alpha-bisabolol
(2R)-6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hept-5-en-2-ol
 
Notes:
monocyclic sesquiterpene alcohol with strong bacteriocidal effects, especilly against m. tuberc.; isolated from seed plant populus tacamacaha.
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
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      Product(s):
      Alpha Bisabolol
       
  • BOC Sciences
    • BOC Sciences
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      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      515-69-5 alpha-Bisabolol >75.0%(GC)
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      Products List: View
      Product(s):
      MP-002067 ALFA-BISABOLOL
       
  • Glentham Life Sciences
  • Moellhausen
  • Pell Wall Perfumes
    • Pell Wall Perfumes
      Hand-made fragrances
      Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock.
      Pell Wall was founded by perfumer Chris Bartlett to provide exclusive hand-made fragrances to a select few people who love them. All our products are created using fine quality ingredients, many of which we also offer for sale to other perfumers and enthusiasts. Pell Wall make fragrances for men, for women and for the home.
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      Product(s):
      Bisabolol
      Arctander describes it as "Sweet and very mild, delicately floral odor.” and goes on to point out that at that time “Although not regularly available or generally offered as a synthetic material yet, this sesquiterpene alcohol should soon become known and possibly find use as a blender / fixative of very versatile use. Its acceptability and popularity will, of course, largely depend upon the cost level. But with the enormous drop in the cost of synthetic Nerolidol over a period of less than 10 years to a level where this alcohol can be used in almost any type of fragrance, there may be good hope that Bisabolol can achieve a similar level of popuIarity."
       
       
  • Penta International
  • Symrise
    • Symrise AG
      Always Insiring More
      Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.
      We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success.
      US Email: Life Essentials
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      Product(s):
      600115 Dragosantol® 100 Life Essentials - Actives
      Dragosantol® 100 is a monocyclic unsaturated sesquiterpene alcohol, alpha-bisabolol. Dragosantol® 100 contains at least 95 % of alpha-bisabolol. The content of farnesol is less than 0.1 % / 1000 ppm. Alpha-bisabolol is quite close to a known ingredient of chamomile. Like chamomile it is known for its soothing effect and widely used in skin care cosmetics. Dragosantol® 100 is an ideal ingredient for stressed and sensitive skin cosmetics
       
      172585 Dragosantol® Bisabolol and Farnesol
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      B2119 (±)-a-Bisabolol >80.0%(GC)
       
  • The Lermond Company
    • The Lermond Company
      Your Sourcing Resource
      The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.
      The Lermond Company is a women-owned distributor of raw materials primarily servicing the flavor and fragrance industry. For three generations, members of the Lermond family have been integral sourcing partners for the North American flavor and fragrance industry. We supply high quality essential oils, aroma chemicals, absolutes, concretes, resinoids and floral waters from around the world to the global industry.
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      Product(s):
      13699 BISABOLOL
       
Synonyms   Articles   Notes   Search
CAS Number: 515-69-5Picture of molecule3D/inchi
Other(deleted CASRN): 21090-60-8
ECHA EINECS - REACH Pre-Reg: 208-205-9
FDA UNII: 36HQN158VC
Nikkaji Web: J144.007A
Beilstein Number: 5733954
MDL: MFCD00129082
CoE Number: 10178
XlogP3-AA: 3.80 (est)
Molecular Weight: 222.37142000
Formula: C15 H26 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome, Edge or firefox)
EFSA/JECFA Comments: Register name to be changed to (l)-alpha-Bisabolol. Secondary components (no amount given): (d)-alpha-Bisabolol (CAS No. 23178-88-3), (l)-epi-alpha-Bisabolol (CAS No.78148-59-1), (d)-epi-alpha-Bisabolol (CAS No. 76738-75-5).
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
DG SANTE Food Flavourings: 02.129  alpha-bisabolol
FEMA Number: 4666 alpha-bisabolol
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):515-69-5 ; ALPHA-BISABOLOL
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless clear viscous liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 314.00 to  315.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.000040 mmHg @ 25.00 °C. (est)
Flash Point: 275.00 °F. TCC ( 135.00 °C. )
logP (o/w): 5.070 (est)
Soluble in:
 alcohol
 water, 1.688 mg/L @ 25 °C (est)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: floral
 
Odor Strength: low
 
 floral  peppery  balsamic  clean  
Odor Description:
at 100.00 %. 
mild floral peppery balsamic clean
 
Odor and/or flavor descriptions from others (if found).
 
Symrise
Dragosantol® 100 Life Essentials - Actives
Odor Description: characteristc
Dragosantol® 100 is a monocyclic unsaturated sesquiterpene alcohol, alpha-bisabolol. Dragosantol® 100 contains at least 95 % of alpha-bisabolol. The content of farnesol is less than 0.1 % / 1000 ppm. Alpha-bisabolol is quite close to a known ingredient of chamomile. Like chamomile it is known for its soothing effect and widely used in skin care cosmetics. Dragosantol® 100 is an ideal ingredient for stressed and sensitive skin cosmetics
 
