Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear liquid (est) |
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 21.00 to 24.00 °C. @ 760.00 mm Hg
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Boiling Point: | 388.00 to 389.00 °C. @ 760.00 mm Hg
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Boiling Point: | 224.00 °C. @ 17.00 mm Hg
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Vapor Pressure: | 0.000030 mmHg @ 25.00 °C. (est) |
Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
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logP (o/w): | 8.173 (est) |
Shelf Life: | 12.00 month(s) or longer if stored properly. |
Storage: | refrigerate in tightly sealed containers. |
Soluble in: |
| alcohol | | water, 0.0009081 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: fatty |
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| fatty fruity oily |
Odor Description: at 100.00 %. | mild fatty fruity oily |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Safety References:
References:
Other Information:
Potential Blenders and core components note
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For Odor |
aldehydic |
iso | valeraldehyde | FL/FR |
anisic |
| amyl furoate | FL/FR |
coconut |
delta- | undecalactone | FL/FR |
creamy |
gamma- | butyrolactone | FL/FR |
ethereal |
| decyl propionate | FL/FR |
fatty |
| allyl decanoate | FL/FR |
iso | butyl undecylenate | FL/FR |
| coconut absolute | FL/FR |
(R)-gamma- | decalactone | FL/FR |
(S)-gamma- | decalactone | FL/FR |
| dodecyl butyrate | FL/FR |
| ethyl undecylenate | FL/FR |
(Z)-2- | octenal | |
(E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
floral |
alpha- | amyl cinnamaldehyde | FL/FR |
| apple blossom fragrance | FR |
| nonyl nonanoate | |
fruity |
| allyl cyclohexyl butyrate | FL/FR |
iso | amyl nonanoate | FL/FR |
(S)-gamma- | dodecalactone | FL/FR |
| dodecyl isobutyrate | FL/FR |
| ethyl 5-hydroxyoctanoate | FL/FR |
(R)-(-)-2- | heptanol | FL/FR |
| hexyl valerate | FL/FR |
| octyl heptanoate | FL/FR |
| octyl octanoate | FL/FR |
green |
beta- | bisabolenal | |
iso | propyl decanoate | FL/FR |
herbal |
| benzyl octanoate | FL/FR |
5- | methyl-3-heptanone | FL/FR |
musk |
| musk nonane | FR |
oily |
| glyceryl tripropanoate | |
| petal pyranone | FL/FR |
sulfurous |
O- | methyl S-1-methoxyhexan-3-yl carbonothioate | FL/FR |
waxy |
(Z)-4- | decen-1-ol | FL/FR |
| heptyl octanoate | FL/FR |
| methyl undecanoate | FR |
| propyl decanoate | FL/FR |
winey |
2- | hexanol | FL/FR |
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For Flavor |
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No flavor group found for these |
| allyl cyclohexyl butyrate | FL/FR |
| amyl furoate | FL/FR |
| benzyl octanoate | FL/FR |
beta- | bisabolenal | |
iso | butyl undecylenate | FL/FR |
| cocos nucifera water | FL |
(S)-gamma- | decalactone | FL/FR |
(R)-gamma- | decalactone | FL/FR |
(Z)-4- | decen-1-ol | FL/FR |
| decyl propionate | FL/FR |
(S)-gamma- | dodecalactone | FL/FR |
| dodecyl butyrate | FL/FR |
| dodecyl isobutyrate | FL/FR |
2,3- | epoxyoctanal | FL |
| ethyl (E)-3-octenoate | FL |
| ethyl 5-hydroxyoctanoate | FL/FR |
(R)-(-)-2- | heptanol | FL/FR |
2- | hexanol | FL/FR |
| hexyl valerate | FL/FR |
5- | methyl hexanoic acid | FL |
4- | methyl-2-pentenoic acid | FL |
| nonyl nonanoate | |
3,5- | octadien-2-one | FL |
(Z)-2- | octenal | |
| octyl heptanoate | FL/FR |
| octyl octanoate | FL/FR |
| oenanthic ether | FL |
| propyl decanoate | FL/FR |
iso | propyl decanoate | FL/FR |
3,5- | undecadien-2-one | FL |
acidic |
(E)-2- | hexenoic acid | FL |
bitter |
(E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
creamy |
delta- | undecalactone | FL/FR |
fatty |
| coconut absolute | FL/FR |
| ethyl undecylenate | FL/FR |
