Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless white solid (est) |
Assay: | 95.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.91000 to 0.91300 @ 25.00 °C.
|
Pounds per Gallon - (est).: | 7.572 to 7.597
|
Refractive Index: | 1.44700 to 1.44800 @ 20.00 °C.
|
Melting Point: | 25.00 to 27.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 137.00 °C. @ 2.00 mm Hg
|
Flash Point: | 300.00 °F. TCC ( 148.89 °C. )
|
logP (o/w): | 3.860 |
Soluble in: |
| alcohol | | water, 73.7 mg/L @ 30 °C (exp) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Description: at 100.00 %. | sweet woody |
|
Odor and/or flavor descriptions from others (if found). |
|
|
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. R 43 - May cause sensitisation by skin contact. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
|
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
gavage-mouse LD50 8150 mg/kg (Newell et al., 1949)
oral-mouse LD50 2300-6600 mg/kg (Tislow et al., 1950)
oral-rat LD50 2500 mg/kg (Tislow et al., 1950)
intraperitoneal-mouse LD50 960 mg/kg Journal of Investigative Dermatology. Vol. 13, Pg. 145, 1949.
oral-mouse LD50 8150 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT Journal of Investigative Dermatology. Vol. 13, Pg. 145, 1949.
oral-rat LD50 2500 mg/kg "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 4, Pg. 386, 1969.
|
Dermal Toxicity: |
skin-guinea pig LD50 50 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4954, 1982.
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for 10-undecenoic acid usage levels up to: | | 0.2000 % in the fragrance concentrate.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 26.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 4 |
Click here to view publication 4 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.50000 |
beverages(nonalcoholic): | - | 0.50000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 0.50000 |
fruit ices: | - | 0.50000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 0.50000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 6 (FGE.06): Straight-and branched-chain aliphatic unsatured primary alcohols, aldehydes, carboxylic acids, and esters from chemical groups 1 and 4 View page or View pdf |
Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to Flavouring Group Evaluation 5: Esters of 23 branched- and straight-chain aliphatic saturated primary alcohols and of one secondary alcohol, and 24 branched- and straight-chain unsaturated carboxylic acids from chemical groups 1, 2, and 5 View page or View pdf |
Flavouring Group Evaluation 6, Revision 1 (FGE.06Rev1) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 5, Revision 1 (FGE.05Rev1):Esters of branched- and straight-chain aliphatic saturated primary alcohols and of one secondary alcohol, and branched- and straight-chain unsaturated carboxylic acids from chemical groups 1, 2, and 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) [1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 5, Revision 2 (FGE.05Rev2): Branched- and straight-chain unsaturated carboxylic acids and esters of these with aliphatic saturated alcohols from chemical groups 1, 2, 3 and 5 View page or View pdf |
EPI System: | View |
ClinicalTrials.gov: | search |
Daily Med: | search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 112-38-9 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 5634 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 3261 |
WGK Germany: | 1 |
| undec-10-enoic acid |
Chemidplus: | 0000112389 |
RTECS: | YQ2975000 for cas# 112-38-9 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| declid | 10- | hendecenoic acid | omega- | hendecenoic acid | | renselin | | sevinon | | undec-10-enoic acid | | undecenoic acid | omega- | undecenoic acid | | undecyl-10-enic acid | | undecylenic acid | 10- | undecylenic acid | | undecylenic acid natural | | undecylenic acid U.S.P. grade |
Articles:
PubMed: | Regio- and stereoselective hydroxylation of 10-undecenoic acid with a light-driven P450 BM3 biocatalyst yielding a valuable synthon for natural product synthesis. |
PubMed: | Three monofunctional copolymers into one multifunctional Micelle: Part 1. Preparation and properties. |
PubMed: | Divergent dendrimer synthesis via the Passerini three-component reaction and olefin cross-metathesis. |
