lepidine
p-methylquinoline
 
Notes:
Alkaloid from the seeds of Lepidium sativum (garden cress) Lepidine, or 4-methylquinoline, is a heterocyclic aromatic organic compound. Its methyl group is fairly acidic, allowing for condensations to occur at this position, especially when the nitrogen is quaternized. It is used in the preparation of certain dyes.
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      13-67900 4-METHYL QUINOLINE
       
  • Sigma-Aldrich
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
      US Email: Customer Service
      US Email: Sales
      US Voice: (404) 524-6744
      US Fax: (404) 577-1651
      Inquiry
      Products List: View
      Product(s):
      W1380 4-Methyl Quinoline
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
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      Product(s):
      L0024 Lepidine >97.0%(GC)(T)
       
  • R C Treatt & Co Ltd
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
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      Product(s):
      para-Methyl Quinoline
       
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas
CAS Number: 491-35-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 207-734-2
FDA UNII: 116169T3O8
Nikkaji Web: J1.552K
Beilstein Number: 0110926
MDL: MFCD00006784
CoE Number: 488
XlogP3: 2.60 (est)
Molecular Weight: 143.18873000
Formula: C10 H9 N
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: No longer supported by Industry (EFSA, 2011).
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FDA Mainterm (SATF):491-35-0 ; LEPIDINE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.08300 to 1.08900 @  25.00 °C.
Pounds per Gallon - (est).: 9.012 to  9.062
Refractive Index: 1.61500 to 1.62100 @  20.00 °C.
Melting Point: 9.00 °C. @ 760.00 mm Hg
Boiling Point: 264.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.018000 mmHg @ 25.00 °C. (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 2.610
Soluble in:
 alcohol
 water, 479.2 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: burnt
 
 burnt  oily  herbal  floral  sweet  
Odor Description:
at 100.00 %. 
burnt oily herbal floral sweet
 
