | [Effect of deficiency of pantothenic acid and pyridoxine on the function of the central nervous system and its response to coumarin from Melilotus officinalis]. |
PubMed: | [Decrease of spontaneous motility in experimental lymphogenic encephalopathy and the prophylactic activity of coumarin from Melilotus officinalis]. |
PubMed: | [Learning ability in experimental lymphogenic encephalopathy, under the influence of coumarin from Melilotus officinalis]. |
PubMed: | [Conditioned reflex function in experimental lymphogenic encephalopathy and its therapeutic modification by coumarin from Melilotus officinalis]. |
PubMed: | [LOCAL TREATMENT OF DISEASES OF VARICOSE ORIGIN. CLINICAL EXPERIENCES WITH ESBERIVEN, A MELILOTUS OFFICINALIS PREPARATION]. |
PubMed: | [Effect of aqueous extracts of Melilotus officinalis on the regenerating liver]. |
PubMed: | Biosynthesis of the coumarins. Tracer studies on coumarin formation in Hierochloe odorata and Melilotus officinalis. |
PubMed: | [Effect of Melilotus officinalis tea and its comparison with pelentan]. |
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