Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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Odor Type: alliaceous |
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Odor Strength: | very high , recommend smelling in a 0.01 % solution or less |
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Substantivity: | 9 hour(s) at 100.00 % |
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| ripe onion gassy meaty sulfurous |
Odor Description: at 0.10 % in propylene glycol. | strong ripe onion gassy meaty sulfurous Luebke, William tgsc, 1993) |
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| onion sharp pungent meaty sulfurous brothy chicken |
Odor Description: at 0.01 % in ethyl alcohol. | Onion, sharp and pungent, meaty sulfurous, brothy chicken and poultry-like Mosciano, Gerard P&F 24, No. 6, 10, (1999) |
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Flavor Type: eggy |
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| eggy egg yolk sulfurous chicken leek onion |
Taste Description: at 50.00 - 500.00 ppm. | Soft-boiled egg yolk, hydrogen sulfide, rich mouth feel, strong poultry, leek and onion-like Mosciano, Gerard P&F 24, No. 6, 10, (1999) |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 11 - Highly flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 33 - Take precautionary measures against static discharge. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
inhalation-mouse LC50 130000 mg/m3/1H BEHAVIORAL: REGIDITY
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) National Technical Information Service. Vol. OTS0571940
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Safety in Use Information:
Category: | flavoring agents |
Recommendation for isopropyl mercaptan usage levels up to: | | not for fragrance use.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | ND (μg/capita/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 18 |
Click here to view publication 18 |
| average usual ppm | average maximum ppm |
baked goods: | 0.10000 | 5.00000 |
beverages(nonalcoholic): | 0.10000 | 5.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | 0.10000 | 5.00000 |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 0.10000 | 5.00000 |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | 0.10000 | 5.00000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | 0.10000 | 5.00000 |
milk products: | 0.10000 | 5.00000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | 20.00000 | 200.00000 |
snack foods: | - | - |
soft candy: | 0.10000 | 5.00000 |
soups: | 0.10000 | 5.00000 |
sugar substitutes: | - | - |
sweet sauces: | 0.10000 | 5.00000 |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on the safety and efficacy of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups (chemical group 20) when used as flavourings for all animal species View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 75-33-2 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 6364 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 2402 |
WGK Germany: | 3 |
| propane-2-thiol |
Chemidplus: | 0000075332 |
EPA/NOAA CAMEO: | hazardous materials |
RTECS: | TZ7302000 for cas# 75-33-2 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
alliaceous |
| dimethyl trisulfide | FL/FR |
| dipropyl disulfide | FL/FR |
| ferula assa-foetida gum oil | FL/FR |
| methyl furfuryl disulfide | FL/FR |
| propyl mercaptan | FL/FR |
citrus |
| grapefruit mercaptan | FL/FR |
coffee |
| coffee difuran | FL/FR |
ethereal |
2- | methyl-1-butanol | FL/FR |
meaty |
| meaty dithiane | FL/FR |
4- | methyl nonanoic acid | FL/FR |
| dimethyl disulfide | FL/FR |
| dimethyl sulfide | FL/FR |
| ethyl 2-mercaptopropionate | FL/FR |
| ferula assa-foetida absolute | FL/FR |
| fish thiol | FL/FR |
2- | mercaptopropionic acid | FL/FR |
| methyl 3-(methyl thio) propionate | FL/FR |
4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