 
Flavor Type: floral
 
 sweet  floral  oily  burnt  
Taste Description:
at 5.00 ppm in water.  
sweet floral oily slightly burnt
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Demand And Supply Chem
For experimental / research use only.
Lepidine
Penta International
4-METHYL QUINOLINE
R C Treatt & Co Ltd
para-Methyl Quinoline
Santa Cruz Biotechnology
For experimental / research use only.
Lepidine
Sigma-Aldrich
4-Methylquinoline, ≥99%
Certified Food Grade Products
Synerzine
4-Methyl Quinoline
TCI AMERICA
For experimental / research use only.
Lepidine >97.0%(GC)(T)
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  1260 mg/kg
(Moreno, 1976y)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for lepidine usage levels up to:
  0.6000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.12 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 160 (μg/person/day)
Threshold of Concern:90 (μg/person/day)
Structure Class: III
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 0.400002.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 0.200001.00000
Edible ices, including sherbet and sorbet (03.0): 0.400002.00000
Processed fruit (04.1): 0.300001.50000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 0.400002.00000
Chewing gum (05.0): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 0.200001.00000
Bakery wares (07.0): 0.400002.00000
Meat and meat products, including poultry and game (08.0): 0.100000.40000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 0.100000.40000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 0.200001.00000
Foodstuffs intended for particular nutritional uses (13.0): 0.400002.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 0.200001.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): --
Ready-to-eat savouries (15.0): 1.000005.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 0.200001.00000
Synonyms   Articles   Notes   Search   Top
Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 24 (FGE.24): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 Flavouring Group Evaluation 24, Revision 1 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 77 (FGE77) [1] - Consideration of Pyridine, Pyrrole and Quinoline Derivatives evaluated by JECFA (63rd meeting) structurally related to Pyridine, Pyrrole, Indole and Quinoline Derivatives evaluated by EFSA in FGE.24Rev1 (2008)
View page or View pdf
Scientific opinion on Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28
View page or View pdf
EPI System: View
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 491-35-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 10285
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 4-methylquinoline
Chemidplus: 0000491350
RTECS: OH0316000 for cas# 491-35-0
Synonyms   Articles   Notes   Search   Top
References:
 4-methylquinoline
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 491-35-0
Pubchem (cid): 10285
Pubchem (sid): 134976471
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB33437
FooDB: FDB011475
Export Tariff Code: 2933.40.7050
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
balsamic
balsamic
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
 cyclohexyl benzoateFL/FR
citrus
 acetaldehyde citronellyl methyl acetalFR
 agrestic specialtyFR
beta-bisabololFL/FR
2-heptanolFL/FR
 jambu flower oil brazil 
 litsea cubeba oil terpenelessFL/FR
floral
ortho-acetyl-para-cresolFL/FR
 amyl salicylateFL/FR
isoamyl salicylateFL/FR
 benzyl pivalateFL/FR
 bois de rose fragranceFR
 bois de rose oil brazilFL/FR
 bois de rose oil replacerFR
 butyl tiglateFR
 cassie absolute replacerFL/FR
 cassis cyclohexeneFR
 citronellalFL/FR
 clover fragranceFR
 coriander seed oilFL/FR
 cyclohexyl ethyl alcoholFL/FR
 cymbopogon validus leaf oilFR
 dihydroisojasmonate methyl esterFR
 dihydromyrceneFR
2,4-dimethyl-3-cyclohexene-1-methanolFR
 eau de brouts absoluteFR
 elder flower fragranceFR
 ethyl linaloolFR
 ethyl linalyl acetalFR
 geranyl acetateFL/FR
 heather fragranceFR
 heliotrope absoluteFR
 herbal pyranFR
 hexahydrofarnesyl acetoneFL/FR
 hexyl oxyacetonitrile 
 ho leaf oilFR
 ilex paraguariensis oleoresinFL/FR
beta-ionolFL/FR
 jasmin acetateFL/FR
isojasmoneFL/FR
(Z)-jasmoneFL/FR
 karo karounde absoluteFR
 karo karounde absolute replacerFR
 lavandin concrete decolorizedFR
 lavandin oilFL/FR
 lavandula angustifolia flower oilFL/FR
 lavender absolute replacerFR
 lavender oilFL/FR
 lavender oil bulgariaFL/FR
 lavender oil franceFL/FR
 lavender oil greeceFL/FR
 lavender oil replacerFR
 methyl nerate 
 nonisyl propionateFR
(Z)-beta-ocimeneFL/FR
 pelargonium graveolens flower waterFR
isophytolFL/FR
 prenyl salicylateFL/FR
 reseda absoluteFR
 reseda absolute replacerFR
 sambucus nigra flower oil CO2 extractFR
 terpinyl isobutyrateFL/FR
 tetrahydrolinalyl acetateFR
fruity
 myrtle oil replacerFR
 sambucus canadensis fruit absoluteFL/FR
green
 acetaldehyde di-(Z)-3-hexen-1-yl acetalFL/FR
 acetaldehyde ethyl phenethyl acetalFL/FR
isobutyl benzyl carbinolFL/FR
 decanal propylene glycol acetalFL/FR
 heptyl formateFL/FR
(Z)-3-hexen-1-olFL/FR
(Z)-3-hexen-1-yl angelateFR
 hexyl tiglateFL/FR
 marigold pot absoluteFL/FR
(E,E)-sorbyl acetate 
herbal
alpha-amyl cinnamyl formateFL/FR
 calendula officinalis flower oil CO2 extractFR
 cananga fruit oilFR
 carrot seed oil (daucus carota ssp. gummifer hook. fil.) spainFR
 chamomile isobutyrateFR
 chrysanthemum ketoneFR
 coriander seed absoluteFL/FR
 inula root oilFR
 lavandin flower waterFR
abrialis lavandin oilFL/FR
 lavender absolute bulgariaFL/FR
 lavender absolute franceFL/FR
 lavender fragranceFR
 lavender oil australiaFL/FR
 lavender oil terpenelessFL/FR
 lavender specialtyFR
 lavender stem oil lithuaniaFR
 marigold pot flower oilFL/FR
laevo-menthyl propionateFL/FR
 methyl cyclogeranate (Firmenich)FR
 methyl ortho-anisateFL/FR
5-methyl-3-heptanoneFL/FR
 myrtle oilFL/FR
 myrtle oil moroccoFL/FR
 nonisyl acetateFR
2,4,6-trimethyl-6-(3-methyl-2-buten-1-yl)-2-cyclohexen-1-one 
minty
homomenthyl acetateFL/FR
spicy
 cardamom seed oil CO2 extractFL/FR
 carnation absoluteFR
 carnation absolute replacerFR
 ginger root oil cochinFL/FR
 hollyberry fragranceFR
 origanum majorana leaf oilFL/FR
woody
2-decalinyl acetateFR
 woody acetateFR
 woody amber specialtyFR
 zdravetz absoluteFR
 zdravetz oilFL/FR
 