2,4- | undecadienal | FL |
fruity |
| allyl decanoate | FL/FR |
(E)-2- | decenoic acid | FL |
| methyl (E)-3-nonenoate | FL |
5- | methyl-3-heptanone | FL/FR |
iso | valeraldehyde | FL/FR |
green |
3-(5- | methyl-2-furyl) butanal | FL |
milky |
gamma- | butyrolactone | FL/FR |
oily |
| glyceryl tripropanoate | |
| petal pyranone | FL/FR |
roasted |
O- | methyl S-1-methoxyhexan-3-yl carbonothioate | FL/FR |
tropical |
alpha- | amyl cinnamaldehyde | FL/FR |
waxy |
| heptyl octanoate | FL/FR |
winey |
iso | amyl nonanoate | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| ethyl (9Z,12Z)-octadeca-9,12-dienoate | | ethyl (Z,Z)-9,12-octadecadienoate | | ethyl cis,cis-9,12-octadecadienoate | | ethyl linoleate natural | | ethyl linolelaidate | | ethyl octadeca-9,12-dienoate | | linoleic acid ethyl ester | | linoleic acid, ethyl ester | | linolelaidic acid ethyl ester | | mandenol | | nikkol VF-E | 9,12- | octadecadienoic acid (9Z,12Z)-, ethyl ester | 9,12- | octadecadienoic acid (Z,Z)-, ethyl ester | (9Z,12Z)-9,12- | octadecadienoic acid ethyl ester | (Z,Z)-9,12- | octadecadienoic acid ethyl ester | cis,cis-9,12- | octadecadienoic acid ethyl ester | (9Z,12Z)-9,12- | octadecadienoic acid, ethyl ester |
Articles:
PubMed: | Chinese yam extracts containing β-sitosterol and ethyl linoleate protect against atherosclerosis in apolipoprotein E-deficient mice and inhibit muscular expression of VCAM-1 in vitro. |
PubMed: | Ethyl linoleate from garlic attenuates lipopolysaccharide-induced pro-inflammatory cytokine production by inducing heme oxygenase-1 in RAW264.7 cells. |
PubMed: | Amauroderma rugosum (Blume & T. Nees) Torrend: Nutritional Composition and Antioxidant and Potential Anti-Inflammatory Properties. |
PubMed: | An oral male courtship pheromone terminates the response of Nasonia vitripennis females to the male-produced sex attractant. |
PubMed: | Identification of octenal-related dA and dC adducts formed by reactions with a hemin-ω-6-fat peroxidation model system. |
PubMed: | [Study on the constituents of essential oil of Shunaoxin dropping pills by GC-MS]. |
PubMed: | Salicylic acid peel incorporating triethyl citrate and ethyl linoleate in the treatment of moderate acne: a new therapeutic approach. |
PubMed: | Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. |
PubMed: | Chemometric profile of root extracts of Rhodiola imbricata Edgew. with hyphenated gas chromatography mass spectrometric technique. |
PubMed: | Feasibility of brewing makgeolli using Pichia anomala Y197-13, a non-Saccharomyces cerevisiae. |
PubMed: | [Screening and identifying of hepatoprotective compounds in paeoniae radix rubra]. |
PubMed: | Flavonoids with potent antioxidant activity found in young green barley leaves. |
PubMed: | Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride. |
PubMed: | A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-Oxoethyl)guanine in sprague-dawley rats. |
PubMed: | Enzymatic synthesis of fatty acid ethyl esters by utilizing camellia oil soapstocks and diethyl carbonate. |
PubMed: | Constituents with tyrosinase inhibitory activities from branches of Ficus erecta var. sieboldii King. |
PubMed: | Comparison of fermented soybean paste (Doenjang) prepared by different methods based on profiling of volatile compounds. |
PubMed: | Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MSn analysis. |
PubMed: | An improved method for rapidly quantifying fatty acid ethyl esters in meconium suitable for prenatal alcohol screening. |
PubMed: | Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. |
PubMed: | Quantitation of fatty acid ethyl esters in human meconium by an improved liquid chromatography/tandem mass spectrometry. |
PubMed: | Determination of eight fatty acid ethyl esters in meconium samples by headspace solid-phase microextraction and gas chromatography-mass spectrometry. |
