Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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Odor Type: alliaceous |
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Odor Strength: | very high , recommend smelling in a 0.01 % solution or less |
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Substantivity: | 8 hour(s) at 100.00 % |
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| cabbage gassy sweet onion |
Odor Description: at 0.10 % in propylene glycol. | cabbage natural gas sweet onion |
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Flavor Type: alliaceous |
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| alliaceous fresh meaty onion sulfurous |
Taste Description:
| alliaceous fresh meaty onion sulfurous |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Advanced Biotech |
PROPYL MERCAPTAN SYNTHETIC
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Augustus Oils |
Propyl Mercaptan
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Services |
Beijing Lys Chemicals |
1-Propanethiol
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Charkit Chemical |
PROPYL MERCAPTAN
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Chevron Phillips |
n-Propyl Mercaptan
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DeLong Chemicals America |
Propanethiol
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FCI SAS |
PROPYL MERCAPTAN
Odor: Onion |
Jinan Enlighten Chemical Technology(Wutong Aroma ) |
Propane-1-thiol, Kosherk
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Lluch Essence |
PROPYL MERCAPTAN NATURAL
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Lluch Essence |
PROPYL MERCAPTAN
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Natural Advantage |
Propyl Mercaptan Nat
Flavor: alliaceous, fresh, meaty, onion, sulphurous |
Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries |
Penta International |
PROPYL MERCAPTAN NATURAL
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Penta International |
PROPYL MERCAPTAN
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Prodasynth |
PROPYL MERCAPTAN
(> 98%) |
Riverside Aromatics |
PROPYL MERCAPTAN, NATURAL
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Santa Cruz Biotechnology |
For experimental / research use only. |
1-Propanethiol
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Sigma-Aldrich |
1-Propanethiol, natural, ≥98%, FG
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Certified Food Grade Products |
Sigma-Aldrich |
Propyl mercaptan, ≥98%
Odor: vegetable; sulfurous; alliaceous (onion, garlic) |
Synerzine |
1-Propyl Mercaptan
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TCI AMERICA |
For experimental / research use only. |
1-Propanethiol >98.0%(GC)
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Tengzhou Jitian Aroma Chemiclal |
Propyl Mercaptan
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Tengzhou Xiang Yuan Aroma Chemicals |
Propanethiol
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United International |
Propyl Mercaptan
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WholeChem |
1-Propanethiol
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 11 - Highly flammable. R 22 - Harmful if swallowed. R 37/38 - Irritating to respiratory system and skin. R 41 - Risk of serious damage to eyes. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 20/21 - When using do not eat, drink or smoke. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 33 - Take precautionary measures against static discharge. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
gavage-rat LD50 1790 mg/kg (Fairchild & Stokinger, 1958)
intraperitoneal-rat LD50 515 mg/kg BEHAVIORAL: COMA
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
gavage-rat LD50 134 mg/kg Referred to as 3-mercapto-1-propanol in reference (Elf Atochem, 1981b)
oral-rat LD50 1790 mg/kg BEHAVIORAL: COMA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
inhalation-rat LC50 7300 ppm/4H BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
inhalation-mouse LC50 4010 ppm/4H SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 2.20 (μg/capita/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 10 |
Click here to view publication 10 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.92900 |
beverages(nonalcoholic): | - | 1.00000 |
beverages(alcoholic): | - | 1.00000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | 1.25000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 1.00000 |
fruit ices: | - | 1.00000 |
gelatins / puddings: | - | 1.00000 |
granulated sugar: | - | - |
gravies: | - | 2.20000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 2.20000 |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | 3.00000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on the safety and efficacy of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups (chemical group 20) when used as flavourings for all animal species View page or View pdf |
EPI System: | View |
NIOSH International Chemical Safety Cards: | search |
NIOSH Pocket Guide: | search |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 107-03-9 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 7848 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 2402 |
WGK Germany: | 3 |
| propane-1-thiol |
Chemidplus: | 0000107039 |
EPA/NOAA CAMEO: | hazardous materials |
