2-methyl butyric acid
2-methylbutyric acid
 
Notes:
Ethylmethylacetic acid is a carboxylic acid found in low amounts in normal humans (PMID 3372640) It has been described in the urine of individuals with 2-ethylhydracrylic aciduria associated with short/branched-chain acyl-CoA dehydrogenase deficiency (due to ACADSB gene mutations, OMIM 600301) (PMID 15615815) [HMDB]
  • Advanced Biotech
  • Alfrebro
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
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      Product(s):
      2 Methyl Butyric Acid
       
  • Axxence Aromatic
    • Axxence Aromatic GmbH
      We bring nature to your flavour
      Dedicated to provide the best possible quality and supply service of natural aroma ingredients.
      Axxence Aromatic is entirely dedicated to provide the best possible quality and supply service of natural aroma ingredients to the Flavour & Fragrance Industry worldwide.
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      Product(s):
      269500 2-METHYLBUTYRIC ACID Natural, Kosher
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
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      Product(s):
      10105 2-Methyl butyric acid
       
  • Berjé
    • Berje Inc.
      Where the world comes to its senses
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
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      Product(s):
      2-Methyl Butyric Acid
      2-Methyl Butyric Acid Natural
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      116-53-0 2-Methyl Butyric Acid 99.0%
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      METHYLBUTYRIC ACID, 2- FEMA 2695
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      Product(s):
      MP-024424 2-METHYL BUTYRIC ACID
      MP-030487 2-METHYL BUTYRIC ACID FLAVOUR USE
       
  • Elan Inc.
    • Elan Inc.
      Legacy of Innovation
      Highest quality natural and synthetic products.
      Elan Inc. is a privately held business that has been in operation for over 30 years. Our offices and production facility are located in Newark, NJ. We are dedicated to producing the highest quality natural and synthetic products available in the flavor and fragrance industry.
      US Email: Mr. David Pimentel
      US Email: Ms. Isabel Couto
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      US Voice: (973) 344-8014
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      Elan do Brazil Fax:55 13 3261 3726
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      Product(s):
      2-METHYL BUTYRIC ACID (natural), Kosher
      SDS
       
  • Lluch Essence
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
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      Product(s):
      A0109 2-Methylbutyric Acid, Kosher
      N0093 NAT.2-METHYLBUTYRIC ACID, Kosher
      N0094 Nat.D-2-Methylbutyric Acid, Kosher
       
  • Moellhausen
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
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      US Email: Dean Matienzo
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      US Email: Dean Matienzo - Sales Manager
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      Product(s):
      2-Methylbutyric Acid
       
  • Penta International
  • Prodasynth
    • Prodasynth
      PRODUCTEUR PAR ESSENCE
      Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.
      Today we are also proud to say, we have created an important range of Natural Molecules which can be found in our Raw Material Compendium. The versatility of our small but efficient structure is one of our main strengths when trying to fulfill our clients' requirements.
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      Product(s):
      2-METHYLBUTYRIC ACID (> 99%)
       
  • Robertet
    • Robertet, Inc.
      HOME OF NATURE, SEED TO SCENT
      HOME OF NATURE – natural ingredients from the source.
      Robertet is a leader in the production of natural ingredients with facilities in France, Bulgaria, Turkey, South Africa, India, China, New Caledonia, ... Founded in 1850, Robertet remains a family owned business (5th Generation) and one of the largest producers of aromatic extracts. Brand acquisitions include: Charabot, Sapad, Hitex.
      US Email: Customer service
      US Email: Arnaud Adrian
      Email: Flavor:
      Email: Fragrance:
      Voice: 33 4 93 40 33 66
      Fax: 33 4 93 70 68 09
      US Voice: +1.201.337.7100
      +1 212 710 4600Robertet New York Creative Center
      +1 212 245 4092Robertet New York Creative Center
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      Product(s):
      105642 2-Methyl Butyric Acid nat.
       
  • Sigma-Aldrich
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
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      Product(s):
      METHYL 2 BUTYRIC ACID FCC
       
  • Sunaux International
  • Symrise
    • Symrise AG
      Always Insiring More
      Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.
      We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success.
      US Email: Life Essentials
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      Product(s):
      600224 Methyl butyric acid-2 natural

      Useful in: brown cocoa, brown coffee, dairy, fruity red, fruity yellow, fruity tropical, fruity others.
       
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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      US Voice: (404) 524-6744
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      Product(s):
      W1356 2-methylbutyric acid
       
  • Taytonn ASCC
    • Taytonn ASCC Pte Ltd
      Supplying Asia Pacific
      We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
      Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
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      Voice: + 65 - 6861 8113
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      Product(s):
      2-Methylbutyric Acid
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      M0181 DL-2-Methylbutyric Acid >97.0%(GC)
      SDS
       
  • R C Treatt & Co Ltd
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
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      Product(s):
      2-Methylbutyric Acid
       
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas    Flavor Demo Formulas
CAS Number: 116-53-0Picture of molecule3D/inchi
Other(deleted CASRN): 600-07-7
ECHA EINECS - REACH Pre-Reg: 204-145-2
FDA UNII: PX7ZNN5GXK
Nikkaji Web: J2.000A
Beilstein Number: 1720486
MDL: MFCD00002669
CoE Number: 2002
XlogP3: 1.20 (est)
Molecular Weight: 102.13310000
Formula: C5 H10 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 255  2-methylbutyric acid
DG SANTE Food Flavourings: 08.046  2-methylbutyric acid
FEMA Number: 2695 2-methylbutyric acid
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):116-53-0 ; 2-METHYLBUTYRIC ACID
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 0.92900 to 0.93700 @  25.00 °C.
Pounds per Gallon - (est).: 7.730 to  7.797
Refractive Index: 1.40100 to 1.40800 @  20.00 °C.
Boiling Point: 176.00 to  177.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.554000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.5 ( Air = 1 )
Flash Point: 165.00 °F. TCC ( 73.89 °C. )
logP (o/w): 1.180
Shelf Life: 6.00 month(s) or longer if stored properly.
Storage: refrigerate in tightly sealed containers.
Soluble in:
 alcohol
 propylene glycol
 water, 45000 mg/L @ 20 °C (exp)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: acidic
 
