ketoisophorone
2,6,6-trimethylcyclohex-2-ene-1,4-dione
 
Notes:
Blends well with ozone and woody notes. Present in saffron (Crocus sativus) and tea; flavouring ingredient
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
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      4 Oxoisophorone
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
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      Product(s):
      10205 4-OxoisoPhorone
       
  • Berjé
    • Berje Inc.
      Where the world comes to its senses
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
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      Flavor Ingredients
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      Functional Ingredients
      Media
      Products List: View
      Product(s):
      ketoisophorone
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      1125-21-9 4-oxoisoPhorone
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
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      Product(s):
      A0123 4-oxoisoPhorone, Kosher
       
  • Pell Wall Perfumes
    • Pell Wall Perfumes
      Hand-made fragrances
      Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock.
      Pell Wall was founded by perfumer Chris Bartlett to provide exclusive hand-made fragrances to a select few people who love them. All our products are created using fine quality ingredients, many of which we also offer for sale to other perfumers and enthusiasts. Pell Wall make fragrances for men, for women and for the home.
      Email: Info
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      Voice: +44 (0) 20 3745 0887
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      Product(s):
      4-Oxoisophorone
      Unusual and rarely offered ingredient that gives the core odour character to the scent of Buddliea flowers. Deceptively strong. This material was featured at the World Perfumery Congress in 2016.
       
      4-Oxoisophorone 10%
      Unusual and rarely offered ingredient that gives the core odour character to the scent of Buddliea flowers. Deceptively strong, and here offered at 10% dilution in ethanol to make it more affordable.
       
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      20-80200 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE
       
  • Sigma-Aldrich
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
      Email: John Felton
      Email: Stephen Zhou (Sales)
      Voice: 0512-57995626
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      Product(s):
      A0131 4-oxoisoPhorone
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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      Inquiry
      Products List: View
      Product(s):
      W1772 2,6,6-Trimethyl Cyclohex-2-ene-1,4-dione
      W1772A 4-OXOISOPHORONE
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Voice: 1-800-423-8616
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      Product(s):
      K0034 4-Ketoisophorone >98.0%(GC)
       
  • Tianjin Danjun International
    • Tianjin Danjun International Trade Co., LTD.
      Quality Products
      We know the Chinese chemical market well.
      Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
      Email: Info
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      Voice: +86-15822601686
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      Product(s):
      A-022 4-Oxoisophorone
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
      Email: Info
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      Voice: +86-532-83893699
      Fax: +86-532-83893695
      Product(s):
      8008 2,6,6-Trimethyl-2-cyclohexene-1,4-dione
       
  • Vigon International
    • Vigon International
      Passion for Simplicity
      Manufacturer and supplier of high quality flavor and fragrance ingredients.
      The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities.
      US Email: Sales
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      Product(s):
      501364 Ketoisophorone Pure (Oxophorone-4)
       
  • WholeChem
    • WholeChem, LLC
      Connecting Innovators To the Building Blocks Of the Universe
      Custom manufacturer and distributor of specialty ingredients. We make global local.
      SQF-Certified Supplier
      We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing.
      Email: Info
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      Voice: +1 (262) 995.8668
      Certification
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      Products List: View
      Product(s):
      4-Oxoisophorone
       
Synonyms   Articles   Notes   Search
    Flavor Demo Formulas
CAS Number: 1125-21-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 214-406-2
FDA UNII: 72WY3KLB5R
Nikkaji Web: J94.748B
Beilstein Number: 2207030
MDL: MFCD00043119
CoE Number: 11200
XlogP3-AA: 1.00 (est)
Molecular Weight: 152.19304000
Formula: C9 H12 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 1857  2,6,6-trimethylcyclohex-2-ene-1,4-dione
DG SANTE Food Flavourings: 07.109  2,6,6-trimethylcyclohex-2-ene-1,4-dione
FEMA Number: 3421 2,6,6-trimethylcyclohex-2-ene-1,4-dione
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):1125-21-9 ; 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white to yellowish tan green solid or liquid (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 0.91800 @  25.00 °C.
Refractive Index: 1.49100 @  20.00 °C.
Melting Point: 23.00 to  28.00 °C. @ 760.00 mm Hg
Boiling Point: 92.00 to  94.00 °C. @ 11.00 mm Hg
Boiling Point: 222.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.158000 mmHg @ 25.00 °C. (est)
Flash Point: 205.00 °F. TCC ( 96.11 °C. )
logP (o/w): 0.994 (est)
Soluble in:
 alcohol
 water, slightly
 water, 1839 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: musty
 
