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4-methylbenzyl alcohol
Notes:
a pulmonary metabolite of para-xylene. Cosmetic and flavouring ingredient [CCD]
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 13-28500 P-METHYL BENZYL ALCOHOL 13-28510 P-METHYL BENZYL ALCOHOL POWDER
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| CAS Number: | 589-18-4 |  3D/inchi
|
| Other(deleted CASRN): | 185532-77-8 | |
| ECHA EINECS - REACH Pre-Reg: | 209-639-1 | |
| FDA UNII: | EXZ915A627 | |
| Nikkaji Web: | J28.550A | |
| Beilstein Number: | 1856550 | |
| MDL: | MFCD00004664 | |
| XlogP3: | 1.60 (est) | |
| Molecular Weight: | 122.16690000 | |
| Formula: | C8 H10 O | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 2065 4-methylbenzyl alcohol |
| FEMA Number: | 4624 4-methylbenzyl alcohol |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 589-18-4 ; 4-METHYLBENZYL ALCOHOL |
Physical Properties:
| Appearance: | white solid (est) |
| Assay: | 97.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 61.00 to 62.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 217.00 to 218.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 116.00 to 118.00 °C. @ 20.00 mm Hg |
| Acid Value: | 1.00 max. KOH/g |
| Vapor Pressure: | 0.073000 mmHg @ 25.00 °C. |
| Flash Point: | 221.00 °F. TCC ( 105.00 °C. ) |
| logP (o/w): | 1.580 |
| Soluble in: | |
| alcohol | |
| water, 7710 mg/L @ 25 °C (exp) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Strength: | low |
| Odor Description: at 100.00 %. | mild floral |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data2 |
| CosIng: | cosmetic data |
| Cosmetic Uses: |
fragrance perfuming agents skin conditioning |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| 4-methylbenzyl alcohol 98% |
| fnfsurplus.com |
| Tolyl Alcohol Crystals |
| Inoue Perfumery |
| 4-METHYL BENZYL ALCOHOL |
| Penta International |
| P-METHYL BENZYL ALCOHOL POWDER |
| Penta International |
| P-METHYL BENZYL ALCOHOL |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 4-Methylbenzyl alcohol |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| 4-Methylbenzyl alcohol 98% |
| TCI AMERICA |
| For experimental / research use only. |
| 4-Methylbenzyl Alcohol >99.0%(GC) |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
|
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 3900 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 839, 1982. oral-mouse LD50 1400 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 347, 1962. intraperitoneal-mouse LD50 324 mg/kg Yakugaku Zasshi. Journal of Pharmacy. Vol. 104, Pg. 793, 1984. | |
| Dermal Toxicity: | |
|
skin-rabbit LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 839, 1982. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic, flavor and fragrance agents | ||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| IFRA Critical Effect: | Dermal sensitization and systemic toxicity | ||
| IFRA: | View Standard | ||
| View IFRA Standards Library for complete information. | |||
| Please review Amendment 49 IFRA documentation for complete information. | |||
| IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): | |||
| Category 1: Products applied to the lips | |||
| 0.048 % | |||
| Category 2: Products applied to the axillae | |||
| 0.048 % | |||
| Category 3: Products applied to the face/body using fingertips | |||
| 0.048 % | |||
| Category 4: Products related to fine fragrance | |||
| 1.50 % | |||
| Category 5: Products applied to the face and body using the hands (palms), primarily leave-on | |||
| Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on | |||
| 0.64 % | |||
| Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on | |||
| 0.048 % | |||
| Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on | |||
| 0.048 % | |||
| Category 5D: Baby Creams, baby Oils and baby talc | |||
| 0.016 % | |||
| Category 6: Products with oral and lip exposure | |||
| 0.048 % | |||
| Category 7: Products applied to the hair with some hand contact | |||
| Category 7A: Rinse-off products applied to the hair with some hand contact | |||
| 0.048 % | |||
| Category 7B: Leave-on products applied to the hair with some hand contact | |||
| 0.048 % | |||
| Category 8: Products with significant anogenital exposure | |||
| 0.016 % | |||
| Category 9: Products with body and hand exposure, primarily rinse off | |||
| 0.53 % | |||
| Category 10: Household care products with mostly hand contact | |||
| Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) | |||
| 0.53 % | |||
| Category 10B: Household aerosol/spray products | |||
| 0.048 % | |||
| Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate | |||
| Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure | |||
| 0.016 % | |||
| Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure | |||
| 0.016 % | |||
| Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin | |||
| No Restriction | |||
| Notes: | |||
| IFRA FLAVOR REQUIREMENTS: | |||
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. | |||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 24 | |||
| Click here to view publication 24 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | - | |
| beverages(nonalcoholic): | 0.01000 | 0.10000 | |
| beverages(alcoholic): | 0.02000 | 0.50000 | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | 0.01000 | 0.50000 | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | - | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 589-18-4 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 11505 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| (4-methylphenyl)methanol | |
| Chemidplus: | 0000589184 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | DO9370000 for cas# 589-18-4 |
References:
| (4-methylphenyl)methanol | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 11505 |
| Pubchem (sid): | 134976538 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C06757 |
| HMDB (The Human Metabolome Database): | HMDB41609 |
| FooDB: | FDB021764 |
| Export Tariff Code: | 2906.29.6000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| FAO: | 4-Methylbenzyl alcohol |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| artemisia selengensis turcz. Search Trop Picture |
Synonyms:
| benzenemethanol, 4-methyl- | |
| benzenemethanol,4-methyl- | |
| p- | cresyl alcohol |
| 4-( | hydroxymethyl) toluene |
| 4-( | hydroxymethyl)toluene |
| 4- | methyl benzyl alcohol |
| p- | methyl benzyl alcohol |
| para- | methyl benzyl alcohol |
| p- | methyl benzyl alcohol powder |
| 4- | methylbenzyl alcohol |
| p- | methylbenzyl alcohol |
| para- | methylbenzyl alcohol |
| (4- | methylphenyl)methan-1-ol |
| (4- | methylphenyl)methanol |
| p- | tolualcohol |
| para- | tolualcohol |
| p- | tolyl alcohol |
| para- | tolyl alcohol |
| p- | tolylmethanol |