Name: | boswellia carteri birdw. gum |
CAS Number: | 8050-07-5 |
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ECHA EC Number: | 232-474-1 |
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | pale yellow to amber orange tears (est) |
Food Chemicals Codex Listed: | No |
Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. )
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Soluble in: |
| water, 4.071 mg/L @ 25 °C (est) |
Organoleptic Properties:
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Odor Type: woody |
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Odor Strength: | low |
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| frankincense woody old wood fresh woody |
Odor Description: at 100.00 %. | olibanum old wood fresh woody Luebke, William tgsc, (1992) |
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Flavor Type: woody |
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| frankincense woody |
Taste Description:
| frankincense |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
European information : |
Most important hazard(s): | Xn - Harmful. |
R 20 - Harmful by inhalation. R 36/37 - Irritating to eyes and respiratory system. R 42 - May cause sensitisation by inhalation. R 48 - Danger of serious damage to health by prolonged exposure. S 23 - Do not breath fumes. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Safety References:
References:
| boswellia carteri birdw. gum |
Canada Domestic Sub. List: | 8050-07-5 |
Pubchem (sid): | 135283383 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| boswellia carteri gum | | boswellia sacra gum | | boswellia serrata gum | | frankincense crystals | | frankincense gum | | olibanum crystals | | olibanum gum |
Articles:
PubMed: | An α-Acetoxy-Tirucallic Acid Isomer Inhibits Akt/mTOR Signaling and Induces Oxidative Stress in Prostate Cancer Cells. |
PubMed: | A Randomized Clinical Trial Study: Anti-Oxidant, Anti-hyperglycemic and Anti-Hyperlipidemic Effects of Olibanum Gum in Type 2 Diabetic Patients. |
PubMed: | Effect of boswellia thurifera gum methanol extract on cytotoxicity and p53 gene expression in human breast cancer cell line. |
PubMed: | Antibacterial activity of biogenic silver nanoparticles synthesized with gum ghatti and gum olibanum: a comparative study. |
PubMed: | Extract from gum resin of Boswellia serrata decreases IA(2)-antibody in a patient with "Late onset Autoimmune Diabetes of the Adult" (LADA). |
PubMed: | Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis. |
PubMed: | The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. |
PubMed: | Effect of Boswellia serrata gum resin on the morphology of hippocampal CA1 pyramidal cells in aged rat. |
PubMed: | Effect of Boswellia serrata supplementation on blood lipid, hepatic enzymes and fructosamine levels in type2 diabetic patients. |
PubMed: | Major constituents of Boswellia carteri resin exhibit cyclooxygenase enzyme inhibition and antiproliferative activity. |
PubMed: | Identification of archaeological triterpenic resins by the non-separative techniques FTIR and 13C NMR: the case of Pistacia resin (mastic) in comparison with frankincense. |
PubMed: | Hepatoprotective prenylaromadendrane-type diterpenes from the gum resin of Boswellia carterii. |
PubMed: | Systematic review: the efficacy of herbal therapy in inflammatory bowel disease. |
PubMed: | Biotransformation of 11-keto-β-boswellic acid by Cunninghamella blakesleana. |
PubMed: | A new cytochrome P450 system from Bacillus megaterium DSM319 for the hydroxylation of 11-keto-β-boswellic acid (KBA). |
PubMed: | Acetyl-11-keto-β-boswellic acid (AKBA) inhibits human gastric carcinoma growth through modulation of the Wnt/β-catenin signaling pathway. |
PubMed: | Frankincense essential oil prepared from hydrodistillation of Boswellia sacra gum resins induces human pancreatic cancer cell death in cultures and in a xenograft murine model. |
PubMed: | Resin secretory structures of Boswellia papyrifera and implications for frankincense yield. |
PubMed: | Chemoprevention of intestinal adenomatous polyposis by acetyl-11-keto-beta-boswellic acid in APC(Min/+) mice. |
PubMed: | In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins. |
PubMed: | An in vitro study of the role of β-boswellic acid in the microtubule assembly dynamics. |
PubMed: | Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract. |
PubMed: | Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present. |
PubMed: | Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family. |
PubMed: | Proteoglycans from Boswellia serrata Roxb. and B. carteri Birdw. and identification of a proteolytic plant basic secretory protein. |
PubMed: | A novel C(28)-hydroxylated lupeolic acid suppresses the biosynthesis of eicosanoids through inhibition of cytosolic phospholipase A(2). |
