Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 80.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Boiling Point: | 286.10 °C. @ 760.00 mm Hg (est)
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Vapor Pressure: | 0.003000 mmHg @ 25.00 °C. (est) |
Flash Point: | 261.00 °F. TCC ( 127.22 °C. )
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logP (o/w): | 4.050 (est) |
Soluble in: |
| alcohol | | water, 261 mg/L @ 20 °C (exp) |
Stability: |
| alcoholic - good | | antiperspirant spray - poor | | APC (pH = 10) - moderate | | candles - good | | damp fabric - moderate | | dry fabric - moderate | | liquid bleach - poor | | pH = 2 - moderate | | powder detergent - moderate | | powder detergent + activator - moderate | | soap - good | | toiletries - good |
Organoleptic Properties:
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Odor Type: woody |
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Odor Strength: | medium |
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Substantivity: | 96 hour(s) at 100.00 % |
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| woody woody old wood amber tobacco herbal |
Odor Description: at 100.00 %. | woody old wood amber tobacco hot herbal Luebke, William tgsc, (1987) |
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Odor and/or flavor descriptions from others (if found). |
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Givaudan |
Kephalis |
Odor Description: | Rich, Warm, Woody, Ambery, Tobacco Kephalis is a very versatile and rich product, used as a long lasting heart/basic note. It blends well with floral notes (jasmine, rose, violet, lavender, etc.) as well as sophisticated amber, woody-aldehydic, tobacco and masculine creations. |
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PerfumersWorld |
Kephalis |
Odor Description: | woody herbal character somewhat reminiscent of honey Blends-well-with - +iso-E-Super |
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Pell Wall Perfumes |
Kephalis |
Odor Description: | Rich, Warm, Woody, Ambery, Tobacco The Scent and Chemistry authors point out that Kephalis, just like Cashmeran, is often a key component of synthetic reconstructions of agarwood. |
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Cosmetic Information:
Suppliers:
ACS International |
Tetrambrone
Odor: woody amber tobacco herbal |
Operational Capabilities |
Augustus Oils |
Kephalis
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Services |
BOC Sciences |
For experimental / research use only. |
Kephalis
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Creatingperfume.com |
Kephalis (Givaudan)
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Ernesto Ventós |
KEPHALIS
Odor: FLORAL, AMBER |
Givaudan |
Kephalis
Odor: Rich, Warm, Woody, Ambery, Tobacco Use: Kephalis is a very versatile and rich product, used as a long lasting heart/basic note. It blends well with floral notes (jasmine, rose, violet, lavender, etc.) as well as sophisticated amber, woody-aldehydic, tobacco and masculine creations. |
Indukern F&F |
KEPHALIS
Odor: AMBER, WOODY, WARM, TOBACCO |
Lluch Essence |
WOODAROM
|
M&U International |
Kephalis
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Moellhausen |
KEPHALIS
Odor: honey, amberwoody note |
OQEMA |
Kephalan
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Organica Aromatics |
KEPHALOR
Min 80% |
PCW France |
Kephalis
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Steps to a fragranced product |
Pell Wall Perfumes |
Kephalis
Odor: Rich, Warm, Woody, Ambery, Tobacco Use: The Scent and Chemistry authors point out that Kephalis, just like Cashmeran, is often a key component of synthetic reconstructions of agarwood. |
Penta International |
KEPHALIS
|
PerfumersWorld |
Kephalis
Odor: woody herbal character somewhat reminiscent of honey Use: Blends-well-with - +iso-E-Super |
Perfumery Laboratory |
KEFALIS Givaudan (KEPHALIS Givaudan)
Odor: Rich, warm, woody, amber fragrance with a hint of tobacco |
The Perfumers Apprentice |
Kephalis
Odor: Rich, Warm, Woody-Ambery, Tobacco Use: blends well with floral notes (jasmine, rose, violet, lavender, etc.) as well as sophisticated amber, woody-aldehydic and tobacco |
Vigon International |
Kephalis
Odor: Rich, Warm, Woody, Ambery, Tobacco |
Safety Information:
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
10 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 835, 1982.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 835, 1982.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for woody cyclohexanone usage levels up to: | | 8.0000 % in the fragrance concentrate.
