Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white crystallin powder (est) |
Assay: | 98.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 48.00 to 50.00 °C. @ 760.00 mm Hg
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Boiling Point: | 244.00 to 245.00 °C. @ 760.00 mm Hg
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Congealing Point: | 47.50 °C.
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Acid Value: | 1.00 max. KOH/g
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Vapor Pressure: | 0.016000 mmHg @ 25.00 °C. (est) |
Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. )
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logP (o/w): | 2.270 |
Soluble in: |
| alcohol | | water, 643 mg/L 20 °C (exp) |
Insoluble in: |
| water |
Similar Items: note |
methyl 3-methoxybenzoate |
methyl 2-methoxybenzoate |
ethyl para-anisate |
hexyl para-anisate |
Organoleptic Properties:
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Odor Type: anisic |
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| herbal anise sweet |
Odor Description: at 100.00 %. | herbal anise sweet |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
4 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg (Levenstein, 1975k)
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 14, Pg. 481, 1976.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 14, Pg. 481, 1976.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for methyl para-anisate usage levels up to: | | 3.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.97 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.01 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 6.20000 |
beverages(nonalcoholic): | - | 2.70000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 3.00000 |
fruit ices: | - | 3.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 8.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 121-98-2 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 8499 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| methyl 4-methoxybenzoate |
Chemidplus: | 0000121982 |
RTECS: | BZ4925000 for cas# 121-98-2 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
No odor group found for these |
| dehydro-ar-ionene | |
animal |
para- | cresyl caprylate | FL/FR |
anise |
| anise oleoresin | FL/FR |
| anise seed oil | FL/FR |
star | anise seed oil china | FL/FR |
| anise seed oil colombia | FL/FR |
star | anise seed oil terpeneless | FL/FR |
sweet | fennel absolute | FL/FR |
sweet | fennel oleoresin | FL/FR |
sweet | fennel seed oil | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | acetanisole | FL/FR |
| amyl furoate | FL/FR |
(Z)- | anethol | |
ortho- | anisaldehyde | FL/FR |
para- | anisaldehyde | FL/FR |
para- | anisyl phenyl acetate | FL/FR |
para- | anisyl propanal | FR |
| dihydroanethol | FL/FR |
| ethyl para-anisate | FL/FR |
| ocimum basilicum herb oil | FL/FR |
| ocimum basilicum leaf oil america | FL/FR |
| sassafras acetate | FL/FR |
balsamic |
| cinnamyl alcohol | FL/FR |
| geranyl benzoate | FL/FR |
| phenethyl cinnamate | FL/FR |
| prenyl benzoate | FL/FR |
| terpinyl benzoate | FR |
berry |
| raspberry ketone methyl ether | FL/FR |
chocolate |
| vanillyl ethyl ether | FL/FR |
fatty |
2,4- | decadien-1-ol | FL/FR |
(E,E)-2,4- | decadien-1-ol | FL/FR |
floral |
| acetophenone | FL/FR |
para- | anisaldehyde / methyl anthranilate schiff's base | FR |
para- | anisaldehyde dimethyl acetal | FR |
| anise indene | FR |
para- | anisyl acetaldehyde | FL/FR |
para- | anisyl nitrile | FR |
| anisyl propanal / methyl anthranilate schiff's base | FR |
| autumn carboxylate | FR |
| boronia absolute | FL/FR |
| champaca absolute | FR |
| cuminyl acetaldehyde | FL/FR |
| earthy indane | FR |
para- | ethyl acetophenone | FL/FR |
| ethyl ortho-anisate | FL/FR |
| geranyl phenyl acetate | FL/FR |
| hawthorn acetate | FR |
| hawthorn carbinol | FL/FR |
| heliotropin | FL/FR |
| heliotropyl acetate | FL/FR |
| heliotropyl acetone | FL/FR |
para- | methyl acetophenone | FL/FR |
| orris rhizome resinoid (iris pallida) | FL/FR |
| phenethyl salicylate | FL/FR |
(R)-2- | phenyl propyl alcohol | FL/FR |
| propiophenone | FL/FR |
iso | propyl anthranilate | FL/FR |
| tuberose absolute (from concrete) | FL/FR |
| tuberose absolute (from pommade) | FL/FR |
| tuberose acetate | FR |
| wallflower absolute | FR |
fruity |
para- | anisyl methyl ketone | FL/FR |
| benzyl methyl ether | FL/FR |
| berry hexanoate | FR |
| diethyl sebacate | FL/FR |
| diethyl succinate | FL/FR |
(E,E)- | ethyl sorbate | FL/FR |