PubMed: | Boswellia serrata, a potential antiinflammatory agent: an overview. |
PubMed: | Composition and antibacterial activity of the essential oils of four commercial grades of Omani luban, the oleo-gum resin of Boswellia sacra FLUECK. |
PubMed: | A novel synergistic galactomannan-based unit dosage form for sustained release of acarbose. |
PubMed: | Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells. |
PubMed: | Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets. |
PubMed: | A double blind, randomized, placebo controlled clinical study evaluates the early efficacy of aflapin in subjects with osteoarthritis of knee. |
PubMed: | Evaluation of the efficacy of ginger, Arabic gum, and Boswellia in acute and chronic renal failure. |
PubMed: | Boswellic acids from frankincense inhibit lipopolysaccharide functionality through direct molecular interference. |
PubMed: | Acetyl-11-keto-β-boswellic acid (AKBA); targeting oral cavity pathogens. |
PubMed: | Determination of major boswellic acids in plasma by high-pressure liquid chromatography/mass spectrometry. |
PubMed: | Prevention of multiple low-dose streptozotocin (MLD-STZ) diabetes in mice by an extract from gum resin of Boswellia serrata (BE). |
PubMed: | Gum resin of Boswellia serrata inhibited human monocytic (THP-1) cell activation and platelet aggregation. |
PubMed: | Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers. |
PubMed: | Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. |
PubMed: | Cellular and molecular mechanisms of anti-inflammatory effect of Aflapin: a novel Boswellia serrata extract. |
PubMed: | Identifying frankincense impact by biochemical analysis and histological examination on rats. |
PubMed: | Complete structural assignment of serratol, a cembrane-type diterpene from Boswellia serrata, and evaluation of its antiprotozoal activity. |
PubMed: | [Identification methods of terpenoid gum bases using TLC and GC/MS]. |
PubMed: | Comparative efficacy and tolerability of 5-Loxin and AflapinAgainst osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. |
PubMed: | Four new ursane-type triterpenes, olibanumols K, L, M, and N, from traditional egyptian medicine olibanum, the gum-resin of Boswellia carterii. |
PubMed: | New terpenoids, olibanumols D-G, from traditional Egyptian medicine olibanum, the gum-resin of Boswellia carterii. |
PubMed: | Safety and toxicological evaluation of Aflapin: a novel Boswellia-derived anti-inflammatory product. |
PubMed: | A review of the efficacy of traditional Iranian medicine for inflammatory bowel disease. |
PubMed: | Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense. |
PubMed: | Modulation of the immune system by Boswellia serrata extracts and boswellic acids. |
PubMed: | Complexation with phosphatidyl choline as a strategy for absorption enhancement of boswellic acid. |
PubMed: | Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer. |
PubMed: | The enhancement effect of beta-boswellic acid on hippocampal neurites outgrowth and branching (an in vitro study). |
PubMed: | Topical Boswellic acids for treatment of photoaged skin. |
PubMed: | Effects of topical boswellic acid on photo and age-damaged skin: clinical, biophysical, and echographic evaluations in a double-blind, randomized, split-face study. |
PubMed: | Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. |
PubMed: | In vivo genotoxicity evaluation of a plant based antiarthritic and anticancer therapeutic agent Boswelic acids in rodents. |
PubMed: | Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity. |
PubMed: | An update review on Commiphora molmol and related species. |
PubMed: | Bosellia serrata-induced apoptosis is related with ER stress and calcium release. |
PubMed: | In vitro screening for the tumoricidal properties of international medicinal herbs. |
PubMed: | A simple high-performance liquid chromatographic method for the estimation of boswellic acids from the market formulations containing Boswellia serrata extract. |
PubMed: | Inhibitory effect of acetyl-11-keto-beta-boswellic acid on androgen receptor by interference of Sp1 binding activity in prostate cancer cells. |
PubMed: | Bioactive constituents of myrrh and frankincense, two simultaneously prescribed gum resins in chinese traditional medicine. |
PubMed: | Comparison of the irritation potentials of Boswellia serrata gum resin and of acetyl-11-keto-beta-boswellic acid by in vitro cytotoxicity tests on human skin-derived cell lines. |
PubMed: | Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders. |
PubMed: | Commiphora molmol in human welfare (review article). |
PubMed: | Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain. |
PubMed: | Olibanum bezoar: complication of a traditional popular medicine. |