Pell Wall Perfumes
Bisabolol
Odor Description: Floral, sweet, balsamic. Mild. Fixative
Arctander describes it as "Sweet and very mild, delicately floral odor.” and goes on to point out that at that time “Although not regularly available or generally offered as a synthetic material yet, this sesquiterpene alcohol should soon become known and possibly find use as a blender / fixative of very versatile use. Its acceptability and popularity will, of course, largely depend upon the cost level. But with the enormous drop in the cost of synthetic Nerolidol over a period of less than 10 years to a level where this alcohol can be used in almost any type of fragrance, there may be good hope that Bisabolol can achieve a similar level of popuIarity."
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: fragrance
skin conditioning
soothing agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Augustus Oils
Alpha Bisabolol
Services
BOC Sciences
For experimental / research use only.
alpha-Bisabolol >75.0%(GC)
ECSA Chemicals
ALFA-BISABOLOL
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Ernesto Ventós
BISABOLOL ALPHA NATURAL
George Uhe Company
a-Bisabolol Natural
Glentham Life Sciences
alpha-Bisabolol
HallStar
RTD ALPHA-BISABOLOL NATURAL
Odor: characteristic
Use: Natural alpha-Bisabolol, also known as Levomenol, may be obtained from the direct distillation of the oil from the tropical shrub candeia. This shrub, Linnean name Vanillosmopsis erythropappa, which is of the Asteraceae family, grows in the southeast and midwest regions of Brazil. This tree yields a white, hard, resinous wood and its leaves, flowers and oil have medicinal properties. Natural alpha-Bisabolol is also a major constituent of German Chamomile [Chamomilla Recutita (Matricaria) Flower Oil], which has been used in the traditional medicines of Europe for hundreds of years. The essential oil of chamomile contains up to 50% 1-alpha-bisabolol. RTD Alpha-Bisabolol Natural is an optically active viscous colorless to somewhat yellow liquid with slight characteristic floral wood odor. It contains at least 95% (-)-1-alpha-bisabolol, a monocyclic unsaturated sesquiterpene alcohol. Alpha-Bisabolol, which is nontoxic and nonirritating to the skin, has been shown to possess anti-inflammatory and wound healing properties, as well as antimycotic and antibacterial effects. Specifically, it is a potent inhibitor of fungi, Candida albicans and gram-positive bacteria. RTD Alpha-Bisabolol Natural is suitable for use in skin care products where the formulator wishes to take advantage of its anti-inflammatory, bactericidal and antimycotic properties, which make it a preferred active ingredient for protection of skin against stresses including cleansing, shaving, depilation, and sun exposure. When RTD Alpha-Bisabolol Natural is used at low levels (0.1 - 1.0% is recommended), it is active, safe, and skin compatible. NATURAL VS. SYNTHETIC BISABOLOL As previously noted, the essential oils of both chamomile and candeia are good botanical sources for preparing 95+% pure (-) alpha-Bisabolol. Bisabolol can also be made by chemical synthesis. The substance thus obtained, however, is only about 85% pure Bisabolol and, further, is a racemic mixture of both levorotary and dextrorotary isomers. So the synthetic product contains only about 42% of active (-) isomer. When considering the cost effectiveness of natural vs. synthetic material, remember that 1 kg natural Alpha-Bisabolol contains a minimum of 950 g active (-) Alpha-Bisabolol, while 1 kg synthetic Alpha-Bisabolol contains only about 425 g active (-) Alpha-Bisabolol. So on an “actives" basis, RTD Alpha-Bisabolol Natural is about 2.24 times more potent than synthetic material.
Kingyoung Bio Technical
Bisabolol
Lipo Chemicals
Lipo® Bisabolol
Odor: characteristic
Use: Lipo® Bisabolol is a plant-derived ingredient, extracted from Vanillosmopsis erythropappa, which reduces irritation, smoothes and soothes the skin.
Moellhausen
ALPHA BISABOLOL
Pangaea Sciences
alpha-Bisabolol Natural
Pell Wall Perfumes
Bisabolol
Odor: Floral, sweet, balsamic. Mild. Fixative
Use: Arctander describes it as "Sweet and very mild, delicately floral odor.” and goes on to point out that at that time “Although not regularly available or generally offered as a synthetic material yet, this sesquiterpene alcohol should soon become known and possibly find use as a blender / fixative of very versatile use. Its acceptability and popularity will, of course, largely depend upon the cost level. But with the enormous drop in the cost of synthetic Nerolidol over a period of less than 10 years to a level where this alcohol can be used in almost any type of fragrance, there may be good hope that Bisabolol can achieve a similar level of popuIarity."
Penta International
ALPHA-BISABOLOL NATURAL EX-WORMWOOD OIL
Penta International
ALPHA-BISABOLOL NATURAL
Penta International
ALPHA-BISABOLOL
Phoenix Aromas & Essential Oils
Alpha-Bisabolol Natural
R C Treatt & Co Ltd
alpha-Bisabolol ex Lemon Natural
Odor: Lemon, citrus, floral, tangy, fresh and clean
Santa Cruz Biotechnology
For experimental / research use only.
a-Bisabolol
Symrise
Dragosantol® 100
Life Essentials - Actives
Odor: characteristc
Use: Dragosantol® 100 is a monocyclic unsaturated sesquiterpene alcohol, alpha-bisabolol. Dragosantol® 100 contains at least 95 % of alpha-bisabolol. The content of farnesol is less than 0.1 % / 1000 ppm. Alpha-bisabolol is quite close to a known ingredient of chamomile. Like chamomile it is known for its soothing effect and widely used in skin care cosmetics. Dragosantol® 100 is an ideal ingredient for stressed and sensitive skin cosmetics
Symrise
Dragosantol®
Bisabolol and Farnesol
TCI AMERICA
For experimental / research use only.
(±)-a-Bisabolol >80.0%(GC)
The Lermond Company
BISABOLOL
TRI-K Industries
alpha-bisabolol
Vigon International
Dragosantol 100 (Alpha Bisabalol Synthetic - High Purity)
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  > 5000 mg/kg
International Journal of Toxicology. Vol. 18

intraperitoneal-mouse LD50  633 mg/kg
BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): HAIR: OTHER LUNGS, THORAX, OR RESPIRATION: DYSPNEA
International Journal of Toxicology. Vol. 18(Suppl