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Recommendation for woody cyclohexanone flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
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For Odor |
aldehydic |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
amber |
(Z)- | abienol | FL/FR |
| acetoxymethyl isolongifolene | FR |
| amber acetate | FR |
| amber butanol | FR |
| amber carane | FR |
| amber cyclohexanol | FR |
| amber oxepin | FR |
| amber specialty | FR |
| ambermax 50 (Givaudan) | FR |
| ambrette seed oil | FL/FR |
| ambroxan | FL/FR |
| angelica root oil | FL/FR |
| cistus ladaniferus resin | FR |
| cistus ladaniferus resinoid | FL/FR |
| formoxymethyl isolongifolene | FR |
| hydroxymethyl isolongifolene 50% in dpg | FR |
| labdanum absolute | FL/FR |
| labdanum oil | FL/FR |
animal |
| ambergris tincture replacer | FR |
iso | butyl quinoline | FR |
| costus valerolactone | FR |
anisic |
para- | anisaldehyde | FL/FR |
balsamic |
| amyris wood oil | FL/FR |
siam | benzoin resinoid | FL/FR |
| benzophenone | FR |
| benzyl benzoate | FL/FR |
| benzyl salicylate | FL/FR |
iso | bornyl acetate | FL/FR |
laevo- | bornyl acetate | FL/FR |
iso | butyl benzoate | FL/FR |
iso | butyl cinnamate | FL/FR |
| cinnamyl alcohol | FL/FR |
| ethyl cinnamate | FL/FR |
| fir balsam absolute | FR |
| fir carboxylate | FR |
| mastic gum resin | FR |
| methyl (E)-cinnamate | FL/FR |
| methyl hydrogenated rosinate | FR |
| myrrh oil | FL/FR |
| opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR |
| opoponax resin (commiphora erythraea var. glabrescens engler) | FL/FR |
| opoponax resinoid (commiphora erythraea var. glabrescens engle) | FR |
| opoponax resinoid replacer | FR |
| oriental specialty | FR |
3- | phenyl propyl alcohol | FL/FR |
| sclareol | FL/FR |
| styrax resin (liquidambar styraciflua) | FL/FR |
| styrax resinoid (liquidambar styraciflua) | FL/FR |
berry |
| raspberry ketone | FL/FR |
chocolate |
iso | butyl phenyl acetate | FL/FR |
citrus |
| bergamot oil bergaptene reduced italy | FL/FR |
coconut |
gamma- | heptalactone | FL/FR |
gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
dusty |
| woody furan | FR |
earthy |
| methyl undecylenate | FL/FR |
fatty |
| coconut absolute | FL/FR |
| decanol | FL/FR |
floral |
| acetophenone | FL/FR |
alpha- | amyl cinnamaldehyde | FL/FR |
iso | amyl salicylate | FL/FR |
| bois de rose oil brazil | FL/FR |
iso | butyl salicylate | FL/FR |
| citronellol | FL/FR |
| coriander seed oil | FL/FR |
| cyclamen aldehyde | FL/FR |
| dimethyl benzyl carbinol | FL/FR |
| dimethyl benzyl carbinyl acetate | FL/FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| ethyl phenyl acetate | FL/FR |
| floral pyranol | FR |
| gardenia decalone | FR |
| heliotropin | FL/FR |
| heliotropyl acetone | FL/FR |
| heliotropyl diethyl acetal | FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| ho leaf oil | FR |
| hyacinth ether | FR |
| hydroxycitronellal | FL/FR |
| ilex paraguariensis oleoresin | FL/FR |
| leerall | FR |
laevo- | linalool | FL/FR |
| linalool | FL/FR |
| linalool oxide | FL/FR |
para- | methyl acetophenone | FL/FR |
| methyl dihydrojasmonate | FL/FR |
| muguet carboxaldehyde | FR |
| nerolidol | FL/FR |
| ocean propanal | FL/FR |
| orris pyridine 25% IPM | FR |
| phenethyl alcohol | FL/FR |
| phenethyl phenyl acetate | FL/FR |
| phenethyl salicylate | FL/FR |
| rhodinol | FL/FR |
| rose butanoate | FL/FR |
| tetrahydrolinalool | FL/FR |
fruity |
| balsam specialty | FR |
| fruity cyclopentanone | FR |
| tropical ionone | FL/FR |
green |
| diphenyl oxide | FL/FR |
(Z)-3- | hexen-1-yl benzoate | FL/FR |
| phenyl acetaldehyde dimethyl acetal | FL/FR |