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 
Substantivity: 244 hour(s) at 100.00 %
 
 pungent  acidic  cheesy roquefort cheese  cheesy  
Odor Description:
at 10.00 % in propylene glycol. 
pungent acid roquefort cheese
Luebke, William tgsc, (1989)
 
 acidic  fruity  dirty  cheesy  fermented  
Odor Description:
Acidic, fruity, dirty, cheesey with a fermented nuance
Mosciano, Gerard P&F 16, No. 2, 49, (1991)
 
 
Flavor Type: fruity
 
 fruity  dirty  acidic  dairy  buttery  cheesy  
Taste Description:
at 10.00 ppm.  
Fruity, dirty, acidic with a dairy buttery and cheesey nuance
Mosciano, Gerard P&F 16, No. 2, 49, (1991)
 
Odor and/or flavor descriptions from others (if found).
 
Bedoukian Research
2-METHYL BUTYRIC ACID ≥99.0%, Kosher
Odor Description: fruity, sour, cheesy
Used sparingly in fragrances for its natural fruity character in high dilution.
Taste Description: creamy
Used in cream cheese and chocolate flavors.
 
Symrise
Methyl butyric acid-2 natural
Odor Description: pungent acid roquefort cheese
Taste Description: acidic taste, becoming fruity at concentrations below 10 ppm
Useful in: brown cocoa, brown coffee, dairy, fruity red, fruity yellow, fruity tropical, fruity others.
 
Kingchem Laboratories
2 METHYL BUTYRIC ACID SYNTHETIC
Odor Description: Pungent acrid odor similar to Roquefort cheese
 
Moellhausen
2-METHYLBUTYRIC ACID
Odor Description: acidic, caprylic, sweat-like, somewhat cheesy
Taste Description: fruity, sour, cheesy in dilution; acidic, sweaty, berry-like
 
FCI SAS
2-METHYL BUTYRIC ACID
Odor Description: Pungent acridic cheesy
Taste Description: Nice fruity taste in dilution
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Advanced Biotech
2 METHYL BUTYRIC ACID NATURAL
Advanced Biotech
2 METHYL BUTYRIC ACID SYNTHETIC
Advanced Biotech
2-METHYL BUTYRIC ACID EEC NATURAL
98% min.
Odor: Fruity, Pleasant
Alfrebro
2-METHYL BUTYRIC ACID NATURAL
Odor: Sour, Fruity
Alfrebro
D-2-METHYL BUTYRIC ACID NATURAL
Odor: Sour, Fruity, Rancid
Anhui Haibei
2-Methyl Butyric Acid
Odor: Pungent acid roquefort cheese
Apple Flavor & Fragrance
2-Methylbutyric acid
Aromiens International
2-Methyl Butyric Acid-Chiral, Natural
Aromiens International
2-Methyl Butyric Acid, Natural
Astral Extracts
2-Methyl Butyric Acid
Augustus Oils
2 Methyl Butyric Acid
Services
Aurochemicals
2-METHYL BUTYRIC ACID, EU Natural
Aurochemicals
2-METHYL BUTYRIC ACID, US Natural
Axxence Aromatic
2-METHYLBUTYRIC ACID Natural, Kosher
Sustainability
Beijing Lys Chemicals
2-Methyl butyric acid
Berjé
2-Methyl Butyric Acid Natural
Media
Berjé
2-Methyl Butyric Acid
Best Value Chem
2-Methyl Butanoic Acid
Odor: Disagreeable, Cheesy
BOC Sciences
For experimental / research use only.
2-Methyl Butyric Acid 99.0%
Charkit Chemical
METHYLBUTYRIC ACID, 2- FEMA 2695
Citrus and Allied Essences
2-Methylbutyric Acid (natural)
Market Report
Citrus and Allied Essences
2-Methylbutyric Acid Pure
De Monchy Aromatics
2-Methylbutyric Acid
Diffusions Aromatiques
2-METHYL BUTYRIQUE ACIDE NATUREL
Diffusions Aromatiques
2-METHYL BUTYRIQUE ACIDE non OK KOSHER
Diffusions Aromatiques
2-METHYL BUTYRIQUE ACIDE
ECSA Chemicals
2-METHYL BUTYRIC ACID FLAVOUR USE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
2-METHYL BUTYRIC ACID
Elan Inc.
2-METHYL BUTYRIC ACID
(natural), Kosher
EMD Millipore
For experimental / research use only.
2-Methylbutyric Acid
Ernesto Ventós
2-METHYLBUTYRIC ACID NATURAL EXTRA
Ernesto Ventós
2-METHYLBUTYRIC ACID NATURAL FIRMENICH 904150
Odor: PUNGENT,ACRID,ROQUEFORT CHEESE
Ernesto Ventós
2-METHYLBUTYRIC ACID
Odor: DISAGREEABLE, RANCID CHEESE, APPLE
Excellentia International
2-Methyl Butyric Acid Natural
