Category: antioxidants and preservatives for fragrance and flavor
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| FDA/DG SANTE Petitions, Reviews, Notices: |
172.115 | Butylated Hydroxytoluene (BHT) View - review |
EU SANCO | Butylated hydroxytoluene (BHT) View - review |
JECFA Food Additive: | Butylated Hydroxytoluene |
GSFA Codex: | Butylated hydroxytoluene (321) |
DG SANTE Food Additives: | BHT |
DG SANTE Food Contact Materials: | BHT |
FEMA Number: | 2184 butylated hydroxytoluene |
FDA: | No longer provide for the use of these seven synthetic flavoring substances |
FDA Mainterm (SATF): | 128-37-0 ; BUTYLATED HYDROXYTOLUENE |
FDA Regulation: | FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products Sec. 137.350 Enriched rice.
FDA PART 166 -- MARGARINE Subpart B--Requirements for Specific Standardized Margarine Sec. 166.110 Margarine.
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart B--Food Preservatives Sec. 172.110 BHA.
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart B--Food Preservatives Sec. 172.115 BHT.
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart B--Food Preservatives Sec. 172.185 TBHQ.
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart G--Gums, Chewing Gum Bases and Related Substances Sec. 172.615 Chewing gum base.
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION Subpart D--Specific Usage Additives Sec. 173.340 Defoaming agents.
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.105 Adhesives.
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.125 Pressure-sensitive adhesives.
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart C--Substances for Use as Components of Coatings Sec. 175.300 Resinous and polymeric coatings.
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart C--Substances for Use as Components of Coatings Sec. 175.380 Xylene-formaldehyde resins condensed with 4,4'-isopropylidenediphenol-epichlorohydrin epoxy resins.
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart C--Substances for Use as Components of Coatings Sec. 175.390 Zinc-silicon dioxide matrix coatings.
FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.
FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.210 Defoaming agents used in the manufacture of paper and paperboard.
FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1010 Acrylic and modified acrylic plastics, semirigid and rigid.
FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1210 Closures with sealing gaskets for food containers.
FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1350 Ethylene-vinyl acetate copolymers.
FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2260 Filters, resin-bonded.
FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2600 Rubber articles intended for repeated use.
FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS Subpart C--Antioxidants and Stabilizers Sec. 178.2010 Antioxidants and/or stabilizers for polymers.
FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS Subpart D--Certain Adjuvants and Production Aids Sec. 178.3570 Lubricants with incidental food contact.
FDA PART 179 -- IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF FOOD Subpart C--Packaging Materials for Irradiated Foods Sec. 179.45 Packaging materials for use during the irradiation of prepackaged foods.
FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS Subpart B--Specific Prior-Sanctioned Food Ingredients Sec. 181.24 Antioxidants.
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE Subpart D--Chemical Preservatives Sec. 182.3173 Butylated hydroxytoluene.
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Physical Properties:
Appearance: | colorless crystals (est) |
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | Yes |
Melting Point: | 70.00 to 73.00 °C. @ 760.00 mm Hg
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Boiling Point: | 265.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 15.000000 mmHg @ 141.00 °C. |
Vapor Density: | 7.6 ( Air = 1 ) |
Flash Point: | > 200.00 °F. TCC ( > 93.33 °C. )
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logP (o/w): | 5.100 |
Soluble in: |
| alcohol | | water, 0.6 mg/L @ 25 °C (exp) |
Organoleptic Properties:
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Odor Type: phenolic |
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Odor Strength: | low |
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Substantivity: | 400 hour(s) at 20.00 % in dipropylene glycol |
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| phenolic camphoreous |
Odor Description: at 100.00 %. | mild phenolic camphor |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Anhui Haibei |
BHT
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Augustus Oils |
Butylated Hydroxytoluene
|
Services |
BOC Sciences |
For experimental / research use only. |
2,6-Di-tert-butyl-4-methylphenol >99.0%(GC)
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Charkit Chemical |
BUTYLATED HYDROXY TOLUENE NF/FCC BHT
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Charkit Chemical |
BUTYLATED HYDROXY TOLUENE
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Diffusions Aromatiques |
BHT
|
Eastman Chemical |
Eastman Tenox™ BHT Food-Grade Antioxidant, Kosher
|
ECSA Chemicals |
BUTYLHYDROXYTOLUENE BHT TECHN.
