Category: flavoring agents and adjuvants, formulation aids, humectants, solvents and vehicles
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear oily liquid (est) |
Assay: | 99.00 to 100.00 %
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Food Chemicals Codex Listed: | Yes |
Specific Gravity: | 1.15900 to 1.16400 @ 25.00 °C.
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Pounds per Gallon - (est).: | 9.644 to 9.686
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Refractive Index: | 1.42900 to 1.43200 @ 20.00 °C.
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Melting Point: | 3.00 to 4.00 °C. @ 760.00 mm Hg
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Boiling Point: | 258.00 to 260.00 °C. @ 760.00 mm Hg
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Boiling Point: | 130.00 to 131.00 °C. @ 7.00 mm Hg
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Acid Value: | 1.00 max. KOH/g
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PH Number: | 7.00
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Vapor Pressure: | 0.014000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 7.52 ( Air = 1 ) |
Flash Point: | 280.00 °F. TCC ( 137.78 °C. )
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logP (o/w): | 0.250 |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | water, 2.152e+004 mg/L @ 25 °C (est) | | water, 5.80E+04 mg/L @ 25 °C (exp) |
Organoleptic Properties:
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Odor Type: fruity |
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Odor Strength: | low |
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Substantivity: | 204 hour(s) at 100.00 % |
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| clean tropical fruity |
Odor Description: at 100.00 %. | mild clean tropical fruity Luebke, William tgsc, (1987) |
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| clean creamy acidic |
Odor Description:
| Clean, creamy and slightly acidic Mosciano, Gerard P&F 20, No. 1, 31, (1995) |
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Flavor Type: creamy |
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| creamy oily |
Taste Description:
| creamy with an oily mouthfeel Mosciano, Gerard P&F 20, No. 1, 31, (1995) |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
ABITEC |
Captex 500
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Advanced Biotech |
TRIACETIN NATURAL
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Advanced Biotech |
TRIACETIN SYNTHETIC
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Allan Chemical |
Glycerol Triacetate
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Anhui Haibei |
Triacetin
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Apple Flavor & Fragrance |
Glyceryl Triacetate
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Aromiens International |
Triacetin Natural
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Augustus Oils |
Triacetin
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Services |
Berjé |
Triacetin FCC
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Media |
BOC Sciences |
For experimental / research use only. |
Triacetin 98%
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Charkit Chemical |
TRIACETIN A, 90002
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Charkit Chemical |
TRIACETIN F, 90020
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Charkit Chemical |
TRIACETIN F
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Charkit Chemical |
TRIACETIN FCC FOOD GRADE
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Charkit Chemical |
TRIACETIN FCC/USP KOSHER
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Charkit Chemical |
TRIACETIN NATURAL FEMA 2007
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Eastman Chemical |
Eastman™ Triacetin, Kosher, Food Grade
Odor: characteristic Use: Eastman™ Triacetin (glyceryl triacetate) is used as an ingredient in many food and cosmetic products. Its high solvency power and low volatility make triacetin a good solvent and fixative for many flavors and fragrances. One of its main uses is as a plasticizer in chewing gum. The United States Food and Drug Administration affirmed triacetin as generally recognized as safe (GRAS) for use in human food. It is also generally recognized as safe in animal feeds, as a pesticide adjuvant, and in food packaging. Eastman™ Triacetin, Kosher, Food Grade, meets all Food Chemicals Codex (FCC) specifications and is manufactured under good manufacturing practices (GMP). All kosher products produced by Eastman are manufactured under rabbinical supervision in full accordance with Jewish dietary law. |
ECSA Chemicals |
TRIACETIN KOSHER - PALM FREE
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ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
ECSA Chemicals |
TRIACETIN KOSHER
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ECSA Chemicals |
TRIACETIN RSPO
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EMD Millipore |
For experimental / research use only. |
Triacetin
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Ernesto Ventós |
TRIACETIN
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Foodchem International |
Glycerol Triacetate
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Fuzhou Farwell |
Triacetin 99.5%min
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Glentham Life Sciences |
Triacetin
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Graham Chemical |
Triacetin
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Indukern F&F |
TRIACETINE
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Jiangyin Healthway |
Triacetin
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New functional food ingredients |
Lluch Essence |
TRIACETIN
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M&U International |
Triacetin
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Natural Advantage |
Triacetin Nat USOC
Flavor: creamy, oily, sweet |
Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries |
Oleo Solutions |
Edenor GTA
Odor: characteristic Use: Flavours and Fragrances, Adhesives and Lubricants, Industrial, Inks and Coatings, Pharmaceutical and Veterinary |
OQEMA |
Triacetin
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OQEMA |
Triacetin
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Penta International |
TRIACETIN EP GRADE
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Penta International |
TRIACETIN FCC
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Penta International |
TRIACETIN NATURAL
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Penta International |
TRIACETIN REGULAR GRADE
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Penta International |
TRIACETIN USP
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Prinova |
Triacetin
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R C Treatt & Co Ltd |
Triacetin
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Reincke & Fichtner |
Triacetin
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Santa Cruz Biotechnology |
For experimental / research use only. |
Glyceryl triacetate
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Sigma-Aldrich |
Triacetin, 99%, FCC, FG
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Certified Food Grade Products |
Silver Fern Chemical |
Triacetin
Odor: characteristic Use: Triacetin is used as a plasticizer, fixative in perfumery and cosmetics, specialty solvent, a carbon dioxide removal agent, in medicines for its antifungal properties, a fuel additive, and in cigarettes. |
Synerzine |
TRIACETIN, NATURAL
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Synerzine |
Triacetin
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SysKem Chemie |
Triacetin
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TCI AMERICA |
For experimental / research use only. |
Triacetin >99.0%(GC)
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Tengzhou Xiang Yuan Aroma Chemicals |
Triacetin
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The Lermond Company |
TRIACETIN
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Vigon International |
TRIACETIN NATURAL
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Vigon International |
Triacetin
Odor: FATTY |
WholeChem |
Triacetin, 99%+, FCC, FG
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WholeChem |
Triacetin, Natural
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Acute toxicity, Oral (Category 4), H302
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GHS Label elements, including precautionary statements |
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Pictogram | |
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Signal word | Warning |
Hazard statement(s) |
H302 - Harmful if swallowed
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Precautionary statement(s) |
P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P330 - Rinse mouth. P501 - Dispose of contents/ container to an approved waste disposal plant.
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Human Experience: |
100 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
intravenous-rabbit LD50 750 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
oral-mouse LD50 1100 mg/kg PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: STIFFNESS Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 22, Pg. 368, 1963.
intravenous-mouse LD50 1600 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Acta Physiologica Scandinavica. Vol. 40, Pg. 338, 1957.
intraperitoneal-mouse LD50 1400 mg/kg BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: STIFFNESS
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 22, Pg. 368, 1963.
intravenous-dog LD50 1500 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
oral-frog LDLo 150 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
intramuscular-guinea pig LDLo 1740 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA Journal of Pharmacology and Experimental Therapeutics. Vol. 76, Pg. 189, 1942.
intraperitoneal-rat LD50 2100 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
oral-rat LD50 3000 mg/kg AMA Archives of Industrial Health. Vol. 21, Pg. 28, 1960.
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Dermal Toxicity: |
subcutaneous-mouse LD50 2300 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 26, 1941.
subcutaneous-rat LD50 2800 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 26, 1941.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents and adjuvants, formulation aids, humectants, solvents and vehicles |
Recommendation for triacetin usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 1000.00000 |
beverages(nonalcoholic): | - | 190.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | 4100.00000 |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 60.00000 | 2000.00000 |
fruit ices: | 60.00000 | 2000.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 560.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
References:
Other Information:
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
FDA Substances Added to Food (formerly EAFUS): | View |
CHEBI: | View |
CHEMBL: | View |
KEGG (GenomeNet): | D00384 |
HMDB (The Human Metabolome Database): | HMDB29592 |
FooDB: | FDB000751 |
Export Tariff Code: | 2915.39.9000 |
FDA Listing of Food Additive Status: | View |
VCF-Online: | VCF Volatile Compounds in Food |
ChemSpider: | View |
Wikipedia: | View |
Formulations/Preparations: •grades: technical; cp; nd; fcc
•food-grade triacetin must be at least 98.5% c9h14o6, and it must not contain >5 mgkg heavy metals (as pb) or>0.2% water.
•usp-grade triacetin must contain not less than 97.0% and not greater than 100.5% c9h14o6, calculated on the anhydrous basis
•trade names: enzaactin; estoll 1581; fungacetin; glyped; kessocoflex tra; kadoflex triacetin; only-clear nail; priacetin 1581; ujostabil; and vanay.
•enzactin (ayerst). topical: aerosol 15% in 3 oz containers; cream 250 mgg in 1 oz containers; powder 33.3% in 1 12 oz containers.