 musty  woody  sweet  tea  tobacco  leafy  
Odor Description:
at 1.00 % in dipropylene glycol. 
musty woody sweet tea tobacco leaf
 
 musty  woody  sweet  tea  citrus  lemon  brown  
Odor Description:
Musty, woody, sweet, tea, citrus lemon with sI. brown nuances
Mosciano, Gerard P&F 15, No. 4, 59, (1990)
 
 
Flavor Type: citrus
 
 citrus  floral  musty  tea  green  sweet  fruity  
Taste Description:
at 40.00 ppm.  
Citrus, floral, musty, tea like with green sweet fruity nuances
Mosciano, Gerard P&F 15, No. 4, 59, (1990)
 
Odor and/or flavor descriptions from others (if found).
 
Sigma-Aldrich
4-Oxoisophorone, ≥98%, FG
Odor Description: musty; woody; sweet
Taste Description: citrus floral musty tea green sweet fruity
 
Pell Wall Perfumes
4-Oxoisophorone
Odor Description: Sweet, floral, honey, tea, woody, musty
Unusual and rarely offered ingredient that gives the core odour character to the scent of Buddliea flowers. Deceptively strong. This material was featured at the World Perfumery Congress in 2016.
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Apple Flavor & Fragrance
Oxoisophorone
Augustus Oils
4 Oxoisophorone
Services
Beijing Lys Chemicals
4-OxoisoPhorone
Berjé
ketoisophorone
Media
BOC Sciences
For experimental / research use only.
4-oxoisoPhorone
DeLong Chemicals America
2,6,6-Trimethylcyclohex-2-ene-1,4-dione
EMD Millipore
For experimental / research use only.
2,6,6-Trimethyl-2-cyclohexene-1,4-dione
M&U International
4-oxoisoPhorone, Kosher
Pell Wall Perfumes
4-Oxoisophorone 10%
Odor: Sweet, floral, honey, tea, woody, musty
Use: Unusual and rarely offered ingredient that gives the core odour character to the scent of Buddliea flowers. Deceptively strong, and here offered at 10% dilution in ethanol to make it more affordable.
Pell Wall Perfumes
4-Oxoisophorone
Odor: Sweet, floral, honey, tea, woody, musty
Use: Unusual and rarely offered ingredient that gives the core odour character to the scent of Buddliea flowers. Deceptively strong. This material was featured at the World Perfumery Congress in 2016.
Penta International
2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE
Shanghai Vigen Fine Chemical
4-Oxoisophorone
Sigma-Aldrich
4-Oxoisophorone, ≥98%, FG
Odor: musty; woody; sweet
Certified Food Grade Products
Sunaux International
4-oxoisoPhorone
Synerzine
2,6,6-Trimethyl Cyclohex-2-ene-1,4-dione
Synerzine
4-OXOISOPHORONE
TCI AMERICA
For experimental / research use only.
4-Ketoisophorone >98.0%(GC)
Tengzhou Xiang Yuan Aroma Chemicals
2,6,6-Trimethyl-2-cyclohexene-1,4-dione
Tianjin Danjun International
4-Oxoisophorone
United International
2,6,6-Trimethyl-2-cyclohexene-1,4-dione
Vigon International
Ketoisophorone Pure (Oxophorone-4)
Odor: FOOD-LIKE, FRUITY
WEN International
4-OXOISOPHORONE
Synthetic
WholeChem
4-Oxoisophorone
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 22 - Harmful if swallowed.
R 38 - Irritating to skin.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for ketoisophorone usage levels up to:
  2.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 50.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 1900 (μg/person/day)
Threshold of Concern:540 (μg/person/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 7
Click here to view publication 7
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): -1.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -5.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 7.0000035.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 2.0000010.00000
Edible ices, including sherbet and sorbet (03.0): 3.0000015.00000