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ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
ECSA Chemicals |
BUTYLHYDROXYTOLUENE BHT
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EMD Millipore |
For experimental / research use only. |
2,6-Di-tert-butyl-4-methylphenol
|
Foodchem International |
Butylated Hydroxy Toluene
|
Glentham Life Sciences |
Butylated hydroxytoluene
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Global Essence |
Butylated Hydroxy Toluene
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Graham Chemical |
BHT
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HallStar |
BHT
Odor: characteristic Use: BHT (Butylated hydroxytoluene) is a white solid of melting point 70°C with mild characteristic odor. It is readily fat-soluble and sparingly water soluble and is used primarily an antioxidant additive, extending the shelf life of products with unsaturated (and especially polyunsaturated) fatty acid moieties. |
Indenta Group |
BHT
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Indis NV |
For experimental / research use only. |
BHT - Butylhydroxytoluene
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Kraft Chemical |
BHT
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Lluch Essence |
BHT
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M&U International |
BUTYLATED HYDROXY TOLUENE
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Moellhausen |
BHT
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OQEMA |
Butylated Hydroxy Toluene (BHT Tech./Feed)
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OQEMA |
Butylated Hydroxy Toluene (BHT Technical, Food & Feed grades all available)
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OQEMA |
Embanox BHT
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Pell Wall Perfumes |
BHT – anti-oxidant
Odor: odourless at the levels used in perfumes, slightly camphoraceous / phenolic in concentration Use: Arctander gives this description: “insoluble in water, soluble in alcohol and Propylene glycol. Soluble in most oils and essential oils at 0.05 to 1%
Used as an Antioxidant in foods, chemicals, perfume materials (natural and synthetic), etc., often in combination with Butyl hydroxy anisole (BHA) and Propyl gallale, Citric acid, etc. in Propylene glycol solution. |
Penta International |
BUTYLATED HYDROXY TOLUENE (BHT) NF GRADE POWDER (40 MESH)
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Penta International |
BUTYLATED HYDROXY TOLUENE (BHT) NF 80 MESH POWDER
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Penta International |
BUTYLATED HYDROXY TOLUENE (BHT) NF / FCC
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Penta International |
BUTYLATED HYDROXY TOLUENE TECHNICAL GRADE
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Penta International |
BUTYLATED HYDROXYTOLUENE (BHT) FCC GRADE
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Penta International |
BUTYLATED HYDROXYTOLUENE (BHT) NF EP GRADE
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Penta International |
BUTYLATED HYDROXYTOLUENE (BHT) NF GRADE POWDER (60 MESH)
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Penta International |
BUTYLATED HYDROXYTOLUENE (BHT) NF
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Penta International |
BUTYLATED HYDROXYTOLUENE NF EP GRADE POWDER (60 MESH)
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Penta International |
BUTYLATED HYDROXYTOLUENE NF EP GRADE POWDER MICRONIZED
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Penta International |
BUTYLATED HYDROXYTOLUENE NF EP GRADE POWDER (80 MESH)
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Prinova |
BHT
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R C Treatt & Co Ltd |
B.H.T.
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Reincke & Fichtner |
Butylated Hydroxytoluene
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Santa Cruz Biotechnology |
For experimental / research use only. |
butylated Hydroxytoluene >98%
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Sigma-Aldrich |
Butylated hydroxytoluene, ≥99%, FCC, FG
|
Certified Food Grade Products |
Silver Fern Chemical |
Butylated Hydroxytoluene (BHT)
Odor: characteristic Use: BHT is used as an antioxidant and can be a food additive. It is also found in some cosmetics, pharmaceuticals, rubbers, and is often used in the oil industry. |
Sinofi Food Ingredients |
Butylated Hydroxytoluene
Odor: characteristic Use: Antioxidants, Food Preservative, Oils and Fats, Chewing Gum, Potato Chip, Fried Food, Frozen Food, Dairy Products, Baking Food, Shortening, Margarine, Flavoring Agent, Packaging Material, Meat, Nutrient, Dietary Supplement, Cosmetics, Feed, Pharmaceutical, Plastic and Rubber, Lubricant. |
Sinoway Industrial |
For experimental / research use only. |
2,6-Di-tert-butyl-4-methylphenol
(99% up, powder) |
TCI AMERICA |
For experimental / research use only. |
2,6-Di-tert-butyl-p-cresol >99.0%(GC)
|
The John D. Walsh Company |
Butylated Hydroxy Toluene
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The Lermond Company |
BUTYLATED HYDROXY TOLUENE
|
United International |
BHT
|
Vigon International |
BHT (Butylated Hydroxy Toluene)
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WholeChem |
2,6 ? Di-tert Butyl-para-cresol
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Zhong Ya Chemical |
BHT (Butylated Hydroxy Toluene) Tech Grade
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 07 - Keep container tightly closed. S 22 - Do not breath dust. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Chronic aquatic toxicity (Category 1), H410
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GHS Label elements, including precautionary statements |
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Pictogram | |
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Signal word | Warning |
Hazard statement(s) |
H410 - Very toxic to aquatic life with long lasting effects
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Precautionary statement(s) |
P273 - Avoid release to the environment. P391 - Collect spillage. Hazardous to the aquatic environment P501 - Dispose of contents/ container to an approved waste disposal plant.