PubMed: | The incidence of prenatal alcohol exposure in Montevideo Uruguay as determined by meconium analysis. |
PubMed: | Development of silymarin self-microemulsifying drug delivery system with enhanced oral bioavailability. |
PubMed: | Development of a novel self-microemulsifying drug delivery system for reducing HIV protease inhibitor-induced intestinal epithelial barrier dysfunction. |
PubMed: | Interaction of C(60) fullerene with lipids. |
PubMed: | Quantification of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in meconium from newborns for detection of alcohol abuse in a maternal health evaluation study. |
PubMed: | A bioactive complex to protect proteins from UV-induced oxidation in human epidermis. |
PubMed: | Kinetic study of the prooxidant effect of alpha-tocopherol. Hydrogen abstraction from lipids by alpha-tocopheroxyl radical. |
PubMed: | Identification of the antioxidation reaction products from a sinapic ester in a lipid oxidation system. |
PubMed: | Effects of phenol and natural phenolic compounds on biofilm formation by Pseudomonas aeruginosa. |
PubMed: | Liquid chromatography-tandem mass spectrometry for fatty acid ethyl esters in meconium: assessment of prenatal exposure to alcohol in two European cohorts. |
PubMed: | [Study on chemical constituents and anti-bacterial activity of volatile oil from seed of Aquilaria sinensis]. |
PubMed: | Antioxidation mechanism studies of caffeic acid: identification of antioxidation products of methyl caffeate from lipid oxidation. |
PubMed: | Biological screening of 100 plant extracts for cosmetic use (II): anti-oxidative activity and free radical scavenging activity. |
PubMed: | Fatty acid ethyl esters in meconium are associated with poorer neurodevelopmental outcomes to two years of age. |
PubMed: | Whitening effect of a dermocosmetic formulation: a randomized double-blind controlled study on melasma. |
PubMed: | Free radical scavenging of grape pomace extracts from Cabernet sauvingnon (Vitis vinifera). |
PubMed: | Prevalence of fetal ethanol exposure in a regional population-based sample by meconium analysis of fatty acid ethyl esters. |
PubMed: | Elevated fatty acid ethyl esters in meconium of sheep fetuses exposed in utero to ethanol--a new animal model. |
PubMed: | Linoleic and linolenic acids and acne vulgaris. |
PubMed: | Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris. |
PubMed: | Antioxidant mechanism studies on ferulic acid: identification of oxidative coupling products from methyl ferulate and linoleate. |
PubMed: | Lipid microencapsulation in starch. |
PubMed: | Fatty acid ethyl esters in meconium: are they biomarkers of fetal alcohol exposure and effect? |
PubMed: | Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. |
PubMed: | Effect of abomasal infusions of geometric isomers of 10,12 conjugated linoleic acid on milk fat synthesis in dairy cows. |
PubMed: | Fatty Acid ethyl esters: quantitative biomarkers for maternal alcohol consumption. |
PubMed: | Characterization of lubricity improver additive in diesel by gas chromatography-mass spectrometry. |
PubMed: | Fast autoxidation of ethyl linoleate catalyzed by [Mn(acac)3] and bipyridine: a possible drying catalyst for alkyd paints. |
PubMed: | Novel oral formulation of paclitaxel inhibits neointimal hyperplasia in a rat carotid artery injury model. |
PubMed: | Ethyl arachidonate is the predominant fatty acid ethyl ester in the brains of alcohol-intoxicated subjects at autopsy. |
PubMed: | Structural identification of new curcumin dimers and their contribution to the antioxidant mechanism of curcumin. |
PubMed: | Antioxidant mechanism of carnosic acid: structural identification of two oxidation products. |
