Articles:
| None found yet. Try the PubMed Search. |
o-tolyl salicylate
Notes:
Flavouring ingredient
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 617-01-6 (2-methylphenyl) 2-hydroxybenzoate
-
-
Chemical sources Association Inc Exchange of knowledge Need This Item for Flavor? You can contact the Chemical Sources Association. Events Links Product(s):
-
| CAS Number: | 617-01-6 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 210-500-2 | |
| FDA UNII: | MXU84PJ614 | |
| Nikkaji Web: | J136.477D | |
| XlogP3: | 3.80 (est) | |
| Molecular Weight: | 228.24724000 | |
| Formula: | C14 H12 O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 907 o-tolyl salicylate |
| DG SANTE Food Flavourings: | 09.807 o-tolyl salicylate |
| FEMA Number: | 3734 o-tolyl salicylate |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 617-01-6 ; O-TOLYL SALICYLATE |
Physical Properties:
| Appearance: | colorless semi-solid to solid (est) |
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.16400 to 1.17400 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 9.686 to 9.769 |
| Refractive Index: | 1.57600 to 1.58400 @ 20.00 °C. |
| Melting Point: | 25.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 180.00 °C. @ 2.00 mm Hg |
| Boiling Point: | 378.00 to 379.00 °C. @ 760.00 mm Hg |
| Acid Value: | 1.00 max. KOH/g |
| Flash Point: | 324.00 °F. TCC ( 162.22 °C. ) |
| logP (o/w): | 3.688 (est) |
| Soluble in: | |
| alcohol | |
| water, 22.02 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| Similar Items: note | |
| allyl salicylate | |
| amyl salicylate | |
| isoamyl salicylate | |
| benzyl salicylate | |
| bornyl salicylate | |
| butyl salicylate | |
| isobutyl salicylate | |
| cinnamyl salicylate | |
| para-cresyl salicylate | |
| cyclohexyl salicylate | |
| decyl salicylate | |
| 2-ethyl hexyl salicylate | |
| ethyl salicylate | |
| heptyl salicylate | |
| (E)-2-hexen-1-yl salicylate | |
| (Z)-3-hexen-1-yl salicylate | |
| hexyl salicylate | |
| menthyl salicylate | |
| homomenthyl salicylate | |
| 2-methyl butyl salicylate | |
| methyl salicylate | |
| octyl salicylate | |
| phenethyl salicylate | |
| 3-phenyl propyl salicylate | |
| phenyl salicylate | |
| prenyl salicylate | |
| propyl salicylate | |
| isopropyl salicylate | |
Organoleptic Properties:
| Odor Type: herbal | |
| Odor Strength: | medium , recommend smelling in a 1.00 % solution or less |
| herbal eucalyptus | |
| Odor Description: at 1.00 % in dipropylene glycol. | herbal eucalyptus |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Axsyn |
| For experimental / research use only. |
| Benzoic acid,2-hydroxy-, 2-methylphenyl ester |
| BOC Sciences |
| For experimental / research use only. |
| (2-methylphenyl) 2-hydroxybenzoate |
| Parchem |
| ortho-cresyl salicylate |
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the CSA |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 [sex: M,F] 1.81 ml/kg (Sterner & Chibanguza, 1983) | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor and fragrance agents | ||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for ortho-cresyl salicylate usage levels up to: | |||
| 0.1000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 28.00 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 30.00 (μg/capita/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 13 | |||
| Click here to view publication 13 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | - | |
| beverages(nonalcoholic): | - | - | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | 100.00000 | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 15.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients. View pdf | |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf | |
| Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87. View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 61159 |
| National Institute of Allergy and Infectious Diseases: | Data |
| (2-methylphenyl) 2-hydroxybenzoate | |
| Chemidplus: | 0000617016 |
References:
| (2-methylphenyl) 2-hydroxybenzoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 617-01-6 |
| Pubchem (cid): | 61159 |
| Pubchem (sid): | 135018163 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB37667 |
| FooDB: | FDB016794 |
| Export Tariff Code: | 2918.23.0000 |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| balsam | FR | |
| herbal | FR |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| benzoic acid, 2-hydroxy-, 2-methylphenyl ester | |
| o- | cresyl salicylate |
| cresyl salicylate, o- | |
| 2- | hydroxybenzoic acid 2-methyl phenyl ester |
| 2- | hydroxybenzoic acid 2-methylphenyl ester |
| 2- | methyl phenyl 2-hydroxybenzoate |
| (2- | methyl phenyl) 2-hydroxybenzoate |
| 2- | methylphenyl 2-hydroxybenzoate |
| 2- | methylphenyl salicylate |
| (2- | methylphenyl) 2-hydroxybenzoate |
| salicylic acid o-tolyl ester | |
| salicylic acid ortho-tolyl ester | |
| salicylic acid, o-tolyl ester | |
| o- | tolyl salicylate |
| ortho- | tolyl salicylate |
| tolyl salicylate, o- |