dextro,laevo-menthol
DL-menthol
 
Notes:
Found in many essential oils Menthol is an organic compound made synthetically or obtained from peppermint or other mint oils. Natural menthol exists as one pure stereoisomer, nearly always the (1R,2S,5R) form ((-)-menthol). There are 8 possible stereoisomers. (Wikipedia)
  • Berjé
    • Berje Inc.
      Where the world comes to its senses
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
      Email: For Information
      Email: For Sales
      Voice: 973-748-8980
      Fax: 973-680-9618
      Instagram
      Linkedin
      Flavor Ingredients
      Fragrance Ingredients
      Functional Ingredients
      Media
      Products List: View
      Product(s):
      Menthol Racemic
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
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      Product(s):
      89-78-1 DL-Menthol PURIFIED
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
      Email: Information
      US Voice: 845-341-2100
      US Fax: 845-341-2121
      Product(s):
      menthol, racemic USP
       
  • Glentham Life Sciences
  • Global Essence
    • Global Essence Inc.
      Preferred Partner
      Accommodate each customers unique needs.
      Global Essence was founded in 1993 as a two person operation servicing regional customers in the New York/ New Jersey area. In the twenty years since, it has grown into a multinational operation with offices in the US, UK, and Singapore. These offices allow Global to provide regional support to its customers worldwide. As the world continues become more connected, this approach positions Global to continue to offer the highest quality products and experience to all of its customers.
      Email: Info
      US Email: Info
      Voice: +44 (0) 1279 876666
      Fax: +44 (0)1279 876646
      US Voice: 001 732 677 1100
      US Fax: 001 732 677 1107
      Blog
      Press Release
      News
      Product(s):
      Menthol Block
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
      Email: Info
      Voice: 34 93 379 38 49
      Fax: 34 93 370 65 04
      Linkedin
      Product(s):
      MENTHOL LIQUID SYNTH.
      MENTHOL RACEMIC SYNTH.
       
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
      Email: Contact Us:
      US Email: Dean Matienzo
      Email: Sales
      US Email: Dean Matienzo - Sales Manager
      Voice: +44 1993 843081
      Fax: +44 1993 841261
      US Voice: +1 973 886 3778
      US Fax: +1 973 346 1106
      Linkedin
      Website
      Global Distribution
      Product(s):
      Menthol Crystals
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      13-12501 DL-MENTHOL USP (RACEMIC) SYNTHETIC
       
  • Sigma-Aldrich
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
      Email: Info
      Email: Sales
      Voice: +44 (0) 1284 704076
      Fax: +44 (0) 1284 760819
      Twitter
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      News
      Product(s):
      MENTHOL RACEMIC
       
  • Symrise
    • Symrise AG
      Always Insiring More
      Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.
      We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success.
      US Email: Life Essentials
      Email: Aroma Molecules
      Voice: +49 5531 90 0
      Twitter
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      Newsroom
      RSS Feed
      Product(s):
      600163 Menthol rac.

      Useful in: mint.
       
      107643 Menthol Rac. PH (German Origin)
      131391 Menthol RCP
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
      Facebook
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      Product(s):
      M0321 (±)-Menthol >98.0%(GC)
       
  • The Lermond Company
    • The Lermond Company
      Your Sourcing Resource
      The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.
      The Lermond Company is a women-owned distributor of raw materials primarily servicing the flavor and fragrance industry. For three generations, members of the Lermond family have been integral sourcing partners for the North American flavor and fragrance industry. We supply high quality essential oils, aroma chemicals, absolutes, concretes, resinoids and floral waters from around the world to the global industry.
      Email: Info
      Email: Tara
      Email: Erica
      Voice: 201-896-3300
      Fax: 201-623-2910
      Facebook
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      Linkedin
      Product(s):
      40558 MENTHOL, RACEMIC
       
  • R C Treatt & Co Ltd
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
      US Fax: +1 863 668 3388
      Twitter
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      News
      Product(s):
      Menthol
       
