Category: special dietary and nutritional additives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white crystalline powder (est) |
Assay: | 98.00 to 100.00 %
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Food Chemicals Codex Listed: | Yes |
Melting Point: | 185.00 to 205.00 °C. @ 760.00 mm Hg
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Boiling Point: | 445.57 °C. @ 760.00 mm Hg (est)
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Flash Point: | > 200.00 °F. TCC ( > 93.33 °C. )
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logP (o/w): | -1.576 (est) |
Soluble in: |
| propylene glycol | | water, 4.221e+004 mg/L @ 25 °C (est) | | water, 4.13E+04 mg/L @ 25 °C (exp) |
Organoleptic Properties:
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Odor Type: milky |
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Odor Strength: | none |
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| milky custard cocoa oily |
Odor Description: at 100.00 %. | very mild milky custard cocoa oily Luebke, William tgsc, (2007) |
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Flavor Type: sweet |
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| sweet |
Taste Description:
| slightly sweet |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-man TDLo 27 mg/kg/1W-I BEHAVIORAL: EUPHORIA American Journal of Psychiatry. Vol. 141, Pg. 1302, 1984.
oral-mouse LD50 21700 mg/kg Drugs in Japan Vol. 6, Pg. 228, 1982.
oral-rat LD50 7500 mg/kg Drugs in Japan Vol. 6, Pg. 228, 1982.
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | special dietary and nutritional additives |
Recommendation for laevo-glutamine usage levels up to: | | not for fragrance use.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 13.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 13 |
Click here to view publication 13 |
| average usual ppm | average maximum ppm |
baked goods: | - | 350.00000 |
beverages(nonalcoholic): | - | - |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 350.00000 |
milk products: | - | - |
nut products: | - | 350.00000 |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | 350.00000 |
snack foods: | - | - |
soft candy: | - | 350.00000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list View page or View pdf |
Safety and efficacy of l-glutamine produced using Corynebacterium glutamicum NITE BP-02524 for all animal species View page or View pdf |
EPI System: | View |
ClinicalTrials.gov: | search |
Daily Med: | search |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 56-85-9 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 5961 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 1 |
| (2S)-2,5-diamino-5-oxopentanoic acid |
Chemidplus: | 0000056859 |
RTECS: | MA2275100 for cas# 56-85-9 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
balsamic |
balsamic |
2- | acetyl furan | FL/FR |
iso | amyl cinnamate | FL/FR |
| amyl cinnamate | FL/FR |
| butyl cinnamate | FL/FR |
buttery |
| butyl butyryl lactate | FL/FR |
caramellic |
| fenugreek oleoresin | FL/FR |
chocolate |
iso | amyl phenyl acetate | FL/FR |
| chocolate pyrazine A | FL/FR |
| cocoa hexenal | FL/FR |
| cocoa oleoresin | FL/FR |
| cocoa pentenal | FL/FR |
2,5- | dimethyl pyrazine | FL/FR |
2,6- | dimethyl pyrazine | FL/FR |
2- | methoxypyrazine | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
cocoa |
2-iso | butyl-3,5-(and 3,6)-dimethyl pyrazine | FL/FR |
2- | methyl butyraldehyde | FL/FR |
delta- | nonalactone | FL/FR |
creamy |
para- | vanillic acid | FL/FR |
ethereal |
iso | propyl formate | FL/FR |
fermented |
| butyl laevo-lactate | FL/FR |
3- | methyl-1-pentanol | FL/FR |
floral |
| ethyl phenyl acetate | FL/FR |
fruity |
| butyl 2-methyl butyrate | FL/FR |
| phenyl acetaldehyde | FL/FR |
