Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow crystals (est) |
Assay: | 96.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 88.00 to 89.00 °C. @ 760.00 mm Hg
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Boiling Point: | 334.00 to 335.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.000124 mmHg @ 25.00 °C. (est) |
Flash Point: | 282.00 °F. TCC ( 138.89 °C. )
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logP (o/w): | 2.756 (est) |
Shelf Life: | 12.00 month(s) or longer if stored properly. |
Storage: | refrigerate in tightly sealed containers. |
Soluble in: |
| water, 1.745 mg/L @ 25 °C (est) |
Organoleptic Properties:
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Odor Type: herbal |
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Odor Strength: | medium |
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| herbal celery |
Odor Description: at 100.00 %. | herbal celery |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for sedanolide usage levels up to: | | not for fragrance use.
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Recommendation for sedanolide flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
| 3-(2-methylpropyl)-3a,4,5,6-tetrahydro-3H-2-benzofuran-1-one |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 111213 |
Pubchem (sid): | 135066911 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
3- | butyl-3a,4,5,6-tetrahydro-1(3H)-isobenzofuranone | 3- | butyl-3a,4,5,6-tetrahydrophthalide | neo | cnidilide | 3-(2- | methylpropyl)-3a,4,5,6-tetrahydro-2-benzofuran-1(3H)-one | 3-(2- | methylpropyl)-3a,4,5,6-tetrahydro-3H-2-benzofuran-1-one | | tetrahydrobutyl phthalide |
Articles:
PubMed: | Chemistry, technology, and nutraceutical functions of celery (Apium graveolens L.): an overview. |
PubMed: | Isolation of the volatile fraction from Apium graveolens L. (Apiaceae) by supercritical carbon dioxide extraction and hydrodistillation: chemical composition and antifungal activity. |
PubMed: | Identification of the absorbed components and metabolites in rat plasma after oral administration of Rhizoma Chuanxiong decoction by HPLC-ESI-MS/MS. |
PubMed: | [Studies on the chemical constituents of Ligusticum sinense]. |
PubMed: | [Analysis of volatile oils of Ligusticum chuanxiong Hort. from different geographical origins by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry]. |
PubMed: | Identification and comparative quantification of bio-active phthalides in essential oils from si-wu-tang, fo-shou-san, radix angelica and rhizoma chuanxiong. |
PubMed: | [Chemical constituents of fresh celery]. |
PubMed: | GC-MS fingerprints for discrimination of Ligusticum chuanxiong from Angelica. |
PubMed: | Flavor enhancement of chicken broth from boiled celery constituents. |
PubMed: | Antibacterial activity of components from Lomatium californicum. |
PubMed: | Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. |
PubMed: | HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong. |
PubMed: | 1H and 13C NMR spectral assignments and conformational analysis of 14 19-nor-neoclerodane diterpenoids. |
PubMed: | Study of stereoselective synthesis of (+/-)-neocnidilide. |
PubMed: | Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry. |
PubMed: | Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. |
PubMed: | Separation and identification of the phthalic anhydride derivatives of Liqusticum Chuanxiong Hort by GC-MS, TLC, HPLC-DAD, and HPLC-MS. |
PubMed: | Sedanolide, a natural phthalide from celery seed oil: effect on hydrogen peroxide and tert-butyl hydroperoxide-induced toxicity in HepG2 and CaCo-2 human cell lines. |
PubMed: | Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds. |
PubMed: | [Studies on the chemical components of essential oil from the aerial parts of Ligusticum chuanxiong Hort]. |
PubMed: | [Studies on the chemical components of the rhizome of Ligusticum sinense Oliv. cv. chaxiong]. |
PubMed: | Chemoprevention of benzo[a]pyrene-induced forestomach cancer in mice by natural phthalides from celery seed oil. |
PubMed: | [Studies on the baths with crude drug: the effects of Senkyu extract as skin penetration enhancer]. |
PubMed: | cis- and trans-Neocnidilide; 1H- and 13C-NMR Data of Some Phthalides. |
PubMed: | The essential oil of Apium graveolens var. secalinum and its cercaricidal activity. |
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