Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to yellow clear oily liquid (est) |
Assay: | 95.00 to 100.00 % sum of isomers
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Equivalence Factor for Assay: | 129.08 |
Food Chemicals Codex Listed: | Yes |
Specific Gravity: | 0.98300 to 0.98900 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.180 to 8.229
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Refractive Index: | 1.51600 to 1.52100 @ 20.00 °C.
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Boiling Point: | 305.00 °C. @ 760.00 mm Hg
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Boiling Point: | 198.00 to 200.00 °C. @ 15.00 mm Hg
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Acid Value: | 1.00 max. KOH/g
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Vapor Pressure: | 0.000017 mmHg @ 25.00 °C. (est) |
Flash Point: | 230.00 °F. TCC ( 110.00 °C. )
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logP (o/w): | 5.705 (est) |
Soluble in: |
| alcohol | | water, 0.1831 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: balsamic |
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Odor Strength: | medium |
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Substantivity: | > 8 hour(s) at 100.00 % |
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| sweet amber ylang rose |
Odor Description: at 100.00 %. | sweet amber ylang rose |
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Odor and/or flavor descriptions from others (if found). |
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Bedoukian Research |
GERANYL BENZOATE ≥97.0%, FCC, Kosher |
Odor Description: | Long-lasting rose, amber Can be used to extend the odor of rose and geranium compositions. |
Taste Description: | amber Used in fruit cocktail, pear, peach, apricot and cherry flavors. |
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Cosmetic Information:
Suppliers:
Safety Information:
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
2 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 887, 1974.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 887, 1974.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
limits in the finished product for - "leave on the skin contact": | | 0.5000 % Recommendation.
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limits in the finished product for - "wash off the skin contact": | | 0.5000 % Recommendation.
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limits in the finished product for - "no skin contact": | | 4.0000 % Recommendation.
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Recommendation for geranyl benzoate usage levels up to: | | 4.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 3.40 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.03 (μg/capita/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.50000 |
beverages(nonalcoholic): | 0.10000 | 0.13000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 0.16000 | 0.25000 |
fruit ices: | 0.16000 | 0.25000 |
gelatins / puddings: | - | 0.50000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 0.50000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of benzyl derivatives used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Flavouring Group Evaluation 202: 3-Alkylated aliphatic acyclic alpha,beta-unsaturated aldehydes and precursors with or without additional double bonds from chemical subgroup 1.1.3 of FGE.19[1] View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 94-48-4 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 60980 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 3,7-dimethylocta-2,6-dienyl benzoate |
Chemidplus: | 0000094484 |
RTECS: | RG5925300 for cas# 94-48-4 |
| [(2E)-3,7-dimethylocta-2,6-dienyl] benzoate |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzoic acid geraniol ester | | benzoic acid geranyl ester | | benzoic acid, geraniol ester | | dimethyl-2,6-octadien-1-yl benzoate | (E)-3,7- | dimethyl-2,6-octadien-1-yl benzoate | trans-3,7- | dimethyl-2,6-octadien-1-yl benzoate | (E)-3,7- | dimethyl-2,6-octadiene-1-yl benzoate | (2E)-3,7- | dimethyl-2,6-octadienyl benzoate | (2E)-3,7- | dimethylocta-2,6-dien-1-yl benzoate | 3,7- | dimethylocta-2,6-dienyl benzoate | [(2E)-3,7- | dimethylocta-2,6-dienyl] benzoate | | geraniol benzoate | (E)- | geranyl benzoate | | geranyl benzoate S | (E)- | neryl benzoate | 2,6- | octadien-1-ol, 3,7-dimethyl-, benzoate, (2E)- | 2,6- | octadien-1-ol, 3,7-dimethyl-, benzoate, (E)- |