Processed fruit (04.1): 2.0000010.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 4.0000020.00000
Chewing gum (05.0): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): --
Bakery wares (07.0): 5.0000025.00000
Meat and meat products, including poultry and game (08.0): 1.000005.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 1.000005.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 2.0000010.00000
Foodstuffs intended for particular nutritional uses (13.0): 3.0000015.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 2.0000010.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 4.0000020.00000
Ready-to-eat savouries (15.0): 5.0000025.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 2.0000010.00000
Synonyms   Articles   Notes   Search   Top
Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 213: alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.7 of FGE.19
View page or View pdf
List of apha, beta-Unsaturated Aldehydes and Ketones representative of FGE.19 substances for Genotoxicity Testing [1] - Statement of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 73, Revision 3 (FGE.73Rev3): Consideration of alicyclic alcohols, aldehydes, acids and related esters evaluated by JECFA (59th and 63rd meeting) structurally related to primary saturated or unsaturated alicyclic alcohols, aldehydes, acids and esters evaluated by EFSA in FGE.12Rev4 (2013)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 9, Revision 5 (FGE.09Rev5): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 87, Revision 2 (FGE.87Rev2): Consideration of bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated by EFSA in FGE.47Rev1 (2008)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 9, Revision 6 (FGE.09Rev6): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 213, Revision 2 (FGE.213Rev2): Consideration of genotoxic potential for a,ß-unsaturated alicyclic ketones and precursors from chemical subgroup 2.7 of FGE.19
View page or View pdf
Safety and efficacy of secondary aliphatic saturated or unsaturated alcohols, ketones, ketals and esters with a second secondary or tertiary oxygenated functional group belonging to chemical group 10 when used as flavourings for all animal species
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 1125-21-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 62374
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 2811
WGK Germany: 3
 2,6,6-trimethylcyclohex-2-ene-1,4-dione
Chemidplus: 0001125219
Synonyms   Articles   Notes   Search   Top
References:
 2,6,6-trimethylcyclohex-2-ene-1,4-dione
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 1125-21-9
Pubchem (cid): 62374
Pubchem (sid): 135020326
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): HMDB40216
FooDB: FDB019928
Export Tariff Code: 2914.29.5000
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
alcoholic
alcoholic
isopropyl alcoholFL/FR
aldehydic
 decanal (aldehyde C-10)FL/FR
amber
 amber naphthofuranFL/FR
 ambrette seed absoluteFL/FR
 cistus ladaniferus resinFR
animal
 methyl (E)-2-octenoateFL/FR
6-methyl quinolineFL/FR
balsamic
 amyl phenyl acetateFL/FR
laevo-borneolFL/FR
isobornyl formateFL/FR
 brachyleana hutchinsii wood oilFR
 guaiacyl phenyl acetateFL/FR
 guaiyl acetateFL/FR
 myrrh absoluteFL/FR
 opoponax resinoid replacerFR
 valerian rhizome absoluteFL/FR
cereal
 bran absoluteFR
citrus
 bergamot oilFL/FR
 bergamot oil bergaptene reduced italyFL/FR
 bergamot oil turkeyFL/FR
beta-bisabololFL/FR
2-dodecanoneFL/FR
2-ethyl-1-hexanolFL/FR
 petitgrain bergamot oilFL/FR