FCI SAS
2-METHYL BUTYRIC ACID NATURAL EU
Odor: Pungent acridic cheesy
FCI SAS
2-METHYL BUTYRIC ACID
Odor: Pungent acridic cheesy
Flavor: Nice fruity taste in dilution
Frutarom
2-METHYL BUTYRIC ACID
KOSHER
Flavor: Fruity, Sour, Cheesy, Acidic, Pungent
CBD Offering
Grau Aromatics
METHYL-2-BUTYRIC ACID FCC
H. Interdonati, Inc.
Optical active 2-methyl butyric acid Natural, Kosher
Featured Products
IFF
2-METHYL BUTYRIC ACID
KOSHER
Flavor: Fruity, Sour, Cheesy, Acidic, Pungent
Indukern F&F
2-METHYLBUTYRIC ACID NATURAL
Odor: CHEESE, POWERFUL, FERMENTED
Indukern F&F
2-METHYLBUTYRIC ACID
Odor: CHEESE, POWERFUL, FERMENTED
K.L. Koh Enterprise
2-METHYL BUTYRIC ACID
Kingchem Laboratories
2 METHYL BUTYRIC ACID SYNTHETIC
Odor: Pungent acrid odor similar to Roquefort cheese
Kun Shan P&A
2-Natural Methyl Butyric Acid
Lluch Essence
2-METHYL BUTIRIC ACID NAT. DEXTRO
Lluch Essence
2-METHYL BUTYRIC ACID NAT. RACEMIC
Lluch Essence
2-METHYL BUTYRIC ACID
M&U International
2-Methylbutyric Acid, Kosher
M&U International
NAT.2-METHYLBUTYRIC ACID, Kosher
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Nat.D-2-Methylbutyric Acid, Kosher
Mane
Methyl 2 Butyric Acid
Odor: Sour Fruity Cheesy
Moellhausen
2-METHYLBUTYRIC ACID
Odor: acidic, caprylic, sweat-like, somewhat cheesy
Flavor: fruity, sour, cheesy in dilution; acidic, sweaty, berry-like
Naturamole
2-methylbutyric acid 98% natural EU
OQEMA
2-Methylbutyric Acid
Pearlchem Corporation
2-Methyl Butyric Acid
Pearlchem Corporation
Natural 2-Methyl Butyric Acid
Penta International
2-METHYLBUTYRIC ACID NATURAL (OPTICALLY ACTIVE)
Penta International
2-METHYLBUTYRIC ACID NATURAL
Penta International
2-METHYLBUTYRIC ACID
Prodasynth
2-METHYLBUTYRIC ACID
(> 99%)
Odor: RANCID CHEESE, APPLE
R C Treatt & Co Ltd
2-Methylbutyric Acid
Reincke & Fichtner
2-Methyl Butyric Acid natural
Reincke & Fichtner
2-Methylbutyric Acid
Robertet
2-Methyl Butyric Acid nat.
Seasons and Harvest / Crop calendar
Santa Cruz Biotechnology
For experimental / research use only.
2-Methylbutyric Acid
Sigma-Aldrich
(±)-2-Methylbutyric acid, natural, ≥98%, FG
Odor: apple; apricot; cheese; chocolate; grape; fruity; pineapple; sour; strawberry; woody; wine-like
Certified Food Grade Products
Sigma-Aldrich
2-Methylbutyric acid, ≥98%, FG
Odor: apple; apricot; cheese; chocolate; grape; fruity; pineapple; sour; strawberry; woody; wine-like
SRS Aromatics
METHYL 2 BUTYRIC ACID FCC
Sunaux International
2-Methylbutyric Acid
Sunaux International
nat.2-Methylbutyric Acid
Sunaux International
nat.D-2-Methylbutyric Acid
Symrise
Methyl butyric acid-2 natural
Flavor: acidic taste, becoming fruity at concentrations below 10 ppm
Useful in: brown cocoa, brown coffee, dairy, fruity red, fruity yellow, fruity tropical, fruity others.
Synerzine
2-methylbutyric acid
Taytonn ASCC
2-Methylbutyric Acid
Odor: Acidic, Cheese, Pungent, Sweet
TCI AMERICA
For experimental / research use only.
DL-2-Methylbutyric Acid >97.0%(GC)
United International
2-Methyl butyric acid Nat.
Vigon International
Methyl-2 Butyric Acid Natural (Optically Active)
Vigon International
Methyl-2 Butyric Acid Natural (Racemic)
Odor: Pungent acid roquefort cheese
Vigon International
Methyl-2 Butyric Acid
WEN International
2-METHYLBUTYRIC ACID Natural
WholeChem
2-Methyl butyric acid
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
C - Corrosive.
R 21/22 - Harmful in contact with skin and if swallowed.
R 34 - Causes burns.
S 01/02 - Keep locked up and out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 27 - Take off immediately all contaminated clothing.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  3200 mg/kg
ATDAEI
1,171,1992

