Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | pale yellow to orange clear liquid (est) |
Assay: | 98.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.17000 to 1.18000 @ 25.00 °C.
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Pounds per Gallon - (est).: | 9.736 to 9.819
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Refractive Index: | 1.48000 to 1.49000 @ 20.00 °C.
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Boiling Point: | 181.00 to 182.00 °C. @ 760.00 mm Hg
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Boiling Point: | 81.00 to 82.00 °C. @ 20.00 mm Hg
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Vapor Pressure: | 0.858000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 3.7 ( Air = 1 ) |
Flash Point: | 164.00 °F. TCC ( 73.33 °C. )
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logP (o/w): | 1.000 |
Soluble in: |
| alcohol | | water, 1.332e+004 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Similar Items: note |
allyl 2-furoate |
butyl 2-furoate |
ethyl 2-furoate |
hexyl 2-furoate |
octyl 2-furoate |
propyl 2-furoate |
phenethyl 2-furoate |
Organoleptic Properties:
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Odor Type: fungal |
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Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
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Substantivity: | 64 hour(s) at 100.00 % |
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| fruity mushroom fungal tobacco sweet |
Odor Description: at 10.00 % in dipropylene glycol. | fruity mushroom fungus tobacco sweet Luebke, William tgsc, (1994) |
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Flavor Type: caramellic |
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| sweet caramellic sugar brown sugar musty |
Taste Description:
| sweet caramel brown sugar musty Luebke, William tgsc, (1994) |
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Odor and/or flavor descriptions from others (if found). |
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Bedoukian Research |
METHYL 2-FUROATE ≥99.0%, Kosher |
Odor Description: | A nutty, peppermint, tobacco odor with mushroom undertones For an earthy, tobacco, minty note in specialty fragrances. |
Taste Description: | Sweet, caramel, brown sugar, slightly musty Can be used to add brown sugar/caramel notes to a variety of flavors, especially rum, nut, and coffee. Useful to impart musty notes of mushroom. |
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Nagar Haveli Perfumes & Aromatics |
Methyl 2-Furoate |
Odor Description: | Fruity mushroom fungus tobacco sweet |
Taste Description: | sweet caramel brown sugar musty |
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Cosmetic Information:
Suppliers:
Advanced Biotech |
METHYL FUROATE NATURAL
Odor: Fruity, Sharp |
Apple Flavor & Fragrance |
Methyl 2-furoate
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Bedoukian Research |
METHYL 2-FUROATE
≥99.0%, Kosher Odor: A nutty, peppermint, tobacco odor with mushroom undertones Use: For an earthy, tobacco, minty note in specialty fragrances. Flavor: Sweet, caramel, brown sugar, slightly musty Can be used to add brown sugar/caramel notes to a variety of flavors, especially rum, nut, and coffee. Useful to impart musty notes of mushroom. |
Beijing Lys Chemicals |
Methyl furoate
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BOC Sciences |
For experimental / research use only. |
METHYL 2-FUROATE 99.0%
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Charkit Chemical |
METHYL FUROATE M1360 FEMA 2703
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DeLong Chemicals America |
Methyl 2-furoate, Kosher
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FCI SAS |
METHYL 2 FUROATE
Odor: nutty, tobacco |
Inoue Perfumery |
METHYL 2-FUROATE
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Lluch Essence |
METHYL 2-FUROATE
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M&U International |
METHYL 2-FUROATE, Kosher
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Nagar Haveli Perfumes & Aromatics |
Methyl 2-furoate
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Nagar Haveli Perfumes & Aromatics |
Methyl 2-Furoate
Odor: Fruity mushroom fungus tobacco sweet |
Penta International |
METHYL 2-FUROATE
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Penta International |
METHYL-2-FUROATE NATURAL
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Reincke & Fichtner |
Methyl 2-furoate
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Santa Cruz Biotechnology |
For experimental / research use only. |
Methyl 2-furoate
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Sigma-Aldrich |
Methyl 2-furoate, ≥98%, FG
Odor: berry |
Certified Food Grade Products |
Sigma-Aldrich |
Methyl 2-furoate, natural, 99%, FG
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Synerzine |
Methyl 2-furoate
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Taytonn ASCC |
Methyl 2-furoate
Odor: Green, Marzipan |
TCI AMERICA |
For experimental / research use only. |
Methyl 2-Furancarboxylate >99.0%(GC)
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Tengzhou Jitian Aroma Chemiclal |
Methyl 2-furoate
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Tianjin Danjun International |
Methyl furoate
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United International |
Methyl Furoate
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WholeChem |
Methyl furoate
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 21/22 - Harmful in contact with skin and if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
10 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
gavage-rat LD50 [sex: M,F] 300 mg/kg (Great Lakes Chem. Corp,1998)
oral-rat LD50 300 mg/kg BEHAVIORAL: ATAXIA
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: DYSPNEA National Technical Information Service. Vol. OTS0559247
intraperitoneal-rat LDLo 75 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 174, 1936.
