Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.01000 to 1.04000 @ 20.00 °C.
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Pounds per Gallon - (est).: | 8.414 to 8.664
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Refractive Index: | 1.50000 to 1.51000 @ 20.00 °C.
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Boiling Point: | 229.00 to 232.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.100000 mmHg @ 25.00 °C. (est) |
Flash Point: | 173.00 °F. TCC ( 78.33 °C. )
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logP (o/w): | 2.924 (est) |
Soluble in: |
| alcohol | | water, 229.6 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: nutty |
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| roasted nutty |
Odor Description: at 0.10 % in propylene glycol. | slightly roasted nut |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents |
Recommendation for 2-ethoxy-3-isopropyl pyrazine usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 24 |
Click here to view publication 24 |
| average usual ppm | average maximum ppm |
baked goods: | 0.00010 | 0.00050 |
beverages(nonalcoholic): | 0.00001 | 0.00005 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | 0.00300 | 0.02000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | 0.00300 | 0.02000 |
other grains: | 0.00300 | 0.02000 |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | 0.00300 | 0.02000 |
reconstituted vegetables: | - | - |
seasonings / flavors: | 0.00300 | 0.02000 |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
References:
Other Information:
Potential Blenders and core components note
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For Odor |
No odor group found for these |
| sulfuryl octanoate | FL/FR |
| sulfuryl butyrate | FL/FR |
| sulfuryl decanoate | FL/FR |
| sulfuryl hexanoate | FL/FR |
| sulfuryl isobutyrate | FL/FR |
| sulfuryl propionate | FL/FR |
| valeraldehyde dibutyl acetal | FL/FR |
| valeraldehyde propylene glycol acetal | FL/FR |
alcoholic |
| propyl alcohol | FL/FR |
aldehydic |
| nonanal (aldehyde C-9) | FL/FR |
amber |
| ambroxan | FL/FR |
balsamic |
2- | acetyl furan | FL/FR |
(E)- | benzyl tiglate | FL/FR |
| propyl benzoate | FL/FR |
bready |
| coffee furanone | FL/FR |
| furfural | FL/FR |
buttery |
| acetyl propionyl | FL/FR |
3,4- | hexane dione | FL/FR |
camphoreous |
| bornyl isobutyrate | FL/FR |
caramellic |
| cyclotene | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| ethyl cyclopentenolone | FL/FR |
| fenugreek absolute | FL/FR |
iso | propenyl pyrazine | FL/FR |
chocolate |
| chocolate pyrazine A | FL/FR |
| cocoa hexenal | FL/FR |
| cocoa pentenal | FL/FR |
2,5- | dimethyl pyrazine | FL/FR |
2- | methoxy-3-methyl pyrazine | FL/FR |
2- | methoxypyrazine | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
cocoa |
2- | methyl butyraldehyde | FL/FR |
coconut |
alpha- | angelica lactone | FL/FR |
delta- | decalactone | FL/FR |
gamma- | heptalactone | FL/FR |
| furfuryl mercaptan | FL/FR |
2- | methyl-3-,5 or 6-(furfuryl thio) pyrazine | FL/FR |
| popcorn pyrimidine | FL/FR |
coumarinic |
| coumane | FL/FR |
earthy |
2- | ethyl-3-methoxypyrazine | FL/FR |
3- | octanol | FL/FR |
ethereal |
| acetal | FL/FR |
fatty |
| coconut absolute | FL/FR |
fermented |
| valeraldehyde | FL/FR |
floral |
para- | cresyl laurate | FL/FR |
| hawthorn carbinol | FL/FR |
ortho- | methyl acetophenone | FL/FR |
fruity |
| allyl 2-ethyl butyrate | FL/FR |