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect: Dermal sensitization and systemic toxicity
IFRA: View Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.42 %
Category 2: Products applied to the axillae
0.13 %
Category 3: Products applied to the face/body using fingertips
2.50 %
Category 4: Products related to fine fragrance
2.40 %
 Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.60 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.60 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.60 %
Category 5D: Baby Creams, baby Oils and baby talc
0.20 %
Category 6: Products with oral and lip exposure
1.40 %
 Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
3.00 %
Category 7B: Leave-on products applied to the hair with some hand contact
3.00 %
Category 8: Products with significant anogenital exposure
0.20 %
Category 9: Products with body and hand exposure, primarily rinse off
4.60 %
 Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
4.60 %
Category 10B: Household aerosol/spray products
17.00 %
 Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
0.20 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
0.20 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction
 Notes:
IFRA FLAVOR REQUIREMENTS:

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.

use level in formulae for use in cosmetics:
  0.0050 %
Dermal Systemic Exposure in Cosmetic Products:
 0.0001 mg/kg/day (IFRA, 2006)
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 27.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 5700 (μg/person/day)
Threshold of Concern:90 (μg/person/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: 4.0000020.00000
beverages(nonalcoholic): 10.0000030.00000
beverages(alcoholic): 10.0000030.00000
breakfast cereal: 10.0000030.00000
cheese: --
chewing gum: 50.00000500.00000
condiments / relishes: --
confectionery froastings: 20.00000100.00000
egg products: --
fats / oils: 10.0000050.00000
fish products: --
frozen dairy: 8.0000050.00000
fruit ices: 8.0000050.00000
gelatins / puddings: 8.0000050.00000
granulated sugar: --
gravies: --
hard candy: 20.00000100.00000
imitation dairy: 10.0000030.00000
instant coffee / tea: 10.0000050.00000
jams / jellies: --
meat products: --
milk products: 10.0000030.00000
nut products: --
other grains: --
poultry: --
processed fruits: 10.0000030.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 20.00000100.00000
snack foods: --
soft candy: 20.00000100.00000
soups: 8.0000050.00000
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 10.0000050.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 10.0000050.00000
Edible ices, including sherbet and sorbet (03.0): 8.0000050.00000
Processed fruit (04.1): 10.0000030.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 20.00000100.00000
Chewing gum (05.0): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 10.0000030.00000
Bakery wares (07.0): 4.0000020.00000
Meat and meat products, including poultry and game (08.0): --
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): --
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 20.00000100.00000
Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 10.0000030.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000030.00000
Ready-to-eat savouries (15.0): --
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 10.00000500.00000
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Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on Flavouring Group Evaluation 18, Revision 2 (FGE.18Rev2): Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters from chemical groups 6 and 8.
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 18, Revision 3 (FGE.18Rev3): Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters from chemical groups 6 and 8.
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 515-69-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 1549992
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 (2R)-6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hept-5-en-2-ol
Chemidplus: 0000515695
RTECS: MJ9685000 for cas# 515-69-5
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References:
 (2R)-6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hept-5-en-2-ol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 515-69-5
Pubchem (cid): 1549992