(±)-2,4,8-trimethyl-7-nonen-2-olFL/FR
10-undecen-1-olFL/FR
 verbena absolute franceFL/FR
coconut
(S)-gamma-hexalactone 
creamy
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
earthy
 geosminFL/FR
 geosminFL/FR
(Z)-linalool oxide (furanoid)FL/FR
fatty
(E)-2-octenalFL/FR
floral
 boronia butenalFR
 champaca absoluteFR
delta-damasconeFL/FR
 dimethyl benzyl carbinyl propionateFR
 geranyl formateFL/FR
 geranyl isobutyrateFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
beta-iononeFL/FR
(Z)-jasmoneFL/FR
 methyl dihydrojasmonateFL/FR
alpha-isomethyl ionone (90% min.)FL/FR
2-methyl naphthaleneFL/FR
 neroli oil bigardeFL/FR
 neryl isovalerateFL/FR
bitter orangeflower concrete moroccoFR
 petitgrain absolute moroccoFL/FR
 petitgrain bigarade oilFL/FR
 petitgrain oil moroccoFL/FR
 phenethyl isobutyrateFL/FR
 rose butanoateFL/FR
 tea acetateFR
 tetrahydrolinaloolFL/FR
 tetrahydrolinalyl acetateFR
 tobacco flower absoluteFR
fruity
alpha-amyl cinnamyl isovalerateFL/FR
isobutyl 2-butenoateFL/FR
isobutyl isovalerateFL/FR
 cyclohexanone diethyl acetalFL/FR
(E)-beta-damasconeFL/FR
beta-damasconeFL/FR
(Z)-beta-damasconeFL/FR
(R)-gamma-dodecalactoneFL/FR
 ethyl 3-hexenoateFL/FR
 ethyl 3-hydroxyhexanoateFL/FR
2-ethyl butyl 2-butenoate 
(E,E)-ethyl sorbateFL/FR
 geranyl acetoacetateFL/FR
 heptyl butyrateFL/FR
 menthyl isovalerateFL/FR
 neryl isobutyrateFL/FR
 prenyl acetateFL/FR
fungal
 methyl 2-furoateFL/FR
isogreen methanoindeneFR
 hexyl isobutyrateFL/FR
 magnolia flower oilFL/FR
 methyl R-3-acetoxyhexanoate 
 phenethyl tiglateFL/FR
 rose leaf absolute (rosa centifolia)FL/FR
hay
 beeswax absoluteFL/FR
 hay absoluteFR
 tobacco leaf absoluteFL/FR
 woodruff absoluteFR
herbal
6-acetoxydihydrotheaspiraneFL/FR
 anthemis nobilis flower oil romanFL/FR
 arnica flower oilFR
 clary sage absoluteFL/FR
 clary sage oil americaFL/FR
 clary sage oil franceFL/FR
 clary sage oil russiaFL/FR
delta-elemeneFL/FR
 herbal undecanoneFR
 matricaria chamomilla flower oilFL/FR
 methyl nicotinateFL/FR
 saffron indenoneFL/FR
 safranalFL/FR
 tea leaf absoluteFL/FR
 theaspiraneFL/FR
 yerba mate absoluteFL/FR
honey
 methyl phenyl acetateFL/FR
 phenyl acetic acidFL/FR
licorice
sweet basil oleoresinFL/FR
marine
 ozone propanalFR
isopulegyl acetateFL/FR
musk
 acetyl ethyl tetramethyl tetralin replacerFR
 musk decanolideFR
phenolic
2'-hydroxyacetophenoneFL/FR
popcorn
2-acetyl pyridineFL/FR
spicy
 cassia bark oleoresinFL/FR
(-)-cubenolFL/FR
N,N-diethyl octanamideFR
2,5-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate + 1,4-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetateFR
 ginger root absoluteFL/FR
 grains of paradise oilFL/FR
 methyl heptadienoneFL/FR
tea
 camellia oleifera leaf extractFL/FR
tobacco
para-cresyl isovalerateFL/FR
3-ethyl pyridineFL/FR
 methyl benzoxoleFL/FR
 tobacco concreteFR
(E,E/E,Z)-tobacco cyclohexenoneFL/FR
 veltonal (Bedoukian)FR
tonka
 deertongue absoluteFR
gamma-hexalactoneFL/FR
 mint lactoneFL/FR
 saffron resinoidFL/FR
 tonka undecanoneFR
tropical
 genet absoluteFL/FR
vanilla
 propenyl guaetholFL/FR
woody
 agarwood oil (aetoxylon sympetalum)FR
 amber decatrieneFR
 cabreuva wood oilFR
alpha-cedrene epoxideFR
 cedrol methyl etherFR
 cyperus root oil (cyperus rotundus)FR
 guaiacwood oil 20% in gurjun balsam oilFR
(-)-guaiolFR
 gurjun balsam oilFR
 homalomena rubescens root oilFR
isolongifolene ketoneFR
para-menth-3-en-1-olFL/FR
 patchouli hexanolFR
 sandalwood oil CO2 extractFL/FR
 spikenard oil CO2 extractFL/FR
 timber propanolFR
 tobacarol (IFF)FR
 tobacco noneneFR
 woody dioxolaneFR
 woody etherFR
 
