Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white crystals (est) |
Assay: | 98.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Melting Point: | 58.00 to 62.00 °C. @ 760.00 mm Hg
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Boiling Point: | 200.00 to 201.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.075000 mmHg @ 25.00 °C. (est) |
Flash Point: | 176.00 °F. TCC ( 80.00 °C. )
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logP (o/w): | 2.351 (est) |
Soluble in: |
| alcohol | | water, 440.5 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
|
Odor Type: herbal |
|
| minty eucalyptus green terpenic |
Odor Description: at 1.00 % in dipropylene glycol. | minty eucalyptus green terpene |
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| cooling minty eucalyptus green terpenic spicy |
Odor Description:
| Cooling, minty, eucalyptol, green and terpy with a spicy nuance Mosciano, Gerard P&F 22, No. 3, 47, (1997) |
|
|
Flavor Type: cooling |
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| cooling minty camphoreous woody green oily |
Taste Description: at 10.00 ppm. | Cool, minty, camphoreous, woody, green and oily Mosciano, Gerard P&F 22, No. 3, 47, (1997) |
|
Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
|
Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
maximum skin levels for fine fragrances: | | 0.0200 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey).
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Recommendation for sabinene hydrate usage levels up to: | | 0.5000 % in the fragrance concentrate.
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use level in formulae for use in cosmetics: | | 0.0200 %
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Dermal Systemic Exposure in Cosmetic Products: | | 0.0005 mg/kg/day
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.91 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 4 |
Click here to view publication 4 |
| average usual ppm | average maximum ppm |
baked goods: | - | - |
beverages(nonalcoholic): | - | 10.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 10.00000 |
fruit ices: | - | 10.00000 |
gelatins / puddings: | - | 10.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 10.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
No odor group found for these |
3- | benzoyl pyridine | |
| vinyl (4-methyl-thiazolyl-2) carbinol | |
alliaceous |
| ferula assa-foetida gum oil | FL/FR |
balsamic |
dextro,laevo-iso | borneol | FL/FR |
dextro,laevo- | borneol | FL/FR |
laevo- | borneol | FL/FR |
iso | bornyl acetate | FL/FR |
| bornyl acetate | FL/FR |
iso | bornyl formate | FL/FR |
iso | bornyl isobutyrate | FL/FR |
iso | bornyl methyl ether | FL/FR |
iso | bornyl propionate | FL/FR |
| croton glabellus bark extract | FL/FR |
| mastic oil | FL/FR |
| mastic oil replacer | FR |
camphoreous |
| bornyl ethyl ether | |
| camphor tree bark oil | FL/FR |
| eucalyptus polybractea oil | FR |
laevo- | fenchone | FL/FR |
citrus |
| lime oil expressed | FL/FR |
| ocimene quintoxide | FL/FR |
| petitgrain specialty | FR |
earthy |
(-)-alpha- | fenchol | FL/FR |
1- | octen-3-ol | FL/FR |
floral |
| cyclohexyl ethyl alcohol | FL/FR |
alpha- | damascone | FL/FR |
| dihydrocarvyl acetate | FL/FR |
| jasmin absolute egypt (from concrete) | FL/FR |
| linalool oxide | FL/FR |
beta- | ocimene | FL/FR |
| petitgrain fragrance | FR |
| petitgrain oil paraguay | FL/FR |
| petitgrain tangerine oil | FL/FR |
| rose absolute (rosa damascena) turkey | FL/FR |
fruity |
(E)-alpha- | damascone | FL/FR |
(E)-beta- | damascone | FL/FR |