Pubchem (sid): 134975910
Flavornet: 515-69-5
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEMBL: View
HMDB (The Human Metabolome Database): Search
FooDB: FDB021850
Export Tariff Code: 2906.19.5000
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 tagete oil rwanda 
(R)-limonene-10-olFL/FR
aldehydic
 adoxal (Givaudan)FL/FR
 citronellyl oxyacetaldehydeFL/FR
9-decenalFL/FR
 mandarine undecenalFL/FR
 muguet undecadienalFR
(Z)-8-undecenalFR
animal
isobutyl quinolineFR
balsamic
 benzyl cinnamateFL/FR
 benzyl salicylateFL/FR
 cinnamyl cinnamateFL/FR
 cinnamyl formateFL/FR
alpha-methyl cinnamyl alcoholFR
 nopolFL/FR
 tolu balsam oilFL/FR
citrus
 citronellyl nitrileFR
 grapefruit pentanolFR
10-undecen-1-olFL/FR
ethereal
 ethyl 4-pentenoateFL/FR
fatty
2-decenalFL/FR
(E)-2-octenalFL/FR
fir needle
 abies amabilis oil canadaFR
floral
 amyl benzoateFL/FR
 bursera graveolens wood oilFL/FR
alpha-butyl cinnamaldehydeFL/FR
 cananga oilFL/FR
 cananga oil chinaFL/FR
 citronellyl acetateFL/FR
 citronellyl acetoneFL/FR
 citronellyl propionateFL/FR
 citrus propanolFR
 cumin carbinolFR
 cyclohexyl ethyl alcoholFL/FR
 cyclohexyl salicylateFR
 dihydrogeranyl linaloolFR
 dihydrorose oxideFR
 dimethyl benzyl carbinolFL/FR
 dimethyl benzyl carbinyl butyrateFL/FR
6,8-dimethyl-2-nonanolFR
2,4-dimethyl-3-cyclohexene-1-methanolFR
 floral butanalFR
 floral undecenoneFR
 geranium oil africaFL/FR
 geranium oil bourbonFL/FR
 geranium oil egyptFL/FR
 geranyl acetoneFL/FR
 geranyl isobutyrateFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
 hexyl 2-furoateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
beta-ionolFL/FR
 jasmin cyclopentanolFR
 jonquil absoluteFR
 lily flower absoluteFR
 methyl citronellateFL/FR
 mimosa absolute franceFL/FR
 neroli oil bigardeFL/FR
 nerolidolFL/FR
 neryl formateFL/FR
3-nonanon-1-yl acetateFL/FR
 orange leaf absoluteFL/FR
 papaya isobutyrateFL/FR
2-pentyl cyclopentanoneFR
 phenethyl hexanoateFL/FR
 phenethyl salicylateFL/FR
2-phenyl propionaldehyde ethylene glycol acetalFR
1-phenyl propyl alcoholFL/FR
3-phenyl propyl propionateFL/FR
4-phenyl-3-buten-2-olFL/FR
(Z,E)-phytolFL/FR
isophytolFL/FR
 reseda absoluteFR
 rose butanoateFL/FR
 rose pyranFR
 sweet pea absoluteFR
 verdyl acetateFR
fruity
 benzyl propionateFL/FR
 bisaboleneFL/FR
 cyclohexyl crotonateFR
 ethyl methyl-para-tolyl glycidateFL/FR
 methyl heptanoateFL/FR
 tropical indeneFR
green
isobutyl heptanoateFL/FR
isobutyl methyl ketoneFL/FR
2-sec-butyl thiazoleFL/FR
 heptanal (aldehyde C-7)FL/FR
1-heptanolFL/FR
 heptyl formateFL/FR
(E)-4-hexen-1-ol 
(Z)-4-hexen-1-olFL/FR
(Z)-3-hexen-1-yl benzoateFL/FR
3-hexenyl 2-methyl butyrateFL/FR
 hexyl hexanoateFL/FR
 ivy dioxolaneFR
english ivy leaf absoluteFR
para-methyl hydratropaldehydeFL/FR
 methyl octine carbonateFL/FR
 octanal dimethyl acetalFL/FR
 seaweed absolute (fucus vesiculosus et serratus)FL/FR
herbal
6-acetoxydihydrotheaspiraneFL/FR
alpha-amyl cinnamyl formateFL/FR
 anethum graveolens herb oilFL/FR
 anthemis nobilis flower oil romanFL/FR
sweet basil absoluteFL/FR
 bursera graveolens wood 
(+)-alpha-campholenic aldehydeFL/FR
 cardamom liquid resinFR
 dill weed oil cubaFL/FR
 dill weed oil reunionFL/FR
 dimethyl benzyl carbinyl formateFL/FR
 eucalyptus citriodora oilFR
 glyceryl tribenzoateCS
cis-herbal cyclohexaneFR
 herbal dioxaneFR
 herbal heptaneFR
 hop absoluteFL/FR
 hop oilFL/FR
 linalyl formateFL/FR
 linalyl octanoateFL/FR
 marigold oil mexicoFL/FR
 melaleuca leucadendron var. cajuputi leaf oilFL/FR
(E)-6-methyl-3-hepten-2-oneFL/FR
 mistletoe absolute 
 nonisyl formateFR
1-octen-3-yl acetateFL/FR
 origanum oilFL/FR
 origanum oil greeceFL/FR
 perillaldehydeFL/FR
 tagete oil CO2 extractFL/FR
 tagete oil south africaFL/FR
 theaspiraneFL/FR
 tricyclodecyl acetateFR
 viridiflorolFL/FR
 wormwood oil americaFL/FR
honey
 methyl hydrocinnamateFL/FR
minty
(-)-isopulegolFL/FR
pine
 dipentene terpene hydrocarbon byproductsFR
spicy
 amyl isoeugenolFR
isobutyl angelateFL/FR
 cubeb oil CO2 extract (piper cubeba)FL/FR
(-)-cubenolFL/FR
 cuminaldehydeFL/FR
isocyclogeraniol (IFF)FR
terpenic
laevo-limoneneFL/FR
waxy
3-decanoneFL/FR
 ethyl laurateFL/FR
 hexadecanolFL/FR
woody
 abies grandis oil canadaFR
isolongifolene epoxideFR
 methyl vetivateFR
 sandal cyclopropaneFL/FR
(R)-sandal hexanolFR
alpha-thujene 
 verdoxanFR
 