iso | amyl nonanoate | FL/FR |
| benzaldehyde | FL/FR |
| benzyl butyrate | FL/FR |
| bread thiophene | FL/FR |
| methyl valerate | FL/FR |
3- | methyl-2-butenal | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
| tropical thiazole | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| valeriana officinalis root extract | FL/FR |
green |
| benzaldehyde dimethyl acetal | FL/FR |
| butyl lactate | FL/FR |
1- | heptanol | FL/FR |
2- | heptyl furan | FL/FR |
| lilac acetaldehyde | FL/FR |
(E,Z)-2,6- | nonadien-1-ol | FL/FR |
(E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| styralyl acetate | FL/FR |
| tiglaldehyde | FL/FR |
2- | pentyl acetate | FL/FR |
| sulfurol | FL/FR |
medicinal |
| quinoline | CS |
mushroom |
3- | octen-2-ol | FL/FR |
musty |
2- | acetyl pyrrole | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
| cocoa butenal | FL/FR |
| hazelnut pyrazine | FL/FR |
| menthofuran | FL/FR |
naphthyl |
para- | methyl anisole | FL/FR |
ortho- | methyl anisole | FL/FR |
nutty |
3- | acetyl pyridine | FL/FR |
2- | acetyl-3-ethyl pyrazine | FL/FR |
2- | acetyl-3-methyl pyrazine | FL/FR |
2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
2- | acetyl-5-methyl furan | FL/FR |
3,5- | cocoa pyrazine | FL/FR |
3,6- | cocoa pyrazine | FL/FR |
2,3- | dimethyl pyrazine | FL/FR |
4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
2,4- | dimethyl-5-ethyl thiazole | |
2- | ethyl pyrazine | FL/FR |
2- | ethyl-4-methyl thiazole | FL/FR |
| filbert heptenone | FL/FR |
| filbert heptenone B | FL/FR |
| filbert pyrazine | FL/FR |
(E)- | filbertone | FL/FR |
2,6- | lutidine | FL/FR |
| methoxymethyl pyrazine | FL/FR |
2- | methyl pyrazine | FL/FR |
5- | methyl quinoxaline | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
2- | methyl-3-(methyl thio) pyrazine | FL/FR |
2- | methyl-3-ethoxypyrazine | FL/FR |
2- | methyl-3-propyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
| nutty quinoxaline | FL/FR |
| shoyu pyrazine | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
2,4,5- | trimethyl oxazole | FL/FR |
2,3,5- | trimethyl pyrazine | FL/FR |
| vinyl sulfurol | FL/FR |
para-alpha- | dimethyl styrene | FL/FR |
popcorn |
2- | acetyl pyrazine | FL/FR |
2- | acetyl pyridine | FL/FR |
2- | acetyl thiazole | FL/FR |
roasted |
2- | acetyl-2-pyrroline | |
spicy |
3-(2- | furyl) acrolein | FL/FR |
sulfurous |
| benzothiazole | FL/FR |
| furfuryl thioacetate | FL/FR |
S- | furfuryl thioformate | FL/FR |
tobacco |
(E,E/E,Z)- | tobacco cyclohexenone | FL/FR |
tonka |
6- | amyl-alpha-pyrone | FL/FR |
| whiskey lactone | FL/FR |
tropical |
delta- | dodecalactone | FL/FR |
| mesityl oxide | FL/FR |
| tetrahydrofurfuryl alcohol | FL/FR |
woody |
4- | hydroxybenzaldehyde | FL/FR |
| sandalwood oil | FL/FR |
| santalyl acetate | FL/FR |
| santalyl butyrate | FL/FR |
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For Flavor |
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No flavor group found for these |
| acetyl acetaldehyde dimethyl acetal | FL |
2- | acetyl-2-pyrroline | |
(E)- | aconitic acid | FL |
| bornyl isobutyrate | FL/FR |
| butyramide | FL |
| chocolate pyrazine A | FL/FR |
| chocolate pyrazine B | FL |
| coumane | FL/FR |
| cyclohexyl methyl pyrazine | FL |
2,5- | diethyl thiazole | FL |
2,5- | diethyl-4-methyl thiazole | FL |
6,7- | dihydro-2,3-dimethyl-5H-cyclopentapyrazine | FL |
6,7- | dimethyl dihydrocyclopentapyrazine | FL |