| decen-1-yl cyclopentanone | FL/FR |
| octyl formate | FL/FR |
green |
iso | cyclocitral (IFF) | FL/FR |
| diphenyl methane | FL/FR |
| hexanal (aldehyde C-6) | FL/FR |
(E)-2- | hexen-1-yl butyrate | FL/FR |
(Z)-3- | hexen-1-yl butyrate | FL/FR |
(E)-2- | hexen-1-yl propionate | FL/FR |
(Z)-3- | hexen-1-yl pyruvate | FL/FR |
| leafy acetal | FL/FR |
para- | methyl hydratropaldehyde | FL/FR |
(E,Z)-2,6- | nonadienal diethyl acetal | FL/FR |
| olive oil absolute | FL/FR |
herbal |
1- | allyl-2,2,7,7-tetramethyl cycloheptanol | FR |
| apium graveolens seed extract | FL/FR |
| barosma betulina leaf oil | FL/FR |
1,4- | cineole | FL/FR |
1,8- | cineole | FL/FR |
iso | dihydrolavandulal | FL/FR |
| geranic oxide | FL/FR |
| herbal dioxane | FR |
6- | hydroxydihydrotheaspirane (mixture of isomers) | FL/FR |
| lavandin concrete | FL/FR |
| melaleuca leucadendron cajaputi oil | FL/FR |
| methyl cyclogeranate (Firmenich) | FR |
| myrtenol | FL/FR |
3- | octyl acetate | FL/FR |
| origanum oil | FL/FR |
| origanum oil greece | FL/FR |
| pine oil | FR |
beta- | pinene | FL/FR |
| pinocarveol | FL/FR |
| piperitone | FL/FR |
| psiadia altissima leaf oil | FR |
| ravensara aromatica leaf oil | FR |
| rosemary absolute | FL/FR |
| rosemary oil | FL/FR |
| rosemary oil CO2 extract | FL/FR |
| rosemary oil morocco | FL/FR |
| rosemary oil spain | FL/FR |
| theaspirane | FL/FR |
mentholic |
| cornmint oil | FL/FR |
| cornmint oil china | FL/FR |
| cornmint oil terpeneless | FL/FR |
laevo- | menthol | FL/FR |
dextro,laevo- | menthol | FL/FR |
(±)-iso | menthone | FL/FR |
| menthyl acetate racemic | FL/FR |
| peppermint cyclohexanone | FL/FR |
dextro- | piperitone | FL/FR |
iso | pulegyl acetate | FL/FR |
minty |
| agathosma crenulata leaf oil | FL/FR |
dextro- | dihydrocarvone | FL/FR |
homo | menthol | FL/FR |
(-)- | menthone | FL/FR |
homo | menthyl acetate | FL/FR |
laevo- | menthyl lactate | FL/FR |
| mint fragrance | FR |
| mint specialty | FR |
| pennyroyal oil | FL/FR |
| pennyroyal oil fractions | FL/FR |
| peppermint absolute | FL/FR |
| peppermint distillates | FL/FR |
| peppermint fragrance | FR |
| peppermint oil america | FL/FR |
| peppermint oil idaho | FL/FR |
| peppermint oil special fractions | FL/FR |
| peppermint oil terpeneless | FL/FR |
| peppermint oil willamette | FL/FR |
laevo- | piperitone | FL/FR |
iso | propyl tiglate | FL/FR |
iso | pulegol | FL/FR |
(-)-iso | pulegol | FL/FR |
(R)-(+)- | pulegone | FR |
iso | pulegone | FL/FR |
| WS-23 | FL/FR |
spicy |
| angelica oil | FL/FR |
| carvacrol | FL/FR |
beta- | caryophyllene | FL/FR |
| caryophyllene | FL/FR |
| cubeb oil CO2 extract (piper cubeba) | FL/FR |
| ginger oil terpenes | FR |
| ginger root oil | FL/FR |
| ginger root oil cochin | FL/FR |
| nutmeg oleoresin | FL/FR |
terpeneless black | pepper oil | FL/FR |
black | pepper oil | FL/FR |
black | pepper oil CO2 extract | FL/FR |
black | pepper oil replacer | FR |
| tea tree oil | FR |
| tea tree oil replacer | FR |
sulfurous |
| mango thiol | FL/FR |
| juniper branch oil | FR |
(R)-(-)-alpha- | phellandrene | FL/FR |
alpha- | phellandrene | FL/FR |
gamma- | terpinene | FL/FR |
thujonic |
| cedarleaf oil terpeneless | FR |
waxy |
2,4- | nonadien-1-ol | FL/FR |
woody |
iso | bornyl isovalerate | FL/FR |
2-tert- | butyl cyclohexanone | FR |
| camphene | FL/FR |
(+)- | camphene | FL/FR |
| hinoki root oil | FR |
(-)- | myrtenol | |
| pistacia lentiscus leaf oil | FR |
| sabinene | FL/FR |
| sclarene | |
|
For Flavor |
|
No flavor group found for these |
dextro,laevo- | borneol | FL/FR |
iso | bornyl methyl ether | FL/FR |
(+)- | camphene | FL/FR |
