agarospirol
hinesol
 
Notes:
from atractylodes lance rhizome.
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      Product(s):
      23811-08-7 Hinesol >98%
      Source from Rhizomes of Atractylodes lancea DC. Protect liver, antioxidant, antibacterial, antiviral, anti oxygen
       
       
Synonyms   Articles   Notes   Search
CAS Number: 23811-08-7Picture of molecule3D/inchi
Other(deleted CASRN): 26934-83-8
XlogP3-AA: 3.70 (est)
Molecular Weight: 222.37142000
Formula: C15 H26 O
NMR Predictor: Predict (works with chrome or firefox)
Category: fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 90.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 56.00 to  58.00 °C. @ 760.00 mm Hg
Boiling Point: 311.00 to  312.00 °C. @ 760.00 mm Hg (est)
Flash Point: 238.00 °F. TCC ( 114.60 °C. ) (est)
logP (o/w): 4.703 (est)
Soluble in:
 alcohol
 water, 2.216 mg/L @ 25 °C (est)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: spicy
 
 spicy  peppery  woody  
Odor Description:
at 100.00 %. 
spicy peppery woody
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Hinesol 98%
BOC Sciences
For experimental / research use only.
Hinesol >98%
Odor: characteristic
Use: Source from Rhizomes of Atractylodes lancea DC. Protect liver, antioxidant, antibacterial, antiviral, anti oxygen
Santa Cruz Biotechnology
For experimental / research use only.
Hinesol
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for agarospirol usage levels up to:
  1.0000 % in the fragrance concentrate.
 
Recommendation for agarospirol flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 161437
National Institute of Allergy and Infectious Diseases: Data
 2-[(2R,6S)-6,10-dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol
Chemidplus: 0023811087
Synonyms   Articles   Notes   Search   Top
References:
 2-[(2R,6S)-6,10-dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 161437
Pubchem (sid): 135144562
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
HMDB (The Human Metabolome Database): Search
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
 salvia atropatana bunge oil iran 
amber
 amber caraneFR
 angelica seed oil CO2 extractFL/FR
 sarcocaulon mossamedense wood resinoidFR
anisic
bitter fennel seed oil spainFR
balsamic
 amyris wood oilFL/FR
 copaiba balsam oilFL/FR
 copaiba balsam oil replacerFR
 frankincense absoluteFL/FR
 guaiyl acetateFL/FR
 hemlock western oil (tsuga heterophylla) canadaFR
 opoponax absolute (balsamodendron kafal)FL/FR
 tolu balsam oilFL/FR
earthy
 cabralea cangerana root bark oilFR
3-octanolFL/FR
floral
alpha-bisabololFL/FR
 dihydrojasmoneFL/FR
 mimosa absolute franceFL/FR
green
2,5-dimethyl bicyclo(3.2.1)oct-2-eneFR
 octanal diethyl acetalFL/FR
herbal
 anthemis nobilis flower oil romanFL/FR
 canarium luzonicum oilFL/FR
curled parsley seed oilFL/FR
common tansy flower oilFR
common tansy flower oil dutchFR
 theaspiraneFL/FR
peppery
 asarum europaeum oilFR
phenolic
4-methyl-2,6-dimethoxyphenolFL/FR
spicy
 allspice berry absoluteFL/FR
 atractylis root oilFR
 carvacrolFL/FR
4-carvomenthenolFL/FR
 caryophylleneFL/FR
beta-caryophylleneFL/FR
alpha-caryophyllene alcoholFL/FR
 cascarilla oil replacerFL/FR
 cinnamon bark oil ceylonFL/FR
 cinnamon leaf oil ceylonFL/FR
 cinnamon oleoresin ceylonFL/FR
 clove bud absoluteFL/FR
 croton eluteria bark oilFL/FR
 ethyl vinyl ketoneFL/FR
 galangal root oilFL/FR
 ginger oleoresin africaFL/FR
 ginger root oil brazilFL/FR
 ginger root oil chinaFL/FR
 grains of paradise oilFL/FR
 mace absoluteFL/FR
 mace fragranceFR
 mace oilFL/FR
 methyl heptadienoneFL/FR
 myrceneFR
 orthodon dianthera maxim. oil vietnam 
black pepper absoluteFL/FR
 pepper hexanoneFR
black pepper oilFL/FR
black pepper oil replacerFR
black pepper oleoresinFL/FR
 pepper tree berry oilFL/FR
(E,E)-piperineFL/FR
 spicy carbonateFR
(E)-tiglic acidFL/FR
 turmeric root absoluteFL/FR
 zvoulimba leaf oilFR
terpenic
 angelica seed oilFL/FR
para-cymeneFL/FR
 elemi resinoidFL/FR
 frankincense oilFL/FR
 juniperus communis fruit oilFL/FR
laevo-limoneneFL/FR
 pine needle oil dwarfFL/FR
thujonic
common tansy leaf oil dutchFR
common tansy oil canadaFR
vanilla
 vanillin propylene glycol acetalFL/FR
woody
isocaryophylleneCS
 caryophyllene alcohol acetateFR
 caryophyllene formateFL/FR
beta-caryophyllene oxideFL/FR
atlas cedarwood oilFR
alpha-copaene 
 dacrydium franklinii wood oilFR
(3S,5R,8S)-3,8-dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-azulen-1-oneFL/FR
 frankincense fragranceFR
 frankincense oil replacerFR
 frankincense resinoidFL/FR
(E)-germacrene DFL/FR
 guaiacwood oilFL/FR
alpha-guaieneFL/FR
 juniper berry oleoresinFL/FR
 methyl vetivateFR
gamma-muurolene 
 olibanum specialtyFR
 patchouli absoluteFR
 rhubarb oxiraneFR
 spicy pentanoneFL/FR
 spikenard oilFL/FR
 sugi wood oilFR
 xanthoxylum alatum roxb. oilFR
 zedoary bark oilFL/FR
 