  • Ernesto Ventós
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas
CAS Number: 89-78-1Picture of molecule3D/inchi
Other(deleted CASRN): 15356-70-4
ECHA EINECS - REACH Pre-Reg: 201-939-0
FDA UNII: YS08XHA860
Nikkaji Web: J2.129F
Beilstein Number: 3194263
MDL: MFCD00001484
CoE Number: 63
XlogP3-AA: 3.00 (est)
Molecular Weight: 156.26860000
Formula: C10 H20 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
FR DOC # 2011-635 Menthol Report Subcommittee of the Tobacco Products Scientific Advisory Committee; Notice of Meeting Pages 2397 - 2398 View - petition PDF
JECFA Food Flavoring: 427  menthol
DG SANTE Food Flavourings: 02.015  menthol
FEMA Number: 2665 menthol
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):89-78-1 ; MENTHOL
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless crystalline fused (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: Yes
Melting Point: 34.00 to  36.00 °C. @ 760.00 mm Hg
Boiling Point: 212.00 to  216.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.032000 mmHg @ 25.00 °C. (est)
Flash Point: 200.00 °F. TCC ( 93.33 °C. )
logP (o/w): 3.400
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 paraffin oil
 water, 434.5 mg/L @ 25 °C (est)
 water, 456 mg/L @ 25 °C (exp)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: mentholic
 
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 
Substantivity: 32 hour(s) at 100.00 %
 
 peppermint  cooling  woody  
Odor Description:
at 10.00 % in dipropylene glycol. 
peppermint cool woody
 
 
Flavor Type: cooling
 
 cooling  mentholic  minty  
Taste Description:
cooling mentholic minty
 
Odor and/or flavor descriptions from others (if found).
 
Symrise
Menthol rac.
Odor Description: minty-fresh
Taste Description: minty-cooling
Useful in: mint.
 
Blue Pacific Flavors
Menthol
Odor Description: peppermint cool woody
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Menthol 98%
Aromatic and Allied Chemicals
Liquid Menthol
Arora Aromatics
Natural Menthol Powder / Melted
Aurochemicals
MENTHOL CRYSTALS, Natural
Berjé
Menthol Racemic
Media
Blue Pacific Flavors
Menthol
Odor: peppermint cool woody
BOC Sciences
For experimental / research use only.
DL-Menthol PURIFIED
EMD Millipore
For experimental / research use only.
DL-Menthol
Ernesto Ventós
MENTHOL RACEMIC, SYMRISE
Odor: MINTY, FRESH
Ernesto Ventós
MENTHOL-DL BASF
Odor: MINTY, FRESH
Flavor: MINTY, COOLING
Ernesto Ventós
MENTHOL, LIQUID
Fleurchem
menthol, racemic USP
Foodchem International
Menthol Crystal
Glentham Life Sciences
DL-Menthol
Global Essence
Menthol Block
Indis NV
For experimental / research use only.
Menthol Crystal
K.L. Koh Enterprise
MENTHOL
Lluch Essence
MENTHOL LIQUID SYNTH.
Lluch Essence
MENTHOL RACEMIC SYNTH.
OQEMA
Menthol Crystals
Pangaea Sciences
Menthol USP
Penta International
DL-MENTHOL USP (RACEMIC) SYNTHETIC
Prinova
Menthol
R C Treatt & Co Ltd
Menthol
Reincke & Fichtner
DL-Menthol
Santa Cruz Biotechnology
For experimental / research use only.
(±)-Menthol
Shaanxi Y-Herb Biotechnology
Natural Flavour Essence Herbal Extract Powder 99.5% Mint L - Menthol Crystal
Sigma-Aldrich
DL-Menthol, ≥95%, FCC, FG
Odor: minty; woody; camphoraceous
Certified Food Grade Products
Silverline Chemicals
Liquid Menthol
SRS Aromatics
MENTHOL RACEMIC
Symrise
Menthol Rac. PH (German Origin)
Symrise
Menthol rac.
Odor: minty-fresh
Flavor: minty-cooling
Useful in: mint.
Symrise
Menthol RCP
Odor: Mint, Fresh
TCI AMERICA
For experimental / research use only.
(±)-Menthol >98.0%(GC)
The Lermond Company
MENTHOL, RACEMIC
Vigon International
Menthol Crystals Natural FCC
Vigon International
Menthol Liquid
Vigon International
Menthol Racemic
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 37/38 - Irritating to respiratory system and skin.
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
GHS Label elements, including precautionary statements
 