herbal |
gamma- | valerolactone | FL/FR |
musty |
| cocoa butenal | FL/FR |
3,6- | cocoa pyrazine | FL/FR |
2,6- | lutidine | FL/FR |
2- | methyl pyrazine | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
2,3,5- | trimethyl pyrazine | FL/FR |
| vinyl sulfurol | FL/FR |
roasted |
| fenugreek resinoid | FL/FR |
waxy |
| ethyl palmitate | FL/FR |
| phenethyl octanoate | FL/FR |
delta- | tetradecalactone | FL/FR |
2- | tridecanone | FL/FR |
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For Flavor |
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No flavor group found for these |
| butyl cinnamate | FL/FR |
2- | butyl thiophene | FL |
2-iso | butyl-3,5-(and 3,6)-dimethyl pyrazine | FL/FR |
2(4)-iso | butyl-4(2),6-dimethyl dihydro-4H-1,3,5-dithiazine | FL |
| chocolate pyrazine A | FL/FR |
6- | decenoic acid | FL |
4,5- | dimethyl-2-ethyl thiazole | FL |
2- | methoxypyrazine | FL/FR |
| peanut dithiazine | FL |
balsamic |
| amyl cinnamate | FL/FR |
bitter |
| methyl ethoxypyrazine | FL |
brown |
| fenugreek oleoresin | FL/FR |
buttery |
| butyl laevo-lactate | FL/FR |
cabbage |
| methyl 2-thiofuroate | FL |
caramellic |
| fenugreek resinoid | FL/FR |
chocolate |
| cocoa oleoresin | FL/FR |
| cocoa propanal | FL |
cocoa |
| butyraldehyde | FL |
| cocoa hexenal | FL/FR |
coconut |
(R)- | massoia lactone | FL |
creamy |
| butyl butyryl lactate | FL/FR |
delta- | nonalactone | FL/FR |
para- | vanillic acid | FL/FR |
fatty |
2- | tridecanone | FL/FR |
floral |
iso | amyl cinnamate | FL/FR |
iso | amyl phenyl acetate | FL/FR |
| cocoa pentenal | FL/FR |
fruity |
| butyl 2-methyl butyrate | FL/FR |
| phenethyl octanoate | FL/FR |
iso | propyl formate | FL/FR |
fusel |
2- | methyl butyraldehyde | FL/FR |
green |
| cocoa butenal | FL/FR |
2- | ethyl butyraldehyde | FL |
honey |
| ethyl phenyl acetate | FL/FR |
| phenyl acetaldehyde | FL/FR |
meaty |
2,6- | dimethyl pyrazine | FL/FR |
milky |
dextro,laevo-3-( | methyl thio) butanone | FL |
musty |
2,5- | dimethyl pyrazine | FL/FR |
2,3,5- | trimethyl pyrazine | FL/FR |
nutty |
2- | acetyl furan | FL/FR |
3,6- | cocoa pyrazine | FL/FR |
2,4- | dimethyl-5-vinyl thiazole | FL |
2,6- | lutidine | FL/FR |
2- | methyl pyrazine | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
| vinyl sulfurol | FL/FR |
tonka |
gamma- | valerolactone | FL/FR |
waxy |
| ethyl palmitate | FL/FR |
delta- | tetradecalactone | FL/FR |
whiskey |
3- | methyl-1-pentanol | FL/FR |
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Potential Uses:
| antistatic agents | |
| hair conditioning | |
| skin conditioning | |
Occurrence (nature, food, other): note
Synonyms:
| ajipure glutamine | (2S)-2- | amino-4-carbamoyl butanoic acid | (2S)-2- | amino-4-carbamoylbutanoic acid | L- | aminoglutaramic acid | L-2- | aminoglutaramic acid | 2- | aminoglutaramic acid, L- | L-2- | aminoglutaramidic acid | laevo-2- | aminoglutaramidic acid | | cebrogen | (S)-2,5- | diamino-5-oxo-pentanoic acid | (2S)-2,5- | diamino-5-oxopentanoic acid | (S)-2,5- | diamino-5-oxopentanoic acid | 2,5- | diamino-5-oxopentanoic acid, (S)- | | glutamic acid 5-amide | L- | glutamic acid 5-amide | | glutamic acid amide | L- | glutamic acid g-amide | L- | glutamic acid gamma-amide | laevo- | glutamic acid gamma-amide | L- | glutamic acid-5-amide | laevo- | glutamic acid-5-amide | L- | glutamid | L- | glutamide | laevo- | glutamide | L- | glutamin | (S)-(+)- | glutamine | L- | glutamine | L-(+)- | glutamine | laevo-(+)- | glutamine | L- | glutamine (fermented) | L- | glutamine FCC | | glutamine-S | | glutamine, L- | | levoglutamid | | levoglutamide | | levoglutamina | | miglu-P | | nutrestore | | pentanoic acid, 2,5-diamino-5-oxo-, (S)- | | stimulina |
Articles:
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