For Flavor
 
No flavor group found for these
alpha-bisabololFL/FR
alpha-caryophyllene alcoholFL/FR
 caryophyllene formateFL/FR
alpha-copaene 
(3S,5R,8S)-3,8-dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-azulen-1-oneFL/FR
(E)-germacrene DFL/FR
 grains of paradise oilFL/FR
alpha-guaieneFL/FR
 guaiyl acetateFL/FR
gamma-muurolene 
 orthodon dianthera maxim. oil vietnam 
 salvia atropatana bunge oil iran 
 spikenard oilFL/FR
amber
 angelica seed oilFL/FR
balsamic
 copaiba balsam oilFL/FR
 opoponax absolute (balsamodendron kafal)FL/FR
 tolu balsam oilFL/FR
brown
(E)-tiglic acidFL/FR
cooling
4-carvomenthenolFL/FR
 theaspiraneFL/FR
floral
 dihydrojasmoneFL/FR
fruity
 spicy pentanoneFL/FR
green
 canarium luzonicum oilFL/FR
 elemi resinoidFL/FR
 methyl heptadienoneFL/FR
 octanal diethyl acetalFL/FR
herbal
 angelica seed oil CO2 extractFL/FR
 anthemis nobilis flower oil romanFL/FR
curled parsley seed oilFL/FR
medicinal
 frankincense absoluteFL/FR
musty
3-octanolFL/FR
phenolic
4-methyl-2,6-dimethoxyphenolFL/FR
pine
 pine needle oil dwarfFL/FR
solvent
 methyl phenyl sulfideFL
spicy
 allspice berry absoluteFL/FR
 carvacrolFL/FR
beta-caryophylleneFL/FR
 caryophylleneFL/FR
 cascarilla oil replacerFL/FR
 cinnamon bark oil ceylonFL/FR
 cinnamon leaf oil ceylonFL/FR
 cinnamon oleoresin ceylonFL/FR
 clove bud absoluteFL/FR
 croton eluteria bark oilFL/FR
 ethyl vinyl ketoneFL/FR
 galangal root oilFL/FR
 ginger oleoresin africaFL/FR
 ginger root oil brazilFL/FR
 ginger root oil chinaFL/FR
 mace absoluteFL/FR
 mace oilFL/FR
black pepper absoluteFL/FR
black pepper oilFL/FR
black pepper oleoresinFL/FR
 pepper tree berry oilFL/FR
(E,E)-piperineFL/FR
 turmeric root absoluteFL/FR
terpenic
para-cymeneFL/FR
 juniperus communis fruit oilFL/FR
laevo-limoneneFL/FR
vanilla
 vanillin propylene glycol acetalFL/FR
waxy
 mimosa absolute franceFL/FR
woody
 amyris wood oilFL/FR
beta-caryophyllene oxideFL/FR
 frankincense oilFL/FR
 frankincense resinoidFL/FR
 guaiacwood oilFL/FR
 juniper berry oleoresinFL/FR
 zedoary bark oilFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 fixer 
 spiceFR
 woodyFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 agarwood oil @ 0.03%
Data  GC  Search  PMC Picture
 agarwood oil @ 4.80%
Data  GC  Search  PMC Picture
 atractylis oil
Search Trop  Picture
 atractylodes lancea
Search Trop  Picture
 fungus infected agarwood aquillaria agalocha
Search  PMC Picture
 phoebe oil brazil @ 3.25%
Data  GC  Search Trop  Picture
 tansy oil (tanacetum annum l.) marocco @ 0.70%
Data  GC  Search Trop  Picture
 zingiber officinale root oil china @ 3.00%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
2-[(2R,10S)-6,10-dimethyl spiro[4.5]dec-6-en-2-yl]-2-propanol
2-[(2R,10S)-6,10-dimethylspiro[4.5]dec-6-en-2-yl]-2-propanol
2-[(2R,6S)-6,10-dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol
 hinesol
epi-hinesol
 spiro(4.5)dec-6-ene-2-methanol, a,a,6,10-tetramethyl-, (2R-(2a,5a(S*)))-
(2R-(2alpha,5alpha(S*)))- alpha,alpha,6,10-tetramethyl spiro(4.5)dec-6-ene-2-methanol
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: [Studies on terpenoids from Zygophyllum fabago].