| grapefruit acetal | FR |
green |
(E,Z)-3,6- | nonadien-1-yl acetate | FL/FR |
3,6- | nonadien-1-yl acetate | FL/FR |
| tiglaldehyde | FL/FR |
herbal |
| acorn acetate | FR |
| floral nitrile | FR |
| tricyclodecenyl isobutyrate | FR |
licorice |
(E)- | anethol | FL/FR |
| clausena anisata leaf oil | |
melon |
| melon heptenal | FL/FR |
minty |
bitter | fennel flower oil lithuania | |
bitter | fennel seed oil lithuania | CS |
naphthyl |
para- | methyl anisole | FL/FR |
beta- | naphthyl methyl ether | FL/FR |
phenolic |
| anisole | FL/FR |
powdery |
para- | anisyl alcohol | FL/FR |
smoky |
| propyl paraben | CS |
spicy |
| croton eluteria bark oil | FL/FR |
sweet |
| vanilla oleoresin bali | FL/FR |
terpenic |
| angelica seed oil | FL/FR |
vanilla |
| ethyl vanillin isobutyrate | FL/FR |
| vanillin | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
woody |
| cyperus root oil (cyperus rotundus) | FR |
| patchouli ethanone | FR |
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For Flavor |
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No flavor group found for these |
| amyl furoate | FL/FR |
(Z)- | anethol | |
para- | anisyl acetaldehyde | FL/FR |
| clausena anisata leaf oil | |
| dehydro-ar-ionene | |
para- | ethyl acetophenone | FL/FR |
4- | ethyl anisole | FL |
| ethyl ortho-anisate | FL/FR |
bitter | fennel flower oil lithuania | |
| geranyl benzoate | FL/FR |
(R)-2- | phenyl propyl alcohol | FL/FR |
| prenyl benzoate | FL/FR |
iso | propyl anthranilate | FL/FR |
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4'- | hydroxyacetophenone | FL |
amber |
| angelica seed oil | FL/FR |
animal |
para- | cresyl caprylate | FL/FR |
anise |
(E)- | anethol | FL/FR |
| anise oleoresin | FL/FR |
| anise seed oil | FL/FR |
star | anise seed oil china | FL/FR |
| anise seed oil colombia | FL/FR |
star | anise seed oil terpeneless | FL/FR |
| ethyl para-anisate | FL/FR |
sweet | fennel absolute | FL/FR |
sweet | fennel oleoresin | FL/FR |
sweet | fennel seed oil | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | anisaldehyde | FL/FR |
para- | anisyl phenyl acetate | FL/FR |
aromatic |
| anisole | FL/FR |
balsamic |
| phenethyl cinnamate | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
| raspberry ketone methyl ether | FL/FR |
cherry |
| heliotropin | FL/FR |
cocoa |
| cocoa distillates | FL |
creamy |
para- | anisaldehyde | FL/FR |
para- | methyl acetophenone | FL/FR |
fatty |
2,4- | decadien-1-ol | FL/FR |
(E,E)-2,4- | decadien-1-ol | FL/FR |
floral |
| geranyl phenyl acetate | FL/FR |
| heliotropyl acetate | FL/FR |
| orris rhizome resinoid (iris pallida) | FL/FR |
| tuberose absolute (from concrete) | FL/FR |
| tuberose absolute (from pommade) | FL/FR |
fruity |
para- | anisyl alcohol | FL/FR |
| benzyl methyl ether | FL/FR |
| boronia absolute | FL/FR |
| diethyl sebacate | FL/FR |
| diethyl succinate | FL/FR |
(E,E)- | ethyl sorbate | FL/FR |
| propiophenone | FL/FR |
| tiglaldehyde | FL/FR |
green |
| cinnamyl alcohol | FL/FR |
| cuminyl acetaldehyde | FL/FR |
| melon heptenal | FL/FR |
(E,Z)-3,6- | nonadien-1-yl acetate | FL/FR |
3,6- | nonadien-1-yl acetate | FL/FR |
herbal |
| dihydroanethol | FL/FR |
| ocimum basilicum herb oil | FL/FR |
| ocimum basilicum leaf oil america | FL/FR |
licorice |
2- | butyl-3-methyl pyrazine | FL |
medicinal, |
| phenethyl salicylate | FL/FR |
naphthyl |
para- | methyl anisole | FL/FR |
beta- | naphthyl methyl ether | FL/FR |
powdery |
ortho- | acetanisole | FL/FR |
| acetophenone | FL/FR |
| powdery ketone | FL |
rummy |
| vanillyl ethyl ether | FL/FR |
spicy |
para- | anisyl methyl ketone | FL/FR |
| croton eluteria bark oil | FL/FR |
| hawthorn carbinol | FL/FR |
4- | methyl biphenyl | FL |
sulfurous |
O- | ethyl S-1-methoxyhexan-3-yl carbonothioate | FL |
sweet |
| vanilla oleoresin bali | FL/FR |
tarragon |
| sassafras acetate | FL/FR |
vanilla |
| ethyl vanillin isobutyrate | FL/FR |
| vanillin | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
p- | anisic acid methyl ester | para- | anisic acid methyl ester | p- | anisic acid, methyl ester | | benzoic acid, 4-methoxy-, methyl ester | | menthyll anisate | 4- | methoxybenzoic acid methyl ester | para- | methoxybenzoic acid methyl ester | | methyl 4-methoxybenzoate | | methyl anisate | nat. | methyl anisate | | methyl anisate natural | | methyl p-anisate | | methyl p-methoxy benzoate | | methyl p-methoxybenzoate | | methyl para-methoxybenzoate | | methyl-4-methoxybenzoate |
Articles:
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