For Flavor
 
No flavor group found for these
6-acetoxydihydrotheaspiraneFL/FR
 amyl benzoateFL/FR
alpha-amyl cinnamyl formateFL/FR
 bursera graveolens wood 
 bursera graveolens wood oilFL/FR
isobutyl heptanoateFL/FR
4-butyl thiazoleFL
2-sec-butyl thiazoleFL/FR
 citronellyl acetoneFL/FR
3-decanoneFL/FR
9-decenalFL/FR
 dimethyl benzyl carbinyl formateFL/FR
 ethyl 4-pentenoateFL/FR
 fig leaf absoluteFL
(E,E)-2,4-hexadien-1-olFL
(R)-limonene-10-olFL/FR
 linalyl formateFL/FR
 melaleuca leucadendron var. cajuputi leaf oilFL/FR
 methyl hydrocinnamateFL/FR
(E)-6-methyl-3-hepten-2-oneFL/FR
 mistletoe absolute 
 nopolFL/FR
3-phenyl propyl propionateFL/FR
2-propyl thiazoleFL
 seaweed absolute (fucus vesiculosus et serratus)FL/FR
 tagete oil rwanda 
alpha-thujene 
10-undecen-1-olFL/FR
 viridiflorolFL/FR
alpha-butyl cinnamaldehydeFL/FR
amber
 sandal cyclopropaneFL/FR
balsamic
 benzyl salicylateFL/FR
1-phenyl propyl alcoholFL/FR
(Z,E)-phytolFL/FR
 tolu balsam oilFL/FR
citrus
 bisaboleneFL/FR
 citronellyl oxyacetaldehydeFL/FR
cooling
 theaspiraneFL/FR
fatty
2-decenalFL/FR
 heptyl formateFL/FR
(Z)-3-hexen-1-yl benzoateFL/FR
(E)-2-octenalFL/FR
floral
 cananga oilFL/FR
 cananga oil chinaFL/FR
 citronellyl acetateFL/FR
 citronellyl propionateFL/FR
 dimethyl benzyl carbinyl butyrateFL/FR
 geranium oil africaFL/FR
 geranium oil bourbonFL/FR
 geranium oil egyptFL/FR
 geranyl acetoneFL/FR
 geranyl isobutyrateFL/FR
beta-ionolFL/FR
pseudoiononeFL
 methyl citronellateFL/FR
 neroli oil bigardeFL/FR
 orange leaf absoluteFL/FR
fruity
 benzyl propionateFL/FR
 ethyl methyl-para-tolyl glycidateFL/FR
 hexyl hexanoateFL/FR
 linalyl octanoateFL/FR
 methyl heptanoateFL/FR
 neryl formateFL/FR
3-nonanon-1-yl acetateFL/FR
 rose butanoateFL/FR
 tagete oil CO2 extractFL/FR
 tagete oil south africaFL/FR
green
isobutyl angelateFL/FR
isobutyl methyl ketoneFL/FR
(+)-alpha-campholenic aldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
 heptanal (aldehyde C-7)FL/FR
(E)-4-hexen-1-ol 
(Z)-4-hexen-1-olFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
3-hexenyl 2-methyl butyrateFL/FR
 hexyl 2-furoateFL/FR
para-methyl hydratropaldehydeFL/FR
 methyl octine carbonateFL/FR
 nerolidolFL/FR
 octanal dimethyl acetalFL/FR
1-octen-3-yl acetateFL/FR
 papaya isobutyrateFL/FR
herbal
 anethum graveolens herb oilFL/FR
 anthemis nobilis flower oil romanFL/FR
sweet basil absoluteFL/FR
 dill weed oil cubaFL/FR
 dill weed oil reunionFL/FR
 hop absoluteFL/FR
 hop oilFL/FR
 marigold oil mexicoFL/FR
 origanum oilFL/FR
 origanum oil greeceFL/FR
 wormwood oil americaFL/FR
medicinal
 dimethyl benzyl carbinolFL/FR
 phenethyl salicylateFL/FR
minty
(-)-isopulegolFL/FR
oily
isophytolFL/FR
solvent
1-heptanolFL/FR
spicy
 benzyl cinnamateFL/FR
 cinnamyl cinnamateFL/FR
 cinnamyl formateFL/FR
 cubeb oil CO2 extract (piper cubeba)FL/FR
(-)-cubenolFL/FR
 cuminaldehydeFL/FR
 perillaldehydeFL/FR
terpenic
laevo-limoneneFL/FR
waxy
 adoxal (Givaudan)FL/FR
 ethyl laurateFL/FR
 hexadecanolFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 mandarine undecenalFL/FR
 mimosa absolute franceFL/FR
 phenethyl hexanoateFL/FR
4-phenyl-3-buten-2-olFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 bergamotFR
 carrotFL
 floralFR
 gingerFR
 grapefruitFR
 guavaFR
 lavenderFR
 lemonFR
 limeFR
 orangeFR
 pepperFR
 sandalwoodFR
 ylang ylangFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 abies holophylla
PbMd  Search Trop  Picture
 artemisia campestris spp. glutinosa flower oil italy @ 7.00%
Data  GC  Search Trop  Picture
 artemisia variabilis flower oil italy @ 1.00%
Data  GC  Search Trop  Picture
 basil oil
Search Trop  Picture
 bergamot oil @ 0.007-0.030%
Data  GC  Search Trop  Picture
 bergamot oil @ trace%
Data  GC  Search Trop  Picture
 camomile flowers
Search  PMC Picture
 carrot seed oil @ 0.21%
Data  GC  Search Trop  Picture
 cascarilla bark oil @ trace%
Data  GC  Search Trop  Picture
 cedarwood oil atlanta @ 0.30%
Data  GC  Search Trop  Picture
 cedarwood oil china @ 0.80%
Data  GC  Search Trop  Picture
 cedarwood oil texas @ 0.40%
Data  GC  Search Trop  Picture
 cedarwood oil virginia @ 0.60%
Data  GC  Search Trop  Picture
 chamomile flower oil germany @ 0.51%
Data  GC  Search Trop  Picture
 chamomile sweet false chamomile flower
Search Trop  Picture
 corn oil
Search Trop  Picture
 corn seed oil
Search Trop  Picture
 croton cajucara benth. leaf oil brazil @ 0.40%
Data  GC  Search Trop  Picture
 cubeb oil @ 0.37%
Data  GC  Search Trop  Picture
 fleabane oil @ 0.40%
Data  GC  Search Trop  Picture
 ginger root oil CO2 extract australia @ 0.14%
Data  GC  Search Trop  Picture
 guava fruit oil reunion @ 0.70%
Data  GC  Search Trop  Picture
 guava leaf oil cuba @ 3.20%
Data  GC  Search Trop  Picture
 juniper branch oil @ 0.20%
Data  GC  Search Trop  Picture
 lavender oil CO2 extract france @ 2.09%
Data  GC  Search Trop  Picture
 lavender oil spike spain @ 0.23%
Data  GC  Search Trop  Picture
 lemon oil california @ 0.04%
Data  GC  Search Trop  Picture
 lime oil distilled mexico @ 0.06%
Data  GC  Search Trop  Picture
 lime oil distilled peru @ 0.06%
Data  GC  Search Trop  Picture
 lime oil expressed florida @ trace%
Data  GC  Search Trop  Picture
 nepeta betonicifolia c.a. meyer oil turkey @ 0.20%
Data  GC  Search Trop  Picture
 orange oil
Search Trop  Picture
 phoebe oil brazil @ 3.33%
Data  GC  Search Trop  Picture
 pine needle oil dwarf @ trace%
Data  GC  Search Trop  Picture
 plinia cerrocampanensis barrie
PbMd  Search Trop  Picture
 prangos uechtritzii boiss. et hausskn. fruit oil turkey @ 2.10%
Data  GC  Search Trop  Picture
 pteronia oil @ 0.70%
Data  GC  Search Trop  Picture
 rosemary oil france @ 0.00-0.27%
Data  GC  Search Trop  Picture
 sandalwood oil east indian @ 0.26%
Data  GC  Search Trop  Picture
 tansy oil marocco @ 0.60%
Data  GC  Search Trop  Picture
 wormwood oil italy @ trace%
Data  GC  Search Trop  Picture