oral-rat LD50  1870 uL/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS MUSCULOSKELETAL: OTHER CHANGES
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 171, 1992.

Dermal Toxicity:
skin-rabbit LD50 10 ml/kg
ATDAEI
1,171,1992

skin-rabbit LD50 1460 uL/kg
BEHAVIORAL: ATAXIA SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION GASTROINTESTINAL: OTHER CHANGES
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 171, 1992.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-methyl butyric acid usage levels up to:
  0.0200 % in the fragrance concentrate.
 
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): -0.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -3.00000
fruit ices: -3.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -5.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 1, Revision 1 (FGE.01Rev 1): Branched-chain aliphatic saturated aldehydes, carboxylic acids and related esters of primary alcohols and branched-chain carboxylic acids from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission
View page or View pdf
Flavouring Group Evaluation 47, (FGE.47)[1] - Bicyclic secondary alcohols, ketones and related esters from chemical group 8 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
Flavouring Group Evaluation 01 Rev2 (FGE.01 Rev2): Branched-chain aliphatic saturated aldehydes, carboxylic acids and related esters of primary alcohols and branched-chain carboxylic acids from chemical groups 1 and 2
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 116-53-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 8314
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 3265
WGK Germany: 1
 2-methylbutanoic acid
Chemidplus: 0000116530
RTECS: EK7897000 for cas# 116-53-0
Synonyms   Articles   Notes   Search   Top
References:
Leffingwell: Chirality or Article
 2-methylbutanoic acid
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 116-53-0
Pubchem (cid): 8314
Pubchem (sid): 134975532
Flavornet: 116-53-0
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C18319
HMDB (The Human Metabolome Database): HMDB02176
FooDB: FDB008135
YMDB (Yeast Metabolome Database): YMDB01587
Export Tariff Code: 2915.60.5000
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
acidic
isobutyric acidFL/FR
 cyclohexyl acetic acidFL/FR
2-ethyl butyric acidFL/FR
alcoholic
 propyl alcoholFL/FR
aldehydic
 acetyl nonyrylFL/FR
balsamic
 cinnamyl benzoateFL/FR
bready
 coffee furanoneFL/FR
buttery
 acetoinFL/FR
 acetyl butyrylFL/FR
 acetyl isobutyrylFL/FR
 acetyl propionylFL/FR
 butyl butyryl lactateFL/FR
 butyl octanoateFL/FR
2,3-heptane dioneFL/FR
3,4-hexane dioneFL/FR
caramellic
alpha,alpha-dimethyl anisyl acetoneFL/FR
cheesy
 butyric acidFL/FR
 heptanoic acidFL/FR
2-methyl hexanoic acidFL/FR
S-(methyl thio) butyrateFL/FR
2-methyl valeric acidFL/FR
2-methyl-2-hexenoic acidFR
isovaleric acidFL/FR
 valeric acidFL/FR
coconut
 coconut decanone methylFR
delta-decalactoneFL/FR
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
gamma-octalactoneFL/FR
delta-octalactoneFL/FR
para-vanillic acidFL/FR
 waxy lactoneFL/FR
fatty
 butyl undecylenateFL/FR
(Z)-dairy lactoneFL/FR
 hexanoic acidFL/FR
4-methyl octanoic acidFL/FR
 octanoic acidFL/FR
fermented
 butyl laevo-lactateFL/FR
 valeraldehydeFL/FR
floral
 benzyl lactateFL/FR
 jasmin pyranoneFL/FR
 linalyl butyrateFL/FR
fruity
 acetoin acetateFL/FR
 butyl acetoacetateFL/FR
 cyclohexyl carboxylic acidFL/FR
gamma-decalactoneFL/FR
 ethyl lactateFL/FR
 filbert hexenoneFL/FR
 geranyl acetoacetateFL/FR
4-heptanoneFL/FR
6-hepten-1-yl 2-butenoate 
 methyl (Z)-5-octenoateFL/FR
 methyl 4-methyl valerateFL/FR
2-methyl butyl isovalerateFL/FR
 methyl butyrateFL/FR
2-methyl-5-hexen-1-yl 2-butenoate 
 prenyl hexanoateFL/FR
 prenyl isobutyrateFL/FR
 sorbyl butyrateFL/FR
green
 butyl lactateFL/FR
isobutyl methyl ketoneFL/FR
(Z)-4-heptenalFL/FR
(Z)-3-hexen-1-yl butyrateFL/FR
(E)-2-hexenalFL/FR
herbal
white cognac oilFL/FR
mushroom
1-octen-3-yl butyrateFL/FR
nutty
2-ethyl pyrazineFL/FR
 nutty quinoxalineFL/FR
soapy
 ethyl undecanoateFL/FR
tropical
delta-dodecalactoneFL/FR
waxy
2-methyl heptanoic acidFL/FR
 nonanoic acidFL/FR
2-nonanolFL/FR
delta-tetradecalactoneFL/FR
2-tridecanoneFL/FR
 undecanoic acidFL/FR
 