| croton glabellus bark extract | FL/FR |
(±)-N,N- | dimethyl menthyl succinamide | FL |
3-laevo- | menthoxy-2-methyl propane-1,2-diol | FL |
| menthyl acetate racemic | FL/FR |
(R)-(-)-alpha- | phellandrene | FL/FR |
iso | pulegone | FL/FR |
| sclarene | |
|
| menthyl methyl lactate | FL |
alliaceous |
| ferula assa-foetida gum oil | FL/FR |
aromatic |
| leafy acetal | FL/FR |
balsamic |
iso | bornyl isobutyrate | FL/FR |
iso | bornyl propionate | FL/FR |
| mastic oil | FL/FR |
camphoreous |
dextro,laevo-iso | borneol | FL/FR |
laevo- | borneol | FL/FR |
| bornyl acetate | FL/FR |
| bornyl ethyl ether | |
| camphene | FL/FR |
| camphor tree bark oil | FL/FR |
(-)-alpha- | fenchol | FL/FR |
laevo- | fenchone | FL/FR |
| geranic oxide | FL/FR |
6- | hydroxydihydrotheaspirane (mixture of isomers) | FL/FR |
| pinocarveol | FL/FR |
citrus |
| lime oil expressed | FL/FR |
cooling |
1,4- | cineole | FL/FR |
dextro,laevo- | menthol | FL/FR |
laevo- | menthol | FL/FR |
homo | menthyl acetate | FL/FR |
laevo- | menthyl lactate | FL/FR |
| peppermint oil america | FL/FR |
| theaspirane | FL/FR |
| WS-3 | FL |
fatty |
(E,E)-2,4- | heptadienal | FL |
2,4- | nonadien-1-ol | FL/FR |
floral |
| dihydrocarvyl acetate | FL/FR |
| jasmin absolute egypt (from concrete) | FL/FR |
| jasmin flavor | FL |
| rose absolute (rosa damascena) turkey | FL/FR |
fruity |
alpha- | damascone | FL/FR |
(E)-alpha- | damascone | FL/FR |
(E)-beta- | damascone | FL/FR |
| decen-1-yl cyclopentanone | FL/FR |
green |
3- | benzoyl pyridine | |
| celery distillates | FL |
iso | cyclocitral (IFF) | FL/FR |
| cyclohexyl ethyl alcohol | FL/FR |
dextro- | dihydrocarvone | FL/FR |
| diphenyl methane | FL/FR |
| hexanal (aldehyde C-6) | FL/FR |
(Z)-3- | hexen-1-yl butyrate | FL/FR |
(E)-2- | hexen-1-yl butyrate | FL/FR |
(E)-2- | hexen-1-yl propionate | FL/FR |
(Z)-3- | hexen-1-yl pyruvate | FL/FR |
| linalool oxide | FL/FR |
para- | methyl hydratropaldehyde | FL/FR |
(E,Z)-2,6- | nonadienal diethyl acetal | FL/FR |
beta- | ocimene | FL/FR |
| ocimene quintoxide | FL/FR |
3- | octyl acetate | FL/FR |
| octyl formate | FL/FR |
iso | propyl tiglate | FL/FR |
herbal |
| apium graveolens seed extract | FL/FR |
| barosma betulina leaf oil | FL/FR |
iso | dihydrolavandulal | FL/FR |
| lavandin concrete | FL/FR |
| melaleuca leucadendron cajaputi oil | FL/FR |
| origanum oil | FL/FR |
| origanum oil greece | FL/FR |
| petitgrain oil paraguay | FL/FR |
| petitgrain tangerine oil | FL/FR |
| rosemary absolute | FL/FR |
| rosemary oil | FL/FR |
| rosemary oil CO2 extract | FL/FR |
| rosemary oil morocco | FL/FR |
| rosemary oil spain | FL/FR |
mentholic |
| cornmint oil | FL/FR |
| cornmint oil terpeneless | FL/FR |
| peppermint cyclohexanone | FL/FR |
minty |
| agathosma crenulata leaf oil | FL/FR |
1,8- | cineole | FL/FR |
| cornmint oil china | FL/FR |
homo | menthol | FL/FR |
(-)- | menthone | FL/FR |
(±)-iso | menthone | FL/FR |
| mint flavor | FL |
| myrtenol | FL/FR |
(-)- | myrtenol | |
| pennyroyal oil | FL/FR |
| pennyroyal oil fractions | FL/FR |
| peppermint absolute | FL/FR |
| peppermint distillates | FL/FR |
| peppermint flavor | FL |
| peppermint oil idaho | FL/FR |
| peppermint oil special fractions | FL/FR |
| peppermint oil terpeneless | FL/FR |
| peppermint oil willamette | FL/FR |
laevo- | piperitone | FL/FR |
dextro- | piperitone | FL/FR |
| piperitone | FL/FR |
iso | pulegol | FL/FR |
(-)-iso | pulegol | FL/FR |
| WS-23 | FL/FR |
mushroom |
1- | octen-3-ol | FL/FR |
oily |
| olive oil absolute | FL/FR |
pine |
beta- | pinene | FL/FR |
spicy |
| angelica oil | FL/FR |
| carvacrol | FL/FR |
