laevo-glutamine
L-glutamine
 
Notes:
a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. it is synthesized from glutamic acid and ammonia. it is the principal carrier of nitrogen in the body and is an important energy source for many cells. Widely distributed in plants, e.g. beetroot. Flavouring ingredient. Dietary supplement Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code.
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      56-85-9 L-Glutamine
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      GLUTAMINE, L-
       
  • Glentham Life Sciences
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
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      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      07-28500 L-GLUTAMINE
      07-28510 L-GLUTAMINE NATURAL
       
  • Sigma-Aldrich
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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      Product(s):
      W028 L-Glutamine
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      G0063 L-Glutamine >99.0%(T)
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
      Email: Info
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      Product(s):
      7139N L-Glutamine Nat.
       
Synonyms   Articles   Notes   Search
CAS Number: 56-85-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 200-292-1
FDA UNII: 0RH81L854J
Nikkaji Web: J9.170G
Beilstein Number: 1723797
MDL: MFCD00008044
CoE Number: 17007
XlogP3: -3.10 (est)
Molecular Weight: 130.14710000
Formula: C5 H10 N2 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: special dietary and nutritional additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 1430  L-glutamine
DG SANTE Food Flavourings: 17.007  L-glutamine
FEMA Number: 3684 L-glutamine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):56-85-9 ; L-GLUTAMINE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart D--Special Dietary and Nutritional Additives
Sec. 172.320 Amino acids.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white crystalline powder (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: Yes
Melting Point: 185.00 to  205.00 °C. @ 760.00 mm Hg
Boiling Point: 445.57 °C. @ 760.00 mm Hg (est)
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): -1.576 (est)
Soluble in:
 propylene glycol
 water, 4.221e+004 mg/L @ 25 °C (est)
 water, 4.13E+04 mg/L @ 25 °C (exp)
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Organoleptic Properties:
 
Odor Type: milky
 
Odor Strength: none
 
 milky  custard  cocoa  oily  
Odor Description:
at 100.00 %. 
very mild milky custard cocoa oily
Luebke, William tgsc, (2007)
 
 
Flavor Type: sweet
 
 sweet  
Taste Description:
slightly sweet
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antistatic agents
hair conditioning
skin conditioning
Synonyms   Articles   Notes   Search   Top
Suppliers:
AIDP
L-Glutamine (Fermented) 98.5%-101.5%
Ajinomoto USA
AjiPure™ Glutamine
AjiPure™
Flavor: characteristic
Manufactured under cGMP conditions using no materials of animal origin.
Ajinomoto USA
L-Glutamine
Flavor: characteristic
Glutamine is nutritionally classified as a nonessential amino acid. It is also considered a conditionally essential amino acid, since its requirement increases significantly in conditions of accelerated catabolism—such as metabolic stress—so that its demand cannot be met by in vivo synthesis alone.
Alfa Biotechnology
For experimental / research use only.
L-Glutamine 98%
Anhui Haibei
L-Glutamine
Atlantic Chemicals
L-Glutamine
AuNutra® Industries
L-Glutamine
BOC Sciences
For experimental / research use only.
L-Glutamine
Carbosynth
For experimental / research use only.
L-Glutamine 99%
Charkit Chemical
GLUTAMINE, L-
Dow Chemical
L-Glutamine
Foodchem International
L-Glutamine
Glentham Life Sciences
L-Glutamine, GlenCell, suitable for cell culture
Glentham Life Sciences
L-Glutamine, USP grade, non-animal origin
Glentham Life Sciences
L-Glutamine
Graham Chemical
L-Glutamine
Indis NV
For experimental / research use only.
L-Glutamine
Kerry
Hyprol™ Wheat Protein
Penta International
L-GLUTAMINE NATURAL
Penta International
L-GLUTAMINE
Prinova
L-Glutamine FCC
Santa Cruz Biotechnology
For experimental / research use only.
L-Glutamine
Sigma-Aldrich
L-Glutamine
Certified Food Grade Products
Synerzine
L-Glutamine
TCI AMERICA
For experimental / research use only.
L-Glutamine >99.0%(T)
United International
L-Glutamine Nat.
Zhong Ya Chemical
L-Glutamine
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-man TDLo  27 mg/kg/1W-I
BEHAVIORAL: EUPHORIA
American Journal of Psychiatry. Vol. 141, Pg. 1302, 1984.