For Flavor
 
No flavor group found for these
 benzyl lactateFL/FR
 butyl acetoacetateFL/FR
 butyl octanoateFL/FR
 cinnamyl benzoateFL/FR
6-decenoic acidFL
alpha,alpha-dimethyl anisyl acetoneFL/FR
2,5-dithiahexaneFL
 ethyl cyclohexyl carboxylateFL
 geranyl acetoacetateFL/FR
(E,E)-2,4-heptadien-1-olFL
6-hepten-1-yl 2-butenoate 
(Z)-3-hexenoic acidFL
3-methyl crotonic acidFL
5-methyl hexanoic acidFL
3-(methyl thio) hexanalFL
S-methyl thiopropionateFL
4-methyl valeric acidFL
2-methyl-5-hexen-1-yl 2-butenoate 
 prenyl hexanoateFL/FR
 prenyl isobutyrateFL/FR
 sodium 4-methyl-2-oxovalerateFL
3-(methyl thio) methyl thiopheneFL
acidic
isobutyric acidFL/FR
2-ethyl butyric acidFL/FR
 propionic acidFL
 valeric acidFL/FR
alcoholic
 propyl alcoholFL/FR
aldehydic
 acetyl nonyrylFL/FR
alliaceous
3-tetrahydrothiophenoneFL
bitter
 glyceryl tributyrateFL
buttery
 butyl laevo-lactateFL/FR
 butyroinFL
 diacetylFL
2,3-heptane dioneFL/FR
3,4-hexane dioneFL/FR
2-methyl valeric acidFL/FR
(E)-2-pentenoic acidFL
caramellic
3-methyl butyl 2-furyl butyrateFL
cheesy
 hexanoic acidFL/FR
isovaleric acidFL/FR
coconut
delta-decalactoneFL/FR
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
delta-octalactoneFL/FR
coffee
 diisoamyl thiomalateFL
creamy
 acetoinFL/FR
 acetoin butyrateFL
 acetyl butyrylFL/FR
 acetyl isobutyrylFL/FR
 butyl butyryl lactateFL/FR
5,5-dibutyl dihydrofuran-2(3H)-oneFL
delta-dodecalactoneFL/FR
 jasmin pyranoneFL/FR
2-methyl-4-pentenoic acidFL
para-vanillic acidFL/FR
 waxy lactoneFL/FR
dairy
 methyl (Z)-5-octenoateFL/FR
4-pentenoic acidFL
fatty
(Z)-dairy lactoneFL/FR
 diacetyl trimerFL
 dimethyl sulfoxideFL
4-methyl octanoic acidFL/FR
 nonanoic acidFL/FR
(E)-2-octenoic acidFL
2-tridecanoneFL/FR
(E,E)-2,4-undecadienalFL
fermented
 methyl thio isovalerateFL
floral
 linalyl butyrateFL/FR
fruity
 acetoin acetateFL/FR
 acetyl isovalerylFL
 cyclohexyl carboxylic acidFL/FR
gamma-decalactoneFL/FR
 ethyl lactateFL/FR
 filbert hexenoneFL/FR
4-heptanoneFL/FR
 methyl 4-methyl valerateFL/FR
2-methyl butyl isovalerateFL/FR
 sorbyl butyrateFL/FR
fusel
white cognac oilFL/FR
 methyl butyrateFL/FR
green
 butyl lactateFL/FR
isobutyl methyl ketoneFL/FR
 heptanal 2,3-butane diol acetalFL
(Z)-4-heptenalFL/FR
(Z)-3-hexen-1-yl butyrateFL/FR
(E)-2-hexenalFL/FR
lactonic
gamma-octalactoneFL/FR
meaty
2-methyl 3-(methyl thio) furanFL
mushroom
1-octen-3-yl butyrateFL/FR
musty
S-(methyl thio) butyrateFL/FR
nutty
 coffee furanoneFL/FR
2-ethyl pyrazineFL/FR
 nutty quinoxalineFL/FR
oily
2-methyl hexanoic acidFL/FR
soapy
 octanoic acidFL/FR
sour
 butyric acidFL/FR
2,4-dimethyl-2-pentenoic acidFL
3-methyl valeric acidFL
sulfurous
 methyl 4-(methyl thio) butyrateFL
sweet
 cyclohexyl acetic acidFL/FR
toasted
 acetyl propionylFL/FR
waxy
 butyl undecylenateFL/FR
 ethyl undecanoateFL/FR
 heptanoic acidFL/FR
2-methyl heptanoic acidFL/FR
2-nonanolFL/FR
delta-tetradecalactoneFL/FR
 undecanoic acidFL/FR
winey
 valeraldehydeFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 angelicaFL/FR
 berryFR
 brownFL
 butterFR
 cheese roquefort cheeseFL
 chocolate cocoaFL
 cranberryFR
 creamFR
 dairyFL
 fermentedFL
 fruitFR
 huckleberryFR
 pineappleFR
 raspberryFR
 savoryFL
 strawberryFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 angelica root
Search Trop  Picture
 apple fruit
Search  PMC Picture
 apricot fruit
Search Trop  Picture
 apricot plant
Search Trop  Picture
 beer
Search  PMC Picture
 bilberry fruit
Search Trop  Picture
 bilberry fruit juice
Search Trop  Picture
 blueberry fruit juice
Search Trop  Picture
 brandy grape brandy
Search  PMC Picture
 burdock root
Search Trop  Picture
 cassia plant
Search Trop  Picture
 cayenne fruit
Search Trop  Picture
 cider
Search  PMC Picture
 cocoa
Search Trop  Picture
 coffee
Search  PMC Picture
 cranberry fruit
Search Trop  Picture
 pepper bell pepper fruit
Search Trop  Picture
 raspberry red raspberry fruit
Search Trop  Picture
 rum
Search  PMC Picture
 safflower flower
Search Trop  Picture
 strawberry wild strawberry fruit
Search Trop  Picture
 tobacco
Search Trop  Picture
 vinegar
Search  Picture
 whiskey
Search  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 ethyl methyl acetic acid
 ethylmethyl acetic acid
2-methyl butanoic acid
(1)-2-methyl butyric acid
alpha-methyl butyric acid
D-2-methyl butyric acid
 methyl butyric acid (2)
2-methyl butyric acid (natural)
2-methyl butyric acid natural
2-methyl butyric acid synthetic
2 methyl butyric acid synthetic
 methyl butyric acid-2 natural
 methyl ethyl acetic acid
 methyl-2 butyric acid
 methyl-2 butyric acid natural
 methyl-2-butyric acid FCC
2-methylbutanoic acid
2-methylbutyric acid
nat.2-methylbutyric acid
nat.D-2-methylbutyric acid
2-methylbutyric acid (natural)
2-methylbutyric acid natural
2-methylbutyric acid natural (optically active)
2-methylbutyric acid pure
 methylethyl acetic acid
Synonyms   Articles   Notes   Search   Top
Articles:
Perfumer & Flavorist: Flavor Bites: 2-Methyl Butyric Acid
PubMed: In-tube Extraction and GC-MS Analysis of Volatile Components from Wild and Cultivated sea buckthorn (Hippophae rhamnoides L. ssp. Carpatica) Berry Varieties and Juice.
PubMed: Aroma volatile compounds from two fresh pineapple varieties in china.
PubMed: Identification of aroma-active compounds in Jiashi muskmelon juice by GC-O-MS and OAV calculation.
PubMed: Identification of potent odourants in wine and brewed coffee using gas chromatography-olfactometry and comprehensive two-dimensional gas chromatography.
PubMed: The compositions of volatiles and aroma-active compounds in dried omija fruits (Schisandra chinensis Baillon) according to the cultivation areas.
PubMed: Composition of the essential oil of Argania spinosa (Sapotaceae) fruit pulp.
PubMed: Aroma-active components of Lycii fructus (kukija).
PubMed: Characterization of volatile substances in apples from Rosaceae family by headspace solid-phase microextraction followed by GC-qMS.
PubMed: Contribution to the analysis of the essential oil of Helichrysum italicum (Roth) G. Don. Determination of ester bonded acids and phenols.
PubMed: Essential oil composition of Pimpinella anisum L. fruits from various European countries.
PubMed: Characterization of aroma compounds in apple cider using solvent-assisted flavor evaporation and headspace solid-phase microextraction.