For Flavor
 
No flavor group found for these
 acetaldehyde di-(Z)-3-hexen-1-yl acetalFL/FR
ortho-acetyl-para-cresolFL/FR
alpha-amyl cinnamyl formateFL/FR
 benzyl pivalateFL/FR
 cassie absolute replacerFL/FR
 cyclohexyl benzoateFL/FR
 decanal propylene glycol acetalFL/FR
8,9-dehydrotheaspironeFL
 hexyl oxyacetonitrile 
 ilex paraguariensis oleoresinFL/FR
 jambu flower oil brazil 
 marigold pot flower oilFL/FR
laevo-menthyl propionateFL/FR
 methyl nerate 
 methyl ortho-anisateFL/FR
 myrtle oil moroccoFL/FR
 origanum majorana leaf oilFL/FR
3-pentanolFL
 terpinyl isobutyrateFL/FR
2,4,6-trimethyl-6-(3-methyl-2-buten-1-yl)-2-cyclohexen-1-one 
(E)-4-undecenalFL
 zdravetz oilFL/FR
amber
isobutyl benzyl carbinolFL/FR
aromatic
 amyl salicylateFL/FR
balsamic
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
citrus
beta-bisabololFL/FR
cooling
homomenthyl acetateFL/FR
fatty
 heptyl formateFL/FR
floral
 bois de rose oil brazilFL/FR
 citronellalFL/FR
 elderflower distillatesFL
beta-ionolFL/FR
 jasmin acetateFL/FR
fruity
2-heptanolFL/FR
5-methyl-3-heptanoneFL/FR
 sambucus canadensis fruit absoluteFL/FR
green
 acetaldehyde ethyl phenethyl acetalFL/FR
isoamyl salicylateFL/FR
 cyclohexyl ethyl alcoholFL/FR
 geranyl acetateFL/FR
 hexahydrofarnesyl acetoneFL/FR
(Z)-3-hexen-1-olFL/FR
 hexyl tiglateFL/FR
isojasmoneFL/FR
 marigold pot absoluteFL/FR
(Z)-beta-ocimeneFL/FR
(E,E)-sorbyl acetate 
 sorbyl acetateFL
herbal
 coriander seed absoluteFL/FR
 coriander seed oilFL/FR
 lavandin oilFL/FR
abrialis lavandin oilFL/FR
 lavandula angustifolia flower oilFL/FR
 lavender absolute bulgariaFL/FR
 lavender absolute franceFL/FR
 lavender oilFL/FR
 lavender oil australiaFL/FR
 lavender oil bulgariaFL/FR
 lavender oil franceFL/FR
 lavender oil greeceFL/FR
 lavender oil terpenelessFL/FR
 prenyl salicylateFL/FR
lemon
 litsea cubeba oil terpenelessFL/FR
oily
isophytolFL/FR
spicy
 cardamom seed oil CO2 extractFL/FR
 cumin oleoresinFL
 ginger root oil cochinFL/FR
 myrtle oilFL/FR
woody
(Z)-jasmoneFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 animalFR
 chypreFR
 leatherFR
 roseFR
 woodyFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 cress garden cress seed
Search Trop  Picture
 peppermint oil - up to 0.1 mg/kg
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 cincholepidine
 lepidine
4-lepidine
4-methyl quinoline
gamma-methyl quinoline
p-methyl quinoline
para-methyl quinoline
4-methylquinoline
gamma-methylquinoline
p-methylquinoline
para-methylquinoline
 quinoline, 4-methyl-
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Dehydrogenative cross-coupling reaction by cooperative transition-metal and Brønsted acid catalysis for the synthesis of β-quinolinyl α-amino acid esters.
PubMed: Biofunctional constituent isolated from Citrullus colocynthis fruits and structure-activity relationships of its analogues show acaricidal and insecticidal efficacy.
PubMed: Antinociceptive effect of some biuret derivatives on formalin test in mice.
PubMed: TiO₂ nanotube arrays prepared by anodization as an adsorbent in micro-solid-phase extraction to preconcentrate and determine nitrogen-containing polycyclic aromatic hydrocarbons in water samples.
PubMed: Antimicrobial potentials of active component isolated from Citrullus colocynthis fruits and structure-activity relationships of its analogues against foodborne bacteria.
PubMed: Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.
PubMed: Anion effects on the structures and magnetic properties of binuclear lanthanide single-molecule magnets.
PubMed: Genotoxicity risk assessment of diversely substituted quinolines using the SOS chromotest.
PubMed: 7-Hydroxyquinoline-8-carbaldehydes. 1. Ground- and excited-state long-range prototropic tautomerization.
PubMed: A novel approach to the pyridoacridine ring system: synthesis of the topoisomerase inhibitor 13-deazaascididemin.
PubMed: Integrated organic-aqueous biocatalysis and product recovery for quinaldine hydroxylation catalyzed by living recombinant Pseudomonas putida.
PubMed: One-pot synthesis of pyranocoumarins via microwave-assisted pseudo multicomponent reactions and their molecular switching properties.
PubMed: Synthesis, DNA binding, and oxidative cleavage studies of Fe(II) and Co(III) complexes containing bioactive ligands.