oral-mouse LD50  21700 mg/kg
Drugs in Japan Vol. 6, Pg. 228, 1982.

oral-rat LD50  7500 mg/kg
Drugs in Japan Vol. 6, Pg. 228, 1982.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: special dietary and nutritional additives
Recommendation for laevo-glutamine usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 13.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 13
Click here to view publication 13
 average usual ppmaverage maximum ppm
baked goods: -350.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -350.00000
milk products: --
nut products: -350.00000
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: -350.00000
snack foods: --
soft candy: -350.00000
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list
View page or View pdf
Safety and efficacy of l-glutamine produced using Corynebacterium glutamicum NITE BP-02524 for all animal species
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 56-85-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5961
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 (2S)-2,5-diamino-5-oxopentanoic acid
Chemidplus: 0000056859
RTECS: MA2275100 for cas# 56-85-9
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References:
 (2S)-2,5-diamino-5-oxopentanoic acid
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 56-85-9
Pubchem (cid): 5961
Pubchem (sid): 134972923
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): C00064
HMDB (The Human Metabolome Database): HMDB00641
FooDB: FDB012164
YMDB (Yeast Metabolome Database): YMDB00002
Export Tariff Code: 2924.19.8000
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
For Odor
balsamic
balsamic
2-acetyl furanFL/FR
isoamyl cinnamateFL/FR
 amyl cinnamateFL/FR
 butyl cinnamateFL/FR
buttery
 butyl butyryl lactateFL/FR
caramellic
 fenugreek oleoresinFL/FR
chocolate
isoamyl phenyl acetateFL/FR
 chocolate pyrazine AFL/FR
 cocoa hexenalFL/FR
 cocoa oleoresinFL/FR
 cocoa pentenalFL/FR
2,5-dimethyl pyrazineFL/FR
2,6-dimethyl pyrazineFL/FR
2-methoxypyrazineFL/FR
2,4,5-trimethyl thiazoleFL/FR
cocoa
2-isobutyl-3,5-(and 3,6)-dimethyl pyrazineFL/FR
2-methyl butyraldehydeFL/FR
delta-nonalactoneFL/FR
creamy
para-vanillic acidFL/FR
ethereal
isopropyl formateFL/FR
fermented
 butyl laevo-lactateFL/FR
3-methyl-1-pentanolFL/FR
floral
 ethyl phenyl acetateFL/FR
fruity
 butyl 2-methyl butyrateFL/FR
 phenyl acetaldehydeFL/FR
herbal
gamma-valerolactoneFL/FR
musty
 cocoa butenalFL/FR
3,6-cocoa pyrazineFL/FR
2,6-lutidineFL/FR
2-methyl pyrazineFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,3,5-trimethyl pyrazineFL/FR
 vinyl sulfurolFL/FR
roasted
 fenugreek resinoidFL/FR
waxy
 ethyl palmitateFL/FR
 phenethyl octanoateFL/FR
delta-tetradecalactoneFL/FR
2-tridecanoneFL/FR
 