beta- | caryophyllene | FL/FR |
| caryophyllene | FL/FR |
| cubeb oil CO2 extract (piper cubeba) | FL/FR |
| galanga flavor | FL |
| ginger root oil | FL/FR |
| ginger root oil cochin | FL/FR |
| nutmeg oleoresin | FL/FR |
black | pepper oil | FL/FR |
terpeneless black | pepper oil | FL/FR |
black | pepper oil CO2 extract | FL/FR |
sulfurous |
| mango thiol | FL/FR |
terpenic |
alpha- | phellandrene | FL/FR |
gamma- | terpinene | FL/FR |
woody |
iso | bornyl acetate | FL/FR |
iso | bornyl formate | FL/FR |
iso | bornyl isovalerate | FL/FR |
iso | pulegyl acetate | FL/FR |
| sabinene | FL/FR |
| vinyl (4-methyl-thiazolyl-2) carbinol | |
|
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| bicyclo 3.1.0 hexan-2-ol, 2-methyl-5-(1-methylethyl)- | | bicyclo(3.1.0)hexan-2-ol, 2-methyl-5-(1-methylethyl)- | | bicyclo[3.1.0]hexan-2-ol, 2-methyl-5-(1-methylethyl)- | 4- | methyl-1-propan-2-ylbicyclo[3.1.0]hexan-4-ol | 2- | methyl-5-(1-methyl ethyl) bicyclo(3.1.0)hexan-2-ol | (1a,2a,5a)-2- | methyl-5-(1-methylethyl)bicyclo(3.1.0)hexan-2-ol | 2- | methyl-5-(1-methylethyl)bicyclo(3.1.0)hexan-2-ol | 2- | methyl-5-(1-methylethyl)bicyclo[3.1.0]hexan-2-ol | 2- | methyl-5-(propan-2-yl)bicyclo[3.1.0]hexan-2-ol | (1R*,2S*,5S*)-5-iso | propyl-2-methylbicyclo[3.1.0]hexan-2-ol | 5-iso | propyl-2-methylbicyclo[3.1.0]hexan-2-ol | | sabina hydrate | | sabinene hydrate | cis- | sabinenehydrate | | thujan-4-ol | trans- | thujan-4-ol | 4- | thujanol |
Articles:
PubMed: | Fumigant toxicity and acetylcholinesterase inhibitory activity of 4 Asteraceae plant essential oils and their constituents against Japanese termite (Reticulitermes speratus Kolbe). |
PubMed: | Antioxidant effects of the monoterpenes carvacrol, thymol and sabinene hydrate on chemical and sensory stability of roasted sunflower seeds. |
PubMed: | Stereochemical mechanism of two sabinene hydrate synthases forming antipodal monoterpenes in thyme (Thymus vulgaris). |
PubMed: | Chemical diversity of wild growing Origanum majorana in Cyprus. |
PubMed: | Analysis of the essential oil of large cardamom (Amomum subulatum Roxb.) growing in different agro-climatic zones of Himachal Pradesh, India. |
PubMed: | Distillation time alters essential oil yield, composition, and antioxidant activity of male Juniperus scopulorum trees. |
PubMed: | Chemical composition, olfactory analysis and antibacterial activity of Thymus vulgaris chemotypes geraniol, 4-thujanol/terpinen-4-ol, thymol and linalool cultivated in southern France. |
PubMed: | Chemical composition, antimicrobial, antioxidant and cytotoxic activity of the essential oil from the leaves of Acanthopanax leucorrhizus (Oliv.) Harms. |
PubMed: | Culture conditions and salt effects on essential oil composition of sweet marjoram (Origanum majorana) from Tunisia. |
PubMed: | Variation of chemical composition of essential oils in wild populations of Thymus algeriensis Boiss. et Reut., a North African endemic species. |
PubMed: | In vitro evaluation of the protective effects of 4-thujanol against mitomycin-C and cyclophosphamide-induced genotoxic damage in human peripheral lymphocytes. |
PubMed: | Oil constituents of Artemisia nilagirica var. septentrionalis growing at different altitudes. |
PubMed: | Free radical scavenging and antiacetylcholinesterase activities of Origanum majorana L. essential oil. |
PubMed: | Solvent-free microwave extraction and hydrodistillation of essential oils from endemic Origanum husnucanbaseri H. Duman, Aytac & A. Duran: comparison of antibacterial activity and contents. |
PubMed: | The essential oils of the Greek endemic Satureja horvatii ssp. macrophylla in relation to bioclimate. |