RTECS: | 107-03-9 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| mercaptan C3 | 1- | mercaptopropane | | NPM | | propane thiol | 1- | propane thiol | | propane-1-thiol | | propanethiol | 1- | propanethiol | N- | propanethiol | | propanethiol natural | 1- | propyl mercaptan | N- | propyl mercaptan | | propyl mercaptan natural | | propyl thiol | | propylthiol | N- | propylthiol | N- | thiopropyl alcohol |
Articles:
PubMed: | Solid phase extraction of trace amounts of silver, cadmium, copper, mercury, and lead in various food samples based on ethylene glycol bis-mercaptoacetate modified 3-(trimethoxysilyl)-1-propanethiol coated Fe3O4 nanoparticles. |
PubMed: | Magnetic nanoparticles solid phase extraction for determination of ochratoxin A in cereals using high-performance liquid chromatography with fluorescence detection. |
PubMed: | Identification of muscadine wine sulfur volatiles: pectinase versus skin-contact maceration. |
PubMed: | Novel approach for the determination of volatile compounds in processed onion by headspace gas chromatography-mass spectrometry (HS GC-MS). |
PubMed: | Removal of mercaptans from a gas stream using continuous adsorption-regeneration. |
PubMed: | Aqueous photoreduction of oxidized mercury species in presence of selected alkanethiols. |
PubMed: | Direct electrochemistry of hemoglobin adsorbed on self-assembled monolayers with different head groups or chain length. |
PubMed: | Nucleophilic reactivity of thiolate, hydroxide and phenolate ions towards a model O-arylated diazeniumdiolate prodrug in aqueous and cationic surfactant media. |
PubMed: | ZnO nanorod array solid phase micro-extraction fiber coating: fabrication and extraction capability. |
PubMed: | Density functional characterization of adsorption and decomposition of 1-propanethiol on the Ga-rich GaAs (001) surface. |
PubMed: | A molecular dynamics study on heat transfer characteristics at the interfaces of alkanethiolate self-assembled monolayer and organic solvent. |
PubMed: | Kinetic and theoretical study of the reaction of Cl atoms with a series of linear thiols. |
PubMed: | Companion animals as sentinels for community exposure to industrial chemicals: the Fairburn, GA, propyl mercaptan case study. |
PubMed: | Chemical analysis of polycyclic aromatic hydrocarbons by surface-enhanced Raman spectroscopy. |
PubMed: | Conformationally specific vacuum ultraviolet mass-analyzed threshold ionization spectroscopy of alkanethiols: structure and ionization of conformational isomers of ethanethiol, isopropanethiol, 1-propanethiol, tert-butanethiol, and 1-butanethiol. |
PubMed: | Determination of volatile organic sulfur compounds in the air at sewage management areas by thermal desorption and gas chromatography-mass spectrometry. |
PubMed: | Disposition and metabolism of dipropyl disulphide in vivo in rat. |
PubMed: | [Determination and distribution of sulfur compounds in coked gasoline by gas chromatography-sulfur chemiluminescence detection]. |
PubMed: | Ruminal fermentation of propylene glycol and glycerol. |
PubMed: | Targeting the cerebrovascular large neutral amino acid transporter (LAT1) isoform using a novel disulfide-based brain drug delivery system. |
PubMed: | Assembly dynamics and detailed structure of 1-propanethiol monolayers on Au(111) surfaces observed real time by in situ STM. |
PubMed: | Transferable potentials for phase equilibria. 8. United-atom description for thiols, sulfides, disulfides, and thiophene. |
PubMed: | A comparative kinetic study of modified Pt(dppf)Cl2 complexes and their interactions with L-cys and L-met. |
PubMed: | Determination of organoarsenic warfare agents in sediment samples from Skagerrak by gas chromatography-mass spectrometry. |
PubMed: | Surface reactions of 1-propanethiol on GaAs(100). |
PubMed: | On-column derivatization-capillary electrochromatography with o-phthalaldehyde/alkylthiol for assay of biogenic amines. |
PubMed: | Effects of various thiol molecules added on morphology of dendrimer-gold nanocomposites. |
PubMed: | Electroencephalographic changes during intravenous olfactory stimulation in humans. |
PubMed: | Molar Refractivity and Connectivity Index Correlations for Henry's Law Virial Coefficients of Odorous Sulfur Compounds on Carbon and for Gas-Chromatographic Retention Indices. |
PubMed: | Cloning and characterization of a bifunctional leukotriene A(4) hydrolase from Saccharomyces cerevisiae. |
PubMed: | Chemisorption on Thiol-Silicas: Divalent Cations as a Function of pH and Primary Amines on Thiol-Mercury Adsorbed |
PubMed: | Investigation of the inhibition of leukotriene A4 hydrolase. |
PubMed: | Somatostatin depleting potency of cysteamine-related thiols and amines in the rat: structure-activity relation. |
PubMed: | Acute health effects from community exposure to N-propyl mercaptan from an ethoprop (Mocap)-treated potato field in Siskiyou County, California. |
PubMed: | Acute health effects from community exposure to N-propyl mercaptan from an ethoprop (Mocap)-treated potato field in Siskiyou County, California. |
PubMed: | Spectroscopic detection of iminocyclophosphamide and its possible role in cyclophosphamide metabolism. |
PubMed: | Reactions of mercaptans with cytochrome c oxidase and cytochrome c. |
PubMed: | Magnetic circular dichroism of ferrous carbonyl adducts of cytochromes P-450 and P-420 and their synthetic models: further evidence for mercaptide as the fifth ligand to iron. |
PubMed: | Specific inhibition of sclerotium formation by 2-mercaptoethanol and related sulfhydryl compounds in Sclerotium rolfsii. |
PubMed: | Titrimetric determination of mercaptans with chloramine-T. |
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