Category: flavor enhancers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white crystalline powder (est) |
Assay: | 97.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Boiling Point: | 851.40 °C. @ 760.00 mm Hg (est)
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Flash Point: | 876.00 °F. TCC ( 468.70 °C. ) (est)
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logP (o/w): | -1.023 (est) |
Soluble in: |
| water, 1e+006 mg/L @ 25 °C (est) | | alcohol, slightly |
Insoluble in: |
| ether |
Organoleptic Properties:
Odor Description: at 100.00 %. | odorless |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Ajinomoto USA |
Ajitide™ Nucleotides
Flavor: characteristic A premium line of nucleotides with the Ajinomoto touch which unlocks the taste characteristics of foods synergy with glutamates and other flavor enhancers nucleotides have. |
BOC Sciences |
For experimental / research use only. |
Disodium 5'-inosinate
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Carbosynth |
For experimental / research use only. |
Inosine 5'-monophosphate disodium salt hydrate
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ECSA Chemicals |
IMP-INOSINE 5'-DISODIUM PHOSPHATE
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ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
Kraft Chemical |
I + G
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Penta International |
DISODIUM-5-INOSINATE
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Prinova |
Disodium Inosinate
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Santa Cruz Biotechnology |
For experimental / research use only. |
Inosine 5'-monophosphate disodium salt hydrate
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Sigma-Aldrich: Sigma |
For experimental / research use only. |
Inosine 5'-monophosphate disodium salt from muscle, Sigma Grade, 99-100%
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Sinofi Food Ingredients |
Disodium Inosinate (E631 Flavor Enhancer)
Flavor: characteristic Flavour Enhancer, Instant Noodle, Pizza, Cheese, Snack Foods, Potato Chip, Crackers, Sauces, Fast Food, Baking Food, Ice Cream, Canned Food, Meats, Poultry, Sauces, Soups, Soft Candy, Puddings, Condiments, Snack Food, Fish, Seasonings. |
TCI AMERICA |
For experimental / research use only. |
Inosine 5'-Monophosphate Disodium Salt Hydrate >98.0%(HPLC)(E)
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
R 02 - Risk of explosion by shock, friction, fire or other sources of ignition. R 23/24 - Toxic by inhalation and in contact with skin.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
intraperitoneal-rat LD50 4850 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.
oral-mouse LD50 12000 mg/kg Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966.
intravenous-mouse LD50 3300 mg/kg Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966.
intraperitoneal-mouse LD50 5400 mg/kg Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966.
intravenous-rat LD50 2730 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.
oral-rat LD50 15900 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.
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Dermal Toxicity: |
subcutaneous-mouse LD50 5480 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.
subcutaneous-rat LD50 3900 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor enhancers |
Recommendation for disodium 5'-inosinate usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 13 |
Click here to view publication 13 |
| average usual ppm | average maximum ppm |
baked goods: | - | 141.00000 |
beverages(nonalcoholic): | - | 220.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | 0.40000 |
chewing gum: | - | - |
condiments / relishes: | - | 3200.00000 |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | 2000.00000 |
fish products: | - | 10.00000 |
frozen dairy: | - | 3000.00000 |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | 660.00000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 314.00000 |
milk products: | - | 46.00000 |
nut products: | - | - |
other grains: | - | 240.00000 |
poultry: | - | 200.00000 |
processed fruits: | - | - |
processed vegetables: | - | 220.00000 |
reconstituted vegetables: | - | 50.00000 |
seasonings / flavors: | - | 1000.00000 |
snack foods: | - | 50.00000 |
soft candy: | - | 3000.00000 |
soups: | - | 660.00000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Authority (EFSA) reference(s): |
Scientific Opinion on the safety and efficacy of disodium 5'-ribonucleotides, disodium 5'-guanylate, disodium 5'-inosinate for all animal species and categories View page or View pdf |
Safety and efficacy of IMP (disodium 5'-inosinate) produced by fermentation with Corynebacterium stationis KCCM 80161 for all animal species View page or View pdf |
EPI System: | View |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 4691-65-0 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 20819 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate |
Chemidplus: | 0004691650 |
RTECS: | NM7519500 for cas# 4691-65-0 |
References:
| disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 4691-65-0 |
Pubchem (cid): | 20819 |
Pubchem (sid): | 134984663 |
Other Information:
Potential Blenders and core components note
Potential Uses:
| emollients | |
| humectants | |
| skin conditioning | |
Occurrence (nature, food, other): note
Synonyms:
| ajitide nucleotides | | disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate | | disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl phosphate | | disodium 5'-O-phosphonatoinosine | | disodium 5'-ribonucleotide | | disodium 9-(5-O-phosphonato-b-D-ribofuranosyl)-9H-purin-6-ol | | disodium inosinate | | disodium inosine 5'-monophosphate | | disodium inosine 5'-phosphate | | disodium inosine-5'-monophosphate | | disodium-5-inosinate | | disodium-5'-inosinate | | IMP disodium salt | 5'- | imp disodium salt | | IMP sodium salt | 5'- | IMP-Na2 | | Inosin-5'-monophosphate disodium | | inosine 5'-monophosphate disodium | | inosine 5'-monophosphate disodium salt | | inosine 5'-monophosphate disodium salt hydrate | | inosine 5'-monphosphate disodium salt | | inosine-5'-monophosphate disodium | 5'- | inosinic acid, sodium salt (1:2) | 9H- | purin-6-ol, 9-(5-O-phosphono-b-D-ribofuranosyl)-, sodium salt (1:2) | | sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)-tetrahydrofuran-2-yl)methyl phosphate | | sodium 5'-inosinate |
Articles:
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