Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | pale yellow liquid to solid (est) |
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 78.00 °C. @ 760.00 mm Hg
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Boiling Point: | 172.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 2.160000 mmHg @ 25.00 °C. (est) |
Flash Point: | 129.00 °F. TCC ( 53.89 °C. )
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logP (o/w): | 1.362 (est) |
Soluble in: |
| water, 661.1 mg/L @ 25 °C (est) |
Stability: |
| stable in most media |
Organoleptic Properties:
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Odor Type: green |
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| green herbal |
Odor Description: at 0.01 % in propylene glycol. | green herbal |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 10 - Flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents |
Recommendation for 2-propyl thiazole usage levels up to: | | not for fragrance use.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.085 (μg/capita/day) |
Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 160 (μg/person/day) |
Threshold of Concern: | 540 (μg/person/day) |
Structure Class: | II |
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Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| average usage mg/kg | maximum usage mg/kg |
Dairy products, excluding products of category 02.0 (01.0): | 0.40000 | 2.00000 |
Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 0.20000 | 1.00000 |
Edible ices, including sherbet and sorbet (03.0): | 0.40000 | 2.00000 |
Processed fruit (04.1): | 0.30000 | 1.50000 |
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
Confectionery (05.0): | 0.40000 | 2.00000 |
Chewing gum (05.0): | - | - |
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 0.20000 | 1.00000 |
Bakery wares (07.0): | 0.40000 | 2.00000 |
Meat and meat products, including poultry and game (08.0): | 0.10000 | 0.40000 |
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 0.10000 | 0.40000 |
Eggs and egg products (10.0): | - | - |
Sweeteners, including honey (11.0): | - | - |
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 0.20000 | 1.00000 |
Foodstuffs intended for particular nutritional uses (13.0): | 0.40000 | 2.00000 |
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 0.20000 | 1.00000 |
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 0.40000 | 2.00000 |
Ready-to-eat savouries (15.0): | 1.00000 | 5.00000 |
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 0.20000 | 1.00000 |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 21: Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29. Miscellaneous substances from chemical group 30. (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 76, (FGE.76)[1] - Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29, miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 21, Revision 1 (FGE.21Rev1): Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 Miscellaneous substances from chemical group 30 View page or View pdf |