PubMed: Differentiation of aroma characteristics of pine-mushrooms (Tricholoma matsutake Sing.) of different grades using gas chromatography-olfactometry and sensory analysis.
PubMed: Characterization of aroma-active compounds in raw and cooked pine-mushrooms (Tricholoma matsutake Sing.).
PubMed: Potent odorants characterize the aroma quality of leaves and stalks in raw and boiled celery.
PubMed: Gas chromatographic-mass spectrometric analysis of essential oils from Pimpinella species gathered from Central and Northern Turkey.
PubMed: Characterization of cachaça and rum aroma.
PubMed: Odor-active constituents in fresh pineapple (Ananas comosus [L.] Merr.) by quantitative and sensory evaluation.
PubMed: Structural and Functional Analysis of the Loading Acyltransferase from Avermectin Modular Polyketide Synthase.
PubMed: Aroma compounds in Japanese sweet rice wine (Mirin) screened by aroma extract dilution analysis (AEDA).
PubMed: Characterisation of the aroma profiles of different honeys and corresponding flowers using solid-phase microextraction and gas chromatography-mass spectrometry/olfactometry.
PubMed: A new pollinating seed-consuming mutualism between Rheum nobile and a fly fungus gnat, Bradysia sp., involving pollinator attraction by a specific floral compound.
PubMed: Biodegradation of C5-C 8 fatty acids and production of aroma volatiles by Myroides sp. ZB35 isolated from activated sludge.
PubMed: Synthesis of high-quality water-soluble near-infrared-emitting CdTe quantum dots capped with 3-mercaptobutyric acid.
PubMed: Possible effects of nitric oxide synthases on odor-induced behavioral changes in mice.
PubMed: Aromatic profile of ciders by chemical quantitative, gas chromatography-olfactometry, and sensory analysis.
PubMed: Characterization of the key aroma compounds in Bartlett pear brandies by means of the sensomics concept.
PubMed: Characterization of volatile components in makgeolli, a traditional Korean rice wine, with or without pasteurization, during storage.
PubMed: Relation between HLA genes, human skin volatiles and attractiveness of humans to malaria mosquitoes.
PubMed: Cytotoxic (A549) and antimicrobial effects of Methylobacterium sp. isolate (ERI-135) from Nilgiris forest soil, India.
PubMed: Eight new diterpenoids and two new nor-diterpenoids from the stems of Croton cascarilloides.
PubMed: In-tube extraction and GC-MS analysis of volatile components from wild and cultivated sea buckthorn (Hippophae rhamnoides L. ssp. Carpatica) berry varieties and juice.
PubMed: Characterization of the formation of branched short-chain fatty acid:CoAs for bitter acid biosynthesis in hop glandular trichomes.
PubMed: Dehydropyrrolizidine alkaloids in two Cryptantha species: including two new open chain diesters one of which is amphoteric.
PubMed: 2-Methylbutyrylglycine induces lipid oxidative damage and decreases the antioxidant defenses in rat brain.
PubMed: Separation and analysis of lanthanides by isotachophoresis coupled with inductively coupled plasma mass spectrometry.
PubMed: Parallel mitral and tufted cell pathways route distinct odor information to different targets in the olfactory cortex.
PubMed: Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups.
PubMed: Production of volatile compounds by Lactobacillus sakei from branched chain α-keto acids.
PubMed: Study on pharmacokinetics and tissue distribution of pteryxin in mice by ultra-pressure liquid chromatography with tandem mass spectrometry.
PubMed: The compositions of volatiles and aroma-active compounds in dried omija fruits (Schisandra chinensis Baillon) according to the cultivation areas.
PubMed: Identification of fruity aroma-producing compounds from Chryseobacterium sp. isolated from the Western Ghats, India.
PubMed: Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces.
PubMed: Host plant shifts affect a major defense enzyme in Chrysomela lapponica.
PubMed: Prevalence, concentration, spoilage, and mitigation of Alicyclobacillus spp. in tropical and subtropical fruit juice concentrates.
PubMed: Acid stress-mediated metabolic shift in Lactobacillus sanfranciscensis LSCE1.
PubMed: FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.
PubMed: Composition of the essential oil of Argania spinosa (Sapotaceae) fruit pulp.
PubMed: Production of volatile metabolites by grape-associated microorganisms.
PubMed: Isolation and characterization of a novel 2-sec-butylphenol-degrading bacterium Pseudomonas sp. strain MS-1.
PubMed: Aroma-active components of Lycii fructus (kukija).
PubMed: Kinetic modeling of methyl butanoate in shock tube.
PubMed: Top note compounds of Chinese traditional bacteria-fermented soybean.
PubMed: Purification and characterization of antibacterial substances produced by a marine bacterium Pseudoalteromonas haloplanktis strain.
PubMed: Insertional inactivation of branched-chain alpha-keto acid dehydrogenase in Staphylococcus aureus leads to decreased branched-chain membrane fatty acid content and increased susceptibility to certain stresses.
PubMed: Contribution to the analysis of the essential oil of Helichrysum italicum (Roth) G. Don. Determination of ester bonded acids and phenols.
PubMed: Acquired multiple Acyl-CoA dehydrogenase deficiency in 10 horses with atypical myopathy.
PubMed: Cyclooxygenase-2 inhibitory effects and composition of the volatile oil from the dried roots of Lithospermum erythrorhizon.
PubMed: Innate versus learned odour processing in the mouse olfactory bulb.
PubMed: Characterization of aroma compounds in apple cider using solvent-assisted flavor evaporation and headspace solid-phase microextraction.
PubMed: Pathway analysis of branched-chain ester biosynthesis in apple using deuterium labeling and enantioselective gas chromatography-mass spectrometry.
PubMed: Differentiation of aroma characteristics of pine-mushrooms (Tricholoma matsutake Sing.) of different grades using gas chromatography-olfactometry and sensory analysis.
PubMed: Enthalpies of formation, bond dissociation energies and reaction paths for the decomposition of model biofuels: ethyl propanoate and methyl butanoate.
PubMed: Fatty acids synthesized by oral treponemes in chemically defined media.