•fungoid tincture (pedinol): solution: triacetin, cetylpyridinium chloride, chloroxylenol, benzyl alcohol, acetone, benzalkonium chloride (in 30 ml and pint). fungoid (pedinol) solution: triacetin, peg-8, cetylpyridinium chloride, chloroxylenol and benzalkonium chloride (in 15 ml). fungoid cream (pedinol) cream: triacetin, cetylpyridinium chloride, chloroxylenol, mineral oil, lanolin, propylene glycol, parabens in a vanishing cream base (in 30 g).
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Potential Blenders and core components note
Potential Uses:
| coupler for oil and water emulsions | |
| film formers | |
| solvents | |
Occurrence (nature, food, other): note
Synonyms:
| acetic acid 1,2,3-propane triyl ester | 2- | acetyloxy-1-(acetyloxymethyl)ethyl acetate | 2-( | acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate | | captex 500 | 1,3- | diacetyloxypropan-2-yl acetate | | enzactin | | fungacetin | | glycerin triacetate | | glycerol triacetate | | glyceryl triacetate | 1,2,3- | propane triol triacetate | 1,2,3- | propane triyl triacetate | | propane-1,2,3-triyl triacetate | 1,2,3- | propanetriol triacetate | 1,2,3- | propanetriol, triacetate | 1,2,3- | propanetriyl triacetate | ( | tri-)acetin | | triacetin EP grade | | triacetin FCC | | triacetin food grade | | triacetin regular grade | | triacetin synthetic | | triacetin USP | | triacetine | 1,2,3- | triacetoxypropane | | triacetyl glycerine | | triacetyl glycerol | | triacetylglycerol | | vanay |
Articles:
PubMed: | Stability of citral in oil-in-water emulsions prepared with medium-chain triacylglycerols and triacetin. |
PubMed: | Influence of flavor solvent on flavor release and perception in sugar-free chewing gum. |
PubMed: | The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes. |
PubMed: | Short-chain flavor ester synthesis in organic media by an E. coli whole-cell biocatalyst expressing a newly characterized heterologous lipase. |
PubMed: | The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes. |
PubMed: | Determination of volatile organic compounds (VOCs) from wrapping films and wrapped PDO Italian cheeses by using HS-SPME and GC/MS. |
PubMed: | Structural changes and triacetin migration of starch acetate film contacting with distilled water as food simulant. |
PubMed: | Bacteriophage 933W encodes a functional esterase downstream of the Shiga toxin 2a operon. |
PubMed: | Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. |
PubMed: | Impact of flavour solvent (propylene glycol or triacetin) on vanillin, 5-(hydroxymethyl)furfural, 2,4-decadienal, 2,4-heptadienal, structural parameters and sensory perception of shortcake biscuits over accelerated shelf life testing. |
PubMed: | Plasticization effect of triacetin on structure and properties of starch ester film. |
PubMed: | Rice (Oryza sativa) lipase: molecular cloning, functional expression and substrate specificity. |
PubMed: | Mechanisms of propylene glycol and triacetin pyrolysis. |
PubMed: | An oral colon-targeting controlled release system based on resistant starch acetate: synthetization, characterization, and preparation of film-coating pellets. |
PubMed: | Stability of citral in oil-in-water emulsions prepared with medium-chain triacylglycerols and triacetin. |
PubMed: | Glyceryl triacetate for Canavan disease: a low-dose trial in infants and evaluation of a higher dose for toxicity in the tremor rat model. |
PubMed: | Influence of flavor solvent on flavor release and perception in sugar-free chewing gum. |
PubMed: | Development of a self-emulsifying formulation that reduces the food effect for torcetrapib. |
PubMed: | Emissions from cooking microwave popcorn. |
PubMed: | Effect of salts and plasticizers on stability of shellac film. |
PubMed: | Microemulsions as transdermal drug delivery vehicles. |
PubMed: | Stable bioavailability of cyclosporin A, regardless of food intake, from soft gelatin capsules containing a new self-nanoemulsifying formulation. |
PubMed: | Progress toward acetate supplementation therapy for Canavan disease: glyceryl triacetate administration increases acetate, but not N-acetylaspartate, levels in brain. |
PubMed: | The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes. |
PubMed: | Optimized synthesis of lipase-catalyzed hexyl acetate in n-hexane by response surface methodology. |
PubMed: | Open-label study of the safety and efficacy of Fungoid tincture in patients with distal subungual onychomycosis of the toes. |
PubMed: | Triacetin as food additive in gummy candy and other foodstuffs on the market. |
PubMed: | Cell-bound lipase and esterase of Brevibacterium linens. |
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