| dimethyl dihydrocyclopentapyrazine | FL |
2,5- | dimethyl thiazole | FL |
2,4- | dimethyl-5-ethyl thiazole | |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
2- | ethyl thiazole | FL |
2- | ethyl-3-methoxypyrazine | FL/FR |
(Z+E)-5- | ethyl-4-methyl-2-(2-butyl) thiazoline | FL |
(Z+E)-5- | ethyl-4-methyl-2-(2-methyl propyl) thiazoline | FL |
(E)- | filbertone | FL/FR |
3-(2- | furyl) acrolein | FL/FR |
(E,E)-2,4- | heptadien-1-ol | FL |
2- | hexyl-5 or 6-keto-1,4-dioxane | FL |
2- | methoxypyrazine | FL/FR |
| methyl 2-(methyl thio) acetate | FL |
4- | methyl-1-pentanol | FL |
2- | methyl-2-thiazoline | FL |
2- | methyl-3-,5 or 6-(furfuryl thio) pyrazine | FL/FR |
2- | methyl-3-(methyl thio) pyrazine | FL/FR |
2- | methyl-3-ethoxypyrazine | FL/FR |
| peanut dithiazine | FL |
3- | pentanol | FL |
2- | propyl pyridine | FL |
| pyrazines mixture | FL |
| pyrazinyl methyl sulfide | FL |
| pyrrole | FL |
para- | salicylic acid | FL |
| santalyl butyrate | FL/FR |
| sulfuryl butyrate | FL/FR |
| sulfuryl decanoate | FL/FR |
| sulfuryl hexanoate | FL/FR |
| sulfuryl isobutyrate | FL/FR |
| thiazole | FL |
| valeraldehyde propylene glycol acetal | FL/FR |
ortho- | vinyl anisole | FL |
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5- | acetyl-2,3-dihydro-1,4-thiazine | FL |
| sulfuryl formate | FL |
| sulfuryl octanoate | FL/FR |
| sulfuryl propionate | FL/FR |
| valeraldehyde dibutyl acetal | FL/FR |
alcoholic |
| propyl alcohol | FL/FR |
aldehydic |
| nonanal (aldehyde C-9) | FL/FR |
alliaceous |
2- | methyl thioacetaldehyde | FL |
| tropical thiazole | FL/FR |
anisic |
ortho- | methyl acetophenone | FL/FR |
apple |
(E,Z)-2,6- | nonadien-1-ol | FL/FR |
balsamic |
(E)- | benzyl tiglate | FL/FR |
bitter |
| paullinia cupana seed extract | FL |
bready |
2- | propionyl thiazole | FL |
brown |
| furfural | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
burnt |
2- | methyl quinoxaline | FL |
iso | propenyl pyrazine | FL/FR |
2,4,5- | trimethyl oxazole | FL/FR |
buttery |
| butyroin | FL |
3,4- | hexane dione | FL/FR |
camphoreous |
ortho- | methyl anisole | FL/FR |
caramellic |
| cyclotene | FL/FR |
| fenugreek absolute | FL/FR |
cocoa |
| cocoa hexenal | FL/FR |
coconut |
delta- | decalactone | FL/FR |
coffee |
| difurfuryl ether | FL |
2- | ethyl-4-methyl thiazole | FL/FR |
| furfuryl mercaptan | FL/FR |
2-iso | propyl pyrazine | FL |
corn |
2- | acetyl pyridine | FL/FR |
2- | acetyl thiazole | FL/FR |
2- | acetyl-2-thiazoline | FL |
| popcorn pyrimidine | FL/FR |
creamy |
6- | amyl-alpha-pyrone | FL/FR |
alpha- | angelica lactone | FL/FR |
delta- | dodecalactone | FL/FR |
4- | hydroxybenzaldehyde | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
dairy |
2- | pentyl acetate | FL/FR |
earthy |
2- | methyl-3-propyl pyrazine | FL/FR |
ethereal |
| allyl 2-ethyl butyrate | FL/FR |
fatty |
| coconut absolute | FL/FR |
(E,E)-2,4- | decadienal | FL |
2- | heptyl furan | FL/FR |
(E,E)-2,4- | nonadienal | FL |
fishy |
4,5- | dimethyl thiazole | FL |
floral |
| cocoa pentenal | FL/FR |
fruity |
| benzaldehyde | FL/FR |
| benzyl butyrate | FL/FR |
| bread thiophene | FL/FR |
2,4- | hexadien-1-ol | FL |
| lilac acetaldehyde | FL/FR |
(E,E)- | methyl sorbate | FL |
| methyl valerate | FL/FR |
3- | methyl-2-butenal | FL/FR |
| propyl benzoate | FL/FR |
| styralyl acetate | FL/FR |
| tiglaldehyde | FL/FR |
| valeriana officinalis root extract | FL/FR |
fusel |