PubMed: Stereoselective biocatalytic synthesis of (S)-2-hydroxy-2-methylbutyric acid via substrate engineering by using "thio-disguised" precursors and oxynitrilase catalysis.
PubMed: Absolute configuration of the creatonotines and callimorphines, two classes of arctiid-specific pyrrolizidine alkaloids.
PubMed: Role of branched-chain fatty acids in pH stress tolerance in Listeria monocytogenes.
PubMed: Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.
PubMed: Chemical communication in Chagas disease vectors. Source, identity, and potential function of volatiles released by the metasternal and Brindley's glands of Triatoma infestans adults.
PubMed: Requirements for the formation of a chiral template.
PubMed: Chiral templating of surfaces: adsorption of (S)-2-methylbutanoic acid on Pt(111) single-crystal surfaces.
PubMed: Potent odorants characterize the aroma quality of leaves and stalks in raw and boiled celery.
PubMed: Asymmetric oxidation by Gluconobacter oxydans.
PubMed: Cytotoxic clerodane diterpenes from Glossocarya calcicola.
PubMed: Enantiomers of cis-constrained and flexible 2-substituted GABA analogues exert opposite effects at recombinant GABA(C) receptors.
PubMed: Pharmacological profile of 4-(2',4'-difluorobiphenyl-4-yl)-2-methylbutyric acid (deoxoflobufen).
PubMed: Odor-active constituents in fresh pineapple (Ananas comosus [L.] Merr.) by quantitative and sensory evaluation.
PubMed: Identification of potent odorants in different cultivars of snake fruit [Salacca zalacca (Gaert.) Voss] using gas chromatography-olfactometry.
PubMed: Branched-chain fatty acid biosynthesis in a branched-chain amino acid aminotransferase mutant of Staphylococcus carnosus.
PubMed: Stable isotope dilution analysis of wine fermentation products by HS-SPME-GC-MS.
PubMed: 2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation.
PubMed: Role of alpha-methylacyl coenzyme A racemase in the degradation of methyl-branched alkanes by Mycobacterium sp. strain P101.
PubMed: Influence of strawberry yogurt composition on aroma release.
PubMed: Aroma extract dilution analysis of cv. Meeker (Rubus idaeus L.) red raspberries from Oregon and Washington.
PubMed: Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands.
PubMed: Total synthesis and biological evaluation of +-kalkitoxin, a cytotoxic metabolite of the cyanobacterium Lyngbya majuscula.
PubMed: Enantioselective analysis of methyl-branched alcohols and acids in rhubarb (Rheum rhabarbarum L.) stalks.
PubMed: Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate.
PubMed: 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase deficiency.
PubMed: Synthesis and evaluation of 2-amino-4-[(18)F]fluoro-2-methylbutanoic acid (FAMB): relationship of amino acid transport to tumor imaging properties of branched fluorinated amino acids.
PubMed: Gas chromatographic-olfactometric characterization of aroma compounds in two types of cashew apple nectar.
PubMed: Three new C-14 oxygenated taxanes from the wood of Taxus yunnanensis.
PubMed: [Separation and identification of thellungianin G from the root of Pimpinella thellungiana Wolff].
PubMed: Methanobrevibacter acididurans sp. nov., a novel methanogen from a sour anaerobic digester.
PubMed: Cloning and inactivation of a branched-chain-amino-acid aminotransferase gene from Staphylococcus carnosus and characterization of the enzyme.
PubMed: Biosynthesis of strawberry aroma compounds through amino acid metabolism.
PubMed: Histone deacetylase inhibitors sensitize human colonic adenocarcinoma cell lines to TNF-related apoptosis inducing ligand-mediated apoptosis.
PubMed: Correlation of long-range membrane order with temperature-dependent growth characteristics of parent and a cold-sensitive, branched-chain-fatty-acid-deficient mutant of Listeria monocytogenes.
PubMed: Competitive binding of aroma compounds by beta-cyclodextrin.
PubMed: The Principle of Maximum Chiral Discrimination: Chiral Recognition in Permethyl-beta-cyclodextrin.
PubMed: Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases.
PubMed: Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells.
PubMed: Metabolism of ethyl tiglate in apple fruits leads to the formation of small amounts of (R)-ethyl 2-methylbutanoate.
PubMed: Simultaneous enantioseparation of flobufen and its diastereomeric metabolites on ULMO, a Pirkle type chiral stationary phase.
PubMed: Odorant molecular length: one aspect of the olfactory code.
PubMed: Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species.
PubMed: Biotransformation and kinetics of excretion of tert-amyl-methyl ether in humans and rats after inhalation exposure.
PubMed: Enantioselective analysis of ketone bodies in patients with beta-ketothiolase deficiency, medium-chain acyl coenzyme A dehydrogenase deficiency and ketonemic vomiting.
PubMed: Enantiomeric synthesis of (S)-2-methylbutanoic acid methyl ester, apple flavor, using lipases in organic solvent.
PubMed: Potent aroma compounds of two red wine vinegars.
PubMed: Electron paramagnetic resonance studies of the membrane fluidity of the foodborne pathogenic psychrotroph Listeria monocytogenes.
PubMed: Biotransformation of [(12)C]- and [(13)C]-tert-amyl methyl ether and tert-amyl alcohol.
PubMed: Metabolic pathways of flobufen-a new antirheumatic and antiarthritic drug. Interspecies comparison.
PubMed: Headspace solid-phase microextraction with 1-pyrenyldiazomethane in-fibre derivatisation for analysis of faecal short-chain fatty acids.
PubMed: Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis.
PubMed: Components of the ether-insoluble resin glycoside-like fraction from Cuscuta chinensis.
PubMed: Resin glycosides. XXV. Multifidins I and II, new jalapins, from the seed of Quamoclit x multifida.
PubMed: Analogues of gamma-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) substituted in the 2 position as GABAC receptor antagonists.
PubMed: Critical role of anteiso-C15:0 fatty acid in the growth of Listeria monocytogenes at low temperatures.
PubMed: Separation of the stereoisomers of the main metabolite of a non-steroidal anti-inflammatory drug, flobufen, by chiral high-performance liquid chromatography.
