Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear liquid (est) |
Assay: | 99.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.03000 to 1.03400 @ 20.00 °C.
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Pounds per Gallon - (est).: | 8.581 to 8.614
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Refractive Index: | 1.51800 to 1.52200 @ 20.00 °C.
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Boiling Point: | 86.00 to 87.00 °C. @ 50.00 mm Hg
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Boiling Point: | 69.00 to 70.00 °C. @ 28.00 mm Hg
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Vapor Pressure: | 2.149000 mmHg @ 25.00 °C. (est) |
Flash Point: | 126.00 °F. TCC ( 52.22 °C. )
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logP (o/w): | 2.004 (est) |
Soluble in: |
| alcohol | | fats | | water, 1761 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: sulfurous |
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| meaty beefy |
Odor Description: at 0.10 % in propylene glycol. | meaty beefy |
|
| sulfurous meaty alliaceous coffee |
Odor Description:
| Sulfureous, meaty and alliaceous with a coffee nuance Mosciano, Gerard P&F 22, No. 3, 47, (1997) |
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Flavor Type: sulfurous |
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| sulfurous fatty roasted beefy eggy pork |
Taste Description:
| Sulfureous, fatty and roast beef-Iike with egg, salami and pork nuances Mosciano, Gerard P&F 22, No. 3, 47, (1997) |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Ambles Nature et Chimie |
2.3-BUTANEDITHIOL
|
Anhui Suzhou Jinli Aromatic Chemicals |
2,3-Butanedithiol
Odor: roast beef |
Beijing Lys Chemicals |
2,3-Butanedithiol
|
BOC Sciences |
For experimental / research use only. |
2,3-Butanedithiol
|
Carbosynth |
For experimental / research use only. |
2,3-Butanedithiol
|
DeLong Chemicals America |
2,3-Butanedithiol, Kosher
|
Endeavour Specialty Chemicals |
2,3-Butanedithiol
|
Speciality Chemical Product Groups |
Fleurchem |
2,3-butanedithiol
|
H. Interdonati, Inc. |
2,3-Butanedithiol Kosher
|
Featured Products |
Jiangyin Healthway |
2,3-Butanedithiol
|
New functional food ingredients |
Jinan Enlighten Chemical Technology(Wutong Aroma ) |
2,3-Butanedithiol, Kosherk
|
M&U International |
2,3-BUTANEDITHIOL, Kosher
|
OQEMA |
2,3-Butanedithiol
|
Penta International |
2,3-BUTANEDITHIOL
|
R C Treatt & Co Ltd |
2,3-Butanedithiol
Kosher |
Robinson Brothers |
2,3-Butanedithiol F&F
|
https://www.robinsonbrothers.uk/chemistry-competences |
Santa Cruz Biotechnology |
For experimental / research use only. |
2,3-Butanedithiol
|
Sigma-Aldrich |
2,3-Butanedithiol, ≥99%, FG
|
Certified Food Grade Products |
Sunaux International |
2,3-Butanedithiol
|
Synerzine |
2,3-Butanedithiol
|
TCI AMERICA |
For experimental / research use only. |
2,3-Butanedithiol >98.0%(GC)
|
Tengzhou Jitian Aroma Chemiclal |
2,3-Butane Dithiol
|
Tengzhou Xiang Yuan Aroma Chemicals |
2,3-Butanedithiol
|
Tianjin Danjun International |
2,3-Butanedithiol
|
United International |
2,3-Butanedithiol
|
WholeChem |
2,3-Butanedithiol
|
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 10 - Flammable. R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 20/21 - When using do not eat, drink or smoke. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents |
Recommendation for 2,3-butane dithiol usage levels up to: | | not for fragrance use.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.049 (μg/capita/day) |
NOEL (No Observed Effect Level): | 0.7 (mg/kg bw per day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 10 |
Click here to view publication 10 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.20000 |
beverages(nonalcoholic): | - | - |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | 0.20000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 0.20000 |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | 0.20000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 4532-64-3 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 548353 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 3336 |
WGK Germany: | 3 |
| butane-2,3-dithiol |
Chemidplus: | 0004532643 |
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
alliaceous |
| methyl furfuryl disulfide | FL/FR |
chocolate |
2,6- | dimethyl pyrazine | FL/FR |
2,5- | dimethyl pyrazine | FL/FR |
green |
(E,Z)-2,6- | nonadienal | FL/FR |
| sulfurol | FL/FR |
| sulfuryl acetate | FL/FR |
nutty |
2- | methyl-3-(methyl thio) pyrazine | FL/FR |
2,4,5- | trimethyl oxazole | FL/FR |
| ethyl 2-mercaptopropionate | FL/FR |
| fish thiol | FL/FR |
2- | mercaptopropionic acid | FL/FR |
4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
|
For Flavor |
|
No flavor group found for these |
| benzyl methyl sulfide | FL |
2,5- | dimethyl-3-thiofuroyl furan | FL |
2- | formyl pyrrole | FL |
4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
2- | methyl-1-butane thiol | FL |
2- | methyl-3-(methyl thio) pyrazine | FL/FR |
3-((2- | methyl-3-furyl)thio)-4-heptanone | FL |
1,9- | nonane dithiol | FL |
iso | propyl disulfide | FL |
|
3,7- | dimethyl-2,6-octadien-1-yl cyclopropyl carboxamide | FL |
2,4- | dimethyl-3-oxazoline | FL |
2- | methyl-1-methyl thio-2-butene | FL |
1-(2- | thienyl) butanone | FL |
alliaceous |
1,3- | butane dithiol | FL |
burnt |
1,6- | hexane dithiol | FL |
2,4,5- | trimethyl oxazole | FL/FR |
chemical |
2,5- | dimethyl furan | FL |
coffee |
2,4- | dimethyl thiazole | FL |
| methyl furfuryl disulfide | FL/FR |
earthy |
1,8- | octane dithiol | FL |
eggy |
iso | propyl mercaptan | FL |
green |
(E,Z)-2,6- | nonadienal | FL/FR |
meaty |
2,6- | dimethyl pyrazine | FL/FR |
2,6- | dimethyl thiophenol | FL |
2,5- | dimethyl-3-furan thiol | FL |
1,1- | ethane dithiol 1% in ethanol 94.5% / ethyl acetate 4% | FL |
| furfuryl 2-methyl-3-furyl disulfide | FL |
3- | mercapto-2-butanone | FL |
2- | mercaptopropionic acid | FL/FR |
2- | methyl 3-(methyl thio) furan | FL |
bis(2- | methyl-3-furyl) disulfide | FL |
S-(2- | methyl-3-furyl) ethane thioate | FL |
2- | methyl-3-tetrahydrofuran thiol | FL |
| propyl 2-mercaptopropionate | FL |
| pyrazinyl ethane thiol | FL |
2- | pyridinyl methane thiol | FL |
| sulfurol | FL/FR |
| sulfuryl acetate | FL/FR |
| thialdine | FL |
ortho- | thiocresol | FL |
metallic |
2,5- | dihydroxy-1,4-dithiane | FL |
musty |
2,5- | dimethyl pyrazine | FL/FR |
nutty |
| nutty thiazole | FL |
onion |
| ethyl 2-mercaptopropionate | FL/FR |
roasted |
| hexyl mercaptan | FL |
sulfurous |
| fish thiol | FL/FR |
| methyl 2-methyl-3-furyl disulfide | FL |
3- | methyl-2-butane thiol | FL |
| roasted butanol | FL |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| butane-2,3-dithiol | 2,3- | butanedithiol | 2,3- | dimercaptobutane | | dithione (IFF) | | dithione 865 (IFF) |
Articles:
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