2- | methyl butyraldehyde | FL/FR |
green |
| benzaldehyde dimethyl acetal | FL/FR |
| butyl lactate | FL/FR |
| cocoa butenal | FL/FR |
| dihydroxyacetophenone (mixed isomers) | FL |
2,5- | dimethyl thiophene | FL |
4- | methyl thiazole | FL |
2- | methyl-5-isopropyl pyrazine | FL |
(E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
2- | propyl pyrazine | FL |
2- | vinyl pyrazine | FL |
jammy |
| ethyl cyclopentenolone | FL/FR |
lactonic |
gamma- | heptalactone | FL/FR |
meaty |
| benzothiazole | FL/FR |
2,6- | dimethyl thiophenol | FL |
| sulfurol | FL/FR |
mushroom |
3- | octen-2-ol | FL/FR |
musty |
2,5- | dimethyl pyrazine | FL/FR |
2- | ethoxythiazole | FL |
| hazelnut pyrazine | FL/FR |
| menthofuran | FL/FR |
3- | octanol | FL/FR |
| propionaldehyde | FL |
| shoyu pyrazine | FL/FR |
2,3,5- | trimethyl pyrazine | FL/FR |
naphthyl |
para- | methyl anisole | FL/FR |
nutty |
| acetal | FL/FR |
2- | acetyl furan | FL/FR |
3- | acetyl pyridine | FL/FR |
2- | acetyl pyrrole | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
2- | acetyl-3-ethyl pyrazine | FL/FR |
2- | acetyl-3-methyl pyrazine | FL/FR |
2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
2- | acetyl-5-methyl furan | FL/FR |
| aconitic acid | FL |
2- | butyl-2-butenal | FL |
3,5- | cocoa pyrazine | FL/FR |
3,5(6)- | cocoa pyrazine | FL |
3,6- | cocoa pyrazine | FL/FR |
| coffee furanone | FL/FR |
3,5- | diethyl-2-methyl pyrazine | FL |
2,5- | diethyl-3-methyl pyrazine | FL |
2,3- | dimethyl pyrazine | FL/FR |
4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
2,4- | dimethyl-5-vinyl thiazole | FL |
2- | ethyl pyrazine | FL/FR |
1- | ethyl-2-acetyl pyrrole | FL |
| filbert heptenone | FL/FR |
| filbert heptenone B | FL/FR |
| filbert pyrazine | FL/FR |
european | hazelnut oleoresin | FL |
2,6- | lutidine | FL/FR |
2- | methoxy-3-methyl pyrazine | FL/FR |
| methoxymethyl pyrazine | FL/FR |
2- | methyl pyrazine | FL/FR |
5- | methyl quinoxaline | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
| nutty quinoxaline | FL/FR |
| nutty thiazole | FL |
| peanut oxazole | FL |
| sesame distillates | FL |
| tetrahydrofurfuryl alcohol | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
(E,E/E,Z)- | tobacco cyclohexenone | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
| vinyl sulfurol | FL/FR |
phenolic |
2- | hydroxyisophorone | FL |
popcorn |
2- | propionyl-2-thiazoline | FL |
potato |
| mesityl oxide | FL/FR |
roasted |
2- | acetyl pyrazine | FL/FR |
| ethyl 3-(furfuryl thio) propionate | FL |
| furfuryl thioacetate | FL/FR |
smoky |
| prosopis juliflora wood extract | FL |
solvent |
1- | heptanol | FL/FR |
spicy |
para-alpha- | dimethyl styrene | FL/FR |
| hawthorn carbinol | FL/FR |
sulfurous |
S- | furfuryl thioformate | FL/FR |
sweet |
2- | acetyl-3-methyl thiophene | FL |
toasted |
| acetyl propionyl | FL/FR |
waxy |
para- | cresyl laurate | FL/FR |
winey |
iso | amyl nonanoate | FL/FR |
5- | ethyl-2-methyl pyridine | FL |
| valeraldehyde | FL/FR |
woody |
| ambroxan | FL/FR |
| sandalwood oil | FL/FR |
| santalyl acetate | FL/FR |
| whiskey lactone | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | ethoxy-3-(1-methyl ethyl) pyrazine | 2- | ethoxy-3-(1-methylethyl) pyrazine | 2- | ethoxy-3-isopropylpyrazine | 2- | ethoxy-3-propan-2-ylpyrazine | | pyrazine, 2-ethoxy-3-(1-methylethyl)- | | pyrazine,2-ethoxy-3-(1-methylethyl)- |
Articles:
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