Flavouring Group Evaluation 93 (FGE.93): Consideration of sulphur heterocyclic evaluated by JECFA (68th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl evaluated by EFSA in FGE.21Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 21, Revision 2 (FGE.21Rev2): Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29. Miscellaneous substances from chemical group 30. View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 21, Revision 3 (FGE.21Rev3): Thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 21, Revision 4 (FGE.21Rev4): Thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 21, Revision 5 (FGE.21Rev5): Thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 17626-75-4 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 87198 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 2-propyl-1,3-thiazole |
Chemidplus: | 0017626754 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
No odor group found for these |
| tagete oil rwanda | |
| ferula assa-foetida gum oil | FL/FR |
| methyl furfuryl disulfide | FL/FR |
animal |
iso | butyl quinoline | FR |
anisic |
| estragole | FL/FR |
balsamic |
| cinnamyl formate | FL/FR |
chocolate |
2,4,5- | trimethyl thiazole | FL/FR |
citrus |
iso | decyl acetate | FR |
earthy |
1- | octen-3-ol | FL/FR |
ethereal |
| acetal | FL/FR |
| ethyl 4-pentenoate | FL/FR |
| ethyl pyruvate | FL/FR |
5- | methyl-5-hexen-2-one | FL/FR |
| octanoic acid | FL/FR |
(E)-2- | octenal | FL/FR |
floral |
| dihydrorose oxide | FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
2,4- | dimethyl-3-cyclohexene-1-methanol | FR |
| geranium oil africa | FL/FR |
| geranium oil egypt | FL/FR |
| neryl formate | FL/FR |
2- | pentyl cyclopentanone | FR |
iso | phytol | FL/FR |
| reseda absolute | FR |
| rose pyran | FR |
fruity |
| hexanal propylene glycol acetal | FL/FR |
2- | pentyl furan | FL/FR |
| tropical indene | FR |
| tropical thiazole | FL/FR |
green |
iso | butyl heptanoate | FL/FR |
iso | butyl methyl ketone | FL/FR |
2-sec- | butyl thiazole | FL/FR |
| cortex pyridine | FL/FR |
| ethyl (E)-2-hexenoate | FL/FR |
| flower hexene | FR |
| geranium thiazole | FL/FR |
| heptanal (aldehyde C-7) | FL/FR |
1- | heptanol | FL/FR |
(Z)-4- | heptenal | FL/FR |
(Z)-4- | hexen-1-ol | FL/FR |
(E)-4- | hexen-1-ol | |
(Z)-3- | hexen-1-yl (E)-crotonate | FL/FR |
(Z)-3- | hexen-1-yl formate | FL/FR |
(Z)-3- | hexen-1-yl lactate | FL/FR |
(Z)-3- | hexen-1-yl phenyl acetate | FL/FR |
(Z)-3- | hexen-1-yl pyruvate | FL/FR |
(Z)-3- | hexen-1-yl tiglate | FL/FR |
4- | hexenol | FL/FR |
3- | hexenyl 2-methyl butyrate | FL/FR |
| hexyl hexanoate | FL/FR |
english | ivy leaf absolute | FR |
| melon nonenoate | FL/FR |
6- | methyl-3-hepten-2-one | FL/FR |
2,6- | nonadien-1-ol | FL/FR |
2- | octen-1-ol | FL/FR |
1- | penten-3-ol | FL/FR |
| seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
herbal |
6- | acetoxydihydrotheaspirane | FL/FR |
alpha- | amyl cinnamyl formate | FL/FR |
| anethum graveolens herb oil | FL/FR |
| anthemis nobilis flower oil roman | FL/FR |
sweet | basil absolute | FL/FR |
(+)-alpha- | campholenic aldehyde | FL/FR |
| dill weed oil reunion | FL/FR |
| dimethyl benzyl carbinyl formate | FL/FR |
cis- | herbal cyclohexane | FR |
| herbal dioxane | FR |
| herbal heptane | FR |
| hop absolute | FL/FR |
| hop oil | FL/FR |
| linalyl formate | FL/FR |
| linalyl octanoate | FL/FR |
| marigold oil mexico | FL/FR |
| melaleuca leucadendron var. cajuputi leaf oil | FL/FR |
(E)-6- | methyl-3-hepten-2-one | FL/FR |
| nonisyl formate | FR |
1- | octen-3-yl acetate | FL/FR |
| origanum oil | FL/FR |
| origanum oil greece | FL/FR |
curled | parsley herb oil | FL/FR |
| perillaldehyde | FL/FR |
| tagete oil CO2 extract | FL/FR |