For Flavor
 
No flavor group found for these
6-acetoxydihydrotheaspiraneFL/FR
 amyl phenyl acetateFL/FR
 cyclohexanone diethyl acetalFL/FR
(R)-gamma-dodecalactoneFL/FR
delta-elemeneFL/FR
2-ethyl butyl 2-butenoate 
 fig leaf absoluteFL
 geosminFL/FR
 grains of paradise oilFL/FR
 guaiyl acetateFL/FR
(S)-gamma-hexalactone 
(Z)-linalool oxide (furanoid)FL/FR
 magnolia flower oilFL/FR
para-menth-3-en-1-olFL/FR
 methyl nicotinateFL/FR
2-propyl pyridineFL
 spikenard oil CO2 extractFL/FR
10-undecen-1-olFL/FR
beta-damasconeFL/FR
alcoholic
isopropyl alcoholFL/FR
amber
 amber naphthofuranFL/FR
animal
6-methyl quinolineFL/FR
balsamic
 myrrh absoluteFL/FR
brown
 beeswax absoluteFL/FR
camphoreous
laevo-borneolFL/FR
caramellic
3-ethyl pyridineFL/FR
 methyl 2-furoateFL/FR
citrus
 bergamot flavorFL
 bergamot oilFL/FR
 bergamot oil bergaptene reduced italyFL/FR
 bergamot oil turkeyFL/FR
beta-bisabololFL/FR
 petitgrain bergamot oilFL/FR
 petitgrain bigarade oilFL/FR
 petitgrain oil moroccoFL/FR
(±)-2,4,8-trimethyl-7-nonen-2-olFL/FR
 verbena absolute franceFL/FR
coffee
2,4-dimethyl thiazoleFL
cooling
isomentholFL
 theaspiraneFL/FR
corn
2-acetyl pyridineFL/FR
creamy
gamma-hexalactoneFL/FR
 mint lactoneFL/FR
earthy
 geosminFL/FR
fatty
2-dodecanoneFL/FR
2-ethyl-1-hexanolFL/FR
(E)-2-octenalFL/FR
floral
 geranyl isobutyrateFL/FR
 methyl dihydrojasmonateFL/FR
alpha-isomethyl ionone (90% min.)FL/FR
 methyl phenyl acetateFL/FR
 neroli oil bigardeFL/FR
 petitgrain absolute moroccoFL/FR
 phenyl acetic acidFL/FR
 tetrahydrolinaloolFL/FR
fruity
alpha-amyl cinnamyl isovalerateFL/FR
fuji apple flavorFL
(E)-beta-damasconeFL/FR
(Z)-beta-damasconeFL/FR
 ethyl 3-hexenoateFL/FR
 ethyl 3-hydroxyhexanoateFL/FR
 ethyl 3-oxohexanoateFL
(E,E)-ethyl sorbateFL/FR
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
 menthyl isovalerateFL/FR
 methyl (E)-2-octenoateFL/FR
 neryl isobutyrateFL/FR
 neryl isovalerateFL/FR
 prenyl acetateFL/FR
 rose butanoateFL/FR
 valerian rhizome absoluteFL/FR
grassy
 tobacco leaf absoluteFL/FR
green
isobutyl 2-butenoateFL/FR
isobutyl isovalerateFL/FR
 cucumber distillatesFL
 cucumber flavorFL
 geranyl formateFL/FR
(E)-2-heptenalFL
 heptyl butyrateFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
 hexyl isobutyrateFL/FR
 methyl heptadienoneFL/FR
 methyl R-3-acetoxyhexanoate 
 phenethyl tiglateFL/FR
isophoroneFL
 rose leaf absolute (rosa centifolia)FL/FR
hay
 genet absoluteFL/FR
herbal
 anthemis nobilis flower oil romanFL/FR
 clary sage absoluteFL/FR
 clary sage oil americaFL/FR
 clary sage oil franceFL/FR
 clary sage oil russiaFL/FR
 matricaria chamomilla flower oilFL/FR
 saffron indenoneFL/FR
 yerba mate absoluteFL/FR
honey
 phenethyl isobutyrateFL/FR
licorice
sweet basil oleoresinFL/FR
mushroom
 methional diethyl acetalFL
musty
 geranyl acetoacetateFL/FR
naphthyl
2'-hydroxyacetophenoneFL/FR
