Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless solid (est) |
Assay: | 95.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Melting Point: | 25.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 255.00 to 256.00 °C. @ 760.00 mm Hg
|
Acid Value: | 1.00 max. KOH/g
|
Vapor Pressure: | 0.016000 mmHg @ 25.00 °C. (est) |
Flash Point: | 225.00 °F. TCC ( 107.22 °C. )
|
logP (o/w): | 0.754 (est) |
Soluble in: |
| alcohol | | water | | water, 113.3 mg/L @ 25 °C (est) |
Organoleptic Properties:
|
Odor Type: herbal |
|
Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
|
| herbal minty |
Odor Description: at 10.00 % in dipropylene glycol. | herbal minty |
|
Odor and/or flavor descriptions from others (if found). |
|
|
Cosmetic Information:
Suppliers:
Safety Information:
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
|
Dermal Toxicity: |
Not determined
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | flavoring agents |
Recommendation for piperitenone oxide usage levels up to: | | not for fragrance use.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.20 (μg/capita/day) |
Structure Class: | III |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 22 |
Click here to view publication 22 |
| average usual ppm | average maximum ppm |
baked goods: | 3.00000 | 15.00000 |
beverages(nonalcoholic): | - | - |
beverages(alcoholic): | - | - |
breakfast cereal: | 2.00000 | 10.00000 |
cheese: | 2.00000 | 10.00000 |
chewing gum: | - | - |
condiments / relishes: | 5.00000 | 25.00000 |
confectionery froastings: | - | - |
egg products: | 2.00000 | 10.00000 |
fats / oils: | 2.00000 | 10.00000 |
fish products: | 3.00000 | 15.00000 |
frozen dairy: | 5.00000 | 25.00000 |
fruit ices: | 1.00000 | 5.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | 3.00000 | 15.00000 |
poultry: | - | - |
processed fruits: | 1.00000 | 5.00000 |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | 2.00000 | 10.00000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
References:
| 1-methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 61942 |
Pubchem (sid): | 135018639 |
Pherobase: | View |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
7-oxa | bicyclo(4.1.0)heptan-2-one, 6-methyl-3-(1-methylethylidene)- | 1,2- | epoxy-p-menth-4(8)-en-3-one | 1,2- | epoxy-para-menth-4(8)-en-3-one | p- | menth-4(8)-en-3-one, 1,2-epoxy- | 6- | methyl-3-(1-methyl ethylidene)-7-oxabicyclo(4.1.0)heptan-2-one | 6- | methyl-3-(1-methylethylidene)-7-oxabicyclo(4.1.0)heptan-2-one | 1- | methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one | | rotundifolone |
Articles:
Info: | epoxides |
PubMed: | Chemical composition and antimicrobial activity of the essential oil of Plectranthus mollis (Lamiaceae) from Western Ghats Region, Karnataka, India. |
PubMed: | Discrimination of fennel chemotypes applying IR and Raman spectroscopy: discovery of a new γ-asarone chemotype. |
PubMed: | In vitro inhibition of herpes simplex virus type 1 replication by Mentha suaveolens essential oil and its main component piperitenone oxide. |
PubMed: | Antioxidant Activity and Volatile and Phenolic Profiles of Essential Oil and Different Extracts of Wild Mint (Mentha longifolia) from the Pakistani Flora. |
PubMed: | Essential oils of Micromeria dalmatica Benth., a Balkan endemic species of section Pseudomelissa. |
PubMed: | Biological activities of Eremostachys laevigata Bunge. grown in Iran. |
PubMed: | In vitro production of M. × piperita not containing pulegone and menthofuran. |
PubMed: | Essential-oil diversity of three Calamintha species from Greece. |
PubMed: | Intraspecific variability of the essential oil of Calamintha nepeta subsp. nepeta from Southern Italy (Apulia). |
PubMed: | Chemical and morphological diversity in wild populations of Mentha longifolia in Israel. |
PubMed: | Composition of the essential oil of Origanum tyttanthum from Tajikistan. |
PubMed: | Mentha longifolia in vitro cultures as safe source of flavouring ingredients. |
PubMed: | HS-SPME-GC×GC-qMS volatile metabolite profiling of Chrysolina herbacea frass and Mentha spp. leaves. |
PubMed: | Comparative study of volatile oil compositions of two Plectranthus species from northern India. |
PubMed: | Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae). |
PubMed: | Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four Mentha species. |
PubMed: | Chemical composition and larvicidal evaluation of Mentha, Salvia, and Melissa essential oils against the West Nile virus mosquito Culex pipiens. |
PubMed: | Composition and chemical variability of Mentha suaveolens ssp. suaveolens and M. suaveolens ssp. insularis from Corsica. |
PubMed: | Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils. |
PubMed: | Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice. |
PubMed: | Comparative analysis of the oil and supercritical CO2 extract of Ridolfia segetum (L.) Moris. |
PubMed: | Piperitenone oxide as toxic, repellent, and reproduction retardant toward malarial vector Anopheles stephensi (Diptera: Anophelinae). |
PubMed: | Composition of the essential oil of Mentha microphylla from the Gennargentu Mountains (Sardinia, Italy). |
PubMed: | Antibacterial and antifungal activity of essential oils of Mentha suaveolens. |
PubMed: | Activity of essential oils of three Micromeria species (Lamiaceae) against micromycetes and bacteria. |
PubMed: | Cardiovascular effects of the essential oil of Mentha x villosa and its main constituent, piperitenone oxide, in normotensive anaesthetised rats: role of the autonomic nervous system. |
PubMed: | Phytochemical study of Mentha longifolia of Morocco. |
PubMed: | Effects of piperitenone oxide on the intestinal smooth muscle of the guinea pig. |
PubMed: | Microbial transformations of some monoterpenoids and sesquiterpenoids. |
|