| tagete oil south africa | FL/FR |
| theaspirane | FL/FR |
| thyme absolute | FL/FR |
| tricyclodecyl acetate | FR |
| viridiflorol | FL/FR |
| wormwood oil america | FL/FR |
| wormwood oil cuba | FL/FR |
| wormwood oil italy | FL/FR |
| wormwood oil poland | FL/FR |
melon |
(Z)-6- | nonen-1-ol | FL/FR |
minty |
iso | propyl tiglate | FL/FR |
(-)-iso | pulegol | FL/FR |
mossy |
| treemoss absolute | FR |
| hazelnut pyrazine | FL/FR |
nutty |
2- | acetyl-3-methyl pyrazine | FL/FR |
4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
2- | methyl-3-(methyl thio) pyrazine | FL/FR |
2,4,5- | trimethyl oxazole | FL/FR |
| vinyl sulfurol | FL/FR |
pine |
| dipentene terpene hydrocarbon byproducts | FR |
spicy |
iso | butyl angelate | FL/FR |
(-)- | cubenol | FL/FR |
| cuminaldehyde | FL/FR |
iso | cyclogeraniol (IFF) | FR |
sulfurous |
| benzothiazole | FL/FR |
| dimethyl disulfide | FL/FR |
| dimethyl sulfide | FL/FR |
| grapefruit menthane | FL/FR |
| lychee mercaptan acetate | FL/FR |
| methyl 3-(methyl thio) propionate | FL/FR |
3-( | methyl thio) hexanol | FL/FR |
1- | furfuryl pyrrole | FL/FR |
| mesityl oxide | FL/FR |
| methional | FL/FR |
| tetrahydrofurfuryl alcohol | FL/FR |
waxy |
| methyl octanoate | FL/FR |
woody |
alpha- | thujene | |
| verdoxan | FR |
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For Flavor |
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No flavor group found for these |
6- | acetoxydihydrotheaspirane | FL/FR |
(E)- | aconitic acid | FL |
alpha- | amyl cinnamyl formate | FL/FR |
iso | butyl heptanoate | FL/FR |
iso | butyl mercaptan | FL |
4- | butyl thiazole | FL |
2-sec- | butyl thiazole | FL/FR |
2-(2- | butyl)-4,5-dimethyl-3-thiazoline | FL |
| diisopropyl sulfide | FL |
| dimethyl benzyl carbinyl formate | FL/FR |
| ethyl 4-pentenoate | FL/FR |
2- | ethyl-4,5-dimethyl oxazole | FL |
| fig leaf absolute | FL |
(E,E)-2,4- | hexadien-1-ol | FL |
(Z)-3- | hexen-1-yl (E)-crotonate | FL/FR |
2- | hexenal | FL |
(E)-4- | hexenal | FL |
| linalyl formate | FL/FR |
| melaleuca leucadendron var. cajuputi leaf oil | FL/FR |
2- | methyl thiazole | FL |
4-( | methyl thio) butanol | FL |
2- | methyl-3-(methyl thio) pyrazine | FL/FR |
(E)-6- | methyl-3-hepten-2-one | FL/FR |
6- | methyl-3-hepten-2-one | FL/FR |
2- | methyl-5-methoxythiazole | FL |
3- | propyl pyridine | FL |
2-iso | propyl pyridine | FL |
2-iso | propyl-3-(methyl thio) pyrazine | FL |
| seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| tagete oil rwanda | |
alpha- | thujene | |
| viridiflorol | FL/FR |
alliaceous |
| cyclopentyl mercaptan | FL |
| ferula assa-foetida gum oil | FL/FR |
2- | methyl thioacetaldehyde | FL |
3- | tetrahydrothiophenone | FL |
| tropical thiazole | FL/FR |
burnt |
2,4,5- | trimethyl oxazole | FL/FR |
coffee |
| methyl furfuryl disulfide | FL/FR |
cooling |
| theaspirane | FL/FR |
ethereal |
5- | methyl-5-hexen-2-one | FL/FR |
fatty |
(E,E)-2,4- | heptadienal | FL |
2- | octen-1-ol | FL/FR |
(E)-2- | octenal | FL/FR |
(E)-2- | octenoic acid | FL |
floral |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| geranium oil africa | FL/FR |
| geranium oil egypt | FL/FR |
fruity |
| ethyl (E)-2-hexenoate | FL/FR |
| hexanal propylene glycol acetal | FL/FR |
| hexyl hexanoate | FL/FR |
| linalyl octanoate | FL/FR |
| neryl formate | FL/FR |
| tagete oil CO2 extract | FL/FR |