nutty
 methyl benzoxoleFL/FR
(E,E/E,Z)-tobacco cyclohexenoneFL/FR
oily
2-methyl naphthaleneFL/FR
phenolic
para-cresyl isovalerateFL/FR
 guaiacyl phenyl acetateFL/FR
smoky
dextro-xyloseFL
spicy
 cassia bark oleoresinFL/FR
(-)-cubenolFL/FR
 ginger root absoluteFL/FR
 paprika oleoresinFL
sweet
 acetone alcoholFL
 saffron resinoidFL/FR
tea
 camellia oleifera leaf extractFL/FR
 tea leaf absoluteFL/FR
vanilla
 propenyl guaetholFL/FR
waxy
 decanal (aldehyde C-10)FL/FR
woody
 ambrette seed absoluteFL/FR
isobornyl formateFL/FR
delta-damasconeFL/FR
beta-iononeFL/FR
(Z)-jasmoneFL/FR
isopulegyl acetateFL/FR
 safranalFL/FR
 sandalwood oil CO2 extractFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 amberFR
 balsamFR
 cherryFR
 citrusFR
 honeyFR
 molassesFL
 orientalFR
 ozone 
 patchouliFR
 raspberryFR
 teaFL
 tobaccoFR
 woodyFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 champaca concrete @ 0.05%
Data  GC  Search Trop  Picture
 clover yellow sweet clover roasted
Search Trop  Picture
 honey - up to 8 mg/kg
Search  PMC Picture
 lemon balm
Search Trop  Picture
 lettuce lamb's lettuce
Search Trop  Picture
 saffron
Search Trop  Picture
 saffron
Search Trop  Picture
 shrimp cooked shrimp
Search  PMC Picture
 tea - up to 9 mg/kg
Search Trop  Picture
 tea black tea
Search Trop  Picture
 tea green tea
Search Trop  Picture
 tea rooibos tea
Search Trop  Picture
 tobacco smoke
Search  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 cetotabac
 cyclohex-2-ene-1,4-dione, 2,6,6-trimethyl-
2-cyclohexene-1,4-dione, 2,6,6-trimethyl-
oxopholone
4-ketoisophorone
4-oxo-alpha-isophorone
4-oxoisophorone
6-oxoisophorone
keto-isophorone
ketoisophorone
oxoisophorone
ketoisophorone pure
2,6,6-trimethyl cyclohex-2-ene-1,4-dione
2,2,6-trimethyl cyclohex-5-en-1,4-dione
2,6,6-trimethyl-2-cyclohexene-1,4-dione
3,5,5-trimethyl-2-cyclohexene-1,4-dione
2,2,6-trimethyl-5-cyclohexen-1,4-dione
2,6,6-trimethyl-cyclohex-2-ene-1,4-dione
3,5,5-trimethyl-cyclohex-2-ene-1,4-dione
2,2,6-trimethyl-cyclohex-5-en-1,4-dione
2,6,6-trimethylcyclohex-2-ene-1,4-dione
2,2,6-trimethylcyclohex-5-en-1,4-dione
Synonyms   Articles   Notes   Search   Top
Articles:
US Patents: 3,941,828 - Process for the preparation of oxophorones
PubMed: Attraction of the orange mint moth and false celery leaftier moth (Lepidoptera: Crambidae) to floral chemical lures.
J-Stage: Old Yellow Enzyme from Candida macedoniensis Catalyzes the Stereospecific Reduction of the C=C Bond of Ketoisophorone
US Patents: 3,981,311 - Aromatic compositions
PubMed: Recombinant S. cerevisiae expressing Old Yellow Enzymes from non-conventional yeasts: an easy system for selective reduction of activated alkenes.
US Patents: 3,989,857 - Flavoring phenol or phenol derivative containing food or feed with cycloaliphatic derivatives