PubMed: | Bio-based aliphatic polyurethanes through ADMET polymerization in bulk and green solvent. |
PubMed: | Total synthesis and biological evaluation of clavaminol-G and its analogs. |
PubMed: | Fluorescence quenching in luminescent porous silicon nanoparticles for the detection of intracellular Cu2+. |
PubMed: | Biosynthesis and characterization of polyhydroxyalkanoates by Pseudomonas guezennei from alkanoates and glucose. |
PubMed: | Development of a three-steps derivatization assay for the localization of double bond in monounsaturated monomers of poly-beta-hydroxyalkanoates by GC-MS. |
PubMed: | Total synthesis and antifungal activity of (2S,3R)-2-aminododecan-3-ol. |
PubMed: | Structurally diverse polyamides obtained from monomers derived via the ugi multicomponent reaction. |
PubMed: | Oxidation of 10-undecenoic acid by cytochrome P450(BM-3) and its Compound I transient. |
PubMed: | A pH dependent thermo-sensitive copolymer drug carrier incorporating 4-amino-2,2,6,6-tetramethylpiperidin-1-oxyl (4-NH2-TEMPO) residues for electron spin resonance (ESR) labeling. |
PubMed: | Deoxycholate as an efficient coating agent for hydrophilic silicon nanocrystals. |
PubMed: | Rapid approach to biobased telechelics through two one-pot thiol-ene click reactions. |
PubMed: | Simultaneous biosynthesis of two copolymers in Pseudomonas putida GPo1 using a two-stage continuous culture system. |
PubMed: | Undecylenic acid: a valuable and physiologically active renewable building block from castor oil. |
PubMed: | Oxidation-triggered release of fluorescent molecules or drugs from mesoporous Si microparticles. |
PubMed: | Polymerizable vesicles based on a single-tailed fatty acid surfactant: a simple route to robust nanocontainers. |
PubMed: | Fed-batch production of unsaturated medium-chain-length polyhydroxyalkanoates with controlled composition by Pseudomonas putida KT2440. |
PubMed: | Spectra and kinetic studies of the compound I derivative of cytochrome P450 119. |
PubMed: | Topographical and functional characterization of the ssDNA probe layer generated through EDC-mediated covalent attachment to nanocrystalline diamond using fluorescence microscopy. |
PubMed: | 3,3,5-Trimethylcyclohexanols and derived esters: green synthetic procedures, odour evaluation and in vitro skin cytotoxicity assays. |
PubMed: | Covalent biofunctionalization of silicon nitride surfaces. |
PubMed: | Self-assembled monolayers with latent aldehydes for protein immobilization. |
PubMed: | Efficient production of (R)-3-hydroxycarboxylic acids by biotechnological conversion of polyhydroxyalkanoates and their purification. |
PubMed: | Bio-functional micelles self-assembled from a folate-conjugated block copolymer for targeted intracellular delivery of anticancer drugs. |
PubMed: | Self-assembled thermo- and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide) for drug delivery. |
PubMed: | UV photodissociation spectroscopy of oxidized undecylenic acid films. |
PubMed: | EDC-mediated DNA attachment to nanocrystalline CVD diamond films. |
PubMed: | Tailor-made olefinic medium-chain-length poly[(R)-3-hydroxyalkanoates] by Pseudomonas putida GPo1: batch versus chemostat production. |
PubMed: | Bacterial poly(hydroxyalkanoates) as a source of chiral hydroxyalkanoic acids. |
PubMed: | Synthesis, stereochemistry and biological activity of some novel long alkyl chain substituted thiazolidin-4-ones and thiazan-4-one from 10-undecenoic acid hydrazide. |
PubMed: | X-ray studies of self-assembled organic monolayers grown on hydrogen-terminated Si(111). |
PubMed: | One-pot sequences of reactions with sol-gel entrapped opposing reagents: an enzyme and metal-complex catalysts. |
PubMed: | Mutations in erg4 affect the sensitivity of Saccharomyces cerevisiae to medium-chain fatty acids. |
PubMed: | Convenient formation of 4-hydroxyalk-2-en-1-one functionality via A knoevenagel-type carbon chain elongation reaction of aldehyde with 1-arylsulfinylalkan-2-one. |
PubMed: | Evaluation of various carbon substrates for the biosynthesis of polyhydroxyalkanoates bearing functional groups by Pseudomonas putida. |
PubMed: | Enantioselective synthesis of (11E, 13S)-13-hydroxy-10-oxooctadecenoic acid, the cytotoxic principle of corn. |
PubMed: | RNA synthesis using a universal, base-stable allyl linker. |
PubMed: | Expedient Synthesis of (R)-Patulolide A. |
|