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Oral/Parenteral Toxicity: |
oral-rat LD50 890 mg/kg Neoplasma. Vol. 24, Pg. 253, 1977.
intravenous-mouse LD50 180 mg/kg BEHAVIORAL: SLEEP Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980.
intraperitoneal-mouse LD50 138 mg/kg Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980.
oral-mouse LD50 650 mg/kg BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.
oral-guinea pig LD50 10700 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: TREMOR
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" AMA Archives of Industrial Health. Vol. 11, Pg. 93, 1955.
oral-cat LDLo 940 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION AMA Archives of Industrial Health. Vol. 11, Pg. 93, 1955.
intraperitoneal-mouse LD50 138 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BLOOD: HEMORRHAGE
LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA Toxicology and Applied Pharmacology. Vol. 61, Pg. 475, 1981.
oral-rabbit LDLo 2100 mg/kg BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" AMA Archives of Industrial Health. Vol. 11, Pg. 93, 1955.
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | antioxidants and preservatives for fragrance and flavor |
Recommendation for butylated hydroxytoluene usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | - |
beverages(nonalcoholic): | - | - |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
| antioxidants | |
| preservatives | |
Occurrence (nature, food, other): note
Synonyms:
| advastab 401 | | agidol | | alkofen BP | | annulex BHT | | antioxidant 264 | | antioxidant 29 | | antioxidant 30 | | antioxidant 4 | | antioxidant DBPC | | antioxidant KB | | antioxidant MPJ | | antioxidant T 501 | | antox QT | | antracine 8 | | antrancine 8 | | B.H.T. | | BHT | | BHT (butylated hydroxy toluene) tech grade | | BHT FCC/NF | 2,6-bis(tert- | butyl)-4-methylphenol | | catalin antioxydant 1 | | catalin CAO-3 | | chemanox 11 | (2,5- | cyclohexadiene-1,4-diylidene)-dimalononitrile | | dalpac | | deenax | 2,6- | di-(tert-butyl)-4-methylphenol | 2,6- | di-t-butyl-4-methylphenol | 2,6- | di-t-butyl-p-cresol | 2,6- | di-tert-butyl-1-hydroxy-4-methylbenzene | 2,6- | di-tert-butyl-4-cresol | 2,6- | di-tert-butyl-4-hydroxytoluene | 2,6- | di-tert-butyl-4-methyl phenol | 2,6- | di-tert-butyl-4-methylhydroxybenzene | 2,6- | di-tert-butyl-4-methylphenol | 2,6- | di-tert-butyl-p-cresol | 2,6- | di-tert-butyl-p-methylphenol | 2,6- | di-tert-butyl-para-cresol | 2,6- | di-tert-butylcresol | 2,6-bis(1,1- | dimethylethyl)-4-methylphenol | | embanox BHT | | hydagen DEO | butylated | hydroxy toluene | butylated | hydroxy toluene (BHT) N.F. grade powder (40 mesh) | 4- | hydroxy-3,5-di-tert-butyltoluene | 1- | hydroxy-4-methyl-2,6-di-tert-butylbenzene | butylated | hydroxytoluene (BHT) N.F. grade powder (60 mesh) | butylated | hydroxytoluene (BHT) FCC grade | butylated | hydroxytoluene (BHT) N.F. grade | butylated | hydroxytoluene (BHT) NF & EP grade | butylated | hydroxytoluene NF & EP grade powder (325 mesh) | butylated | hydroxytoluene NF & EP grade powder (60 mesh) | butylated | hydroxytoluene NF & EP grade powder (80 mesh) | | impruvol | | ional | | kerabit | 4- | methyl-2,6-di-t-butyl-phenol | 4- | methyl-2,6-ditertbutylphenol | 4- | methyl-2,6-tert-butylphenol | | nocrac 200 | | nonox TBC | | parabar | | paranox 441 | | tenox BHT food-grade antioxidant | | vianol |
Articles:
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