 wormwood oil poland @ 0.74%
Data  GC  Search Trop  Picture
 yarrow oil greece @ 0.10%
Data  GC  Search Trop  Picture
 ylang ylang oil @ 0.07%
Data  GC  Search Trop  Picture
 ylang ylang oil CO2 extract @ 0.61%
Data  GC  Search Trop  Picture
 zingiber officinale root oil china @ 0.78%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 bisabola-1,12-dien-8-ol
 bisabolol
dextro,laevo-alpha-bisabolol
DL-alpha-bisabolol
 bisabolol alpha racemic synthetic
alpha-bisabolol ex lemon natural
alpha-bisabolol nat.
alpha-bisabolol natural
alpha-bisabolol rac.
3-cyclohexene-1-methanol, a,4-dimethyl-a-(4-methyl-3-penten-1-yl)-, (aR,1R)-
3-cyclohexene-1-methanol, a,4-dimethyl-a-(4-methyl-3-pentenyl)-, (aR,1R)-rel-
(R*,R*)-6-dethyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
(R*,R*)-(1)-alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl) cyclohex-3-ene-1-methanol
(R*,R*)-alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl) cyclohex-3-ene-1-methanol
alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
 dragosantol 100 (Symrise)
(2R)-6-methyl-2-((1R)-4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
(R)-6-methyl-2-((R)-4-methyl-cyclohex-3-enyl)-hept-5-en-2-ol
(R)-6-methyl-2-((R)-4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
(2R)-6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hept-5-en-2-ol
(2R)-6-methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol
rel-(2R)-6-methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol
1-methyl-4-(1-hydroxy-1,5,5-trimethyl-4-pentenyl) cyclohex-1-ene
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: The essential oil of Populus balsamifera buds: its chemical composition and cytotoxic activity.
PubMed: Antinociceptive and anti-edematous activities of the essential oils of two Balkan endemic Laserpitium species.
PubMed: Antitumor activity of the protein and small molecule component fractions from Agrocybe aegerita through enhancement of cytokine production.
PubMed: Chemical composition, antibacterial, antifungal and antioxidant activities of Algerian Eryngium tricuspidatum L. essential oil.
PubMed: Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.
PubMed: Antimicrobial activity of essential oils and five terpenoid compounds against Campylobacter jejuni in pure and mixed culture experiments.
PubMed: Antihyperalgesic and antiedematous activities of bisabolol-oxides-rich matricaria oil in a rat model of inflammation.
PubMed: Chemical composition and biological activities of essential oils of Eremanthus erythropappus (DC) McLeisch (Asteraceae).
PubMed: In Vitro Antileishmanial Activity of Essential Oil of Vanillosmopsis arborea (Asteraceae) Baker.
PubMed: Distinct mechanisms of relaxation to bioactive components from chamomile species in porcine isolated blood vessels.
PubMed: Chemical composition and biological activity of the essential oil of Amomum biflorum.
PubMed: Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.
PubMed: VOC contamination in hospital, from stationary sampling of a large panel of compounds, in view of healthcare workers and patients exposure assessment.
PubMed: Genome mining reveals two novel bacterial sesquiterpene cyclases: (-)-germacradien-4-ol and (-)-epi-α-bisabolol synthases from Streptomyces citricolor.
PubMed: Chemical composition and antiphytoviral activity of essential oil of Micromeria graeca.
PubMed: α-bisabolol is an effective proapoptotic agent against BCR-ABL(+) cells in synergism with Imatinib and Nilotinib.
PubMed: An untargeted metabolomic approach in the chemotaxonomic assessment of two Salvia species as a potential source of α-bisabolol.
PubMed: The antimicrobial activity of alpha-bisabolol and tea tree oil against Solobacterium moorei, a Gram-positive bacterium associated with halitosis.
PubMed: Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis.
PubMed: Attenuation of visceral nociception by α-bisabolol in mice: investigation of mechanisms.
PubMed: Bioactivity of the essential oil of an argentine collection of Acanthospermum hispidum (Asteraceae).
PubMed: In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil.
PubMed: Composition of the essential oils and antibacterial activities of Hymenocrater yazdianus, Stachys obtusicrena and Nepeta asterotricha three Labiatae herbs growing wild in Iran.
PubMed: Fast quality assessment of German chamomile (Matricaria chamomilla L.) by headspace solid-phase microextraction: influence of flower development stage.
PubMed: Enhanced topical delivery of small hydrophilic or lipophilic active agents and epidermal growth factor by fractional radiofrequency microporation.
PubMed: Activity of Matricaria chamomilla essential oil against anisakiasis.
PubMed: STAT-3 inhibitory bisabolanes from Carthamus glaucus.
PubMed: Control of Tetranychus urticae Koch by extracts of three essential oils of chamomile, marjoram and Eucalyptus.
PubMed: In-vitro characterization of the pharmacological effects induced by (-)-α-bisabolol in rat smooth muscle preparations.
PubMed: Chemical and allelopathic analyses of essential oils of Prangos pabularia Lindl. from Iran.
PubMed: Psychopharmacological profile of Chamomile (Matricaria recutita L.) essential oil in mice.
PubMed: Disulphides in the volatile oil of Ferula behboudiana Rech. f. & Esfand.
PubMed: Enhancement and mechanism of transdermal absorption of terpene-induced propranolol hydrochloride.
PubMed: (-)-α-Bisabolol-induced gastroprotection is associated with reduction in lipid peroxidation, superoxide dismutase activity and neutrophil migration.
PubMed: Antitumor effects of α-bisabolol against pancreatic cancer.
PubMed: Anti-nociceptive and anti-inflammatory activities of (-)-α-bisabolol in rodents.
PubMed: Composition and antimicrobial activity of the essential oil of Heracleum thomsonii (Clarke) from the cold desert of the western Himalayas.