PubMed: An ene reductase from Clavispora lusitaniae for asymmetric reduction of activated alkenes.
US Patents: 4,014,350 - Aromatic compositions
PubMed: Improved biocatalysts from a synthetic circular permutation library of the flavin-dependent oxidoreductase old yellow enzyme.
PubMed: Comparative characterization of novel ene-reductases from cyanobacteria.
PubMed: Aerobic oxidation of β-isophorone catalyzed by N-hydroxyphthalimide: the key features and mechanism elucidated.
PubMed: Enoate reductases from non conventional yeasts: bioconversion, cloning, and functional expression in Saccharomyces cerevisiae.
PubMed: Bioreduction of α,β-unsaturated ketones and aldehydes by non-conventional yeast (NCY) whole-cells.
PubMed: Composition of sulla (Hedysarum coronarium L.) honey solvent extractives determined by GC/MS: norisoprenoids and other volatile organic compounds.
PubMed: Volatile composition screening of Salix spp. nectar honey: benzenecarboxylic acids, norisoprenoids, terpenes, and others.
PubMed: Rapid method for screening enoate reductase activity in yeasts.
PubMed: Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans.
PubMed: Continuous two-phase flow miniaturised bioreactor for monitoring anaerobic biocatalysis by pentaerythritol tetranitrate reductase.
PubMed: Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation.
PubMed: Metabolite and target transcript analyses during Crocus sativus stigma development.
PubMed: Emission of volatile chemicals from flowering dogwood (cornus Florida L.) flowers.
PubMed: Ketoisophorone transformation by Marchantia polymorpha and Nicotiana tabacum cultured cells.
PubMed: Quality and functionality of saffron: quality control, species assortment and affinity of extract and isolated saffron compounds to NMDA and sigma1 (sigma-1) receptors.
PubMed: A variety of volatile compounds as markers in unifloral honey from dalmatian sage (Salvia officinalis L.).
PubMed: In situ product recovery (ISPR) by crystallization: basic principles, design, and potential applications in whole-cell biocatalysis.
PubMed: Floral odor variation in two heterostylous species of Primula.
PubMed: Cloning and overexpression of the old yellow enzyme gene of Candida macedoniensis, and its application to the production of a chiral compound.
PubMed: Anthropogenic organic contaminants in sediments of the Lippe river, Germany.
PubMed: In situ product removal using a crystallization loop in asymmetric reduction of 4-oxoisophorone by Saccharomyces cerevisiae.
PubMed: Molecular markers of anthropogenic activity in sediments of the Havel and Spree Rivers (Germany).
PubMed: Old Yellow Enzyme from Candida macedoniensis catalyzes the stereospecific reduction of the C=C bond of ketoisophorone.
US Patents: Process for the preparation of a diketone derivative
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