Pictogramcorrosion.jpgexclamation-mark.jpg
 
Signal word Danger
Hazard statement(s)
H315 - Causes skin irritation
H318 - Causes serious eye damage
H335 - May cause respiratory irritation
Precautionary statement(s)
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 - Wash skin thouroughly after handling.
P271 - Use only outdoors or in a well-ventilated area.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 - IF ON SKIN: wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310 - Immediately call a POISON CENTER or doctor/physician.
P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention.
P362 - Take off contaminated clothing and wash before reuse.
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
gavage-mouse LD50  [sex: M] 2652 mg/kg
(Food & Drug Research LaboratoriesInc., 1975a)

gavage-mouse LD50  [sex: M] 4384 mg/kg
(Food & Drug Research Laboratories Inc, 1975a)

gavage-mouse LD50  3100 mg/kg
(Wokes, 1932)

gavage-rat LD50  [sex: M,F] 3180 mg/kg
(Jenner et al., 1964)

intravenous-cat LDLo  37 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 63, Pg. 43, 1939.

oral-cat LDLo  1500 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.

intraperitoneal-mouse LDLo  1800 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 63, Pg. 43, 1939.

intramuscular-rat LD50  10000 mg/kg
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 222, Pg. 244, 1954.

oral-rat LD50  3180 mg/kg
BEHAVIORAL: ATAXIA
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