PubMed: | Compression coated systems for colonic delivery of 5-fluorouracil. |
PubMed: | Boswellic acids: biological actions and molecular targets. |
PubMed: | Characterization of 3alpha-acetyl-11-keto-alpha-boswellic acid, a pentacyclic triterpenoid inducing apoptosis in vitro and in vivo. |
PubMed: | Effect of hexane extract of Boswellia serrata oleo-gum resin on chemically induced liver damage. |
PubMed: | Natural products and anti-inflammatory activity. |
PubMed: | Effect of Boswellia serrata on intestinal motility in rodents: inhibition of diarrhoea without constipation. |
PubMed: | Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis. |
PubMed: | Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R)). |
PubMed: | Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. |
PubMed: | Extract of gum resins of Boswellia serrata L. inhibits lipopolysaccharide induced nitric oxide production in rat macrophages along with hypolipidemic property. |
PubMed: | Effects of an acetone extract of Boswellia carterii Birdw. (Burseraceae) gum resin on adjuvant-induced arthritis in lewis rats. |
PubMed: | Effects of an acetone extract of Boswellia carterii Birdw. (Burseraceae) gum resin on rats with persistent inflammation. |
PubMed: | Human genome screen to identify the genetic basis of the anti-inflammatory effects of Boswellia in microvascular endothelial cells. |
PubMed: | Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers. |
PubMed: | Headspace solid phase microextraction for screening for the presence of resins in Egyptian archaeological samples. |
PubMed: | Immunomodulatory activity of boswellic acids of Boswellia serrata Roxb. |
PubMed: | Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. |
PubMed: | Analysis of pentacyclic triterpenic acids from frankincense gum resins and related phytopharmaceuticals by high-performance liquid chromatography. Identification of lupeolic acid, a novel pentacyclic triterpene. |
PubMed: | [Study on the detecting methods of the imported materia medica--olibanum]. |
PubMed: | Acetyl-11-keto-beta-boswellic acid (AKBA) is cytotoxic for meningioma cells and inhibits phosphorylation of the extracellular-signal regulated kinase 1 and 2. |
PubMed: | Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. |
PubMed: | Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. |
PubMed: | Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. |
PubMed: | [Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases]. |
PubMed: | Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway. |
PubMed: | Cytotoxic action of acetyl-11-keto-beta-boswellic acid (AKBA) on meningioma cells. |
PubMed: | High-performance thin layer chromatographic analysis of anti-inflammatory triterpenoids from Boswellia serrata Roxb. |
PubMed: | Boswellic acids activate p42(MAPK) and p38 MAPK and stimulate Ca(2+) mobilization. |
PubMed: | Effects of gum resin of Boswellia serrata in patients with chronic colitis. |
PubMed: | Acetyl-11-keto-beta-boswellic acid, a constituent of a herbal medicine from Boswellia serrata resin, attenuates experimental ileitis. |
PubMed: | Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid. |
PubMed: | Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha. |
PubMed: | Concentration-dependent potentiating and inhibitory effects of Boswellia extracts on 5-lipoxygenase product formation in stimulated PMNL. |
PubMed: | Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. |
PubMed: | Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. |
PubMed: | Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture. |
PubMed: | Effects of Boswellia serrata gum resin in patients with ulcerative colitis. |
PubMed: | Special extract of BOSWELLIA serrata (H 15) in the treatment of rheumatoid arthritis. |
PubMed: | Mechanism of antiinflammatory actions of curcumine and boswellic acids. |
PubMed: | Anti-inflammatory activity of resins from some species of the plant family Burseraceae. |
PubMed: | Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. |
PubMed: | The effect of a plants mixture extract on liver gluconeogenesis in streptozotocin induced diabetic rats. |
PubMed: | Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of the gum resin exudate of Boswellia serrata. |
PubMed: | Studies on the metabolism of glycosaminoglycans under the influence of new herbal anti-inflammatory agents. |
PubMed: | Studies on the activity of individual plants of an antidiabetic plant mixture. |
PubMed: | CHEMICAL STANDARDIZATION OF 'KUNDUR' (Oleo-Gum-Resin of Boswellia serrata Roxb). |
PubMed: | Analgesic and psychopharmacological effects of the gum resin of Boswellia serrata. |
PubMed: | Analgesic effect of the gum resin of Boswellia serata Roxb. |
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