3- | phenyl propionaldehyde | FL/FR |
hay |
| hay absolute | FR |
| woodruff absolute | FR |
herbal |
(+)-alpha- | campholenic aldehyde | FL/FR |
| carum carvi fruit oil | FL/FR |
| clary sage oil france | FL/FR |
| daucus carota fruit oil | FL/FR |
| linalyl acetate | FL/FR |
| nopyl acetate | FR |
| romanal | FR |
gamma- | valerolactone | FL/FR |
mossy |
| moss specialty | FR |
| veramoss (IFF) | FR |
naphthyl |
beta- | naphthyl ethyl ether | FL/FR |
oily |
| mcp acetate | FR |
powdery |
para- | anisyl alcohol | FL/FR |
| midnight passion fragrance | FR |
spicy |
| angelica seed absolute | FL/FR |
| benzyl isoeugenol | FL/FR |
| cassia bark oil china | FL/FR |
| clove bud oil | FL/FR |
4- | ethyl guaiacol | FL/FR |
| eugenol | FL/FR |
iso | eugenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl isoeugenol | FL/FR |
| pimenta acris leaf oil | FL/FR |
terpenic |
| angelica seed oil | FL/FR |
| cypress leaf oil | FR |
alpha- | terpineol | FL/FR |
thujonic |
| armoise oil | FR |
| sage oil dalmatian | FL/FR |
tobacco |
2,6,6- | trimethyl-2-hydroxycyclohexanone | FL/FR |
tonka |
| coumarin | FR |
| deertongue absolute | FR |
gamma- | hexalactone | FL/FR |
| tonka bean absolute | FR |
tropical |
cis- | galbanum oxathiane | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
1- | dodecanol | FL/FR |
| ethyl laurate | FL/FR |
woody |
| acetyl cedrene | FR |
| amber carbinol | FR |
| amber dioxane | FR |
| amber formate | FR |
| amber pentadecane | FR |
atlas | cedarwood oil | FR |
| cedarwood oil texas fractions | FR |
alpha- | cedrene epoxide | FR |
| cedryl formate | FR |
| cedryl methyl ether | FR |
| cistus ladaniferus gum | FR |
| cistus twig/leaf oil | FL/FR |
| dragons blood fragrance | FR |
| frankincense resinoid | FL/FR |
| frankincense resinoid replacer | FR |
| georgywood | FR |
| guaiacwood oil | FL/FR |
| gurjun balsam oil | FR |
| hydroxyambran | FR |
| incense specialty | FR |
| labdanum concrete | FR |
2- | methoxy-4-vinyl phenol | FL/FR |
(4aR,5R,7aS,9R)- | octahydro-2,2,5,8,8,9a-hexamethyl-4h-4a,9-methanoazuleno(5,6-d)-1,3-dioxole | FR |
| patchouli ethanone | FR |
| patchouli oil | FL/FR |
| patchouli woody amber fragrance | FR |
| santall | FR |
| spruce needle oil canada | FL/FR |
| tetramethyl-4-methylene-2-heptanol | FR |
| thuja occidentalis leaf oil | FL/FR |
| tobacarol (IFF) | FR |
| vetiver oil haiti | FL/FR |
| vetiver specialty | FR |
| woody acetate | FR |
(Z)- | woody amylene | FR |
| woody dioxolane | FR |
| woody nonane (ethoxy) | FR |
| woody propanol | FR |
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For Flavor |
|
No flavor group found for these |
| cistus ladaniferus resinoid | FL/FR |
| ilex paraguariensis oleoresin | FL/FR |
| methyl (E)-cinnamate | FL/FR |
2,6,6- | trimethyl-2-hydroxycyclohexanone | FL/FR |
amber |
| ambrette seed oil | FL/FR |
| angelica seed oil | FL/FR |
| labdanum absolute | FL/FR |
| labdanum oil | FL/FR |
balsamic |
siam | benzoin resinoid | FL/FR |
| benzyl benzoate | FL/FR |
| benzyl salicylate | FL/FR |
laevo- | bornyl acetate | FL/FR |
iso | butyl cinnamate | FL/FR |
| ethyl cinnamate | FL/FR |
| myrrh oil | FL/FR |
| opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR |
| opoponax resin (commiphora erythraea var. glabrescens engler) | FL/FR |
| styrax resin (liquidambar styraciflua) | FL/FR |
| styrax resinoid (liquidambar styraciflua) | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
| raspberry ketone | FL/FR |
cherry |
| heliotropin | FL/FR |
citrus |
| bergamot oil bergaptene reduced italy | FL/FR |
laevo- | linalool | FL/FR |
| linalool | FL/FR |
alpha- | terpineol | FL/FR |
cocoa |
iso | butyl phenyl acetate | FL/FR |