intraperitoneal-rat LDLo  1500 mg/kg
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: SLEEP BEHAVIORAL: MUSCLE WEAKNESS
Annales Pharmaceutiques Francaises. Vol. 10, Pg. 481, 1952.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
maximum skin levels for fine fragrances:
  0.5200 %  and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2004)
Recommendation for dextro,laevo-menthol usage levels up to:
  8.0000 % in the fragrance concentrate.
use level in formulae for use in cosmetics:
  0.2900 %
Dermal Systemic Exposure in Cosmetic Products:
 0.0074 mg/kg/day (IFRA, 2004)
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 16000.00 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -130.00000
beverages(nonalcoholic): -35.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -1100.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -68.00000
fruit ices: -68.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -400.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of alicyclic substances used as flavor ingredients. View pdf
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 18 (FGE.18): Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters from chemical group 6
View page or View pdf
Flavouring Group Evaluation 51, (FGE.51)[1] - Consideration of alicyclic ketones and secondary alcohols and related esters evaluated by JECFA (59th meeting) and structurally related to alicyclic ketones, secondary alcohols and related esters evaluated by EFSA in FGE.09 (2004) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 14, Revision 1 (FGE.14Rev1): Phenethyl alcohol, aldehyde, acetals, carboxylic acid and related esters from chemical group 15 and 22 [1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 18, Revision 1 (FGE. 18 Rev1)[1] : Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters from chemical groups 6 and 8
View page or View pdf
Flavouring Group Evaluation 43: Thujyl alcohol from chemical group 8
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 90 (FGE.90): Consideration of Aliphatic, acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances evaluated by JECFA (68th meeting)FGE.18Rev1 (2009)
View page or View pdf
Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf
Safety and efficacy of secondary alicyclic saturated and unsaturated alcohols, ketones, ketals and esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols from chemical group 8 when used as flavourings for all animal species
View page or View pdf
EPI System: View
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 89-78-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 1254
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 5-methyl-2-propan-2-ylcyclohexan-1-ol
Chemidplus: 0000089781
EPA/NOAA CAMEO: hazardous materials
RTECS: OT0350000 for cas# 89-78-1
Synonyms   Articles   Notes   Search   Top
References:
Leffingwell: Chirality or Article
 5-methyl-2-propan-2-ylcyclohexan-1-ol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 89-78-1
Pubchem (cid): 1254
Pubchem (sid): 134972992
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D04849
HMDB (The Human Metabolome Database): HMDB35765
FooDB: FDB015462
Export Tariff Code: 2906.11.0000
