Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 97.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.06610 to 1.07000 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.871 to 8.903
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Refractive Index: | 1.52300 to 1.52700 @ 20.00 °C.
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Melting Point: | -55.00 to -52.00 °C. @ 760.00 mm Hg
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Boiling Point: | 85.00 to 87.00 °C. @ 7.00 mm Hg
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Boiling Point: | 215.00 to 217.50 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.528000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 4.7 ( Air = 1 ) |
Flash Point: | 186.00 °F. TCC ( 85.56 °C. )
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logP (o/w): | 2.210 |
Soluble in: |
| alcohol | | water, 1105 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: medicinal |
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Odor Strength: | medium , recommend smelling in a 1.00 % solution or less |
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Substantivity: | 64 hour(s) at 100.00 % |
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| acidic fruity nutmeg neroli |
Odor Description: at 1.00 % in dipropylene glycol. | acid fruity nutmeg neroli Luebke, William tgsc, (1998) |
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| sweet cooling medicinal root beer |
Odor Description:
| Sweet, cooling, medicinal, root beer-like Mosciano, Gerard P&F 17, No. 3, 57, (1992) |
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Flavor Type: chemical |
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| chemical medicinal spicy cooling root beer |
Taste Description:
| Chemical, medicinal, spice, cooling root beer-like Mosciano, Gerard P&F 17, No. 3, 57, (1992) |
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Odor and/or flavor descriptions from others (if found). |
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Sigma-Aldrich |
1,3-Dimethoxybenzene, ≥98%, FG |
Odor Description: | coconut; hazelnut; earthy. |
Taste Description: | chemical medicinal spice cooling root beer |
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Moellhausen |
DIMETHYL RESORCINOL |
Odor Description: | nutty, roasted note, phenolic, stuffy |
Taste Description: | chemical, medicinal, spice, cooling root beer-like |
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Lluch Essence |
DIMETHOXY BENZENE 98% |
Odor Description: | PHENOLIC, RANCID, ROASTED |
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Cosmetic Information:
Suppliers:
Aroma Aromatics & Flavours |
Resorcinol Dimethyl Ether
Flavor: Sweet earthy and intense nut like The either can introduce very pleasant and usual inimitable notes of chypres, Fougeres, clover, Hycinth etc. It is stable in soap. It can also be used as a novel additive to mossbase.
As flavour it is an important part of Hazelnut imitation flavour, coconut, walnut, fruit complexes and in trace amount in vanilla imitation. The normal concentration is about 5 to 10 ppm in finished products. |
Augustus Oils |
1,3 Dimethoxy Benzene
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Services |
Beijing Lys Chemicals |
1,3-Dimethoxy benzene
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Berjé |
Dimethyl Resourcinol
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Media |
BOC Sciences |
For experimental / research use only. |
meta-Dimethyl Hydroquinone 98%
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EMD Millipore |
For experimental / research use only. |
Resorcinol dimethyl ether
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Ernesto Ventós |
1,3-DIMETHOXYBENZENE
Odor: FTUITY REMINISCENT OF NEROLIN |
Lluch Essence |
DIMETHOXY BENZENE 98%
Odor: PHENOLIC, RANCID, ROASTED |
M&U International |
1,3-DIMETHOXY BENZENE
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Moellhausen |
DIMETHYL RESORCINOL
Odor: nutty, roasted note, phenolic, stuffy Flavor: chemical, medicinal, spice, cooling root beer-like |
Penta International |
DIMETHYL RESORCINOL
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Reincke & Fichtner |
m-Dimethoxybenzene
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Santa Cruz Biotechnology |
For experimental / research use only. |
1,3-Dimethoxybenzene ≥98%
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Sigma-Aldrich |
1,3-Dimethoxybenzene, ≥98%, FG
Odor: coconut; hazelnut; earthy. |
Certified Food Grade Products |
Synerzine |
m-Dimethoxybenzene
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Taytonn ASCC |
1,3-Dimethoxybenzene
Odor: Nutmeg, Fruity, Acidic |
TCI AMERICA |
For experimental / research use only. |
1,3-Dimethoxybenzene >99.0%(GC)
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United International |
1,3-Dimethoxy benzene
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WholeChem |
1,3-Dimethoxy benzene
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-rat LD50 2500 mg/kg (Moreno, 1978l)
oral-rat LD50 [sex: M,F] 2560 mg/kg (Bär & Griepentrog, 1967)
intraperitoneal-mouse LD50 900 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
BEHAVIORAL: TREMOR Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 185, 1957.
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for meta-dimethyl hydroquinone usage levels up to: | | 1.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 4.60 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 2.00 (μg/capita/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 8.00000 |
beverages(nonalcoholic): | - | 3.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 5.00000 |
fruit ices: | - | 5.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 5.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 23 (FGE.23): Aliphatic, alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16 and 26 (Commission Regulation (EC) No 1565/2000 of 18 July 2000 View page or View pdf |
Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 23, Revision 1 (FGE.23Rev1): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 26 and 30[1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010) View page or View pdf |
Scientific Opinion on the safety and efficacy of aromatic ethers including anisole derivatives (chemical group 26) when used as feed additives for all animal species View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 151-10-0 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 9025 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 1,3-dimethoxybenzene |
Chemidplus: | 0000151100 |
RTECS: | CZ6474000 for cas# 151-10-0 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzene, 1,3-dimethoxy- | | benzene, m-dimethoxy- | | benzene,3-dimethoxy- | 1,3- | dimethoxy benzene | 1,3- | dimethoxy-benzene | 1,3- | dimethoxybenzene | m- | dimethoxybenzene | meta- | dimethoxybenzene | 1,3- | dimethoxybenzol | meta- | dimethyl hydroquinone | | dimethyl resorcinol | | dimethyl resourcinol | m- | dimethylhydroquinone | | dimethylresorcinol | 3- | methoxyanisole | | resorcinol dimethyl ether |
Articles:
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