Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear liquid (est) |
Assay: | 97.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.91800 to 0.92500 @ 25.00 °C.
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Pounds per Gallon - (est).: | 7.639 to 7.697
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Refractive Index: | 1.47700 to 1.48100 @ 20.00 °C.
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Melting Point: | 8.60 °C. @ 760.00 mm Hg
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Boiling Point: | 320.00 to 329.00 °C. @ 760.00 mm Hg
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Boiling Point: | 130.00 °C. @ 0.50 mm Hg
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Acid Value: | 1.00 max. KOH/g
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Vapor Pressure: | 0.000176 mmHg @ 25.00 °C. (est) |
Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
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logP (o/w): | 6.100 (est) |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | water, very slightly | | water, 0.2213 mg/L @ 25 °C (est) |
Stability: |
| APC: - | | candle: traces - 0.5% | | detergent: traces - 0.5% | | fine fragrances: 0.1 - 2% | | shampoo: traces - 0.5% | | shower gel: traces - 0.5% | | soap: traces - 0.5% | | softener: traces - 0.5% |
Organoleptic Properties:
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Odor Type: musk |
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Odor Strength: | high , recommend smelling in a 10.00 % solution or less |
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Substantivity: | 400 hour(s) at 100.00 % |
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| sweet musk animal powdery fatty natural |
Odor Description: at 10.00 % in dipropylene glycol. | sweet musk animal powdery fatty natural Luebke, William tgsc, (1986) |
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| sweet floral musk soapy |
Odor Description: at 0.20 %. | sweet fragrant perfume, musky with floral and soapy shaving cream like nuances. Mosciano, Gerard, (2009) |
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Flavor Type: musk |
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| sweet musk floral soapy woody bitter |
Taste Description: at 1.00 ppm. | sweet, musk like, perfume, soapy with woody and bitter nuances Mosciano, Gerard, (2009) |
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Odor and/or flavor descriptions from others (if found). |
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Firmenich |
MUSCONE for fragrance |
Odor Description: | A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk It can be used to give elegant and warm animal notes and adds lift and
diffusion to any perfume. Important for the reconstitution of natural musk. |
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Pell Wall Perfumes |
Muscone |
Odor Description: | Musk, powdery, soft, animalic. Exalting. Fixative According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”. |
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IFF |
Muscor |
Odor Description: | Soft, sweet, musky with animalic tonalities |
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Perfumery Laboratory |
MUSCON LAEVO 20% Firmenich (MUSCONE LAEVO 954117 Firmenich) |
Odor Description: | trong aroma of Thonky musk, which has good diffusion |
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Takasago |
l-Muscone |
Odor Description: | musk animal powdery |
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Cosmetic Information:
Suppliers:
ACS International |
Muscone
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Operational Capabilities |
ACS International |
Muscone
Odor: sweet musk floral woody soapy |
Alfa Biotechnology |
For experimental / research use only. |
Muscone 98%
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Augustus Oils |
Muscone
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Services |
Azelis UK |
MUSCONE
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BOC Sciences |
For experimental / research use only. |
Muscone >98%
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Coompo |
For experimental / research use only. |
Muscone from Plants ≥98%
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Ernesto Ventós |
MUSCONE FIRMENICH 962195
Odor: VERY SOFT, SWEET, MUSKY |
Ernesto Ventós |
MUSCOR IFF
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Fine Fragrances Pvt Ltd |
Muscone
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Firmenich |
MUSCONE
for fragrance Odor: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk Use: It can be used to give elegant and warm animal notes and adds lift and
diffusion to any perfume. Important for the reconstitution of natural musk. |
IFF |
Muscor
Odor: Soft, sweet, musky with animalic tonalities |
Indukern F&F |
MUSCONE
Odor: SMOOTH, SWEET, MUSK |
Liaison Carbone |
MUSCONE LAEVO 954117
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Lluch Essence |
MUSCONE
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M&U International |
Muscone
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Moellhausen |
MUSCONE
Odor: musky, slightly fruity, erogenic |
Pell Wall Perfumes |
Muscone
Odor: Musk, powdery, soft, animalic. Exalting. Fixative Use: According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”. |
Penta International |
3-METHYL-1-CYCLOPENTADECANONE
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Perfumer Supply House |
L-Muscone (Takasago) – for a limited time
Odor: The key component of musk, this synthetic version has a sweet, powdery, animalic aroma |
Perfumery Laboratory |
MUSCON LAEVO 20% Firmenich (MUSCONE LAEVO 954117 Firmenich)
Odor: trong aroma of Thonky musk, which has good diffusion |
Prodasynth |
MUSCONE
(> 95%) Odor: SOFT, SWEET, MUSKY |
Santa Cruz Biotechnology |
For experimental / research use only. |
Muscone ≥98%
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Takasago |
l-Muscone
Odor: musk animal powdery |
The Fragrance Museum |
TCI AMERICA |
For experimental / research use only. |
Muscone >97.0%(GC)
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Tianjin Danjun International |
3-Methyl-1-cyclopentadecanone
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Vigon International |
Muscone
Odor: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk |
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
30 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 [sex: M,F] > 5000 mg/kg (Oh et al., 1997)
intravenous-mouse LD50 152 mg/kg Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 12, Pg. 236, 1981.
intraperitoneal-mouse LD50 270 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 12, Pg. 236, 1981.
oral-rat LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 749, 1982.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 749, 1982.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for dextro,laevo-muscone usage levels up to: | | 2.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.37 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.009 (μg/capita/day) |
Structure Class: | II |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 8 |
Click here to view publication 8 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.05000 |
beverages(nonalcoholic): | - | 0.03000 |
beverages(alcoholic): | - | 0.02000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | 0.05000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 0.03000 |
fruit ices: | - | 0.03000 |
gelatins / puddings: | - | 0.02000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of alicyclic substances used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 541-91-3 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 10947 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 3-methylcyclopentadecan-1-one |
Chemidplus: | 0000541913 |
RTECS: | GY0950000 for cas# 541-91-3 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| cyclopentadecanone, 3-methyl- | 3- | methyl cyclopentadecan-1-one | 3- | methyl cyclopentadecanone | | methyl exaltone | 3- | methyl-1-cyclopentadecanone | 3- | methyl-cyclopentadecanone | 3- | methylcyclopentadecan-1-one | 3- | methylcyclopentadecanone | | methylexaltone | | moschus ketone | dextro,laevo- | muscone | DL- | muscone | | muscone (Firmenich) | | muscor (IFF) | | muskone |
Articles:
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