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•some synthetic menthols are not chemical individuals but...mixtures of various isomers...these are designated...l-menthol, dl-menthol, l-isomenthol, d-isomenthol, dl-isomenthol, l-neomenthol, d-neomenthol, l-neoisomenthol, d-neoisomenthol and dl-neoisomenthol. •when mixed with about equal wt of camphor, chloral hydrate, phenol, or thymol, menthol forms "eutectic" mixt liquifying @ room temp. •menthol, usp drug marketed under generic name. •grades: technical; usp; fcc •synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%. synthetic menthol is also commercially available as the racemic mixture •present in cigarettes and pipe tobacco (0.1-0.45%) shaving creams, pre- and aftershave lotions (0.2-0.3%); toothpastes (0.5%); mouthwashes (1-2%); chewing gums (0.5%); cough drops (0.1%); refreshing towels (1%); rubbing alcohol (1-1.2%); and shampoos (2-0.5%) •mentholatum deep heating rub contains 5.9% menthol; mentholatum ointment, 1.35%; mentholatum deep heating lotion, 6%
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
anise
anise
 anise seed oil colombiaFL/FR
anisic
 dihydroanetholFL/FR
balsamic
 amyris wood oilFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
isobornyl acetateFL/FR
 clover nitrileFR
dextro-fenchoneFL/FR
camphoreous
 camphor tree bark oilFL/FR
beta-homocyclocitralFL/FR
fatty
 decanolFL/FR
floral
isoamyl salicylateFL/FR
 bois de rose oil brazilFL/FR
 cyclohexyl ethyl alcoholFL/FR
 geranium oil bourbonFL/FR
 heliotropyl diethyl acetalFR
alpha-hexyl cinnamaldehydeFL/FR
 ho leaf oilFR
 hyacinth etherFR
 linaloolFL/FR
laevo-linaloolFL/FR
 linalool oxideFL/FR
 methyl dihydrojasmonateFL/FR
 nerolFL/FR
 ocean propanalFL/FR
fruity
 menthyl isovalerateFL/FR
herbal
1,4-cineoleFL/FR
 eucalyptus globulus oilFL/FR
6-hydroxydihydrotheaspirane (mixture of isomers)FL/FR
abrialis lavandin oilFL/FR
 lavender absolute bulgariaFL/FR
spike lavender oilFL/FR
 linalyl acetateFL/FR
 nopyl acetateFR
 rosemary oil spainFL/FR
mentholic
 cornmint oilFL/FR
 cornmint oil chinaFL/FR
 cornmint oil indiaFL/FR
 cornmint oil terpenelessFL/FR
dextro-neomentholFL/FR
neoisomentholFL/FR
(±)-mentholFL/FR
dextro,laevo-neomentholFL/FR
laevo-mentholFL/FR
(±)-isomenthoneFL/FR
(+)-menthoneFL/FR
 menthyl acetateFL/FR
laevo-menthyl acetateFL/FR
 menthyl acetate racemicFL/FR
 peppermint cyclohexanoneFL/FR
dextro-piperitoneFL/FR
isopulegyl acetateFL/FR
minty
laevo-carvoneFL/FR
 cornmint oil japanFL/FR
 cornmint oil terpenesFR
dextro-dihydrocarvoneFL/FR
 mentha piperita extractFL/FR
 mentha piperita flower/leaf/stem extractFL/FR
 mentha piperita flower/leaf/stem waterFR
 mentha piperita herb extract americaFR
 mentha piperita leaf waterFR
 mentha piperita tinctureFL/FR
homomentholFL/FR
(-)-menthoneFL/FR
(±)-menthoneFL/FR
laevo-menthyl lactateFL/FR
2-methyl cyclohexanoneFL/FR
 methyl salicylateFL/FR
 pennyroyal oilFL/FR
 peppermint absoluteFL/FR
 peppermint distillatesFL/FR
 peppermint fragranceFR
 peppermint leafCS
 peppermint oilFL/FR
 peppermint oil americaFL/FR
 peppermint oil brazilFL/FR
 peppermint oil chinaFL/FR
 peppermint oil CO2 extractFL/FR
 peppermint oil dementholizedFL/FR
 peppermint oil englandFL/FR
 peppermint oil franceFL/FR
 peppermint oil hungaryFL/FR
 peppermint oil idahoFL/FR
 peppermint oil indiaFL/FR
 peppermint oil mongoliaFL/FR
 peppermint oil montanaFL/FR
 peppermint oil moroccoFL/FR
 peppermint oil russiaFL/FR
 peppermint oil special fractionsFL/FR
 peppermint oil tasmaniaFL/FR
 peppermint oil terpenelessFL/FR
 peppermint oil terpenesFR
 peppermint oil willametteFL/FR
 peppermint oil yakimaFL/FR
 peppermint waterFL/FR
laevo-piperitoneFL/FR
isopulegolFL/FR
(-)-isopulegolFL/FR
isopulegoneFL/FR
(R)-(+)-pulegoneFR
 spearmint oil americaFL/FR
 wintergreen oilFL/FR
 WS-23FL/FR
phenolic
 methyl benzoateFL/FR
powdery
para-anisyl alcoholFL/FR
spicy
 elettaria cardamomum seed oilFL/FR
 pepper tree berry oilFL/FR
 pimenta acris leaf oilFL/FR
alpha-terpineolFL/FR
waxy
 decyl acetateFL/FR
(Z)-woody amyleneFR
 