PubMed: Sulphur-containing compounds in the essential oil of Ferula alliacea roots and their mass spectral fragmentation patterns.
PubMed: [Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea].
PubMed: Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells.
PubMed: Traditional herbal medicine for the control of tropical diseases.
PubMed: [Study on the chemical components of volatile oil from Euphorbia pekinensis radix].
PubMed: Molecular docking and ADME studies of natural compounds of Agarwood oil for topical anti-inflammatory activity.
PubMed: Composition and evaluation of the anti-inflammatory and anticancer activities of the essential oil from Annona sylvatica A. St.-Hil.
PubMed: Chemical composition and in vitro antimicrobial activity of the essential oil of Cyclotrichium leucotrichum from Iran.
PubMed: In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei.
PubMed: Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis.
PubMed: Chemical composition of volatile oils of Aquilaria malaccensis (Thymelaeaceae) from Malaysia.
PubMed: [Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis].
PubMed: [Advances in chemistry, molecular biology and pharmacological of Cangzhu].
PubMed: Identification of volatile compounds of Atractylode lancea rhizoma using supercritical fluid extraction and GC-MS.
PubMed: [Fingerprint of volatile oil of Atractylodes lancea by GC-MS].
PubMed: [GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood].
PubMed: [Studies on chemical constituents in essential oil from wild Atractylodes lancea in dabie mountains].
PubMed: A phosphine-catalyzed [3+2] cycloaddition strategy leading to the first total synthesis of (-)-hinesol.
PubMed: [The naphtha composing characteristics of geoherbs of Atractylodes lancea].
PubMed: [GC-MS analysis of essential oils from rhizomes of Atractylodes lancea (Thunb.) DC. and A. chinensis (DC.) Koidz].
PubMed: Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying.
PubMed: Effects of sesquiterpenoids from "Oriental incenses" on acetic acid-induced writhing and D2 and 5-HT2A receptors in rat brain.
PubMed: Inhibition of H+,K+ -ATPase by hinesol, a major component of So-jutsu, by interaction with enzyme in the E1 state.
PubMed: Biotransformation of hinesol isolated from the crude drug Atractylodes lancea by Aspergillus niger and Aspergillus cellulosae.
PubMed: Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures.
PubMed: Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants.
PubMed: A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.
PubMed: [Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes].
PubMed: Effect of jinkoh-eremol and agarospirol from agarwood on the central nervous system in mice.
PubMed: Botanical and chemical evaluation of Atractylodes lancea plants propagated in vitro and by division of the rhizome.
PubMed: Intestinal motility enhancing effect of Atractylodes lancea rhizome.
PubMed: Antihepatotoxic principles of Atractylodes rhizomes.
PubMed: Stereochemical relationships in spirovetivane sesquiterpenes: the total synthesis of hinesol.
PubMed: Studies on the constituents of atractylodes. X. Correlation of hinesol and beta-vetivone.
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