PubMed: [Analysis of the chemical constituents of essential oil from Anaphalis aureopunctata by GC-MS].
PubMed: A myristicin-rich essential oil from Daucus sahariensis growing in Algeria.
PubMed: Essential oil from aerial parts of of Betonica grandiflora Willd. from Iran.
PubMed: Inhibitory effects of (-)-α-bisabolol on LPS-induced inflammatory response in RAW264.7 macrophages.
PubMed: Composition and antifungal activity of the essential oil from the rhizome and roots of Ferula hermonis.
PubMed: Evaluation of thermal-oxidative stability and antiglioma activity of Zanthoxylum tingoassuiba essential oil entrapped into multi- and unilamellar liposomes.
PubMed: Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells.
PubMed: Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.
PubMed: Persistency assessment and aerobic biodegradation of selected cyclic sesquiterpenes present in essential oils.
PubMed: Hypotensive activity of terpenes found in essential oils.
PubMed: Application of a multidimensional gas chromatography system with simultaneous mass spectrometric and flame ionization detection to the analysis of sandalwood oil.
PubMed: Antiplasmodial volatile extracts from Cleistopholis patens Engler & Diels and Uvariastrum pierreanum Engl. (Engl. & Diels) (Annonaceae) growing in Cameroon.
PubMed: (-)-α-Bisabolol attenuates visceral nociception and inflammation in mice.
PubMed: Composition of volatile organic compounds in flowers of Astragalus sahendi.
PubMed: Chemical composition and antibacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum.
PubMed: Whitening effect of alpha-bisabolol in Asian women subjects.
PubMed: In vivo effect of alpha-bisabolol, a nontoxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice.
PubMed: Variability of the essential oil content and composition of chamomile (Matricaria recutita L.) affected by weather conditions.
PubMed: Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines.
PubMed: Volatile compounds of flowers and leaves of Sideritis italica (Miller) Greuter et Burdet (Lamiaceae), a plant used as mountain tea.
PubMed: Essential-oil composition, antileishmanial, and toxicity study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia.
PubMed: Effect of Matricaria chamomilla L. flower essential oil on the growth and ultrastructure of Aspergillus niger van Tieghem.
PubMed: Differentiating and apoptotic dose-dependent effects in (-)-alpha-bisabolol-treated human endothelial cells.
PubMed: alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
PubMed: Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity.
PubMed: Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate.
PubMed: Evaluation of the sesquiterpene (-)-alpha-bisabolol as a novel peripheral nervous blocker.
PubMed: Bisabolol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide, and KATP+ channels.
PubMed: Composition and biological activity of the essential oil from leaves of Plinia cerrocampanensis, a new source of alpha-bisabolol.
PubMed: Content and composition of the essential oil of Chamomilla recutita (L.) Rauschert from some European countries.
PubMed: Essential oil from Zanthoxylum tingoassuiba loaded into multilamellar liposomes useful as antimicrobial agents.
PubMed: Gastroprotection of (-)-alpha-bisabolol on acute gastric mucosal lesions in mice: the possible involved pharmacological mechanisms.
PubMed: Chemical variation of the essential oil of Prangos uloptera DC. at different stages of growth.
PubMed: Activity of (-)alpha-bisabolol against Leishmania infantum promastigotes.
PubMed: Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis.
PubMed: Treatment of pruritus in mild-to-moderate atopic dermatitis with a topical non-steroidal agent.
PubMed: Comparative analysis of chemical compositions and antimicrobial activities of essential oils from Abies holophylla and Abies koreana activities of essential oils from Abies holophylla and Abies koreana.
PubMed: Essential oil composition of three Peperomia species from the Amazon, Brazil.
PubMed: Validation of a high-performance liquid chromatography method for the determination of (-)-alpha-bisabolol from particulate systems.
PubMed: Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry.
PubMed: Synthesis and cytotoxicity evaluation of natural alpha-bisabolol beta-D-fucopyranoside and analogues.
PubMed: Gastroprotective mechanism of Vanillosmopsis arborea bark essential oil.
PubMed: Detailed analysis of the essential oil from Cistus albidus L. by combination of GC/RI, GC/MS and 13C-NMR spectroscopy.
PubMed: Determination of radix ginseng volatile oils at different ages by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry.
PubMed: Mechanisms of depigmentation by alpha-bisabolol.
PubMed: South African Salvia species: a review of biological activities and phytochemistry.
PubMed: Fragrance material review on alpha-bisabolol.
PubMed: [Characterization of chemical components of essential oil from cupitulum of Chrysanthemum morifolium cultivated in Tongxiang city].
PubMed: Insight into the apoptosis-inducing action of alpha-bisabolol towards malignant tumor cells: involvement of lipid rafts and Bid.
PubMed: Antennal and behavioral responses of Cis boleti to fungal odor of Trametes gibbosa.
PubMed: Alpha-bisabolol: unexpected plant-derived weapon in the struggle against tumour survival?
PubMed: Chemical composition and antifungal activity of Arnica longifolia, Aster hesperius, and Chrysothamnus nauseosus essential oils.
PubMed: Synthetic organic chemistry based on small ring compounds.
PubMed: Quantitative co-occurrence of sesquiterpenes; a tool for elucidating their biosynthesis in Indian sandalwood, Santalum album.
PubMed: Environmental factors influence on chemical polymorphism of the essential oils of Lychnophora ericoides.
PubMed: Anti-irritants II: Efficacy against cumulative irritation.