coconut |
gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
cooling |
iso | butyl salicylate | FL/FR |
creamy |
para- | anisaldehyde | FL/FR |
gamma- | hexalactone | FL/FR |
para- | methyl acetophenone | FL/FR |
fatty |
| coconut absolute | FL/FR |
(Z)-3- | hexen-1-yl benzoate | FL/FR |
floral |
| bois de rose oil brazil | FL/FR |
| citronellol | FL/FR |
| dimethyl benzyl carbinyl acetate | FL/FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| linalyl acetate | FL/FR |
| methyl dihydrojasmonate | FL/FR |
| ocean propanal | FL/FR |
| phenethyl alcohol | FL/FR |
| rhodinol | FL/FR |
| tetrahydrolinalool | FL/FR |
| tropical ionone | FL/FR |
fruity |
para- | anisyl alcohol | FL/FR |
iso | butyl benzoate | FL/FR |
| rose butanoate | FL/FR |
green |
iso | amyl salicylate | FL/FR |
| angelica root oil | FL/FR |
(+)-alpha- | campholenic aldehyde | FL/FR |
| cinnamyl alcohol | FL/FR |
| cyclamen aldehyde | FL/FR |
| diphenyl oxide | FL/FR |
cis- | galbanum oxathiane | FL/FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
| linalool oxide | FL/FR |
| nerolidol | FL/FR |
| phenyl acetaldehyde dimethyl acetal | FL/FR |
3- | phenyl propionaldehyde | FL/FR |
herbal |
| carum carvi fruit oil | FL/FR |
| clary sage oil france | FL/FR |
| coriander seed oil | FL/FR |
| daucus carota fruit oil | FL/FR |
honey |
| ethyl phenyl acetate | FL/FR |
| phenethyl phenyl acetate | FL/FR |
lactonic |
gamma- | heptalactone | FL/FR |
medicinal |
| dimethyl benzyl carbinol | FL/FR |
| phenethyl salicylate | FL/FR |
powdery |
| acetophenone | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
smoky |
2- | methoxy-4-vinyl phenol | FL/FR |
soapy |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
1- | dodecanol | FL/FR |
spicy |
| angelica seed absolute | FL/FR |
| benzyl isoeugenol | FL/FR |
| cassia bark oil china | FL/FR |
| clove bud oil | FL/FR |
| eugenol | FL/FR |
iso | eugenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl isoeugenol | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
| pimenta acris leaf oil | FL/FR |
thujonic |
| sage oil dalmatian | FL/FR |
tonka |
gamma- | valerolactone | FL/FR |
tropical |
alpha- | amyl cinnamaldehyde | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
| decanol | FL/FR |
| ethyl laurate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hydroxycitronellal | FL/FR |
2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
| methyl undecylenate | FL/FR |
woody |
(Z)- | abienol | FL/FR |
| ambroxan | FL/FR |
| amyris wood oil | FL/FR |
iso | bornyl acetate | FL/FR |
| cistus twig/leaf oil | FL/FR |
4- | ethyl guaiacol | FL/FR |
| frankincense resinoid | FL/FR |
| guaiacwood oil | FL/FR |
| patchouli oil | FL/FR |
| sclareol | FL/FR |
| spruce needle oil canada | FL/FR |
| thuja occidentalis leaf oil | FL/FR |
| vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| cyclohexanone, 4-(1-ethoxyethenyl)-3,3,5,5-tetramethyl- | 4-(1- | ethoxyethenyl)-3,3,5,5-tetramethylcyclohexan-1-one | 4-(1- | ethoxyethenyl)-3,3,5,5-tetramethylcyclohexanone | 4-(1- | ethoxyvinyl)-3,3,5,5-tetramethyl cyclohexanone | 4-(1- | ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone | 3,3,5,5- | etramethyl-4-ethoxyvinylcyclohexanone | | kephalan | | kephalis (Givaudan) | | kephalor | | tetrambrone (A.C.S. International) | 3,3,5,5- | tetramethyl-4-(1-ethoxyvinyl) cyclohexanone | 3,3,5,5- | tetramethyl-4-(1-ethoxyvinyl)-1-cyclohexanone | 3,3,5,5- | tetramethyl-4-(1-ethoxyvinyl)cyclohexanone | 3,3,5,5- | tetramethyl-4-ethoxyvinyl cyclohexanone | 3,3,5,5- | tetramethyl-4-ethoxyvinylcyclohexanone | | woody cyclohexanone |
Articles:
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