Articles:
PubMed: | In vivo anti-inflammatory activity of some naturally occurring O- and N-prenyl secondary metabolites. |
PubMed: | Antiherbivore prenylated benzoic acid derivatives from Piper kelleyi. |
PubMed: | Synthesis of 3-farnesyl salicylic acid, a novel antimicrobial from Piper multiplinervium. |
PubMed: | Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
PubMed: | Cloning and expression analysis of ten genes associated with picrosides biosynthesis in Picrorhiza kurrooa. |
PubMed: | Contact and fumigant toxicity of Pinus densiflora needle hydrodistillate constituents and related compounds and efficacy of spray formulations containing the oil to Dermatophagoides farinae. |
PubMed: | Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. |
PubMed: | Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]. |
PubMed: | Activation of the human transient receptor potential vanilloid subtype 1 by essential oils. |
PubMed: | Geranylation of benzoic acid derivatives by enzymatic extracts from Piper crassinervium (Piperaceae). |
PubMed: | W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and AKT inactivation caused by Ras and Rac. |
PubMed: | Functional characterization of LePGT1, a membrane-bound prenyltransferase involved in the geranylation of p-hydroxybenzoic acid. |
PubMed: | Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). |
PubMed: | Isolation and structural determination of xerophytolic acid A, a 3-geranyl-4-hydroxybenzoate derivative from Xerophyta plicata. |
PubMed: | In-vitro human skin penetration of the fragrance material geranyl nitrile. |
PubMed: | Functional characterization of OsPPT1, which encodes p-hydroxybenzoate polyprenyltransferase involved in ubiquinone biosynthesis in Oryza sativa. |
PubMed: | Geranyl N-dimethylallylanthranilate, a new compound from Esenbeckia yaaxhokob. |
PubMed: | Electroantennographic and behavioral responses of the sphinx moth Manduca sexta to host plant headspace volatiles. |
PubMed: | Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases. |
PubMed: | Chemicals in laboratory room air stimulate olfactory neurons of female Bombyx mori. |
PubMed: | 3-Geranyl-4-hydroxy-5-(3'-methyl-2'-butenyl)benzoic acid as an anti-inflammatory compound from Myrsine seguinii. |
PubMed: | Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer. |
PubMed: | Stringent structural requirements for anti-Ras activity of S-prenyl analogues. |
PubMed: | Isoprenyl phenyl ethers from liverworts of the genus Trichocolea: cytotoxic activity, structural corrections, and synthesis. |
PubMed: | Floral Scent Production in Clarkia (Onagraceae) (I. Localization and Developmental Modulation of Monoterpene Emission and Linalool Synthase Activity). |
PubMed: | Characterization and mechanism of (4S)-limonene synthase, a monoterpene cyclase from the glandular trichomes of peppermint (Mentha x piperita). |
PubMed: | Effects of olfactory stimulation with jasmin and its component chemicals on the duration of pentobarbital-induced sleep in mice. |
PubMed: | Mechanism of the pyrophosphate migration in the enzymatic cyclization of geranyl and linalyl pyrophosphates to (+)- and (-)-bornyl pyrophosphates. |
PubMed: | Investigation of isoprenoid benzoates and naphthoates by reversed-phase liquid chromatography. Isocratic elution characteristics of benzoates and naphthoates of C5-C20 terpenoid alcohols. |
PubMed: | Biosynthesis of monoterpenes: preliminary characterization of bornyl pyrophosphate synthetase from sage (Salvia officinalis) and demonstration that Geranyl pyrophosphate is the preferred substrate for cyclization. |
PubMed: | Formation of 3-hexaprenyl-4-hydroxybenzoate by matrix-free mitochondrial membrane-rich preparations of yeast. |
PubMed: | Purification and characterization of two forms of geranyl transferase from Ricinus communis. |
PubMed: | 3-Hydroxy-3-methylglutaryl CoA reductase and mevalonate kinase of Neurospora crassa. |
PubMed: | The purification and properties of pig liver geranyl pyrophosphate synthetase. |
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