PubMed: Synthesis, antidepressant and antifungal evaluation of novel 2-chloro-8-methylquinoline amine derivatives.
PubMed: Physicochemical characterization of NPC 1161C, a novel antimalarial 8-aminoquinoline, in solution and solid state.
PubMed: Separation and preconcentration of trace amounts of aluminum ions in surface water samples using different analytical techniques.
PubMed: Spectroscopic studies on 2-[2-(4-methylquinolin-2-yl)hydrazono]-1,2-diphenylethanone molecule and its metal complexes.
PubMed: A bistable molecular switch driven by photoinduced hydrogen-atom transfer.
PubMed: An ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein.
PubMed: Thiazole Orange derivatives: synthesis, fluorescence properties, and labeling cancer cells.
PubMed: Toxicity in rhesus monkeys following administration of the 8-aminoquinoline 8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline (WR242511).
PubMed: Selenium-containing heterocycles: synthesis and pharmacological activities of some new 4-methylquinoline-2(1H) selenone derivatives.
PubMed: Facile, one-step production of niacin (vitamin B3) and other nitrogen-containing pharmaceutical chemicals with a single-site heterogeneous catalyst.
PubMed: Evaluation of the Spanish hot dip galvanising sector as a source of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans.
PubMed: Detection of methylquinoline transformation products in microcosm experiments and in tar oil contaminated groundwater using LC-NMR.
PubMed: Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions.
PubMed: Insertion reactions of alkynes and organic isocyanides into the palladium-carbon bond of dimetallic Fe-Pd alkoxysilyl complexes.
PubMed: Development and validation of a stability-indicating reversed-phase high performance liquid chromatography method for NPC 1161C, a novel 8-aminoquinoline anti-malarial drug.
PubMed: Ruthenium-catalyzed intermolecular coupling reactions of arylamines with ethylene and 1,3-dienes: mechanistic insight on hydroamination vs ortho-C-H bond activation.
PubMed: Modulation of Ca(2+)-dependent and Ca(2+)-independent miniature endplate potentials by phorbol ester and adenosine in frog.
PubMed: Simultaneous determination of NSO-heterocycles, homocycles and their metabolites in groundwater of tar oil contaminated sites using LC with diode array UV and fluorescence detection.
PubMed: [Antimicrobial effect of hydrazides and ilidenhydrazides of (quinoline-2-ilthio)carboxylic acids].
PubMed: Ring-substituted quinolines. Part 2: Synthesis and antimycobacterial activities of ring-substituted quinolinecarbohydrazide and ring-substituted quinolinecarboxamide analogues.
PubMed: Water-soluble molecular capsules: self-assembly and binding properties.
PubMed: Synthesis and antimycobacterial activities of ring-substituted quinolinecarboxylic acid/ester analogues. Part 1.
PubMed: Modular and tunable chemosensor scaffold for divalent zinc.
PubMed: Gene cluster of Arthrobacter ilicis Ru61a involved in the degradation of quinaldine to anthranilate: characterization and functional expression of the quinaldine 4-oxidase qoxLMS genes.
PubMed: Preparation of 7-alkylamino-2-methylquinoline-5,8-diones.
PubMed: N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs.
PubMed: Synthesis, characterization and reactions of 2-deoxo-5-deazaalloxazines.
PubMed: A fluorometric assay for the determination of 1-deoxy-D-xylulose 5-phosphate synthase activity.
PubMed: Derivatives of 8-hydroxy-2-methylquinoline are powerful prototypes for zinc sensors in biological systems.
PubMed: A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes.
PubMed: Synthesis and in vitro cytotoxicity of 2-alkylaminosubstituted quinoline derivatives.
PubMed: Anti-mutagenic structural modification by fluorine-substitution in highly mutagenic 4-methylquinoline derivatives.
PubMed: Sphingomonas sp. strain Lep1: an aerobic degrader of 4-methylquinoline.
PubMed: Synthesis of Pyrrolo[4,3,2-de]quinolines from 6,7-Dimethoxy-4-methylquinoline. Formal Total Syntheses of Damirones A and B, Batzelline C, Isobatzelline C, Discorhabdin C, and Makaluvamines A-D.
PubMed: Evaluation of selected antiprotozoal drugs in the Babesia microti-hamster model.
PubMed: Aerobic biodegradation of 4-methylquinoline by a soil bacterium.