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Dermal Toxicity: |
skin-rabbit LD50 > 1250 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 869, 1979.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for methyl 2-furoate usage levels up to: | | 2.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 30.00 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 37.00 (μg/capita/day) |
Threshold of Concern: | 540 (μg/person/day) |
Structure Class: | II |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | 1.00000 | 1.30000 |
beverages(nonalcoholic): | - | 0.61000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | 0.02000 |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 0.06000 | 1.30000 |
fruit ices: | 0.06000 | 1.30000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 0.66000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18 View page or View pdf |
Flavouring Group Evaluation 66 (FGE.66)[1]:Consideration of furfuryl alcohol and related flavouring substances evaluated by JECFA (55th meeting) structurally related to Furfuryl and furan derivatives with and without additional side chain substituents and heteroatoms evaluated by EFSA in FGE.13 (2005) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009) View page or View pdf |
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 66, Revision 1 (FGE.66Rev1): Consideration of Furfuryl Alcohol and Related Flavouring Substances Evaluated by JECFA (55th meeting) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Safety and efficacy of furfuryl and furan derivatives belonging to chemical group 14 when used as flavourings for all animal species and categories View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
EPI System: | View |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 611-13-2 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 11902 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 2810 |
WGK Germany: | 3 |
| methyl furan-2-carboxylate |
Chemidplus: | 0000611132 |
RTECS: | LV1950000 for cas# 611-13-2 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | furan carboxylic acid methyl ester | | furan-2-carboxylic acid methyl ester | 2- | furancarboxylic acid methyl ester | 2- | furancarboxylic acid, methyl ester | | furoic acid methyl ester | 2- | furoic acid methyl ester | | furoic acid, methyl ester | 2- | furoic acid, methyl ester | 2-( | methoxycarbonyl) furan | 2-( | methoxycarbonyl)furan | | methyl 2-furan carboxylate | | methyl 2-furancarboxylate | | methyl 2-furyl carboxylate | | methyl 2-furylcarboxylate | | methyl furan-2-carboxylate | | methyl pyromucate | | methyl-2-furoate | | pyromucic acid methyl ester |
Articles:
PubMed: | A tunable process: catalytic transformation of renewable furfural with aliphatic alcohols in the presence of molecular oxygen. |
PubMed: | Aerobic oxidation of hydroxymethylfurfural and furfural by using heterogeneous Cox Oy -N@C catalysts. |
PubMed: | Synthesis of terephthalic acid via Diels-Alder reactions with ethylene and oxidized variants of 5-hydroxymethylfurfural. |
PubMed: | Enantioselective synthesis of xanthatin. |
PubMed: | Cobalt-catalyzed C-H borylation. |
PubMed: | Insertional mutagenesis and cloning of the gene required for the biosynthesis of the non-host-specific toxin in Cochliobolus lunatus that causes maize leaf spot. |
PubMed: | Asymmetric synthesis of both enantiomers of arteludovicinolide A. |
PubMed: | An efficient method for the determination of furan derivatives in apple cider and wine by solid phase extraction and high performance liquid chromatography--diode array detector. |
PubMed: | Anti-fish nodaviral activity of furan-2-yl acetate extracted from marine Streptomyces spp. |
PubMed: | [Secondary metabolites of a marine actinomycete Streptomyces sp. (No. 195-02) from South China Sea]. |
PubMed: | Suppression of blood lipid concentrations by volatile Maillard reaction products. |
PubMed: | 5-Furan-2yl[1,3,4]oxadiazole-2-thiol, 5-furan-2yl-4H [1,2,4] triazole-3-thiol and their thiol-thione tautomerism. |
PubMed: | Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure. |
PubMed: | [Bisbenzofuro[3,2-b: 2',3'-e]pyridines]. |
PubMed: | A ceramic electrochemical microreactor for the methoxylation of methyl-2-furoate with direct mass spectrometry coupling. |
PubMed: | Gas chromatography/mass spectrometric characterisation of pyrolysis/silylation products of glucose and cellulose. |
PubMed: | Synthesis of enantiopure dihydropyranones: aldol-based ring expansion of dihydrofurans. |
PubMed: | Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide. |
PubMed: | Generation of Maillard compounds from inulin during the thermal processing of Agave tequilana Weber Var. azul. |
PubMed: | Poikilothermia induced by a 2-furancarboxylic acid derivative. |
PubMed: | High-performance liquid chromatographic determination of methyl anthranilate, hydroxymethylfurfural and related compounds in honey. |
PubMed: | Analysis of the transformation products of dehydro-L-ascorbic acid by ion-pairing high-performance liquid chromatography. |
PubMed: | Characterization of the interaction between human alpha-thrombin and methyl 3-(2-methyl-1-oxopropoxy)[1]benzothieno[3,2-b]furan-2-carboxylate (LY806303) using electrospray mass spectrometry and tandem mass spectrometry. |
PubMed: | Mutagenicity of 3,4-diphenyl-5-nitrofuran analogs in Salmonella typhimurium. |
PubMed: | Synthesis and evaluation of the antitumor properties of esters of 2-furoic acid and 2-furylacrylic acid. |
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