2- | methyl 5-(methyl thio) furan | FL/FR |
3-( | methyl thio) hexanol | FL/FR |
| onion oil | FL/FR |
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For Flavor |
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No flavor group found for these |
| allyl methyl disulfide | FL |
| allyl methyl trisulfide | FL |
| allyl propyl disulfide | FL |
| allyl propyl sulfide | FL |
| allyl propyl trisulfide | FL |
iso | amyl mercaptan | FL |
| benzyl methyl sulfide | FL |
| diethyl trisulfide | FL |
(Z+E)-2,5- | dimethyl-3-tetrahydrofuran thiol | FL |
(Z+E)-2,5- | dimethyl-3-thioacetoxytetrahydrofuran | FL |
| dipropyl sulfide | FL |
| ethyl methyl trisulfide | FL |
| ethyl propyl disulfide | FL |
| ethyl propyl trisulfide | FL |
| heptyl mercaptan | FL |
4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
2-( | methyl thio) methyl-2-butenal | FL |
2- | methyl-1-butane thiol | FL |
1,9- | nonane dithiol | FL |
| propenyl propyl disulfide | FL |
iso | propyl disulfide | FL |
2,3,5- | trithiahexane | FL |
alliaceous |
| allyl disulfide | FL |
| allyl mercaptan | FL |
| allyl thiopropionate | FL |
| benzyl mercaptan | FL |
1,3- | butane dithiol | FL |
| cyclopentyl mercaptan | FL |
| dicyclohexyl disulfide | FL |
| diethyl disulfide | FL |
| dimethyl trisulfide | FL/FR |
| dipropyl disulfide | FL/FR |
| dipropyl trisulfide | FL |
| ferula assa-foetida gum oil | FL/FR |
| leek oil | FL |
3- | mercapto-2-methyl pentanol | FL |
3- | mercapto-2-pentanone | FL |
| methyl 3-mercaptobutanoate | FL |
2- | methyl thioacetaldehyde | FL |
| propyl mercaptan | FL/FR |
cabbage |
| methyl 2-thiofuroate | FL |
citrus |
| grapefruit mercaptan | FL/FR |
coffee |
| coffee difuran | FL/FR |
| methyl furfuryl disulfide | FL/FR |
corn chip |
2- | acetyl-2-thiazoline | FL |
earthy |
1,8- | octane dithiol | FL |
ethereal |
2- | methyl-1-butanol | FL/FR |
fatty |
4- | methyl nonanoic acid | FL/FR |
2,4- | octadien-1-ol | FL |
garlic |
| allyl methyl sulfide | FL |
| garlic oleoresin | FL |
meaty |
2,6- | dimethyl thiophenol | FL |
2,5- | dimethyl-3-furan thiol | FL |
| furfuryl 2-methyl-3-furyl disulfide | FL |
| meaty dithiane | FL/FR |
3- | mercapto-2-butanone | FL |
(R,S)-2- | mercapto-3-butanol | FL |
2- | mercaptopropionic acid | FL/FR |
2- | methyl 3-(methyl thio) furan | FL |
bis(2- | methyl-3-furyl) disulfide | FL |
2- | methyl-3-tetrahydrofuran thiol | FL |
| pyrazinyl ethane thiol | FL |
ortho- | thiocresol | FL |
metallic |
2,5- | dihydroxy-1,4-dithiane | FL |
3-( | methyl thio) hexanol | FL/FR |
musty |
2- | methyl 5-(methyl thio) furan | FL/FR |
onion |
| ethyl 2-mercaptopropionate | FL/FR |
| methionol | FL |
| methyl propyl disulfide | FL |
| methyl propyl trisulfide | FL |
| propyl thioacetate | FL |
roasted |
| ethyl 3-(furfuryl thio) propionate | FL |
seafood |
1,4- | dithiane | FL |
sulfurous |
| allyl sulfide | FL |
2,3- | butane dithiol | FL |
| butyl mercaptan | FL |
| diallyl polysulfides | FL |
| diallyl tetrasulfide | FL |
| diallyl trisulfide | FL |
| dimethyl disulfide | FL/FR |
| dimethyl sulfide | FL/FR |
S- | ethyl thioacetate | FL |
| ferula assa-foetida absolute | FL/FR |
| fish thiol | FL/FR |
| furfuryl methyl sulfide | FL |
| furfuryl thiopropionate | FL |
3- | mercapto-2-methyl pentanal | FL |
| methyl 2-(methyl thio) butyrate | FL |
| methyl 2-methyl-3-furyl disulfide | FL |
| methyl thiomethyl butyrate | FL |
2- | methyl thiophene | FL |
| onion oil | FL/FR |
| onion oleoresin | FL |
vegetable |
| methyl 3-(methyl thio) propionate | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | mercaptopropane | 1- | methyl ethane thiol | 1- | methylethanethiol | 2- | propane thiol | iso | propane thiol | | propane-2-thiol | 2- | propanethiol | iso | propanethiol | 2- | propyl mercaptan | iso | propyl thiol | 2- | propylmercaptan | iso | propylmercaptan | iso | propylthiol |
Articles:
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