PubMed: Anti-irritants I: Dose-response in acute irritation.
PubMed: [GC-MS analysis of essential oils from Radix Angelicae Pubescentis].
PubMed: The hairless guinea-pig as a model for treatment of acute irritation in humans.
PubMed: A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.).
PubMed: The hairless guinea-pig as a model for treatment of cumulative irritation in humans.
PubMed: Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus.
PubMed: Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases.
PubMed: Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes.
PubMed: The in vitro pharmacological activities and a chemical investigation of three South African Salvia species.
PubMed: Evaluation of mutagenic and antimutagenic activities of alpha-bisabolol in the Salmonella/microsome assay.
PubMed: Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate.
PubMed: Hydrophilic solutes in modified carbon dioxide extraction-prediction of the extractability using molecular dynamic simulation.
PubMed: Daucane sesquiterpenes from Ferula hermonis.
PubMed: Effect of magnesium on essential oil formation of genetically transformed and non-transformed chamomile cultures.
PubMed: Composition and antibacterial activity of essential oil of Lantana achyranthifolia Desf. (Verbenaceae).
PubMed: Determination of alpha-bisabolol in human blood by micro-HPLC-ion trap MS and head space-GC-MS methods.
PubMed: Comprehensive two-dimensional gas chromatography with flame ionization and time-of-flight mass spectrometry detection: qualitative and quantitative analysis of West Australian sandalwood oil.
PubMed: Chemical composition and insecticidal activity of essential oils from Vanillosmopsis pohlii baker against Bemisia argentifolii.
PubMed: [Investigation of chemical composition of propolis extract].
PubMed: Oxygenated bisabolane fucosides from Carthamus lanatus L.
PubMed: alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells.
PubMed: In vitro anti-inflammatory effect of Carthamus lanatus L.
PubMed: New terpenoids in cultivated and wild chamomile (in vivo and in vitro).
PubMed: Analysis by gas chromatography-mass spectrometry of the essential oil from the aerial parts of Pimpinella junoniae Ceb. & Ort., gathered in La Gomera, Canary Islands, Spain.
PubMed: Determination of the ploidy level in chamomile (Chamomilla recutita (L.) Rausch.) strains rich in alpha-bisabolol.
PubMed: The ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates.
PubMed: Phase solubility studies of pure (-)-alpha-bisabolol and camomile essential oil with beta-cyclodextrin.
PubMed: Asymmetric epoxidation of homoallylic alcohols and application in a concise total synthesis of (-)-alpha-bisabolol and (-)-8-epi-alpha-bisabolol.
PubMed: [Experimental survey of a new topical anti-oxidant based on furfuryl palmitate in the treatment of child's and baby's dermatitis with eczema: results from a multicenter clinical investigation].
PubMed: Quinoline alkaloids, coumarins and volatile constituents of Helietta longifoliata.
PubMed: (+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.
PubMed: Volatile secondary metabolite pattern of callus cultures of Chamomilla recutita.
PubMed: Anthocyanin, bisabolol and phenylammonialyase activity in cell cultures of Populus deltoides.
PubMed: Production of yarrow (Achillea millefolium L.) in Norway: essential oil content and quality.
PubMed: The cyclization of farnesyl diphosphate and nerolidyl diphosphate by a purified recombinant delta-cadinene synthase.
PubMed: Chemical variations in the essential oil of Sideritis tragoriganum.
PubMed: Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L.
PubMed: A study of the production of essential oils in chamomile hairy root cultures.
PubMed: [Study of tolerance and efficacy of cosmetic preparations with lenitive action in atopic dermatitis in children].
PubMed: (+)-4-epi-alpha-bisabolol as a major sesquiterepene constituent in the leaves of two Rosa rugosa hybrids, Martin Frobisher and Vanguard.
PubMed: Effects of some components of the essential oil of chamomile, Chamomilla recutita, on histamine release from rat mast cells.
PubMed: Effect of dissolution profile and (-)-alpha-bisabolol on the gastrotoxicity of acetylsalicylic acid.
PubMed: Determination of alpha-bisabolol and d-panthenol in cosmetic products by gas chromatography.
PubMed: Studies on the Origin of (-)-alpha-Bisabolol and Chamazulene in Chamomile Preparations; Part I. Investigations by Isotope Ratio Mass Spectrometry (IRMS).
PubMed: Winter chemical defense of Alaskan balsam poplar against snowshoe hares.
PubMed: Devil's-claw (Proboscidea louisianica), essential oil and its components : Potential allelochemical agents on cotton and wheat.
PubMed: [Absorption, distribution and metabolism of [14C]-levomenol in the skin].
PubMed: [Production of essential oils by cell-suspensions of Matricaria chamomilla in a two phase system.].
PubMed: [Pharmacological studies with compounds of chamomile. IV. Studies on toxicity of (-)-alpha-bisabolol (author's transl)].
PubMed: [Pharmacological investigations with compounds of chamomile ii. new investigations on the antiphlogistic effects of (-)-alpha-bisabolol and bisabolol oxides (author's transl)].
PubMed: [Pharmacological investigations with compounds of chamomile i. on the pharmacology of (-)-alpha-bisabolol and bisabolol oxides (review) (author's transl)].
PubMed: [Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)].
PubMed: [Ether and ester of (minus)-alpha-bisabolol and analogous mono- and sesquiterpenoids with antiphlogistic effect].
PubMed: [On the inflammation inhibitory effect of (-)-alpha-bisabolol, an essential component of chamomilla oil].
PubMed: [Synthesis of alpha-bisabolol--a spasmolytically active sequiterpenic alcohol].
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