For Flavor
 
No flavor group found for these
(±)-N,N-dimethyl menthyl succinamideFL
neoisomentholFL/FR
dextro,laevo-neomentholFL/FR
3-laevo-menthoxy-2-methyl propane-1,2-diolFL
 menthyl acetate racemicFL/FR
2-methyl cyclohexanoneFL/FR
isopulegoneFL/FR
 menthyl methyl lactateFL
anise
 anise seed oil colombiaFL/FR
balsamic
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
camphoreous
 camphor tree bark oilFL/FR
6-hydroxydihydrotheaspirane (mixture of isomers)FL/FR
citrus
 linaloolFL/FR
laevo-linaloolFL/FR
 nerolFL/FR
alpha-terpineolFL/FR
cooling
1,4-cineoleFL/FR
beta-homocyclocitralFL/FR
dextro-fenchoneFL/FR
spike lavender oilFL/FR
isomentholFL
laevo-mentholFL/FR
 menthyl acetateFL/FR
laevo-menthyl lactateFL/FR
 peppermint oil americaFL/FR
floral
 bois de rose oil brazilFL/FR
 geranium oil bourbonFL/FR
 linalyl acetateFL/FR
 methyl dihydrojasmonateFL/FR
 ocean propanalFL/FR
fruity
para-anisyl alcoholFL/FR
 menthyl isovalerateFL/FR
green
isoamyl salicylateFL/FR
 cyclohexyl ethyl alcoholFL/FR
dextro-dihydrocarvoneFL/FR
 linalool oxideFL/FR
isophoroneFL
herbal
 dihydroanetholFL/FR
 eucalyptus globulus oilFL/FR
abrialis lavandin oilFL/FR
 lavender absolute bulgariaFL/FR
 rosemary oil spainFL/FR
mentholic
 cornmint oilFL/FR
 cornmint oil terpenelessFL/FR
dextro-neomentholFL/FR
(±)-mentholFL/FR
(+)-menthoneFL/FR
 peppermint cyclohexanoneFL/FR
minty
laevo-carvoneFL/FR
 cherry menthol flavorFL
 cornmint oil chinaFL/FR
 cornmint oil indiaFL/FR
 cornmint oil japanFL/FR
 mentha piperita extractFL/FR
 mentha piperita flower/leaf/stem extractFL/FR
 mentha piperita tinctureFL/FR
homomentholFL/FR
(±)-menthoneFL/FR
(±)-isomenthoneFL/FR
(-)-menthoneFL/FR
laevo-menthyl acetateFL/FR
 methyl salicylateFL/FR
 pennyroyal oilFL/FR
 peppermint absoluteFL/FR
 peppermint distillatesFL/FR
 peppermint flavorFL
 peppermint oilFL/FR
 peppermint oil brazilFL/FR
 peppermint oil chinaFL/FR
 peppermint oil CO2 extractFL/FR
 peppermint oil dementholizedFL/FR
 peppermint oil englandFL/FR
 peppermint oil franceFL/FR
 peppermint oil hungaryFL/FR
 peppermint oil idahoFL/FR
 peppermint oil indiaFL/FR
 peppermint oil mongoliaFL/FR
 peppermint oil montanaFL/FR
 peppermint oil moroccoFL/FR
 peppermint oil russiaFL/FR
 peppermint oil special fractionsFL/FR
 peppermint oil tasmaniaFL/FR
 peppermint oil terpenelessFL/FR
 peppermint oil willametteFL/FR
 peppermint oil yakimaFL/FR
 peppermint waterFL/FR
laevo-piperitoneFL/FR
dextro-piperitoneFL/FR
(-)-isopulegolFL/FR
isopulegolFL/FR
 spearmint oil americaFL/FR
 wintergreen oilFL/FR
 WS-23FL/FR
phenolic
 methyl benzoateFL/FR
spicy
 elettaria cardamomum seed oilFL/FR
 pepper tree berry oilFL/FR
 pimenta acris leaf oilFL/FR
terpenic
para-menthatrieneFL
waxy
 decanolFL/FR
 decyl acetateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
woody
 amyris wood oilFL/FR
isobornyl acetateFL/FR
isopulegyl acetateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 betelFR
 citrusFR
 cream ice creamFL
 herbalFR
 mintFR
 pennyroyalFL/FR
 peppermintFR
 roseFR
 spearmintFR
 tobaccoFR
 wintergreenFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 peppermint
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 cyclohexanol, 5-methyl-2-(1-methylethyl)-
dextro,laevo-hexahydrothymol
DL-hexahydrothymol
dextro,laevo-menthacamphor
DL-menthacamphor
p-menthan-3-ol
para-menthan-3-ol
p-menthane-3-ol
para-menthane-3-ol
(±)-menthol
(±)-(1R*,3R*,4S*)-menthol
DL-menthol
 menthol crystals FCC natural
 menthol crystals natural
 menthol Liquid
 menthol rac.
 menthol rac. PH
 menthol racemic
 menthol RC
dextro,laevo-menthol synthetic USP/FCC
 menthol USP
DL-menthol USP (racemic) synthetic
 menthol, racemic USP
(1alpha,2beta,5alpha)-5-methyl-2-(1-methyl ethyl) cyclohexanol
(1R,2S,5R)-rel-5-methyl-2-(1-methyl ethyl) cyclohexanol
(1alpha,2beta,5alpha)-5-methyl-2-(1-methylethyl)cyclohexanol
(1R,2S,5R)-rel-5-methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
dextro,laevo-peppermint camphor
DL-peppermint camphor
4-isopropyl-1-methyl cyclohexan-3-ol
4-isopropyl-1-methylcyclohexan-3-ol
(±)-2-isopropyl-5-methylcyclohexanol
 tra-kill tracheal mite killer
Synonyms   Articles   Notes   Search   Top
Articles:
Info: Menthol
PubMed: Terpenes increase the partitioning and molecular dynamics of an amphipathic spin label in stratum corneum membranes.
PubMed: Investigation of factors affecting the adsorption of functional molecules onto gel silicas. 1. Flow microcalorimetry and infrared spectroscopy.
PubMed: Characterization of cytotoxic and genotoxic effects of different compounds in CHO K5 cells with the comet assay (single-cell gel electrophoresis assay).
PubMed: Factors affecting the resolution of dl-menthol by immobilized lipase-catalyzed esterification in organic solvent.
PubMed: Comparison of acid anhydrides with carboxylic acids in enantioselective enzymatic esterification of racemic menthol.
PubMed: Bioassay of dl-menthol for possible carcinogenicity.
PubMed: [Synthesis of DL-menthol].
PubMed: [On the assay of DL-menthol for contamination by DL-neomenthol. 2. Report on the menthol monography in a new German pharmacopoeia].
PubMed: Studies in detoxication: The use of the glucuronic acid detoxication mechanism of the rabbit for the resolution of dl-menthol.
PubMed: Studies in detoxication. II. (a) The conjugation of isomeric 3-menthanols with glucuronic acid and the asymmetric conjugation of dl-menthol and dl-isomenthol in the rabbit. (b) d-isoMenthylglucuronide, a new conjugated glucuronic acid.
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