PubMed: Chemical nature of larval osmeterial secretions of papilionid butterflies in the generaParnassius, Sericinus andPachliopta.
PubMed: The gp15/400 polyprotein antigen of Brugia malayi binds fatty acids and retinoids.
PubMed: Synthesis and biological activity of bile acid-derived HMG-CoA reductase inhibitors. The role of 21-methyl in recognition of HMG-CoA reductase and the ileal bile acid transport system.
PubMed: Composition of larval secretion ofChrysomela lapponica (Coleoptera, Chrysomelidae) and its dependence on host plant.
PubMed: On the structure of calonyctin A, a plant growth regulator.
PubMed: Activity of the AIB factor observed in prokaryotic and eukaryotic microorganisms.
PubMed: Scammonins VII and VIII, two resin glycosides from Convolvulus scammonia.
PubMed: Survey of conformational role of ester bonds in a cyclic depsipeptide. Study on cyclo(-L-Ala-L-Hmb-)2 by energy calculation and NMR spectroscopy.
PubMed: Nitrogen regulation of fatty acids and avermectins biosynthesis in Streptomyces avermitilis.
PubMed: Sexual dimorphism in the defensive secretion of a carabid beetle.
PubMed: Branched-chain fatty acid requirement for avermectin production by a mutant of Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity.
PubMed: Propionyl-CoA condensing enzyme from Ascaris muscle mitochondria. I. Isolation and characterization of multiple forms.
PubMed: Identification of hairpencil secretion from maleMamestra brassicae (L.) (Lepidoptera: Noctuidae) and electroantennogram studies.
PubMed: 3-Oxothiolase activities and [14C]-2-methylbutanoic acid incorporation in cultured fibroblasts from 13 cases of suspected 3-oxothiolase deficiency.
PubMed: Irritant principles of the spurge family (Euphorbiaceae). XIII. Oligocyclic and macrocyclic diterpene esters from latices of some Euphorbia species utilized as source plants of honey.
PubMed: Stereoselectivity in the 2-methylbutyrate incorporation into anteiso fatty acids in Bacillus subtilis mutants.
PubMed: Nutritional requirements of Methanomicrobium mobile.
PubMed: Effects of volatile fatty acids on propionate metabolism and gluconeogenesis in caprine hepatocytes.
PubMed: Induction of peroxisomal fatty acyl-CoA oxidase and microsomal laurate hydroxylase activities by beclobric acid and two metabolites in primary cultures of rat hepatocytes.
PubMed: Biosynthesis of mevinolin, a hypocholesterolemic fungal metabolite, in Aspergillus terreus.
PubMed: Biochemical changes during the aerobic-anaerobic transition in Ascaris suum larvae.
PubMed: Influence of oral intake of seven different antibiotics on faecal short-chain fatty acid excretion in healthy subjects.
PubMed: Gas-liquid chromatographic separation of enantiomers as their diastereomeric derivatives, illustrated with 2-methylbutyric acid.
PubMed: Biosynthesis of monensins A and B: the role of isoleucine.
PubMed: Feedlot performance and carcass characteristics of steers fed diets containing ammonium salts of the branched-chain fatty acids and valeric acid.
PubMed: Supplementation of dairy cow diets with ammonium salts of volatile fatty acids.
PubMed: Synthesis of stereoisomers of 8-methyl-2-decanol and esters attractive to severalDiabrotica sp.
PubMed: Use of predator odors as repellents to reduce feeding damage by herbivores : I. Snowshoe hares (Lepus americanus).
PubMed: Mevinolinic acid biosynthesis by Aspergillus terreus and its relationship to fatty acid biosynthesis.
PubMed: Regional differences in carboxylesterase activity between human subcutaneous and omental adipose tissue.
PubMed: Constituents of mandibular and Dufour's glands of an australianPolyrhachis weaver ant.
PubMed: Short-chain fatty acids in intestinal content of germfree mice monocontaminated with Escherichia coli or Clostridium difficile.
PubMed: Amino acids of the Murchison meteorite: II. Five carbon acyclic primary beta-, gamma-, and delta-amino alkanoic acids.
PubMed: [Metabolism of beclobrate in rat and man].
PubMed: Stereoselectivity of 1-aminocyclopropanecarboxylate malonyltransferase toward stereoisomers of 1-amino-2-ethylcyclopropanecarboxylic acid.
PubMed: Methyl butyrate-hydrolyzing activity of hepatic triglyceride lipase from rat post-heparin plasma.
PubMed: Hydroxycarboxylic and oxocarboxylic acids in urine: products from branched-chain amino acid degradation and from ketogenesis.
PubMed: Precursor directed biosynthesis of paulomycins A and B. The effects of valine, isoleucine, isobutyric acid and 2-methylbutyric acid.
PubMed: Isoleucine synthesis by Clostridium sporogenes from propionate or alpha-methylbutyrate.
PubMed: Microbial metabolism of 1,2-propanediol studied by the Rumen Simulation Technique (Rusitec).
PubMed: Pathway of formation of branched-chain volatile fatty acids in Ascaris mitochondria.
PubMed: Larval osmeterial secretions of the swallowtails (Papilio).
PubMed: Adenosine 5'-triphosphate- yielding pathways of branched-chain amino acid fermentation by a marine spirochete.
PubMed: Carboxylesterases-amidases.
PubMed: Studies of the glycine metabolism in a patient with D-glyceric acidemia and hyperglycinemia.
PubMed: Excretion pattern of branched-chain amino acid metabolites during the course of acute infections in a patient with methylmalonic acidaemia.
PubMed: Biochemical studies in a patient with defects in the metabolism of acyl-CoA and sarcosine: another possible case of glutaric aciduria type II.
PubMed: Inhibition of the glycine cleavage system by branched-chain amino acid metabolites.
PubMed: Production of branched-chain volatile fatty acids by certain anaerobic bacteria.
PubMed: Demonstration of a new mammalian isoleucine catabolic pathway yielding an Rseries of metabolites.
PubMed: Growth factor requirements of Ruminococcus flavefaciens isolated from the rumen of cattle fed purified diets.
PubMed: Isoleucine biosynthesis from 2-methylbutyric acid by anaerobic bacteria from the rumen.
PubMed: The ultrastructure of the osmeterium and the nature of its secretion in Papilio larvae (lepidoptera).
PubMed: Volatile fatty acid requirements of cellulolytic rumen bacteria.
PubMed: Characterization of several bovine rumen bacteria isolated with a xylan medium.
PubMed: Defensive Secretion of a Caterpillar (Papilio).
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