PubMed: | Volatile oil composition and antiproliferative activity of Laurus nobilis, Origanum syriacum, Origanum vulgare, and Salvia triloba against human breast adenocarcinoma cells. |
PubMed: | A biochemical interpretation of terpene chemotypes in Melaleuca alternifolia. |
PubMed: | Supercritical fluid extraction of oregano (Origanum vulgare) essentials oils: anti-inflammatory properties based on cytokine response on THP-1 macrophages. |
PubMed: | Systemic induction of monoterpene biosynthesis in Origanumxmajoricum by soil bacteria. |
PubMed: | Seasonal variation in the essential oil composition of Origanum majorana L. cultivated in Egypt. |
PubMed: | Total phenolic content, radical scavenging properties, and essential oil composition of Origanum species from different populations. |
PubMed: | Analysis of essential oils of Artemisia absinthium L. from Lithuania by CC, GC(RI), GC-MS and 13C NMR. |
PubMed: | Essential oil composition of Laurus nobilis L. of different growth stages growing in Iran. |
PubMed: | Antibacterial activity and chemical constitutions of essential oils of Thymus persicus and Thymus eriocalyx from west of Iran. |
PubMed: | Effects of cis-beta-ocimene, cis-sabinene hydrate, and monoterpene and sesquiterpene mixtures on alfalfa pellet intake by lambs. |
PubMed: | Chemical composition of the volatile extract and antioxidant activities of the volatile and nonvolatile extracts of Egyptian corn silk (Zea mays L.). |
PubMed: | Toxicity of Myristica fagrans seed compounds against Blattella germanica (Dictyoptera: Blattellidae). |
PubMed: | Evaluation of characteristic aroma compounds of Citrus natsudaidai Hayata (Natsudaidai) cold-pressed peel oil. |
PubMed: | Isolation of Seseli bocconi Guss., subsp. praecox Gamisans (Apiaceae) volatile oil by supercritical carbon dioxide extraction. |
PubMed: | Supercritical carbon dioxide extraction of compounds with antimicrobial activity from Origanum vulgare L.: determination of optimal extraction parameters. |
PubMed: | Isolation and partial characterisation of a putative monoterpene synthase from Melaleuca alternifolia. |
PubMed: | Chemical composition and extraction yield of the extract of Origanum vulgare obtained from sub- and supercritical CO2. |
PubMed: | Changes of the volatile profile and artifact formation in Daidai (Citrus aurantium) cold-pressed peel oil on storage. |
PubMed: | The effects of temperature and pressure on the characteristics of the extracts from high-pressure CO(2) extraction of Majorana hortensis Moench. |
PubMed: | Monoterpenoid accumulation in Melaleuca alternifolia seedlings. |
PubMed: | Allylic lithium oxyanionic directed and facilitated simmons-smith cyclopropanation: stereoselective synthesis of (+/-)-cis-sabinene hydrate and a novel ring expansion. |
PubMed: | Ratios of cis- and trans-Sabinene Hydrate in Origanum majorana L. and Origanum microphyllum (Bentham) Vogel. |
PubMed: | Chemotaxonomic study on Thymus villosus from Portugal. |
PubMed: | A convenient synthesis of trans-sabinene hydrate from (-)-3-thujol via a highly selective ene reaction of singlet oxygen. |
PubMed: | Oviposition stimulants for the black swallowtail butterfly: Identification of electrophysiologically active compounds in carrot volatiles. |
PubMed: | Monoterpene biosynthesis: mechanism and stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (+)-cis- and (+)-trans-sabinene hydrate. |
PubMed: | Monoterpene biosynthesis: demonstration of a geranyl pyrophosphate:sabinene hydrate cyclase in soluble enzyme preparations from sweet marjoram (Majorana hortensis). |
|