PubMed: Potent mutagenic potential of 4-methylquinoline: metabolic and mechanistic considerations.
PubMed: Potential use of WR6026 as prophylaxis against transfusion-transmitted American trypanosomiasis.
PubMed: Side-chain hydroxylation in the metabolism of 8-aminoquinoline antiparasitic agents.
PubMed: Phase 2 efficacy trial of an oral 8-aminoquinoline (WR6026) for treatment of visceral leishmaniasis.
PubMed: Hydroxylation and biodegradation of 6-methylquinoline by pseudomonads in aqueous and nonaqueous immobilized-cell bioreactors.
PubMed: Microbial metabolism of quinoline and related compounds. XIX. Degradation of 4-methylquinoline and quinoline by Pseudomonas putida K1.
PubMed: Microbial metabolism of quinoline and related compounds. XV. Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium spec.1B: a molybdenum-containing enzyme.
PubMed: Comparison of methemoglobin formers in protection against the toxic effects of cyanide.
PubMed: Genotoxicity of fluoroquinolines and methylquinolines.
PubMed: Pharmacokinetics of the anti-leishmanian agent WR 6026 in dogs.
PubMed: Quinoline esters as potential antimalarial drugs: effect on relapses of Plasmodium cynomolgi infections in monkeys.
PubMed: Microbial degradation of quinoline and methylquinolines.
PubMed: Carcinogenicity of quinoline, 4- and 8-methylquinoline and benzoquinolines in newborn mice and rats.
PubMed: 2,2-Dialkyl-1,2-dihydroquinolines: cytochrome P-450 catalyzed N-alkylporphyrin formation, ferrochelatase inhibition, and induction of 5-aminolevulinic acid synthase activity.
PubMed: Fungal metabolism of 4-methylprimaquine.
PubMed: Metabolism of a potential 8-aminoquinoline antileishmanial drug in rat liver microsomes.
PubMed: High-performance liquid chromatographic method for the analysis of a candidate 8-aminoquinoline antileishmanial drug using oxidative electrochemical detection.
PubMed: Tumor-initiating activity of quinoline and methylated quinolines on the skin of SENCAR mice.
PubMed: Study of artificial flavouring substances for mutagenicity in the Salmonella/microsome, Basc and micronucleus tests.
PubMed: Quinoline and methylquinolines in cigarette smoke: comparative data and the effect of filtration.
PubMed: Effect of carcinogenic components of cigarette smoke on in vivo production of murine interferon.
PubMed: On the metabolism of quinoline and isoquinoline: possible molecular basis for differences in biological activities.
PubMed: Microbial transformation of nitroaromatic compounds in sewage effluent.
PubMed: Effect of sidestream tobacco smoke components on alpha/beta interferon production.
PubMed: [Antimalarial 6-aminoquinolines. XIV. 6-(4-Diethylamino-1-methylbutylamino)-4-methoxy-2-methyl- and -2,4-dimethylquinolines with variations of substituents in positions 5 and 8].
PubMed: Synthesis and antimalarial activity of 8-[(1-alkyl-4-aminobutyl)amino]-6-methoxy-4-methylquinolines.
PubMed: [Antimalarial 6-aminoquinolines. XIII. 5,8-Dialkoxyderivatives of 6-(4-diethylamino-1-methylbutylamino)-2-methyl- and 6-(4-diethylamino-1-methylbutylamino)-2,4-dimethylquinoline (author's transl)].
PubMed: Analogues of 8-[[6-(diethylamino) hexyl]amino]-6-methoxy-4-methylquinoline as candidate antileishmanial agents.
PubMed: Synthesis of 2,4-disubstituted 6-methoxy-8-aminoquinoline analogues as potential antiparasitics.
PubMed: Leishmaniasis: in search of new chemotherapeutic agents.
PubMed: Primaquine analogues: derivatives of 4-amino-2-methoxyacridine.
PubMed: [The reaction of heteroaromatic N-oxide with acid chloride and cyanide. IX. On p-tolylsulfonylation on side-chain carbon in 2-methylquinoline 1-oxide and related compounds (author's transl)].
PubMed: The antileishmanial activity of lepidines.
PubMed: Toxic interaction of mixtures of two coal conversion effluent components (resorcinol and 6-methylquinoline) to Daphnia magna.
PubMed: Antimalarials. 11. 2-Vinylogs of substituted 2-aryl-4-quinoline amino alcohols.
PubMed: Chichibabin reaction. 3. Chichibabin reaction of 7-methylquinoline and migration of the methyl group in Friedel-Crafts reaction of N-(m-tolyl)- and N-)p-tolyl)-beta-chloropropionamide (studies on the syntheses of heterocyclic compounds. CCXV.
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