| tagete oil south africa | FL/FR |
green |
iso | butyl angelate | FL/FR |
iso | butyl methyl ketone | FL/FR |
(+)-alpha- | campholenic aldehyde | FL/FR |
| cortex pyridine | FL/FR |
| dihydroxyacetophenone (mixed isomers) | FL |
| geranium thiazole | FL/FR |
| heptanal (aldehyde C-7) | FL/FR |
(Z)-4- | heptenal | FL/FR |
(E)-2- | heptenal | FL |
(Z)-4- | hexen-1-ol | FL/FR |
(E)-4- | hexen-1-ol | |
(Z)-3- | hexen-1-yl formate | FL/FR |
(Z)-3- | hexen-1-yl lactate | FL/FR |
(Z)-3- | hexen-1-yl phenyl acetate | FL/FR |
(Z)-3- | hexen-1-yl pyruvate | FL/FR |
(Z)-3- | hexen-1-yl tiglate | FL/FR |
3- | hexenyl 2-methyl butyrate | FL/FR |
| melon nonenoate | FL/FR |
| methyl octanoate | FL/FR |
3-(5- | methyl-2-furyl) butanal | FL |
2,6- | nonadien-1-ol | FL/FR |
2,4- | octadienal | FL |
1- | octen-3-yl acetate | FL/FR |
4- | penten-1-yl acetate | FL |
1- | penten-3-ol | FL/FR |
2- | pentyl furan | FL/FR |
2- | propyl pyrazine | FL |
iso | propyl tiglate | FL/FR |
| propylene glycol acetone ketal | FL |
herbal |
| anethum graveolens herb oil | FL/FR |
| anthemis nobilis flower oil roman | FL/FR |
sweet | basil absolute | FL/FR |
| dill weed oil reunion | FL/FR |
| hop absolute | FL/FR |
| hop oil | FL/FR |
| marigold oil mexico | FL/FR |
| origanum oil | FL/FR |
| origanum oil greece | FL/FR |
curled | parsley herb oil | FL/FR |
| thyme absolute | FL/FR |
| wormwood oil america | FL/FR |
| wormwood oil cuba | FL/FR |
| wormwood oil italy | FL/FR |
| wormwood oil poland | FL/FR |
juicy |
| lychee mercaptan acetate | FL/FR |
licorice |
| estragole | FL/FR |
malty |
| yeast thiazoline | FL |
meaty |
| benzothiazole | FL/FR |
3- | mercapto-3-methyl butanol | FL |
metallic |
4- | hexenol | FL/FR |
3-( | methyl thio) hexanol | FL/FR |
minty |
(-)-iso | pulegol | FL/FR |
mushroom |
1- | octen-3-ol | FL/FR |
musty |
2- | ethoxythiazole | FL |
| hazelnut pyrazine | FL/FR |
nutty |
| acetal | FL/FR |
2- | acetyl-3-methyl pyrazine | FL/FR |
3,5- | diethyl-2-methyl pyrazine | FL |
4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| tetrahydrofurfuryl alcohol | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
| vinyl sulfurol | FL/FR |
oily |
iso | phytol | FL/FR |
onion |
2- | methyl-1,3-dithiolane | FL |
| propyl thioacetate | FL |
potato |
| mesityl oxide | FL/FR |
roasted |
| ethyl 3-(furfuryl thio) propionate | FL |
rummy |
| ethyl pyruvate | FL/FR |
soapy |
| octanoic acid | FL/FR |
solvent |
1- | heptanol | FL/FR |
spicy |
| cinnamyl formate | FL/FR |
(-)- | cubenol | FL/FR |
| cuminaldehyde | FL/FR |
| jalapeno oleoresin | FL |
| perillaldehyde | FL/FR |
sulfurous |
| dimethyl disulfide | FL/FR |
| dimethyl sulfide | FL/FR |
| furfuryl methyl sulfide | FL |
| grapefruit menthane | FL/FR |
| methyl 2-methyl-3-furyl disulfide | FL |
| methyl benzyl disulfide | FL |
| methyl thiomethyl butyrate | FL |
| potato butanone | FL |
tomato |
| methional | FL/FR |
tropical |
3- | mercaptohexyl butyrate | FL |
vegetable |
1- | furfuryl pyrrole | FL/FR |
| methyl 3-(methyl thio) propionate | FL/FR |
| radish isothiocyanate | FL |
waxy |
(Z)-6- | nonen-1-ol | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | piperidin-3-yl-1,3-benzothiazole | 2- | propyl-1,3-thiazole | 2-(N- | propyl)thiazole | 2- | propylthiazole | 2-N- | propylthiazole | | thiazole, 2-propyl- |
Articles:
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