PubMed: | Chemical studies on antioxidant mechanism of curcumin: analysis of oxidative coupling products from curcumin and linoleate. |
PubMed: | Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay. |
PubMed: | 4-Hydroxy-2-nonenal and ethyl linoleate form N(2),3-ethenoguanine under peroxidizing conditions. |
PubMed: | Formation of biocompatible reversed micellar systems using phospholipids. |
PubMed: | Differences in the fatty acid composition of fatty acid ethyl esters in organs and their secretions. |
PubMed: | The questionable role of a microsomal delta8 acyl-coA-dependent desaturase in the biosynthesis of polyunsaturated fatty acids. |
PubMed: | Acid-promoted reactions of ethyl linoleate with nitrite ions: formation and structural characterization of isomeric nitroalkene, nitrohydroxy, and novel 3-nitro-1,5-hexadiene and 1,5-dinitro-1, 3-pentadiene products. |
PubMed: | Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. |
PubMed: | Ethyl linoleate in meconium: a biomarker for prenatal ethanol exposure. |
PubMed: | Ethyl palmitate and ethyl oleate are the predominant fatty acid ethyl esters in the blood after ethanol ingestion and their synthesis is differentially influenced by the extracellular concentrations of their corresponding fatty acids. |
PubMed: | Simultaneous determination of acrolein, malonaldehyde and 4-hydroxy-2-nonenal produced from lipids oxidized with Fenton's reagent. |
PubMed: | 1'-Acetoxychavicol acetate, a superoxide anion generation inhibitor, potently inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in ICR mouse skin. |
PubMed: | Oxidized ethyl linoleate induces mucosal hypertrophy of the large intestine and affects cecal fermentation of dietary fiber in rats. |
PubMed: | Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. |
PubMed: | Turnover of ethyl-linoleate in rat plasma and its distribution in various organs. |
PubMed: | In vitro anti- and pro-oxidative effects of natural polyphenols. |
PubMed: | Inhibitory effect of 2"-O-glycosyl isovitexin and alpha-tocopherol on genotoxic glyoxal formation in a lipid peroxidation system. |
PubMed: | A comparison of the specific activities of linoleate and arachidonate in liver, heart and kidney phospholipids after feeding rats ethyl linoleate-9,10,12,13-d4. |
PubMed: | [Transformation products of vitamin E and its analog--chroman C1 in an oxidizing ethyl linoleate medium]. |
PubMed: | Ethanol-induced fatty acid ethyl ester formation in vivo and in vitro in rat lung. |
PubMed: | Arachidonic acid and linoleic acid supplementation increase prostanoid production in rats fed a butter-enriched diet. |
PubMed: | Interactions of oxidized lipids with protein. Part XVI. Interactions of oxidized ethyl linoleate with collagen. |
PubMed: | Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina. |
PubMed: | [Synthesis and antioxidative activity of structural analogs of vitamin E]. |
PubMed: | The wormicidal substances of fresh water fishes on Clonorchis sinensis VII. The effect of linoleic acid and ethyl linoleate on parasite viability. |
PubMed: | Oxidation of 1-O-(alk-1-enyl)-2,3-di-O-acylglycerols: models for plasmalogen oxidation. |
PubMed: | Reactions of oxidized lipids with protein. Part 15. Mechanism of lipoprotein formation from interactions of oxidized ethyl linoleate with egg albumin. |
PubMed: | Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats. |
PubMed: | The effect of a single oral dose of ethyl linoleate on urinary prostaglandin E2 excretion in essential fatty acid-deficient rats. |
PubMed: | Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet. |
PubMed: | Arachidonic acid, 5,8,11-eicosatrienoic acid and 5,8,11,14, 17-eicosapentaenoic acid. Dietary manipulation of the levels of these acids in rat liver and platelet phospholipids and their incorporation into human platelet lipids. |