For Flavor
 
No flavor group found for these
 butyl cinnamateFL/FR
2-butyl thiopheneFL
2-isobutyl-3,5-(and 3,6)-dimethyl pyrazineFL/FR
2(4)-isobutyl-4(2),6-dimethyl dihydro-4H-1,3,5-dithiazineFL
 chocolate pyrazine AFL/FR
6-decenoic acidFL
4,5-dimethyl-2-ethyl thiazoleFL
2-methoxypyrazineFL/FR
 peanut dithiazineFL
balsamic
 amyl cinnamateFL/FR
bitter
 methyl ethoxypyrazineFL
brown
 fenugreek oleoresinFL/FR
buttery
 butyl laevo-lactateFL/FR
cabbage
 methyl 2-thiofuroateFL
caramellic
 fenugreek resinoidFL/FR
chocolate
 cocoa oleoresinFL/FR
 cocoa propanalFL
cocoa
 butyraldehydeFL
 cocoa hexenalFL/FR
coconut
(R)-massoia lactoneFL
creamy
 butyl butyryl lactateFL/FR
delta-nonalactoneFL/FR
para-vanillic acidFL/FR
fatty
2-tridecanoneFL/FR
floral
isoamyl cinnamateFL/FR
isoamyl phenyl acetateFL/FR
 cocoa pentenalFL/FR
fruity
 butyl 2-methyl butyrateFL/FR
 phenethyl octanoateFL/FR
isopropyl formateFL/FR
fusel
2-methyl butyraldehydeFL/FR
green
 cocoa butenalFL/FR
2-ethyl butyraldehydeFL
honey
 ethyl phenyl acetateFL/FR
 phenyl acetaldehydeFL/FR
meaty
2,6-dimethyl pyrazineFL/FR
milky
dextro,laevo-3-(methyl thio) butanoneFL
musty
2,5-dimethyl pyrazineFL/FR
2,3,5-trimethyl pyrazineFL/FR
nutty
2-acetyl furanFL/FR
3,6-cocoa pyrazineFL/FR
2,4-dimethyl-5-vinyl thiazoleFL
2,6-lutidineFL/FR
2-methyl pyrazineFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,4,5-trimethyl thiazoleFL/FR
 vinyl sulfurolFL/FR
tonka
gamma-valerolactoneFL/FR
waxy
 ethyl palmitateFL/FR
delta-tetradecalactoneFL/FR
whiskey
3-methyl-1-pentanolFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 antistatic agents 
 hair conditioning 
 skin conditioning 
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 apple plant
Search Trop  Picture
 carrot root
Search Trop  Picture
 celery root
Search Trop  Picture
 cherry sour cherry fruit
Search Trop  Picture
 currant black currant fruit juice
Search Trop  Picture
 date palm fruit
Search Trop  Picture
 garlic bulb
Search Trop  Picture
 leek wild leek plant
Search Trop  Picture
 onion bulb
Search Trop  Picture
 orange fruit
Search Trop  Picture
 pineapple fruit
Search Trop  Picture
 potato plant
Search Trop  Picture
 sage plant
Search Trop  Picture
 tarragon leaf
Search Trop  Picture
 tarragon root
Search Trop  Picture
 tea leaf
Search Trop  Picture
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Synonyms:
 ajipure glutamine
(2S)-2-amino-4-carbamoyl butanoic acid
(2S)-2-amino-4-carbamoylbutanoic acid
L-aminoglutaramic acid
L-2-aminoglutaramic acid
2-aminoglutaramic acid, L-
L-2-aminoglutaramidic acid
laevo-2-aminoglutaramidic acid
 cebrogen
(S)-2,5-diamino-5-oxo-pentanoic acid
(2S)-2,5-diamino-5-oxopentanoic acid
(S)-2,5-diamino-5-oxopentanoic acid
2,5-diamino-5-oxopentanoic acid, (S)-
 glutamic acid 5-amide
L-glutamic acid 5-amide
 glutamic acid amide
L-glutamic acid g-amide
L-glutamic acid gamma-amide
laevo-glutamic acid gamma-amide
L-glutamic acid-5-amide
laevo-glutamic acid-5-amide
L-glutamid
L-glutamide
laevo-glutamide
L-glutamin
(S)-(+)-glutamine
L-glutamine
L-(+)-glutamine
laevo-(+)-glutamine
L-glutamine (fermented)
L-glutamine FCC
 glutamine-S
 glutamine, L-
 levoglutamid
 levoglutamide
 levoglutamina
 miglu-P
 nutrestore
 pentanoic acid, 2,5-diamino-5-oxo-, (S)-
 stimulina
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Production and optimization of L-glutaminase enzyme from Hypocrea jecorina pure culture.
PubMed: Efficient expression and purification of recombinant glutaminase from Bacillus licheniformis (GlsA) in Escherichia coli.
PubMed: Kokumi-active glutamyl peptides in cheeses and their biogeneration by Penicillium roquefortii.
PubMed: II. Glutamine and glutamate.
PubMed: Continuous production of extracellular L-glutaminase by Ca-alginate-immobilized marine Beauveria bassiana BTMF S-10 in packed-bed reactor.
PubMed: A simultaneous assay method for L-glutamate and L-pyroglutamate contents in soy sauce using a 5-oxoprolinase (without ATP hydrolyzing activity).
PubMed: Portal hyperglutamatemia after dietary supplementation with monosodium glutamate in pigs.
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