PubMed: | Spectrophotometric detection of lipid conjugated dienes. |
PubMed: | Effects of polyunsaturated fatty acid diets on plasma lipids of patients with adrenomultineuronal degeneration, hepatosplenomegaly and fatty acid derangement. |
PubMed: | Extremely decreased release of prostaglandin E2-like activity from chopped lung of ethyl linolenate-supplemented rats. |
PubMed: | Urinary prostaglandin E2 and vasopressin excretion in essential fatty acid-deficient rats: effect of linolenic acid supplementation. |
PubMed: | Activation of catalase and other enzymes by corn oil intake. |
PubMed: | Polyunsaturated fatty acids as promoters of mammary carcinogenesis induced in Sprague-Dawley rats by 7,12-dimethylbenz[a]anthracene. |
PubMed: | Studies in burns, XVI: The effect of surgical trauma on metabolic heat production. |
PubMed: | Growth and liver lipids of casein-fed rats incubated in the presence of glucose and lipid. |
PubMed: | Studies in burns: XV. Use of a topical lipid in treating human burns. |
PubMed: | Studies in burns: XIV, Heling in burn wounds treated with Ethyl Linoleate alone or in combination with selected topical antibacterial agents. |
PubMed: | Studies in burns. XIII. Effects of a topical lipid on burned subjects and their wounds. |
PubMed: | In situ production of a synthetic barrier dressing for burn wounds in rats. |
PubMed: | Fat deficiency in rats during development of the central nervous system and susceptibility to experimental allergic encephalomyelitis. |
PubMed: | Studies in burns. XI. Ethyl linoleate: the water-holding lipid of skin. B. Effects on in vivo burn eschar. |
PubMed: | Studies in burns. X. Ethyl linoleate: the water-holding lipid of skin. A. The evidence. |
PubMed: | Effects of antoxidants on the long-term utility of ethyl linoleate as a water-holding lipid for topical use postburn. |
PubMed: | [Influence of dietary ethyl linoleate, ethyl linolenate and choline upon fatty acid metabolism of rat heart (author's transl)]. |
PubMed: | Ethyl linoleate, atherosclerosis and longevity. |
PubMed: | Reduction of atherogenicity of natural fats by small additions of ethyl linoleate in the diet of the rat. |
PubMed: | Effects of ethyl linoleate on chronic liver diseases with special reference to lipid metabolism. |
PubMed: | [Fatty acid composition of serum lipoprotein-lipids in normal and arteriosclerotic subjects. I. Fatty acid composition of lipoprotein in normal and arteriosclerotic subjects. II. Effects of ethyl linoleate on the fatty acid composition of serum lipoprotein]. |
PubMed: | Ethyl linoleate as an antiatherogenic agent. An experimental study in rabbits. |
PubMed: | Effect of ethyl linoleate, ethyl linolenate and ethyl esters of highly unsaturated fatty acids on essential fatty acid deficiency in rainbow trout. |
PubMed: | Effects of ethyl-linoleate on the atheromatous changes caused by high cholesterol diet in the rabbit. |
PubMed: | Ethyl linoleate in the management of intractable angina. |
PubMed: | ETHYL LINOLEATE IN EXPERIMENTAL ATHEROGENESIS. |
PubMed: | The influence of ethyl linoleate and ethyl linolenate on polyenoic fatty acids and cholesterol in tissues of chicks. |
PubMed: | Xanthomatous biliary cirrhosis treated with ethyl linoleate. |
PubMed: | A case of xanthomatous biliary cirrhosis treated with ethyl linoleate. |
PubMed: | The role of fat in the diet of rats. 11. Influence of a small amount of ethyl linoleate on degeneration of spermatogenic tissue caused by hydrogenated arachis oil as the sole dietary fat. |
PubMed: | The effect of fat level of the diet on general nutrition. XI. The protective effect of varying levels of ethyl linoleate against multiple sublethal doses of x-irradiation in the rat. |
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